-
1
-
-
55449118686
-
Pulmonary vascular disease in the developing world
-
Butrous G, Ghofrani HA, Grimminger F. Pulmonary vascular disease in the developing world. Circulation. 2008;118:1758-1766.
-
(2008)
Circulation
, vol.118
, pp. 1758-1766
-
-
Butrous, G.1
Ghofrani, H.A.2
Grimminger, F.3
-
2
-
-
80054751142
-
The prevalence of pulmonary hypertension in schistosomiasis: A systematic review
-
Ward TJC, Fenwick A, Butrous G. The prevalence of pulmonary hypertension in schistosomiasis: a systematic review. PVRI Review. 2011;3:12-21.
-
(2011)
PVRI Review
, vol.3
, pp. 12-21
-
-
Tjc, W.1
Fenwick, A.2
Butrous, G.3
-
3
-
-
77953312910
-
Schistosomiasis-associated pulmonary hypertension: Pulmonary vascular disease: The global perspective
-
Graham BB, Bandeira AP, Morrell NW, Butrous G, Tuder RM. Schistosomiasis-associated pulmonary hypertension: pulmonary vascular disease: the global perspective. Chest. 2010;137(suppl):20S-29S.
-
(2010)
Chest
, vol.137
, Issue.SUPPL.
-
-
Graham, B.B.1
Bandeira, A.P.2
Morrell, N.W.3
Butrous, G.4
Tuder, R.M.5
-
4
-
-
68049102899
-
Pathology of pulmonary arterial hypertension
-
Tuder RM. Pathology of pulmonary arterial hypertension. Semin Respir Crit Care Med. 2009;30:376-385.
-
(2009)
Semin Respir Crit Care Med
, vol.30
, pp. 376-385
-
-
Tuder, R.M.1
-
5
-
-
0032975870
-
Enhanced Th1 and dampened Th2 responses synergize to inhibit acute granulomatous and fibrotic responses in murine schistosomiasis mansoni
-
Boros DL, Whitfield JR. Enhanced Th1 and dampened Th2 responses synergize to inhibit acute granulomatous and fibrotic responses in murine schistosomiasis mansoni. Infect Immun. 1999;67:1187-1193.
-
(1999)
Infect Immun
, vol.67
, pp. 1187-1193
-
-
Boros, D.L.1
Whitfield, J.R.2
-
6
-
-
0036138379
-
Clinical and immunologic evaluation of 31 patients with acute schistosomiasis mansoni
-
de Jesus AR, Silva A, Santana LB, Magalhães A, de Jesus AA, de Almeida RP, Rêgo MA, Burattini MN, Pearce EJ, Carvalho EM. Clinical and immunologic evaluation of 31 patients with acute schistosomiasis mansoni. J Infect Dis. 2002;185:98-105.
-
(2002)
J Infect Dis
, vol.185
, pp. 98-105
-
-
De Jesus, A.R.1
Silva, A.2
Santana, L.B.3
Magalhães, A.4
De Jesus, A.A.5
De Almeida, R.P.6
Rêgo, M.A.7
Burattini, M.N.8
Pearce, E.J.9
Carvalho, E.M.10
-
7
-
-
62149121988
-
Immunopathogenesis of human schistosomiasis
-
Burke ML, Jones MK, Gobert GN, Li YS, Ellis MK, McManus DP. Immunopathogenesis of human schistosomiasis. Parasite Immunol. 2009;31: 163-176.
-
(2009)
Parasite Immunol
, vol.31
, pp. 163-176
-
-
Burke, M.L.1
Jones, M.K.2
Gobert, G.N.3
Li, Y.S.4
Ellis, M.K.5
McManus, D.P.6
-
8
-
-
4644225081
-
IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent
-
Kaviratne M, Hesse M, Leusink M, Cheever AW, Davies SJ, McKerrow JH, Wakefield LM, Letterio JJ, Wynn TA. IL-13 activates a mechanism of tissue fibrosis that is completely TGF-beta independent. J Immunol. 2004;173:4020-4029.
-
(2004)
J Immunol
, vol.173
, pp. 4020-4029
-
-
Kaviratne, M.1
Hesse, M.2
Leusink, M.3
Cheever, A.W.4
Davies, S.J.5
McKerrow, J.H.6
Wakefield, L.M.7
Letterio, J.J.8
Wynn, T.A.9
-
9
-
-
77956550884
-
Schistosomiasis-induced experimental pulmonary hypertension: Role of interleukin-13 signaling
-
Graham BB, Mentink-Kane MM, El-Haddad H, Purnell S, Zhang L, Zaiman A, Redente EF, Riches DW, Hassoun PM, Bandeira A, Champion HC, Butrous G, Wynn TA, Tuder RM. Schistosomiasis-induced experimental pulmonary hypertension: role of interleukin-13 signaling. Am J Pathol. 2010;177:1549-1561.
-
(2010)
Am J Pathol
, vol.177
, pp. 1549-1561
-
-
Graham, B.B.1
Mentink-Kane, M.M.2
El-Haddad, H.3
Purnell, S.4
Zhang, L.5
Zaiman, A.6
Redente, E.F.7
Riches, D.W.8
Hassoun, P.M.9
Bandeira, A.10
Champion, H.C.11
Butrous, G.12
Wynn, T.A.13
Tuder, R.M.14
-
10
-
-
79958715229
-
Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation
-
Jenkins SJ, Ruckerl D, Cook PC, Jones LH, Finkelman FD, van Rooijen N, MacDonald AS, Allen JE. Local macrophage proliferation, rather than recruitment from the blood, is a signature of TH2 inflammation. Science. 2011;332:1284-1288.
-
(2011)
Science
, vol.332
, pp. 1284-1288
-
-
Jenkins, S.J.1
Ruckerl, D.2
Cook, P.C.3
Jones, L.H.4
Finkelman, F.D.5
Van Rooijen, N.6
MacDonald, A.S.7
Allen, J.E.8
-
11
-
-
79957982619
-
C-kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension
-
Montani D, Perros F, Gambaryan N, Girerd B, Dorfmuller P, Price LC, Huertas A, Hammad H, Lambrecht B, Simonneau G, Launay JM, Cohen-Kaminsky S, Humbert M. C-kit-positive cells accumulate in remodeled vessels of idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med. 2011;184:116-123.
-
(2011)
Am J Respir Crit Care Med
, vol.184
, pp. 116-123
-
-
Montani, D.1
Perros, F.2
Gambaryan, N.3
Girerd, B.4
Dorfmuller, P.5
Price, L.C.6
Huertas, A.7
Hammad, H.8
Lambrecht, B.9
Simonneau, G.10
Launay, J.M.11
Cohen-Kaminsky, S.12
Humbert, M.13
-
12
-
-
0017089008
-
Hypoxia-dependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2- propanol by Chinese hamster ovary cells and KHT tumor cells in vitro and in vivo
-
Varghese AJ, Gulyas S, Mohindra JK. Hypoxia-dependent reduction of 1-(2-nitro-1-imidazolyl)-3-methoxy-2-propanol by Chinese hamster ovary cells and KHT tumor cells in vitro and in vivo. Cancer Res. 1976;36:3761-3765.
-
(1976)
Cancer Res
, vol.36
, pp. 3761-3765
-
-
Varghese, A.J.1
Gulyas, S.2
Mohindra, J.K.3
-
13
-
-
39549087002
-
Pulmonary arterial remodeling induced by a Th2 immune response
-
Daley E, Emson C, Guignabert C, de Waal Malefyt R, Louten J, Kurup VP, Hogaboam C, Taraseviciene-Stewart L, Voelkel NF, Rabinovitch M, Grunig E, Grunig G. Pulmonary arterial remodeling induced by a Th2 immune response. J Exp Med. 2008;205:361-372.
-
(2008)
J Exp Med
, vol.205
, pp. 361-372
-
-
Daley, E.1
Emson, C.2
Guignabert, C.3
De Waal Malefyt, R.4
Louten, J.5
Kurup, V.P.6
Hogaboam, C.7
Taraseviciene-Stewart, L.8
Voelkel, N.F.9
Rabinovitch, M.10
Grunig, E.11
Grunig, G.12
-
14
-
-
0032565859
-
Smad2 role in mesoderm formation, left-right patterning and craniofacial development
-
Nomura M, Li E. Smad2 role in mesoderm formation, left-right patterning and craniofacial development. Nature. 1998;393:786-790.
-
(1998)
Nature
, vol.393
, pp. 786-790
-
-
Nomura, M.1
Li, E.2
-
15
-
-
10644256482
-
Impaired transforming growth factor-beta signaling in idiopathic pulmonary arterial hypertension
-
Richter A, Yeager ME, Zaiman A, Cool CD, Voelkel NF, Tuder RM. Impaired transforming growth factor-beta signaling in idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med. 2004;170:1340-1348.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 1340-1348
-
-
Richter, A.1
Yeager, M.E.2
Zaiman, A.3
Cool, C.D.4
Voelkel, N.F.5
Tuder, R.M.6
-
16
-
-
0033817459
-
Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension
-
Lane KB, Machado RD, Pauciulo MW, Thomson JR, Phillips JA 3rd, Loyd JE, Nichols WC, Trembath RC. Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension. Nat Genet. 2000;26:81-84.
-
(2000)
Nat Genet
, vol.26
, pp. 81-84
-
-
Lane, K.B.1
MacHado, R.D.2
Pauciulo, M.W.3
Thomson, J.R.4
Phillips Iii., J.A.5
Loyd, J.E.6
Nichols, W.C.7
Trembath, R.C.8
-
17
-
-
84894606377
-
Bmpr-ii deficiency does not worsen pulmonary arterial hypertension in the mouse model of chronic schistosomiasis infection
-
Crosby A, Soon E, Jones F, Southwood M, Dunmore B, Dunne D, Morrell NW. Bmpr-ii deficiency does not worsen pulmonary arterial hypertension in the mouse model of chronic schistosomiasis infection. Am J Respir Crit Care Med. 2012;185:A3438.
-
(2012)
Am J Respir Crit Care Med
, vol.185
-
-
Crosby, A.1
Soon, E.2
Jones, F.3
Southwood, M.4
Dunmore, B.5
Dunne, D.6
Morrell, N.W.7
-
18
-
-
80555148923
-
Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease
-
Ma W, Han W, Greer PA, Tuder RM, Toque HA, Wang KK, Caldwell RW, Su Y. Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease. J Clin Invest. 2011;121:4548-4566.
-
(2011)
J Clin Invest
, vol.121
, pp. 4548-4566
-
-
Ma, W.1
Han, W.2
Greer, P.A.3
Tuder, R.M.4
Toque, H.A.5
Wang, K.K.6
Caldwell, R.W.7
Su, Y.8
-
19
-
-
42649136572
-
Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension
-
Zaiman AL, Podowski M, Medicherla S, Gordy K, Xu F, Zhen L, Shimoda LA, Neptune E, Higgins L, Murphy A, Chakravarty S, Protter A, Sehgal PB, Champion HC, Tuder RM. Role of the TGF-beta/Alk5 signaling pathway in monocrotaline-induced pulmonary hypertension. Am J Respir Crit Care Med. 2008;177:896-905.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 896-905
-
-
Zaiman, A.L.1
Podowski, M.2
Medicherla, S.3
Gordy, K.4
Xu, F.5
Zhen, L.6
Shimoda, L.A.7
Neptune, E.8
Higgins, L.9
Murphy, A.10
Chakravarty, S.11
Protter, A.12
Sehgal, P.B.13
Champion, H.C.14
Tuder, R.M.15
-
21
-
-
4544244944
-
Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats
-
Nagaoka T, Morio Y, Casanova N, Bauer N, Gebb S, McMurtry I, Oka M. Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats. Am J Physiol Lung Cell Mol Physiol. 2004;287:L665-L672.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.287
-
-
Nagaoka, T.1
Morio, Y.2
Casanova, N.3
Bauer, N.4
Gebb, S.5
McMurtry, I.6
Oka, M.7
-
22
-
-
34147189502
-
Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats
-
Oka M, Homma N, Taraseviciene-Stewart L, Morris KG, Kraskauskas D, Burns N, Voelkel NF, McMurtry IF. Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats. Circ Res. 2007;100:923-929.
-
(2007)
Circ Res
, vol.100
, pp. 923-929
-
-
Oka, M.1
Homma, N.2
Taraseviciene-Stewart, L.3
Morris, K.G.4
Kraskauskas, D.5
Burns, N.6
Voelkel, N.F.7
McMurtry, I.F.8
-
23
-
-
84867083335
-
Hemodynamic profile of severity at pulmonary vasoreactivity test in schistosomiasis patients
-
Japyassú FA, Mendes AA, Bandeira ÂP, Oliveira FR, Sobral Filho D. Hemodynamic profile of severity at pulmonary vasoreactivity test in schistosomiasis patients. Arq Bras Cardiol. 2012;99:789-796.
-
(2012)
Arq Bras Cardiol
, vol.99
, pp. 789-796
-
-
Japyassú, F.A.1
Mendes, A.A.2
Bandeira, Â.P.3
Oliveira, F.R.4
Sobral Filho, D.5
-
24
-
-
48749122568
-
Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression
-
Hoot KE, Lighthall J, Han G, Lu SL, Li A, Ju W, Kulesz-Martin M, Bottinger E, Wang XJ. Keratinocyte-specific Smad2 ablation results in increased epithelial-mesenchymal transition during skin cancer formation and progression. J Clin Invest. 2008;118:2722-2732.
-
(2008)
J Clin Invest
, vol.118
, pp. 2722-2732
-
-
Hoot, K.E.1
Lighthall, J.2
Han, G.3
Lu, S.L.4
Li, A.5
Ju, W.6
Kulesz-Martin, M.7
Bottinger, E.8
Wang, X.J.9
-
25
-
-
42249098277
-
Drug discovery: Schistosome treatment
-
Shadan S. Drug discovery: schistosome treatment. Nature. 2008;452:296.
-
(2008)
Nature
, vol.452
, pp. 296
-
-
Shadan, S.1
-
26
-
-
33745436655
-
Schistosomiasis and water resources development: Systematic review, meta-analysis, and estimates of people at risk
-
Steinmann P, Keiser J, Bos R, Tanner M, Utzinger J. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Lancet Infect Dis. 2006;6:411-425.
-
(2006)
Lancet Infect Dis
, vol.6
, pp. 411-425
-
-
Steinmann, P.1
Keiser, J.2
Bos, R.3
Tanner, M.4
Utzinger, J.5
-
27
-
-
77649198441
-
Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma
-
Oh CK, Geba GP, Molfino N. Investigational therapeutics targeting the IL-4/IL-13/STAT-6 pathway for the treatment of asthma. Eur Respir Rev. 2010;19:46-54.
-
(2010)
Eur Respir Rev
, vol.19
, pp. 46-54
-
-
Oh, C.K.1
Geba, G.P.2
Molfino, N.3
|