Tie2-mediated loss of peroxisome proliferator-activated receptor-γ in mice causes PDGF receptor-β-dependent pulmonary arterial muscularization

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 297, Issue 6, 2009, Pages

  Guignabert, C ^a   Alvira, C M ^a   Alastalo, T P ^a   Sawada, H ^a   Hansmann, G ^a   Zhao, M ^a   Wang, L ^a   El Bizri, N ^a   Rabinovitch, M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Endothelial cells; Platelet derived growth factor; Platelet derived growth factor receptor ; Pulmonary remodeling; Smooth muscle cell

Indexed keywords

ANGIOPOIETIN RECEPTOR; APOLIPOPROTEIN E; IMATINIB; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR;

AMBIENT AIR; ANIMAL EXPERIMENT; ARTERY MUSCLE; ARTICLE; CELL LOSS; CONTROLLED STUDY; ENDOTHELIUM CELL; GENOTYPE; HEART RIGHT VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; SIGNAL TRANSDUCTION; SYSTOLIC BLOOD PRESSURE;

AIR; ANIMALS; ANOXIA; APOLIPOPROTEINS E; BLOOD PRESSURE; CELL SEPARATION; ENDOTHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GENE EXPRESSION REGULATION; HEART VENTRICLES; HUMANS; HYPERTENSION, PULMONARY; HYPERTROPHY; MICE; MYOCYTES, SMOOTH MUSCLE; PPAR GAMMA; PULMONARY ARTERY; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 71949120983     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00199.2009     Document Type: Article

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