Increased pericyte coverage mediated by endothelial-derived fibroblast growth factor-2 and interleukin-6 is a source of smooth muscle-like cells in pulmonary hypertension

Circulation

Volumn 129, Issue 15, 2014, Pages 1586-1597

  Ricard, Nicolas ^a,b   Tu, Ly ^a,b   Le Hiress, Morane ^a,b   Huertas, Alice ^a,b,c   Phan, Carole ^a,b   Thuillet, Raphaël ^a,b   Sattler, Caroline ^a,b,c   Fadel, Elie ^a,b   Seferian, Andrei ^a,b,c   Montani, David ^a,b,c   Dorfmüller, Peter ^a,b   Humbert, Marc ^a,b,c   Guignabert, Christophe ^a,b,d  

^a CENTRE CHIRURGICAL MARIE LANNELONGUE   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c BICÊTRE HOSPITAL   (France)

^d INSERM   (France)

Author keywords

cell communication; endothelilal cells; fibroblast growth factor 2; interleukin 6; pericytes; pulmonary arterial hypertension; transforming growth factor beta

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; INTERLEUKIN 6; NEUTRALIZING ANTIBODY; TRANSFORMING GROWTH FACTOR BETA;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LUNG BLOOD VESSEL; LUNG PARENCHYMA; MOUSE; NEWBORN; NONHUMAN; PERICYTE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER;

CELL COMMUNICATION; ENDOTHELILAL CELLS; FIBROBLAST GROWTH FACTOR 2; INTERLEUKIN-6; PERICYTES; PULMONARY ARTERIAL HYPERTENSION; TRANSFORMING GROWTH FACTOR BETA;

ADULT; ANIMALS; CELL COMMUNICATION; CELL DIFFERENTIATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; FEMALE; FIBROBLAST GROWTH FACTOR 2; HUMANS; HYPERTENSION, PULMONARY; INTERLEUKIN-6; MALE; MICE; MICE, TRANSGENIC; MICROCIRCULATION; MIDDLE AGED; MUSCLE, SMOOTH, VASCULAR; NEOVASCULARIZATION, PHYSIOLOGIC; PERICYTES; PULMONARY CIRCULATION; RATS; RATS, WISTAR; RETINAL VESSELS;

EID: 84898839855     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.113.007469     Document Type: Article

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