-
1
-
-
67649321877
-
Impact of serotonin 2c receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function
-
Abdallah L, Bonasera SJ, Hopf FW, O'Dell L, Giorgetti M, Jongsma M, Carra S, Pierucci M, Di Giovanni G, and Esposito E, et al. (2009) Impact of serotonin 2C receptor null mutation on physiology and behavior associated with nigrostriatal dopamine pathway function. J Neurosci 29:8156-8165
-
(2009)
J Neurosci
, vol.29
, pp. 8156-8165
-
-
Abdallah, L.1
Bonasera, S.J.2
Hopf, F.W.3
O'Dell, L.4
Giorgetti, M.5
Jongsma, M.6
Carra, S.7
Pierucci, M.8
Di Giovanni, G.9
Esposito, E.10
-
2
-
-
0031799667
-
Increased striatal dopamine transmission in schizophrenia: Confirmation in a second cohort
-
Abi-Dargham A, Gil R, Krystal J, Baldwin RM, Seibyl JP, Bowers M, van Dyck CH, Charney DS, Innis RB, and Laruelle M (1998) Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort. Am J Psychiatry 155:761-767
-
(1998)
Am J Psychiatry
, vol.155
, pp. 761-767
-
-
Abi-Dargham, A.1
Gil, R.2
Krystal, J.3
Baldwin, R.M.4
Seibyl, J.P.5
Bowers, M.6
Van Dyck, C.H.7
Charney, D.S.8
Innis, R.B.9
Laruelle, M.10
-
3
-
-
0034055690
-
Serotonin model of schizophrenia: Emerging role of glutamate mechanisms
-
Aghajanian GK and Marek GJ (2000) Serotonin model of schizophrenia: emerging role of glutamate mechanisms. Brain Res Brain Res Rev 31:302-312
-
(2000)
Brain Res Brain Res Rev
, vol.31
, pp. 302-312
-
-
Aghajanian, G.K.1
Marek, G.J.2
-
4
-
-
13844264398
-
Modulation of dopamine release by striatal 5-ht2c receptors
-
Alex KD, Yavanian GJ, McFarlane HG, Pluto CP, and Pehek EA (2005) Modulation of dopamine release by striatal 5-HT2C receptors. Synapse 55:242-251
-
(2005)
Synapse
, vol.55
, pp. 242-251
-
-
Alex, K.D.1
Yavanian, G.J.2
McFarlane, H.G.3
Pluto, C.P.4
Pehek, E.A.5
-
6
-
-
33745612043
-
Scientific and consumer models of recovery in schizophrenia: Concordance, contrasts, and implications
-
Bellack AS (2006) Scientific and consumer models of recovery in schizophrenia: concordance, contrasts, and implications. Schizophr Bull 32:432-442
-
(2006)
Schizophr Bull
, vol.32
, pp. 432-442
-
-
Bellack, A.S.1
-
7
-
-
67449138573
-
(1R, 3S)-(2-trans-PAT: A novel full-efficacy serotonin 5-HT2C receptor agonist with 5-HT2A and 5-HT2B receptor inverse agonist/antagonist activity
-
Booth RG, Fang L, Huang Y, Wilczynski A, and Sivendran S (2009) (1R, 3S)-(2)-trans-PAT: a novel full-efficacy serotonin 5-HT2C receptor agonist with 5-HT2A and 5-HT2B receptor inverse agonist/antagonist activity. Eur J Pharmacol 615: 1-9
-
(2009)
Eur J Pharmacol
, vol.615
, pp. 1-9
-
-
Booth, R.G.1
Fang, L.2
Huang, Y.3
Wilczynski, A.4
Sivendran, S.5
-
8
-
-
84889072831
-
Predictive validity of a mk-801-induced cognitive impairment model in mice: Implications on the potential limitations and challenges of modeling cognitive impairment associated with schizophrenia preclinically
-
Brown JW, Rueter LE, and Zhang M (2013) Predictive validity of a MK-801-induced cognitive impairment model in mice: implications on the potential limitations and challenges of modeling cognitive impairment associated with schizophrenia preclinically. Prog Neuropsychopharmacol Biol Psychiatry 49:53-62
-
(2013)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.49
, pp. 53-62
-
-
Brown, J.W.1
Rueter, L.E.2
Zhang, M.3
-
9
-
-
84876976859
-
Support for 5-ht2c receptor functional selectivity in vivo utilizing structurally diverse, selective 5-ht2c receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model
-
Canal CE, Booth RG, and Morgan D (2013) Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model. Neuropharmacology 70:112-121
-
(2013)
Neuropharmacology
, vol.70
, pp. 112-121
-
-
Canal, C.E.1
Booth, R.G.2
Morgan, D.3
-
10
-
-
0015861774
-
Relationship between the inhibition constant (k1) and the concentration of inhibitor which causes 50 per cent inhibition (i50) of an enzymatic reaction
-
Cheng Y and Prusoff WH (1973) Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol 22:3099-3108
-
(1973)
Biochem Pharmacol
, vol.22
, pp. 3099-3108
-
-
Cheng, Y.1
Prusoff, W.H.2
-
11
-
-
0029030343
-
Antipsychotic agents antagonize non-competitive n-methyl-d-Aspartate antagonist-induced behaviors
-
Corbett R, Camacho F, Woods AT, Kerman LL, Fishkin RJ, Brooks K, and Dunn RW (1995) Antipsychotic agents antagonize non-competitive N-methyl-D-Aspartate antagonist-induced behaviors. Psychopharmacology (Berl) 120:67-74
-
(1995)
Psychopharmacology (Berl)
, vol.120
, pp. 67-74
-
-
Corbett, R.1
Camacho, F.2
Woods, A.T.3
Kerman, L.L.4
Fishkin, R.J.5
Brooks, K.6
Dunn, R.W.7
-
12
-
-
84868322939
-
Glutamatergic synaptic dysregulation in schizophrenia: Therapeutic implications
-
DOI: 10.1007/978-3-642-25758-2-10
-
Coyle JT, Basu A, Benneyworth M, Balu D, and Konopaske G (2012) Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications. Handb Exp Pharmacol 213. 267-295 DOI: 10.1007/978-3-642-25758-2-10
-
(2012)
Handb Exp Pharmacol
, vol.213
, pp. 267-295
-
-
Coyle, J.T.1
Basu, A.2
Benneyworth, M.3
Balu, D.4
Konopaske, G.5
-
13
-
-
84866370991
-
Synergism between a serotonin 5-ht2a receptor (5-ht2ar) antagonist and 5-ht2cr agonist suggests new pharmacotherapeutics for cocaine addiction
-
CunninghamKA, AnastasioNC, FoxRG, Stutz SJ, Bubar MJ, Swinford SE,WatsonCS, Gilbertson SR, Rice KC, and Rosenzweig-Lipson S, et al. (2013) Synergism between a serotonin 5-HT2A receptor (5-HT2AR) antagonist and 5-HT2CR agonist suggests new pharmacotherapeutics for cocaine addiction. ACS Chem Neurosci 4:110-121
-
(2013)
ACS Chem Neurosci
, vol.4
, pp. 110-121
-
-
Cunningham, K.A.1
Anastasio, N.C.2
Fox, R.G.3
Stutz, S.J.4
Bubar, M.J.5
Swinford, S.E.6
Watson, C.S.7
Gilbertson, S.R.8
Rice, K.C.9
Rosenzweig-Lipson, S.10
-
15
-
-
1842610940
-
Constitutive activity of the serotonin2c receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens
-
De Deurwaerdére P, Navailles S, Berg KA, Clarke WP, and Spampinato U (2004) Constitutive activity of the serotonin2C receptor inhibits in vivo dopamine release in the rat striatum and nucleus accumbens. J Neurosci 24:3235-3241
-
(2004)
J Neurosci
, vol.24
, pp. 3235-3241
-
-
De Deurwaerdére, P.1
Navailles, S.2
Berg, K.A.3
Clarke, W.P.4
Spampinato, U.5
-
16
-
-
0033990419
-
Preferential modulation of mesolimbic vs. Nigrostriatal dopaminergic function by serotonin(2c/2b) receptor agonists: A combined in vivo electrophysiological and microdialysis study
-
Di Giovanni G, Di Matteo V, Di Mascio M, and Esposito E (2000) Preferential modulation of mesolimbic vs. nigrostriatal dopaminergic function by serotonin(2C/2B) receptor agonists: a combined in vivo electrophysiological and microdialysis study. Synapse 35:53-61
-
(2000)
Synapse
, vol.35
, pp. 53-61
-
-
Di Giovanni, G.1
Di Matteo, V.2
Di Mascio, M.3
Esposito, E.4
-
17
-
-
84874523496
-
The 5-ht2c receptor subtype controls central dopaminergic systems: Evidence from electrophysiological and neurochemical studies
-
(Di Giovanni G, Esposito E, and Di Matteo V, eds) , Humana Press, NewYork
-
Di Giovanni G, Esposito E, and Di Matteo V (2011) The 5-HT2C receptor subtype controls central dopaminergic systems: evidence from electrophysiological and neurochemical studies in 5-HT2C Receptors in the Pathophysiology of CNS Disease (Di Giovanni G, Esposito E, and Di Matteo V, eds) pp 215-247, Humana Press, NewYork
-
(2011)
5-HT2C Receptors in the Pathophysiology of CNS Disease
, pp. 215-247
-
-
Di Giovanni, G.1
Esposito, E.2
Di Matteo, V.3
-
18
-
-
1942519729
-
Selective stimulation of serotonin2c receptors blocks the enhancement of striatal and accumbal dopamine release induced by nicotine administration
-
Di Matteo V, Pierucci M, and Esposito E (2004) Selective stimulation of serotonin2c receptors blocks the enhancement of striatal and accumbal dopamine release induced by nicotine administration. J Neurochem 89:418-429
-
(2004)
J Neurochem
, vol.89
, pp. 418-429
-
-
Di Matteo, V.1
Pierucci, M.2
Esposito, E.3
-
19
-
-
20944441963
-
Way-163909 [(7br, 10ar)-1,2,3,4,8,9,10,10a-octahydro-7bh-cyclopenta-[b] [1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2c receptor-selective agonist with anorectic activity
-
Dunlop J, Sabb AL, Mazandarani H, Zhang J, Kalgaonker S, Shukhina E, Sukoff S, Vogel RL, Stack G, and Schechter L, et al. (2005) WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi] indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity. J Pharmacol Exp Ther 313:862-869
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 862-869
-
-
Dunlop, J.1
Sabb, A.L.2
Mazandarani, H.3
Zhang, J.4
Kalgaonker, S.5
Shukhina, E.6
Sukoff, S.7
Vogel, R.L.8
Stack, G.9
Schechter, L.10
-
20
-
-
67650680328
-
Characterizing the effects of 5-ht2c receptor ligands on motor activity and feeding behaviour in 5-ht2c receptor knockout mice
-
Fletcher PJ, Tampakeras M, Sinyard J, Slassi A, Isaac M, and Higgins GA (2009) Characterizing the effects of 5-HT2C receptor ligands on motor activity and feeding behaviour in 5-HT2C receptor knockout mice. Neuropharmacology 57:259-267
-
(2009)
Neuropharmacology
, vol.57
, pp. 259-267
-
-
Fletcher, P.J.1
Tampakeras, M.2
Sinyard, J.3
Slassi, A.4
Isaac, M.5
Higgins, G.A.6
-
21
-
-
0031023562
-
Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice
-
Gleason SD and Shannon HE (1997) Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice. Psychopharmacology (Berl) 129:79-84
-
(1997)
Psychopharmacology (Berl)
, vol.129
, pp. 79-84
-
-
Gleason, S.D.1
Shannon, H.E.2
-
22
-
-
0021646446
-
Evidence for 5-ht2 involvement in the mechanism of action of hallucinogenic agents
-
Glennon RA, Titeler M, and McKenney JD (1984) Evidence for 5-HT2 involvement in the mechanism of action of hallucinogenic agents. Life Sci 35:2505-2511
-
(1984)
Life Sci
, vol.35
, pp. 2505-2511
-
-
Glennon, R.A.1
Titeler, M.2
McKenney, J.D.3
-
24
-
-
67449135879
-
5-HT2A and 5-HT2C receptors exert opposing effects on locomotor activity in mice
-
Halberstadt AL, van der Heijden I, Ruderman MA, Risbrough VB, Gingrich JA, Geyer MA, and Powell SB (2009) 5-HT2A and 5-HT2C receptors exert opposing effects on locomotor activity in mice. Neuropsychopharmacology 34:1958-1967
-
(2009)
Neuropsychopharmacology
, vol.34
, pp. 1958-1967
-
-
Halberstadt, A.L.1
Van Der Heijden, I.2
Ruderman, M.A.3
Risbrough, V.B.4
Gingrich, J.A.5
Geyer, M.A.6
Powell, S.B.7
-
25
-
-
84858332463
-
The 5-ht2c receptor agonist lorcaserin reduces nicotine self-Administration, discrimination, and reinstatement: Relationship to feeding behavior and impulse control
-
Higgins GA, Silenieks LB, Rossmann A, Rizos Z, Noble K, Soko AD, and Fletcher PJ (2012) The 5-HT2C receptor agonist lorcaserin reduces nicotine self-Administration, discrimination, and reinstatement: relationship to feeding behavior and impulse control. Neuropsychopharmacology 37:1177-1191
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 1177-1191
-
-
Higgins, G.A.1
Silenieks, L.B.2
Rossmann, A.3
Rizos, Z.4
Noble, K.5
Soko, A.D.6
Fletcher, P.J.7
-
26
-
-
67651154609
-
Overexpression of 5-ht2c receptors in forebrain leads to elevated anxiety and hypoactivity
-
Kimura A, Stevenson PL, Carter RN, Maccoll G, French KL, Simons JP, Al-Shawi R, Kelly V, Chapman KE, and Holmes MC (2009) Overexpression of 5-HT2C receptors in forebrain leads to elevated anxiety and hypoactivity. Eur J Neurosci 30:299-306
-
(2009)
Eur J Neurosci
, vol.30
, pp. 299-306
-
-
Kimura, A.1
Stevenson, P.L.2
Carter, R.N.3
Maccoll, G.4
French, K.L.5
Simons, J.P.6
Al-Shawi, R.7
Kelly, V.8
Chapman, K.E.9
Holmes, M.C.10
-
27
-
-
40849135860
-
Serotonin 5-ht2c receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors
-
Lam DD, Przydzial MJ, Ridley SH, Yeo GS, Rochford JJ, O'Rahilly S, and Heisler LK (2007) Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors. Endocrinology 149:1323-1328
-
(2007)
Endocrinology
, vol.149
, pp. 1323-1328
-
-
Lam, D.D.1
Przydzial, M.J.2
Ridley, S.H.3
Yeo, G.S.4
Rochford, J.J.5
O'Rahilly, S.6
Heisler, L.K.7
-
28
-
-
84884161208
-
Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: A multiple-treatments meta-Analysis
-
Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, Samara M, Barbui C, Engel RR, and Geddes JR, et al. (2013) Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-Analysis. Lancet 382:951-962
-
(2013)
Lancet
, vol.382
, pp. 951-962
-
-
Leucht, S.1
Cipriani, A.2
Spineli, L.3
Mavridis, D.4
Orey, D.5
Richter, F.6
Samara, M.7
Barbui, C.8
Engel, R.R.9
Geddes, J.R.10
-
29
-
-
25144456112
-
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
-
Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Investigators
-
Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, Keefe RS, Davis SM, Davis CE, and Lebowitz BD, et al.; Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Investigators (2005) Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med 353: 1209-1223
-
(2005)
N Engl J Med
, vol.353
, pp. 1209-1223
-
-
Lieberman, J.A.1
Stroup, T.S.2
McEvoy, J.P.3
Swartz, M.S.4
Rosenheck, R.A.5
Perkins, D.O.6
Keefe, R.S.7
Davis, S.M.8
Davis, C.E.9
Lebowitz, B.D.10
-
30
-
-
0033804148
-
Treatment refractory schizophrenia
-
Lindenmayer J-P (2000) Treatment refractory schizophrenia. Psychiatr Q 71: 373-384
-
(2000)
Psychiatr Q
, vol.71
, pp. 373-384
-
-
Lindenmayer, J.-P.1
-
31
-
-
0034867499
-
Regional distribution and cellular localization of 5-ht2c receptor mrna in monkey brain: Comparison with [3h]mesulergine binding sites and choline acetyltransferase mrna
-
López-Giménez JF, Mengod G, Palacios JM, and Vilaró MT (2001) Regional distribution and cellular localization of 5-HT2C receptor mRNA in monkey brain: comparison with [3H]mesulergine binding sites and choline acetyltransferase mRNA. Synapse 42:12-26
-
(2001)
Synapse
, vol.42
, pp. 12-26
-
-
López-Giménez, J.F.1
Mengod, G.2
Palacios, J.M.3
Vilaró, M.T.4
-
32
-
-
33845876953
-
Way-163909 [(7br,10ar)-1,2,3,4,8,9,10,10a-octahydro-7bh-cyclopenta-[b][1, 4]diazepino[6,7,1hi] indole]: A novel 5-hydroxytryptamine 2c receptor-selective agonist with preclinical antipsychotic-like activity
-
Marquis KL, Sabb AL, Logue SF, Brennan JA, Piesla MJ, Comery TA, Grauer SM, Ashby CR, Jr., Nguyen HQ, and Dawson LA, et al. (2007) WAY-163909 [(7bR,10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7, 1hi] indole]: A novel 5-hydroxytryptamine 2C receptor-selective agonist with preclinical antipsychotic-like activity. J Pharmacol Exp Ther 320:486-496
-
(2007)
J Pharmacol Exp Ther
, vol.320
, pp. 486-496
-
-
Marquis, K.L.1
Sabb, A.L.2
Logue, S.F.3
Brennan, J.A.4
Piesla, M.J.5
Comery, T.A.6
Grauer, S.M.7
Ashby, C.R.8
Jr. Nguyen, H.Q.9
Dawson, L.A.10
-
33
-
-
84874887231
-
Dopamine neurotransmission and atypical antipsychotics in prefrontal cortex: A critical review
-
Masana M, Santana N, Artigas F, and Bortolozzi A (2012) Dopamine neurotransmission and atypical antipsychotics in prefrontal cortex: a critical review. Curr Top Med Chem 12:2357-2374
-
(2012)
Curr Top Med Chem
, vol.12
, pp. 2357-2374
-
-
Masana, M.1
Santana, N.2
Artigas, F.3
Bortolozzi, A.4
-
34
-
-
0024722805
-
5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system
-
Molineaux SM, Jessell TM, Axel R, and Julius D (1989) 5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system. Proc Natl Acad Sci USA 86:6793-6797
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 6793-6797
-
-
Molineaux, S.M.1
Jessell, T.M.2
Axel, R.3
Julius, D.4
-
35
-
-
84884885665
-
Molecular and behavioral pharmacology of two novel orallyactive 5ht2 modulators: Potential utility as antipsychotic medications
-
Morgan D, Kondabolu K, Kuipers A, Sakhuja R, Robertson KL, Rowland NE, and Booth RG (2013) Molecular and behavioral pharmacology of two novel orallyactive 5HT2 modulators: potential utility as antipsychotic medications. Neuropharmacology 72:274-281
-
(2013)
Neuropharmacology
, vol.72
, pp. 274-281
-
-
Morgan, D.1
Kondabolu, K.2
Kuipers, A.3
Sakhuja, R.4
Robertson, K.L.5
Rowland, N.E.6
Booth, R.G.7
-
36
-
-
84884839760
-
Assessment of subjective cognitive and emotional effects of antipsychotic drugs
-
Moritz S, Andreou C, Klingberg S, Thoering T, and Peters MJ (2013) Assessment of subjective cognitive and emotional effects of antipsychotic drugs. Effect by defect? Neuropharmacology 72:179-186
-
(2013)
Effect by defect? Neuropharmacology
, vol.72
, pp. 179-186
-
-
Moritz, S.1
Andreou, C.2
Klingberg, S.3
Thoering, T.4
Peters, M.J.5
-
38
-
-
79955607526
-
Serotonin 5-ht2a receptor function as a contributing factor to both neuropsychiatric and cardiovascular diseases
-
Nichols CD (2009) Serotonin 5-HT2A receptor function as a contributing factor to both neuropsychiatric and cardiovascular diseases. Cardiovasc Psychiatry Neurol 2009: 475108
-
(2009)
Cardiovasc Psychiatry Neurol
, vol.2009
, pp. 475108
-
-
Nichols, C.D.1
-
39
-
-
84898781378
-
-
National Institute of Mental Health (NIMH) Bethesda,MD
-
National Institute of Mental Health (NIMH) 2010) Mental Health Medications, U.S. Department of Health and Human Services, Bethesda,MD. http://www.nimh.nih.gov/health/publications/mental-health-medications/ nimh-mental-health-medications.pdf
-
(2010)
Mental Health Medications, U.S. Department of Health and Human Services
-
-
-
40
-
-
84892526188
-
Impact of rna editing on functions of the serotonin 2c receptor in vivo
-
Olaghere da Silva UB, Morabito MV, Canal CE, Airey DC, Emeson RB, and Sanders-Bush E 2010) Impact of RNA editing on functions of the serotonin 2C receptor in vivo. Front Neurosci 4 1-10
-
(2010)
Front Neurosci
, vol.4
, pp. 1-10
-
-
Olaghere Da Silva, U.B.1
Morabito, M.V.2
Canal, C.E.3
Airey, D.C.4
Emeson, R.B.5
Sanders-Bush, E.6
-
41
-
-
1242283872
-
5-HT2 receptors differentially modulate dopamine-mediated auto-inhibition in A9 and A10 midbrain areas of the rat
-
Olijslagers JE, Werkman TR, McCreary AC, Siarey R, Kruse CG, and Wadman WJ (2004) 5-HT2 receptors differentially modulate dopamine-mediated auto-inhibition in A9 and A10 midbrain areas of the rat. Neuropharmacology 46:504-510
-
(2004)
Neuropharmacology
, vol.46
, pp. 504-510
-
-
Olijslagers, J.E.1
Werkman, T.R.2
McCreary, A.C.3
Siarey, R.4
Kruse, C.G.5
Wadman, W.J.6
-
42
-
-
33646535647
-
Regional distribution and relative abundance of serotonin(2c) receptors in human brain: Effect of suicide
-
Pandey GN, Dwivedi Y, Ren X, Rizavi HS, Faludi G, Sarosi A, and Palkovits M (2006) Regional distribution and relative abundance of serotonin(2c) receptors in human brain: effect of suicide. Neurochem Res 31:167-176
-
(2006)
Neurochem Res
, vol.31
, pp. 167-176
-
-
Pandey, G.N.1
Dwivedi, Y.2
Ren, X.3
Rizavi, H.S.4
Faludi, G.5
Sarosi, A.6
Palkovits, M.7
-
43
-
-
33845987107
-
Lifetime prevalence of psychotic and bipolar i disorders in a general population
-
Perälä J, Suvisaari J, Saarni SI, Kuoppasalmi K, Isometsä E, Pirkola S, Partonen T, Tuulio-Henriksson A, Hintikka J, and Kieseppä T, et al. (2007) Lifetime prevalence of psychotic and bipolar I disorders in a general population. Arch Gen Psychiatry 64:19-28
-
(2007)
Arch Gen Psychiatry
, vol.64
, pp. 19-28
-
-
Perälä, J.1
Suvisaari, J.2
Saarni, S.I.3
Kuoppasalmi, K.4
Isometsä, E.5
Pirkola, S.6
Partonen, T.7
Tuulio-Henriksson, A.8
Hintikka, J.9
Kieseppä, T.10
-
45
-
-
33845736382
-
Role of atypical opiates in ocd. Experimental approach through the study of 5-ht2a/c receptor-mediated behavior
-
Rojas-Corrales MO, Gibert-Rahola J, and Mico JA (2007) Role of atypical opiates in OCD. Experimental approach through the study of 5-HT2A/C receptor-mediated behavior. Psychopharmacology (Berl) 190:221-231
-
(2007)
Psychopharmacology (Berl)
, vol.190
, pp. 221-231
-
-
Rojas-Corrales, M.O.1
Gibert-Rahola, J.2
Mico, J.A.3
-
46
-
-
84868305215
-
5-HT2C Agonists as Therapeutics for the Treatment of Schizophrenia
-
(Geyer MA and Gross G, eds) Springer, New York
-
Rosenzweig-Lipson S, Comery TA, Marquis KL, Gross J, and Dunlop J (2012) 5-HT2C Agonists as Therapeutics for the Treatment of Schizophrenia, in Novel Antischizophrenia Treatments (Geyer MA and Gross G, eds) pp 147-165, Springer, New York
-
(2012)
Novel Antischizophrenia Treatments
, pp. 147-165
-
-
Rosenzweig-Lipson, S.1
Comery, T.A.2
Marquis, K.L.3
Gross, J.4
Dunlop, J.5
-
47
-
-
67649379367
-
Serotonergic drugs and valvular heart disease
-
Rothman RB and Baumann MH (2009) Serotonergic drugs and valvular heart disease. Expert Opin Drug Saf 8:317-329
-
(2009)
Expert Opin Drug Saf
, vol.8
, pp. 317-329
-
-
Rothman, R.B.1
Baumann, M.H.2
-
49
-
-
84898780067
-
-
ACNP, Waikoloa Beach, HI
-
Shen J, Zhao Y, Rosenzweig-Lipson S, Popp D, Williams J, Giller E, Detke M, and Kane J (2010) A 6-Week Randomized, Double-Blind, Placebo-controlled, Comparator Referenced, Multicenter Trial of Vabicaserin in Subjects with Acute Exacerbation of Schizophrenia, ACNP, Waikoloa Beach, HI
-
(2010)
A 6-Week Randomized, Double-Blind, Placebo-controlled, Comparator Referenced, Multicenter Trial of Vabicaserin in Subjects with Acute Exacerbation of Schizophrenia
-
-
Shen, J.1
Zhao, Y.2
Rosenzweig-Lipson, S.3
Popp, D.4
Williams, J.5
Giller, E.6
Detke, M.7
Kane, J.8
-
50
-
-
79955473823
-
Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia
-
Simpson EH, Kellendonk C, Ward RD, Richards V, Lipatova O, Fairhurst S, Kandel ER, and Balsam PD (2011) Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia. Biol Psychiatry 69: 928-935
-
(2011)
Biol Psychiatry
, vol.69
, pp. 928-935
-
-
Simpson, E.H.1
Kellendonk, C.2
Ward, R.D.3
Richards, V.4
Lipatova, O.5
Fairhurst, S.6
Kandel, E.R.7
Balsam, P.D.8
-
51
-
-
33846327871
-
Cp-809,101, a selective 5-ht2c agonist, shows activity in animal models of antipsychotic activity
-
Siuciak JA, Chapin DS, McCarthy SA, Guanowsky V, Brown J, Chiang P, Marala R, Patterson T, Seymour PA, and Swick A, et al. (2007) CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity. Neuropharmacology 52:279-290
-
(2007)
Neuropharmacology
, vol.52
, pp. 279-290
-
-
Siuciak, J.A.1
Chapin, D.S.2
McCarthy, S.A.3
Guanowsky, V.4
Brown, J.5
Chiang, P.6
Marala, R.7
Patterson, T.8
Seymour, P.A.9
Swick, A.10
-
52
-
-
77954635020
-
Multicenter, placebocontrolled trial of lorcaserin for weight management
-
Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM) Study Group
-
Smith SR, Weissman NJ, Anderson CM, Sanchez M, Chuang E, Stubbe S, Bays H, and Shanahan WR; Behavioral Modification and Lorcaserin for Overweight and Obesity Management (BLOOM) Study Group (2010) Multicenter, placebocontrolled trial of lorcaserin for weight management. N Engl J Med 363:245-256
-
(2010)
N Engl J Med
, vol.363
, pp. 245-256
-
-
Smith, S.R.1
Weissman, N.J.2
Anderson, C.M.3
Sanchez, M.4
Chuang, E.5
Stubbe, S.6
Bays, H.7
Shanahan, W.R.8
-
53
-
-
84865527858
-
Neural changes associated with appetite information processing in schizophrenic patients after 16 weeks of olanzapine treatment
-
Stip E, Lungu OV, Anselmo K, Letourneau G, Mendrek A, Stip B, Lipp O, Lalonde P, and Bentaleb LA (2012) Neural changes associated with appetite information processing in schizophrenic patients after 16 weeks of olanzapine treatment. Transl Psychiatry 2:e128
-
(2012)
Transl Psychiatry
, vol.2
-
-
Stip, E.1
Lungu, O.V.2
Anselmo, K.3
Letourneau, G.4
Mendrek, A.5
Stip, B.6
Lipp, O.7
Lalonde, P.8
Bentaleb, L.A.9
-
54
-
-
44549087928
-
Antipsychotic drug action: Antagonism, inverse agonism or partial agonism
-
Strange PG (2008) Antipsychotic drug action: antagonism, inverse agonism or partial agonism. Trends Pharmacol Sci 29:314-321
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 314-321
-
-
Strange, P.G.1
-
55
-
-
42449134961
-
Lorcaserin, a novel selective human 5-hydroxytryptamine2c agonist: In vitro and in vivo pharmacological characterization
-
Thomsen WJ, Grottick AJ, Menzaghi F, Reyes-Saldana H, Espitia S, Yuskin D, Whelan K, Martin M, Morgan M, and Chen W, et al. (2008) Lorcaserin, a novel selective human 5-hydroxytryptamine2C agonist: in vitro and in vivo pharmacological characterization. J Pharmacol Exp Ther 325:577-587
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 577-587
-
-
Thomsen, W.J.1
Grottick, A.J.2
Menzaghi, F.3
Reyes-Saldana, H.4
Espitia, S.5
Yuskin, D.6
Whelan, K.7
Martin, M.8
Morgan, M.9
Chen, W.10
-
56
-
-
4243182599
-
Pharmacological characterization of ac-90179 [2-(4-methoxyphenyl)-n-(4- methyl-benzyl)-n-(1-methyl-piperidin-4-yl)-Acetamide hydrochloride]: A selective serotonin 2a receptor inverse agonist
-
Vanover KE, Harvey SC, Son T, Bradley SR, Kold H, Makhay M, Veinbergs I, Spalding TA, Weiner DM, and Andersson CM, et al. (2004) Pharmacological characterization of AC-90179 [2-(4-methoxyphenyl)-N-(4-methyl-benzyl)-N-(1- methyl-piperidin-4-yl)-Acetamide hydrochloride]: a selective serotonin 2A receptor inverse agonist. J Pharmacol Exp Ther 310:943-951
-
(2004)
J Pharmacol Exp Ther
, vol.310
, pp. 943-951
-
-
Vanover, K.E.1
Harvey, S.C.2
Son, T.3
Bradley, S.R.4
Kold, H.5
Makhay, M.6
Veinbergs, I.7
Spalding, T.A.8
Weiner, D.M.9
Andersson, C.M.10
-
57
-
-
67650499136
-
New approach to 4-phenyl-b-Aminotetralin from 4-(3-halophenyl)tetralen-2- ol phenylacetate
-
Vincek AS and Booth RG (2009) New approach to 4-phenyl-b-Aminotetralin from 4-(3-halophenyl)tetralen-2-ol phenylacetate. Tetrahedron Lett 50:5107-5109
-
(2009)
Tetrahedron Lett
, vol.50
, pp. 5107-5109
-
-
Vincek, A.S.1
Booth, R.G.2
-
58
-
-
84865250097
-
Reduced levels of serotonin 2a receptors underlie resistance of egr3-deficient mice to locomotor suppression by clozapine
-
Williams AA, Ingram WM, Levine S, Resnik J, Kamel CM, Lish JR, Elizalde DI, Janowski SA, Shoker J, and Kozlenkov A, et al. (2012) Reduced levels of serotonin 2A receptors underlie resistance of Egr3-deficient mice to locomotor suppression by clozapine. Neuropsychopharmacology 37:2285-2298
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 2285-2298
-
-
Williams, A.A.1
Ingram, W.M.2
Levine, S.3
Resnik, J.4
Kamel, C.M.5
Lish, J.R.6
Elizalde, D.I.7
Janowski, S.A.8
Shoker, J.9
Kozlenkov, A.10
-
59
-
-
56349145180
-
5-HT2CRs expressed by proopiomelanocortin neurons regulate energy homeostasis
-
Xu Y, Jones JE, Kohno D, Williams KW, Lee CE, Choi MJ, Anderson JG, Heisler LK, Zigman JM, and Lowell BB, et al. (2008) 5-HT2CRs expressed by proopiomelanocortin neurons regulate energy homeostasis. Neuron 60:582-589
-
(2008)
Neuron
, vol.60
, pp. 582-589
-
-
Xu, Y.1
Jones, J.E.2
Kohno, D.3
Williams, K.W.4
Lee, C.E.5
Choi, M.J.6
Anderson, J.G.7
Heisler, L.K.8
Zigman, J.M.9
Lowell, B.B.10
-
60
-
-
30444450710
-
Distinct functional profiles of aripiprazole and olanzapine at rna edited human 5-ht2c receptor isoforms
-
Zhang JY, Kowal DM, Nawoschik SP, Lou Z, and Dunlop J (2006) Distinct functional profiles of aripiprazole and olanzapine at RNA edited human 5-HT2C receptor isoforms. Biochem Pharmacol 71:521-529.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 521-529
-
-
Zhang, J.Y.1
Kowal, D.M.2
Nawoschik, S.P.3
Lou, Z.4
Dunlop, J.5
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