Immunization of mice with urease vaccine affords protection against Helicobacter pylori infection in the absence of antibodies and is mediated by MHC class II-restricted responses

Journal of Experimental Medicine

Volumn 188, Issue 12, 1998, Pages 2277-2288

  Ermak, Thomas H ^a   Giannasca, Paul J ^a   Nichols, Richard ^a   Myers, Gwendolyn A ^a   Nedrud, John ^b   Weltzin, Richard ^a   Lee, Cynthia K ^a   Kleanthous, Harold ^a   Monath, Thomas P ^a  

^a Acambis   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Adjuvants; Gastric mucosa; Helicobacter pylori; Knockout mice; T cells

Indexed keywords

BACTERIAL VACCINE; IMMUNOLOGICAL ADJUVANT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; UREASE;

ACTIVE IMMUNIZATION; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; ESCHERICHIA COLI; GASTRITIS; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HOST RESISTANCE; IMMUNOGENICITY; INFECTION PREVENTION; INFECTION RESISTANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STOMACH MUCOSA;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, BACTERIAL; B-LYMPHOCYTES; BACTERIAL VACCINES; FEMALE; GASTRIC MUCOSA; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNITY, MUCOSAL; IMMUNIZATION SCHEDULE; IMMUNOGLOBULINS; LYMPHOID TISSUE; MICE; MICE, KNOCKOUT; SPECIFIC PATHOGEN-FREE ORGANISMS; T-LYMPHOCYTES; UREASE; VACCINATION;

EID: 0032444909     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.12.2277     Document Type: Article

References (7)

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