Systemic immunization with urease protects mice against Helicobacter pylori infection

Vaccine

Volumn 16, Issue 8, 1998, Pages 850-856

  Guy, Bruno ^b   Hessler, Catherine ^a   Fourage, Sophie ^a   Haensler, Jean ^a   Vialon Lafay, Elisabeth ^a   Rokbi, Bachra ^a   Millet, Marie José Quentin ^a  

^a Research Department   (France)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN; ESCHERICHIA COLI ENTEROTOXIN; LIPOPEPTIDE; RECOMBINANT ENZYME; SAPONIN; UREASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; HELICOBACTER PYLORI; HELPER CELL; IMMUNE RESPONSE; IMMUNIZATION; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, ORAL; ANIMALS; BACTERIAL PROTEINS; BACTERIAL VACCINES; FEASIBILITY STUDIES; GASTRITIS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; INJECTIONS, SUBCUTANEOUS; MICE; STOMACH; TH1 CELLS; TH2 CELLS; UREASE; VACCINATION; VACCINES, SYNTHETIC;

EID: 0032078331     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(97)00258-2     Document Type: Article

References (34)

1. 1 Axon, A.T.R. and Quina, M. Ten-year milestones. In The Year in Helicobacter pylori, 1994. Current Science Ltd, London. 1995, pp. 1-5.
2. 2 Marchetti, M., Arico, B., Burroni, D., Figura, N., Rappuoli, R. and Ghiara, P. Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science 1995, 267, 1655-1658.
3. 3 Eaton, K.A. and Krakowka, S. Chronic active gastritis due to Helicobacter pylori in immunized gnotobiotic piglets. Gastroenterology 1992, 103, 1580.
4. 4 Dubois, A., Berg, D.E. and Incecik, E.T. et al. Transient and persistent experimental infection of non-human primates with Helicobacter pylon implications for human disease. Infect. Immun. 1996, 64, 2885-2891.
5. 5 Lee, A. Prevention of H. pylori infection. Scand. J. Gastroenterol. 1996. 31, 11-15.
6. 6 Czinn, S.J., Cai, A and Nedrud, J. Protection of germ-free mice from infection by Helicobacter felis after oral or passive IgA immunization. Vaccine 1993, 11, (6), 637-642.
7. 7 Ferrero, R.L., Thiberge, J-M., Huerre, M. and Labigne, A. Recombinant antigens prepared from the urease subunits of Helicobacter spp.: evidence of protection in a mouse model of gastric infection. Infect. Immun. 1994, 62, (11), 4981-4989.
8. 8 Lee, C.K., Weltzin, R. and Thomas, W.D. et al. Oral immunization with recombinant Helicobacter pylori urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felis. J. Infect. Dis. 1995, 172, 161-172.
9. 9 Michetti, P., Corthesy-Theulaz, I. and Davin, C. et al. Immunization of BALB/c mice against H. felis infection with H. pylori urease. Gastoenterology 1994, 107, 1002-1011.
10. 10 Eaton, K.A. and Krakowka, S. Vaccination of gnotobiotic piglets against H. pylori. Abstract 1B:14, H. pylori Meeting, Copenhagen, 1996.
11. 11 Pappo, J., Thomas, W.D., Kabok, Z., Taylor, N.S., Murphy, J.C. and Fox, J.G. Effect of oral immunization with recombinant urease on murine Helicobacter felis gastritis. Infect. Immun. 1995, 63, (4), 1246-1252.
12. 12 D'Elios, M.M., Manghetti, M. and de Carli, M. Th1 effector cels specific for H. pylori in the gastric antrum of patients with peptic ulcer disease. J. Immun. 1997, 158, 962-967.
13. 13 Mohammadi, M., Czinn, S. Redline, R. and Nedrud, J. Helicobacter specific cell-mediated immunity responses display a predominant Th1 phenotype and promote a delayed type hypersensitivity response in the stomachs of mice. J. Immun. 1996, 156, 4729-4738.
14. 14 Häberle, H., Kubin, M., Trinchieri, G. et al. The regulation of activated Helper T cells in the gastric mucosa during infection with H. pylori. Abstract 199. European H. pylori Study Group, 1995.
15. 15 Radcliff, F.J., Ramsay, A.J. and Lee. A. A mixed Th1/Th2 response may be necessary for effective immunity against Helicobacter. Abstract W3.2.7. Mucosal Immunology Meeting Sydney 1997. Immun. Cell Biol. 1997, Suppl. 1, A90.
16. 16 Kensil, C.R., Patel, U., Lennick, M. and Marciani, D. Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex. J. Immun. 1991, 146, 431-437.
17. 17 Kleanthous H., Tibbits, T., Bahios, T.J. et al. In vivo selection of a highly adapted H. pylori isolate and the development of an H. pylori mouse model for studying vaccine efficacy. In: VIIIth International Workshop on Gastroduodenal Pathology and Helicobacter pylori. 7-9th July 1995. Edinburgh, Scotland, UK, 1995.
18. 18 Takahashi, I., Marinaro, M. and Kiyono, H. et al. Mechanisms for mucosal immunogenicity and adjuvancy of E. coli labile enterotoxin. J. Infect. Dis. 1996, 173, 627-635.
19. 19 Dangelat, S. and Kaufmann, S.H.E. Role of Th1 and Th2 cells in bacterial infections. In: Th1 and Th2 Cells in Health and Disease, Chemical Immunology (Ed. Romagnani, S.). Basel. Karger, 1996, Vol. 63, pp. 66-97
20. 20 Cenci, E., Mencacci, A. and Spaccapelo, R. et al. Th1 and Th2 like responses are present in mice with gastric candidiasis but protective immunity is associated with Th1 development. J. Infect. Dis. 1995, 171, 1279-1288.
21. 21 Rudmann, D., Eaton, K. and Krakowka, S. Ultrastructural properties of H. pylori adherence in gnotobiotic piglets Infect. Immun. 1992, 60, (5), 2121-2124.
22. 22 Rathbone, B.J., Wyatt, J.I. and Worsley, B.W. et al. Systemic and local antibody responses to gastric Campylobacter pyloridis in non-ulcer dyspepsia. Gut 1986, 27, 642-647.
23. 23 Crabtree, J.E., Taylor, J.D. and Wyatt, J.I. et al. Mucosal IgA recognition of Helicobacter pylori 120kDa protein, peptic ulceration, and gastric pathology. Lancet 1991, 338, 332-335.
24. 24 Wirth, H.P., Yang, M., Karita, M. and Blaser, M.J. Expression of the human cell surface glycoconjugates Lewis X and Lewis Y by H. pylori isolates is related to cagA status Infect. Immun. 1996, 64, 4598-4605.
25. 25 Blaser, M.J. and Parsonnet, J. Parasitism by the "slow" bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia. J. Clin. Invest. 1994, 94, 4-8.
26. 26 Ermak, T.H., Kleanthous, H.K and Myers, G. et al. Oral immunization of mice with recombinant H. pylori urease: corpus gastritis after challenge with H. felis is due to residual bacteria. Abstract W3.2.14. Mucosal Immunology Meeting Sydney. Immun. Cell Biol. 1997, 1, A92.
27. 27 Forsthuber, T., Yipand, H.C. and Lehmann, P. Induction of Th1 and Th2 immunity in neonatal mice. Science 1996, 271, 1728-1730.
28. 28 Robbins, J.B., Schneerson, R. and Szu, S.C Perspective: hypothesis: serum IgG antibody is sufficient to confer protection against infectious diseases by inactivating the inoculum. J. Infect. Dis. 1995, 171, 1387-1398.
29. 29 Ferrera, R., Thiberge, J.M. and Labigne, A. Local immunoglobulin G antibodies in the stomach may contribute to immunity against Helicobacter infection in mice. Gastroenterology 1997, 113, 185-194.
30. 30 Shroff, K.E., Meslin, K. and Cebra, J. Commensal enteric bacteria engender a self-limiting humoral mucosal immune response while permanently colonizing the gut. Infect. Immun. 1995, 63, 3904-3913.
31. 31 Bogstedt, A.K., Nava, S., Wadström, T. and Hammarström, L. Helicobacter pylori infections in IgA deficiency: lack of role for the scretory immune system. Clin. Exp. Immun. 1996, 105, 202-204.
32. 32 Wirth, H.P., Flury, R., Meyenberger, Ch., Amman, R. and Altorfer, J. Suppression von H. pylori durch die local sekretorische Immunantwort?. Schweiz Med. Wochenschr. 1994, 124, 620-625.
33. 33 Lehner, T., Bergmaier, L. and Tao, L. et al. Targeted lymph node Immunization with SIV p27 antigen to elicit genital, rectal and urinary immune responses in nonhuman primates. J. Immun. 1994, 153, 1858-1868.
34. 34 Cohen, D., Ashkenazi, S. and Green, M.S. et al. Double-blind vaccine controlled randomised efficacy trial of an investigational Shigella sonnei conjugate vaccine in young adults. Lancet 1997, 349, 155-158.