Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis

Breast Cancer Research and Treatment

Volumn 125, Issue 2, 2011, Pages 421-430

  Pollari, Sirkku ^a   Käkönen, Sanna Maria ^b,e   Edgren, Henrik ^c   Wolf, Maija ^c   Kohonen, Pekka ^a   Sara, Henri ^a   Guise, Theresa ^d   Nees, Matthias ^a   Kallioniemi, Olli ^c  

^a TURKU CENTRE FOR BIOTECHNOLOGY   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c UNIVERSITY OF HELSINKI   (Finland)

^d INDIANA UNIVERSITY   (United States)

^e Amgen AB Finland   (Finland)

Author keywords

Bone metastasis; Breast cancer; l serine; Osteoclast

Indexed keywords

AMINOTRANSFERASE; PHOSPHOGLYCERATE DEHYDROGENASE; PHOSPHOSERINE AMINOTRANSFERASE 1; PHOSPHOSERINE PHOSPHATASE; SERINE; UNCLASSIFIED DRUG;

AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE METASTASIS; BREAST CANCER; CANCER CELL CULTURE; CANCER RELAPSE; CELL PROLIFERATION; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOCLAST; OSTEOCLASTOGENESIS; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; BLOTTING, WESTERN; BONE NEOPLASMS; BONE RESORPTION; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; NEOPLASM TRANSPLANTATION; OSTEOCLASTS; PHOSPHOGLYCERATE DEHYDROGENASE; PHOSPHORIC MONOESTER HYDROLASES; POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SERINE; SURVIVAL RATE; TRANSAMINASES;

EID: 78650996423     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-0848-5     Document Type: Article

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