Protection of mice against gastric colonization by Helicobacter pylori by single oral dose immunization with attenuated Salmonella typhimurium producing urease subunits A and B

Vaccine

Volumn 16, Issue 5, 1998, Pages 460-471

  Gómez Duarte, Oscar G ^a   Lucas, Bernadette ^b   Yan, Zheng Xin ^a   Panthel, Klaus ^a,c   Haas, Rainer ^a,c   Meyer, Thomas F ^a,b  

^a MAX PLANCK INST FÜR BIOLOGIE   (Germany)

^b MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

H. pylori; Protection; Salmonella; Urease; Vaccine

Indexed keywords

LIVE VACCINE; RECOMBINANT VACCINE; SALMONELLOSIS VACCINE; UREASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM COLONY; CONTROLLED STUDY; FEMALE; GASTRITIS; HELICOBACTER PYLORI; IMMUNIZATION; MOLECULAR CLONING; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PEPTIC ULCER; PRIORITY JOURNAL; SALMONELLA;

EID: 0032033279     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(97)00247-8     Document Type: Article

References (61)

1. 1 Warren, J.R. and Marshall, B. Unidentified curved bacilli on gastric epithellium in active chronic gastritis. Lancet 1983, i, 1273-1275.
2. 2 Marschall, B.J. and Warren, J.R. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet 1983, i, 1311-1314.
3. 3 Parsonet, J., Hanssen, S. and Rodriguez, L. et al. Helicobacter pylori infection and gastric lymphoma. W. Engl. J. Med. 1994, 330, 1267-1271.
4. 4 Mussel, T., Isascson, P.G., Crabtree, J.E. and Spencer, J. The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori. Lancet 1993, 342, 571-574.
5. 5 Wotherspoon, A.C., Doglioni, C., Cooper, M. and Robinson, J. Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori. Lancet 1993, 342, 575-577.
6. 6 Tsuda, M., Karita, M., Morshed, M.G., Okita, K. and Nakasaki, T.A. A urease-negative mutant of Helicobacter pylori constructed by allelic exchange mutagenesis lacks the ability to colonize the nude mice stomach. Infect. Immun. 1994, 62, 3586-3589.
7. 7 Eaton, K.A. and Krakowka, S. Effect of gastric pH on urease-dependent colonization of gnobiotic piglets by Helicobacter pylori. Infect. Immun. 1994, 62, 3604-3607.
8. 8 Marschall, B.J., Barret, L., Prakash, C., McCallum, R. and Guerrant, R. Urea protects Helicobacter (Campylobacter) pylori from the bactericidal effect of acid. Gastroenterol. 1990, 99, 269-276.
9. 9 Clyne, M., Labigne, A. and Drumm, B. Helicobacter pylori requires an acidic environment to survive in the presence of urea. Infect. Immun. 1995, 61, 1669-1673.
10. 10 Smoot, D.T., Mobley, H.L., Chappendale, G.R., Lewison, J.F. and Resau, J.H. Helicobacter pylori urease activity is toxic to human gastric epithelial cells. Infect. Immun. 1990, 58, 1992-1994.
11. 11 Ghiara, P., Marchetti, M. and Blaser, M.J. et al. Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease. Infect. Immun. 1995, 63, 4154-4160.
12. 12 Mobley, H.L., Island, M.D. and Hausinger, R.P. Molecular biology of microbial ureases. Microbial Rev. 1995, 59, 451-480.
13. 13 Dent, J.G., McNulty, C.A., Uff, J.S., Gear, M.W, and Wilkinson, S.P. Campylobacter pylori urease: a new serologicai test. Lancet 1988, i, 1002
14. 14 Pappo, J., Thomas, W.D., Kabok, Z., Taylor, N.S., Murphy, J.C. and Fox, J.G. Effect of oral immunization with recombinant urease on murine Helicobacter felis gastritis. Infect. Immun. 1995, 63, 1246-1252.
15. 15 Michetti, P., Corthésy-Theulaz, I. and Davin, C. et al. Immunization of BALB/c mice against Helicobacter felis infection with Helicobacter pylori urease. Gastroenterol. 1994, 107, 1002-1011.
16. 16 Marchetti, M., Aricò, B., Burroni, D., Figura, N., Rapuolli, R. and Ghiara, P. Development of a mouse model of Helicobacter pylori infection that mimics human disease. Science 1995, 267, 1655-1658.
17. 17 Emoto, M., Danbara, H. and Yoskikai, Y. Induction of gamma/ delta T cells in murine salmonellosis by an avirulent but not by an virulent strain of Salmonella choleraesuis. J. Exp. Med. 1992, 176, 363-372.
18. 18 Tacket, C.O., Sztein, M.B. and Losonsky, G.A. et al. Safety of live Oral Salmonella typhi vaccine strains with deletions in hrtA, and aroC aroD and immune response in humans. Infect. Immun. 1997, 65, 452-456.
19. 19 Gilman, R.H., Hornick, R.B. and Woodward, W.E. et a/. Immunity in typhoid fever: evaluation of Ty21a. An epimeraseless mutant of S. typhi as a live oral vaccine. J. Infect. Dis. 1977, 136, 717-723.
20. 20 Wahdan, M.H., Serie, C., Cerisier, Y., Sallam, S. and Germanier, R. A controlled field trial of line Salmonella typhi Ty21a vaccine strain against typhoid: three years results. J. Infect. Dis. 1984, 145, 292-295.
21. 21 Hone, D.M., Harris, A.M., Chatfield, S., Dougan, G. and Levine, M.M. Construction of genetically defined doble aro mutants of Salmonella typhi. Vaccine 1991, 9, 810-816.
22. 22 Tacket, C.O., Hone, D.M., Losonsky, G.A., Guers, L., Edelman, R. and Levine, M.M. Clinical acceptability and immunogenicity of CVD908 Salmonella typhi vaccine strain. Vaccine 1992, 10, 443-446.
23. 23 Levine, M.M. Typhoid fever vaccines. In: Vaccines (Eds Plotkin, S.A. and Mortimer, E.A.). WB Saunders, Philadelphia, 1988, pp. 333-361
24. 24 Hoiseth, S.K. and Stocker, B.A.D. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature 1981, 291, 238-239.
25. 25 Chatfield, S.N., Strugnell, R.A. and Dougan, G. Live Salmonella as vaccines and carriers or foreign antigenic determinants. Vaccine 1989, 7, 495-498.
26. 26 Van, Z.X. and Meyer, T.F. The variation of antigen expression: a natural phenomenon utilised for the construction of live recombinant Salmonella vaccines. Behring Inst. Mitt. 1994, 95, 49-56.
27. 27 Kahrs, A.F., Odenbriet, S., Schmitt, W., Heuermann, D., Meyer, T.F. and Haas, R. An improved TnMax mini-transposon system suitable for sequencing, shuttle mutagenesis and gene fusions. Gene 1995, 167, 53-57.
28. 28 Odenbreit, S., Wieland, B. and Haas, R. Cloning and genetic characterization of Helicobacter pylori catalase and construction of a catalase-deficient mutant strain. J. Bacteriol. 1996, 178, 6960-6967.
29. 29 Elson, C.O., Ealding, W. and Lefkowitz, J. A lavage technique allowing repeated measurement of IgA antibody in mouse intestinal secretions. J. Immunol. Meth. 1984, 67, 101-108.
30. 30 Summers, D.K. and Sherrat, D.J. Multimerization of high copy number plasmids causes instability: ColE1 encodes a determinant essential for plasmid monomerization and stability. Cell 1984, 36, 1097-1103.
31. 31 Sambrook, J., Fritsch, E.F. and Maniatis, T. Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y., 1989
32. 32 NIH consensus development on Helicobacter pylori in peptic ulcer disease. Helicobacter pylori in peptic ulcer disease. JAMA 1994, 272, 65
33. 33 Kawanishi, M., Fukuda, S., Kawaguchi, H., Kohmoto, K., Haruma, K. and Kajiyama, G. Significance of rapid urease test for identification of Helicobacter pylori in comparison with histological and culture studies. J. Gastroenterol. 1995, 30, 16-20.
34. 34 Kamija, S., Taniguchi, I. and Yamamoto, T. et al. Evaluation of rapid urease test for detection of Helicobacter pylori in gastric biopsy specimens. Eur. J. Epidemiol. 1993, 9, 450-452.
35. 35 Conti-Nibali, S., Sterlazzas, C., Fera, M.T., Saitta, G., Tedeschi, A. and Magazzu, G. Helicobacter pylori infection: a simplified diagnostic approach. Am. J. Gastroenterol. 1990, 85, 1573-1575.
36. 36 Gottfried, M.R., Washington, K. and Harrell, L.J. Helicobacter pylori-like microorganisms and chronic active gastritis in ferrets. Am. J. Gastroenterol. 1990, 85, 813-818.
37. 37 Goodman, K.J. and Correa, P. The transmission of Helicobacter pylori. A critical review of the evidence. Intern. J. Epidemiol. 1995, 24, 875-887.
38. 38 Madinier, I.M., Fosse, T.M. and Monteil, R.A. Oral carriage of Helicobacter pylori: a review. J. Periodontol. 1997, 68, 2-6.
39. 39 Pytko-Polonczyk, J., Konturek, S.J., Karczewska, E., Bielanski, W. and Kaczmarczyk-Stachowska, A. Oral cavity and permanent reservoir of Helicobacter pylori and potential source of reinfection. J. Physiol. Pharm. 1996, 47, 121-129.
40. 40 Fox, J.G., Perkins, S., Yan, L., Shen, Z., Attarde, L. and Pappo, J. Local immune response in Helicobacter pylori-infected cats and identification of H. pylori in saliva, gastric fluid, and faeces, Immunol. 1996, 88, 400-406.
41. 41 Perkins, S.E., Van, L.L., Shen, Z., Hayward, A., Murphy, J.C. and Fox, J.G. Use of PCR and culture to detect Helicobacter pylori in naturally infected cats following triple antimicrobial therapy. Antimicrob. Agents Chemother. 1996, 40, 1486-1490.
42. 42 Lerang, F., Moum, B. and Haug, J.B. et al. Highly effective twice-daily triple therapies for Helicobacter pylori infection and peptic ulcer disease: does in vitro metronidazol resistance have any clinical significance?. Am. J. Gastroenterol. 1997, 92, 248-253.
43. 43 Drake, I.M., Axon, T.T. and Clarke, A.M. Ranitidine in a twice daily triple-therapy regimen for the eradication of Helicobacter pylori. Eur. J. Gastroenterol. Hepatol. 1996, 8, 1169-1173.
44. 44 Vasquez, A., Valdez, Y. and Gilman, R.H. et al. Metronidazol and Clarithromycin resistance in Helicobacter pylori determined by measuring MCIs of antimicrobial agents in color indicator egg yolk agar in a miniwell format. J. Clin. Microbiol. 1996, 34, 1232-1234.
45. 45 Jorgensen, M., Daskalopoulos, G., Warburton, V., Mitchell, H.M. and Hazell, S.L. The multiple strain colonization and metronidazol resistance in Helicobacter pylori-infected patients: identification from sequencial and multiple biopsy specimens. J. Infect. Dis. 1996, 174, 631-635.
46. 46 Midolo, P.D., Lambert, J.R. and Turnidge, J. Metronidazol resistance: a predictor of failure of Helicobacter pylori eradication by triple therapy. J. Gastroenterol. Hepatol. 1996, 11, 290-292.
47. 47 Schutze, K., Hentschel, E., Dragosics, B. and Hirscl, A.M. Helicobacter pylori reinfection with identical organisms: transmission by the patients' spouses. Gut 1995, 36, 831-833.
48. 48 Xia, H.X., Windle, H.J., Marshall, D.G., Smith, C.J. and Keane, C.T. Recrudescence of Helicobacter pylori after apparently successful eradication: novel application of ramdomly amplified polymorphic DNA fingerprinting. Gut 1995, 37, 30-34.
49. 49 Goodman, K.J., Correa, P. and Tengana Aux, H.J. et al. Helicobacter infection in the Colombian Andes: a population-based study of transmission pathways. Am. J. Epidemiol. 1996, 144, 290-299.
50. 50 Lee, C.K., Weltzin, R. and Thomas, W.D. et al. Oral Immunization with Recombinant Helicobacter pylory urease induces secretory IgA antibodies and protects mice from challenge with Helicobacter felis. J. Infect. Dis. 1995, 172, 161-172.
51. 51 Barry, M.B., Gómez-Duarte, O.G. and Chatfield, S. et al. Expression and immunogenicity of pertussis toxin S1 subunit-tetanus toxin fragment C fusion in Salmonella typhi vaccine strain CVD 908. Infect. Immun. 1996, 64, 4172-4181.
52. 52 Mohammadi, M., Redline, R., Nedrud, J. and Czinn, S. Role of the host in pathogenesis of Helicobacter-associated gastritis: H. felis infection in inbred and congenic mouse strains. Infect. Immun. 1996, 64, 238-245.
53. 53 Mai, U.E., Perez-Perez, G., Allen, J.G., Wahl, S.M., Blaser, M. and Smith, P. Soluble surface protein from Helicobacter pylori activate monocyte/macrophages by lipopolysacharide independent mechanism. J. Clin. Invest. 1991, 87, 894-900.
54. 54 Appelmelk, B.J., Negrinni, R., Moran, A.P. and Kuipers, E.J. Molecular mimicry between Helicobacter pylori and the host. Trends Microbiol. 1997, 5, 70-73.
55. 55 Blanchard, T.G., Czinn, S.J., Maurer, R., Thomas, W.D., Soman, G. and Nedrud, J.G. Urease-specific monoclonal antibodies prevent Helicobacter felis infection in mice. Infect. Immun. 1995, 63, 1394-1399.
56. 56 Nausiel, C. and Espinasse, M.F. Role of gamma interferon and tumor necrosis factor alpha in resistance to Salmonella typhimurium infection. Infect. Immun. 1992, 60, 450-454.
57. 57 Matroeni, P., Villarreal-Ramos, B. and Hormaeche, C.E. Adoptive transfer of immunity to oral challenge with virulent Salmonella in innately susceptible Balb/c mice requires both immune serum and T cells. Infect. Immun. 1993, 61, 3981-3984.
58. 58 Nakano, Y., Onosuka, K., Terada, Y., Shinomiya, H. and Nakano, M. Protective effect of recombinant tumor necrosis factor alpha in murine salmonelosis. J. Immunol. 1990, 144, 1935-1941.
59. 59 Harokopakis, E., Hajishengallis, G., Greenway, T.E., Russell, M.W. and Michalek, S.M. Mucosal immunogenicity of a recombinant Salmonella typhimurium-cloned heterologous antigen in the absence or presence of coexpressed cholera toxin A2 and B subunits. Infect. Immun. 1997, 65, 1445-1454.
60. 60 Comoy, E.E., Capron, A. and Thyphronitis, G. In vivo induction of type 1 and 2 immune responses against protein antigens. Inter. Immuno. 1997, 9, 523-531.
61. 61 VanCott, J.L., Staats, H.F. and Pascual, D.W. et al. Regulation of mucosal and systemic antibody responses by T helper subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. J. Immunol. 1997, 156, 1504-1514.