Immunological features and efficacy of a multi-epitope vaccine CTB-UE against H. pylori in BALB/c mice model

Applied Microbiology and Biotechnology

Volumn 98, Issue 8, 2014, Pages 3495-3507

  Guo, Le ^a,b   Yin, Runting ^a,c   Liu, Kunmei ^a,b   Lv, Xiaobo ^a   Li, Yonghong ^b   Duan, Xiangguo ^b   Chu, Yuankui ^b   Xi, Tao ^a   Xing, Yingying ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b NINGXIA MEDICAL UNIVERSITY   (China)

^c NANTONG UNIVERSITY   (China)

Author keywords

Efficacy; Epitope vaccine; Helicobacter pylori; Immunogenicity; Specificity

Indexed keywords

ANTIBODIES; ENZYME INHIBITION; EPITOPES; IMMUNIZATION; MAMMALS; METABOLISM; UREA;

CHOLERA TOXIN B SUBUNIT; EFFICACY; HELICOBACTER PYLORI; HELICOBACTER PYLORI INFECTIONS; IMMUNOGENICITY; NEUTRALIZING ANTIBODIES; SPECIFICITY; THERAPEUTIC EFFICACY;

VACCINES;

CHOLERA TOXIN B SUBUNIT; FREUND ADJUVANT; GAMMA INTERFERON; HELICOBACTER PYLORI VACCINE; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; INTERLEUKIN 17; INTERLEUKIN 4; NEUTRALIZING ANTIBODY; UREASE; BACTERIAL VACCINE; BACTERIUM ANTIBODY; CHOLERA TOXIN; EPITOPE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; RECOMBINANT VACCINE; SECRETORY IMMUNOGLOBULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ANTIGENICITY; ARTICLE; B LYMPHOCYTE; BACTERIAL COLONIZATION; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG PURIFICATION; ENZYME ACTIVITY; HELICOBACTER INFECTION; HELICOBACTER PYLORI; IMMUNOGENICITY; IMMUNOREACTIVITY; INFLAMMATORY INFILTRATE; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ANIMAL; BACTERIAL LOAD; BAGG ALBINO MOUSE; BLOOD; DISEASE MODEL; GENETICS; IMMUNOLOGY; MICROBIOLOGY; MUCOSAL IMMUNITY; ORAL DRUG ADMINISTRATION; STOMACH;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL LOAD; BACTERIAL VACCINES; CD4-POSITIVE T-LYMPHOCYTES; CHOLERA TOXIN; DISEASE MODELS, ANIMAL; EPITOPES, B-LYMPHOCYTE; EPITOPES, T-LYMPHOCYTE; HELICOBACTER PYLORI; IMMUNITY, MUCOSAL; IMMUNOGLOBULIN A; IMMUNOGLOBULIN A, SECRETORY; IMMUNOGLOBULIN G; MICE; MICE, INBRED BALB C; STOMACH; UREASE; VACCINES, SYNTHETIC;

EID: 84898848909     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-013-5408-6     Document Type: Article

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