Protective efficacy of vaccines based on the Helicobacter suis urease subunit B and γ-glutamyl transpeptidase

Vaccine

Volumn 31, Issue 32, 2013, Pages 3250-3256

  Vermoote, Miet ^a   Flahou, Bram ^a   Pasmans, Frank ^a   Ducatelle, Richard ^a   Haesebrouck, Freddy ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Glutamyl transpeptidase; Helicobacter suis; Mouse model; Urease subunit B; Vaccination

Indexed keywords

BACTERIAL VACCINE; BETA GLUTAMYL TRANSPEPTIDASE; CHOLERA TOXIN; GAMMA GLUTAMYLTRANSFERASE; IMMUNOLOGICAL ADJUVANT; RECOMBINANT GAMMA GLUTAMYLTRANSFERASE; RECOMBINANT PROTEIN; RECOMBINANT UREASE B; UNCLASSIFIED DRUG; UREASE; UREASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ANTIBODY RESPONSE; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL COLONIZATION; BACTERIAL IMMUNITY; BACTERIAL LOAD; BACTERIUM ISOLATE; BLOOD SAMPLING; CELL LYSATE; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; ESCHERICHIA COLI; FEMALE; HELICOBACTER; HELICOBACTER PYLORI; HELICOBACTER SUIS; IMMUNIZATION; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH LESION; STOMACH MUCOSA; WHOLE CELL;

ADJUVANTS, IMMUNOLOGIC; ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, BACTERIAL; ANTIBODY FORMATION; ANTIGENS, BACTERIAL; BACTERIAL VACCINES; CHOLERA TOXIN; CYTOKINES; ESCHERICHIA COLI; FEMALE; GAMMA-GLUTAMYLTRANSFERASE; HELICOBACTER HEILMANNII; HELICOBACTER INFECTIONS; MICE; MICE, INBRED BALB C; RECOMBINANT PROTEINS; STOMACH; UREASE;

EID: 84879462201     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2013.05.047     Document Type: Article

References (28)

1. De Bruyne E., Flahou B., Chiers K., Meyns T., Kumar S., Vermoote M., et al. An experimental Helicobacter suis infection causes gastritis and reduced daily weight gain in pigs. Vet Microbiol 2012, 160:449-454.
2. Barbosa A.J.A., Silvia J.C.P., Nogueira A.M.M.F., Paulino E., Miranda C.R. Higher incidence of Gastrospirillum sp. in swine with gastric ulcer of the pars oesophagea. Vet Pathol 1995, 32:134-139.
3. Roosendaal R., Vos J.H., Roumen T., Van Vugt R., Cattoli G., Bart A., et al. Slaughter pigs are commonly infected with closely related but distinct gastric ulcerative lesion-inducing gastrospirilla. J Clin Microbiol 2000, 38:2661-2664.
4. Haesebrouck F., Pasmans F., Flahou B., Chiers K., Baele M., Meyns T., et al. Gastric helicobacters in domestic animals and nonhuman primates and their significance for human health. Clin Microbiol 2009, 22:202-223.
5. Flahou B., Hellemans A., Meyns T., Duchateau L., Chiers K., Baele M., et al. Protective immunization with homologous and heterologous antigens against Helicobacter suis challenge in a mouse model. Vaccine 2009, 27:1416-1421.
6. Vermoote M., Van Steendam K., Flahou B., Pasmans F., Glibert P., Ducatelle R., et al. Immunization with the immunodominant Helicobacter suis urease subunit B induces partial protection against H. suis infection in a mouse model. Vet Res 2012, 43:72.
7. Haesebrouck F., Pasmans F., Chiers K., Maes D., Ducatelle R., Decostere A. Efficacy of vaccines against bacterial diseases in swine: what can we expect?. Vet Microbiol 2004, 100:255-268.
8. Baele M., Decostere A., Vandamme P., Ceelen L., Hellemans A., Chiers K., et al. Isolation and characterization of Helicobacter suis sp. nov. from pig stomachs. Int J Syst Evol Microbiol 2008, 58:1350-1358.
9. Flahou B., Haesebrouck F., Chiers K., Van Deun K., De Smet L., Devreese B., et al. Gastric epithelial cell death caused by Helicobacter suis and Helicobacter pylori γ-glutamyl transpeptidase is mainly glutathione degradation-dependent. Cell Microbiol 2011, 13:1933-1955.
10. Orlowski M., Meister A. γ-Glutamyl-p-nitroanilide: a new convenient substrate for determination and study of l- and d-γ-glutamyltranspeptidase activities. Biochim Biophys Acta 1963, 73:679-681.
11. Flahou B., De Baere T., Chiers K., Pasmans F., Haesebrouck F., Ducatelle R. Gastric infection with Kazachstania heterogenica influences the outcome of a Helicobacter suis infection in Mongolian gerbils. Helicobacter 2010, 15:67-75.
12. Vermoote M., Pasmans F., Flahou B., Van Deun K., Ducatelle R., Haesebrouck F. Antimicrobial susceptibility pattern of Helicobacter suis strains. Vet Microbiol 2011, 153:339-342.
13. Flahou B., Van Deun K., Pasmans F., Volf J., Rychlik I., Ducatelle R., et al. The immune response of mice after Helicobacter suis infection: strain differences and distinction with Helicobacter pylori. Vet Res 2012, 43:75.
14. -δδCt method. Methods 2001, 25:402-408.
15. Dixon M.F., Genta R.M., Yardley J.H., Correa P. Classification and grading of gastritis: the updated Sydney system. Am J Surg Pathol 1996, 20:1161-1181.
16. Shibayama K., Kamachi K., Nagata N., Yagi T., Nada T., Doi Y., et al. A novel apoptosis-inducing protein from Helicobacter pylori. Mol Microbiol 2003, 47:443-451.
17. Schmees C., Prinz C., Treptau T., Rad R., Hengst L., Voland P., et al. Inhibition of T-cell proliferation by Helicobacter pylori γ-glutamyl transpeptidase. Gastroenterology 2007, 132:1820-1833.
18. Matsumoto Y., Blanchard T.G., Drakes M.L., Basu M., Redline R.W., Levine A.D., et al. Eradication of Helicobacter pylori and resolution of gastritis in the gastric mucosa of IL-10-deficient mice. Helicobacter 2005, 10:407-415.
19. Couper K.N., Blount D.G., Riley E.M. IL-10: the master regulator of immunity of infection. J Immunol 2008, 180:5771-5777.
20. Goto T., Nishizono A., Fujioka T., Ikewaki J., Mifune K., Nasu M. Local secretory immunoglobulin A and postimmunization gastritis correlate with protection against Helicobacter pylori infection after oral vaccination of mice. Infect Immun 1999, 67:2531-2539.
21. Garhart C.A., Redline R.W., Nedrud J.G., Czinn S.J. Clearance of Helicobacter pylori infection and resolution of postimmunization gastritis in a kinetic study of prophylactically immunized mice. Infect Immun 2002, 70:3529-3538.
22. Morihara F., Fujii R., Hifumi E., Nishizono A., Uda T. Effects of vaccination by a recombinant antigen ureB138 (a segment of the β-subunit of urease) against Helicobacter pylori infection. J Med Microbiol 2007, 56:847-853.
23. Becher D., Deutscher M.E., Simpfendorfer K.R., Wijburg O.L., Pederson J.S., Lew A.M., et al. Local recall responses in the stomach involving reduced regulation and expanded help mediate vaccine-induced protection against Helicobacter pylori in mice. Eur J Immunol 2010, 40:2778-2790.
24. Sutton P., Danon S.J., Walker M., Thompson L.J., Wilson J., Kosaka T., et al. Post-immunization gastritis and Helicobacter infection in the mouse: a long term study. Gut 2001, 49:467-473.
25. Liebler-Tenorio E., Pabst R. MALT structure and function in farm animals. Vet Res 2006, 37:257-280.
26. Kuper C.F., Koornstra P.J., Hameleers D.M.H., Biewenga J., Spit B.J., Duijvestijn A.M., et al. The role of nasopharyngeal lymphoid tissue. Immunol Today 1992, 13:219-224.
27. Koornstra P.J., Duijvestijn A.M., Vlek L.F., Marres E.H., van Breda Vriesman P.J. Tonsillar (Waldeyer's ring equivalent) lymphoid tissue in the rat: lymphocyte subset binding to high endothelial venules (HEV) and in situ distribution. Reg Immunol 1992, 4:401-408.
28. Lin J., Mateo K.S., Zhao M., Erickson A.K., Garcia N., He D., et al. Protection of piglets against enteric colibacillosis by intranasal immunization with K88ac (F4ac) fimbriae and heat labile enterotoxin of Escherichia coli. Vet Microbiol 2013, 162:731-739.