-
1
-
-
0029787944
-
Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects
-
Laruelle M., et al. Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proc. Natl Acad. Sci. U. S. A. 93 (1996) 9235-9240
-
(1996)
Proc. Natl Acad. Sci. U. S. A.
, vol.93
, pp. 9235-9240
-
-
Laruelle, M.1
-
2
-
-
0034608753
-
Increased baseline occupancy of D2 receptors by dopamine in schizophrenia
-
Abi-Dargham A., et al. Increased baseline occupancy of D2 receptors by dopamine in schizophrenia. Proc. Natl Acad. Sci. U. S. A. 97 (2000) 8104-8109
-
(2000)
Proc. Natl Acad. Sci. U. S. A.
, vol.97
, pp. 8104-8109
-
-
Abi-Dargham, A.1
-
3
-
-
11844286960
-
Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies
-
Abi-Dargham A., and Laruelle M. Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies. Eur. Psychiatry 20 (2005) 15-27
-
(2005)
Eur. Psychiatry
, vol.20
, pp. 15-27
-
-
Abi-Dargham, A.1
Laruelle, M.2
-
4
-
-
0141788413
-
Prefrontal DA transmission at D1 receptors and the pathology of schizophrenia
-
Abi-Dargham A., and Moore H. Prefrontal DA transmission at D1 receptors and the pathology of schizophrenia. Neuroscientist 9 (2003) 404-416
-
(2003)
Neuroscientist
, vol.9
, pp. 404-416
-
-
Abi-Dargham, A.1
Moore, H.2
-
6
-
-
33749321169
-
Randomized controlled trial of the effect on quality of life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
-
Jones P.B., et al. Randomized controlled trial of the effect on quality of life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1). Arch. Gen. Psychiatry 63 (2006) 1079-1087
-
(2006)
Arch. Gen. Psychiatry
, vol.63
, pp. 1079-1087
-
-
Jones, P.B.1
-
7
-
-
25144456112
-
Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
-
Lieberman J.A., et al. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N. Engl. J. Med. 353 (2005) 1209-1223
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 1209-1223
-
-
Lieberman, J.A.1
-
8
-
-
0035101404
-
Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects
-
Strange P.G. Antipsychotic drugs: importance of dopamine receptors for mechanisms of therapeutic actions and side effects. Pharmacol. Rev. 53 (2001) 119-133
-
(2001)
Pharmacol. Rev.
, vol.53
, pp. 119-133
-
-
Strange, P.G.1
-
9
-
-
8244235137
-
3 receptor antagonist with both presynaptic and limbic selectivity
-
3 receptor antagonist with both presynaptic and limbic selectivity. J. Pharmacol. Exp. Ther. 280 (1997) 83-97
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.280
, pp. 83-97
-
-
Schoemaker, H.1
-
10
-
-
0024466603
-
Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values
-
Meltzer H.Y., et al. Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values. J. Pharmacol. Exp. Ther. 251 (1989) 238-246
-
(1989)
J. Pharmacol. Exp. Ther.
, vol.251
, pp. 238-246
-
-
Meltzer, H.Y.1
-
11
-
-
0033696731
-
Improving the treatment of schizophrenia: focus on serotonin (5-HT)(1A) receptors
-
Millan M.J. Improving the treatment of schizophrenia: focus on serotonin (5-HT)(1A) receptors. J. Pharmacol. Exp. Ther. 295 (2000) 853-861
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.295
, pp. 853-861
-
-
Millan, M.J.1
-
12
-
-
0030909322
-
Perspectives on the role of serotonergic mechanisms in the pharmacology of schizophrenia
-
Busatto G.F., and Kerwin R.W. Perspectives on the role of serotonergic mechanisms in the pharmacology of schizophrenia. J. Psychopharmacol. 11 (1997) 3-12
-
(1997)
J. Psychopharmacol.
, vol.11
, pp. 3-12
-
-
Busatto, G.F.1
Kerwin, R.W.2
-
13
-
-
0035028512
-
Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence
-
Carlsson A., et al. Interactions between monoamines, glutamate, and GABA in schizophrenia: new evidence. Annu. Rev. Pharmacol. Toxicol. 41 (2001) 237-260
-
(2001)
Annu. Rev. Pharmacol. Toxicol.
, vol.41
, pp. 237-260
-
-
Carlsson, A.1
-
14
-
-
4344714861
-
Aripiprazole: a review of its use in schizophrenia and schizoaffective disorder
-
Swainston Harrison T., and Perry C.M. Aripiprazole: a review of its use in schizophrenia and schizoaffective disorder. Drugs 64 (2004) 1715-1736
-
(2004)
Drugs
, vol.64
, pp. 1715-1736
-
-
Swainston Harrison, T.1
Perry, C.M.2
-
15
-
-
33747173804
-
Aripiprazole for schizophrenia. Systematic review
-
El-Sayeh H.G., et al. Aripiprazole for schizophrenia. Systematic review. Br. J. Psychiatry 189 (2006) 102-108
-
(2006)
Br. J. Psychiatry
, vol.189
, pp. 102-108
-
-
El-Sayeh, H.G.1
-
16
-
-
0031593972
-
Effects of the D3 and autoreceptor-preferring dopamine antagonist (+)-UH232 in schizophrenia
-
Lahti A.C., et al. Effects of the D3 and autoreceptor-preferring dopamine antagonist (+)-UH232 in schizophrenia. J. Neural Transm. 105 (1998) 719-734
-
(1998)
J. Neural Transm.
, vol.105
, pp. 719-734
-
-
Lahti, A.C.1
-
17
-
-
0031963973
-
Antipsychotic properties of the partial dopamine agonist (-)-3-(3-hydroxyphenyl)-N-n-propylpiperidine(preclamol) in schizophrenia
-
Lahti A.C., et al. Antipsychotic properties of the partial dopamine agonist (-)-3-(3-hydroxyphenyl)-N-n-propylpiperidine(preclamol) in schizophrenia. Biol. Psychiatry 43 (1998) 2-11
-
(1998)
Biol. Psychiatry
, vol.43
, pp. 2-11
-
-
Lahti, A.C.1
-
18
-
-
33750473056
-
2 receptor partial agonist
-
2 receptor partial agonist. Eur. J. Pharmacol. 552 (2006) 36-45
-
(2006)
Eur. J. Pharmacol.
, vol.552
, pp. 36-45
-
-
Heinrich, J.N.1
-
19
-
-
33645451501
-
Partial agonist properties of the antipsychotics SSR181507, aripiprazole and bifeprunox at dopamine D2 receptors: G protein activation and prolactin release
-
Cosi C., et al. Partial agonist properties of the antipsychotics SSR181507, aripiprazole and bifeprunox at dopamine D2 receptors: G protein activation and prolactin release. Eur. J. Pharmacol. 535 (2006) 135-144
-
(2006)
Eur. J. Pharmacol.
, vol.535
, pp. 135-144
-
-
Cosi, C.1
-
20
-
-
41849132178
-
Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors
-
Strange P.G. Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors. Br. J. Pharmacol. 153 (2008) 1353-1363
-
(2008)
Br. J. Pharmacol.
, vol.153
, pp. 1353-1363
-
-
Strange, P.G.1
-
22
-
-
0034018856
-
Characterization of dopaminergic compounds at hD2short, hD4.2 and hD4.7 receptors in agonist-stimulated [35S]GTPγS binding assays
-
Gilliland S.L., and Alper R.H. Characterization of dopaminergic compounds at hD2short, hD4.2 and hD4.7 receptors in agonist-stimulated [35S]GTPγS binding assays. Naunyn Schmiedebergs Arch. Pharmacol. 361 (2000) 498-504
-
(2000)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.361
, pp. 498-504
-
-
Gilliland, S.L.1
Alper, R.H.2
-
23
-
-
0037864223
-
Pharmacological analysis of a dopamine D(2Short):G(αo) fusion protein expressed in Sf9 cells
-
Gazi L., et al. Pharmacological analysis of a dopamine D(2Short):G(αo) fusion protein expressed in Sf9 cells. FEBS Lett. 545 (2003) 155-160
-
(2003)
FEBS Lett.
, vol.545
, pp. 155-160
-
-
Gazi, L.1
-
24
-
-
0032194951
-
Selective activation of Gαo by D2L dopamine receptors in NS20Y neuroblastoma cells
-
Watts V.J., et al. Selective activation of Gαo by D2L dopamine receptors in NS20Y neuroblastoma cells. J. Neurosci. 18 (1998) 8692-8699
-
(1998)
J. Neurosci.
, vol.18
, pp. 8692-8699
-
-
Watts, V.J.1
-
28
-
-
0035051547
-
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation
-
Wilson J., et al. Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation. J. Neurochem. 77 (2001) 493-504
-
(2001)
J. Neurochem.
, vol.77
, pp. 493-504
-
-
Wilson, J.1
-
30
-
-
0037214555
-
2/alpha 1B receptor to the phospholipase C pathway: inverse agonism to silent antagonism by neuroleptic drugs
-
2/alpha 1B receptor to the phospholipase C pathway: inverse agonism to silent antagonism by neuroleptic drugs. J. Pharmacol. Exp. Ther. 304 (2003) 380-390
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.304
, pp. 380-390
-
-
Wurch, T.1
-
33
-
-
33845903110
-
Functional selectivity and classical concepts of quantitative pharmacology
-
Urban J.D., et al. Functional selectivity and classical concepts of quantitative pharmacology. J. Pharmacol. Exp. Ther. 320 (2006) 1-13
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.320
, pp. 1-13
-
-
Urban, J.D.1
-
34
-
-
0022921561
-
(+)-AJ 76 and (+)-UH 232: central stimulants acting as preferential dopamine autoreceptor antagonists
-
Svensson K., et al. (+)-AJ 76 and (+)-UH 232: central stimulants acting as preferential dopamine autoreceptor antagonists. Naunyn Schmiedebergs Arch. Pharmacol. 334 (1986) 234-245
-
(1986)
Naunyn Schmiedebergs Arch. Pharmacol.
, vol.334
, pp. 234-245
-
-
Svensson, K.1
-
35
-
-
0032773336
-
4.4 receptors expressed in Chinese hamster ovary cells
-
4.4 receptors expressed in Chinese hamster ovary cells. Br. J. Pharmacol. 127 (1999) 1135-1144
-
(1999)
Br. J. Pharmacol.
, vol.127
, pp. 1135-1144
-
-
Coldwell, M.C.1
-
36
-
-
33749027768
-
Assays for enhanced activity of low efficacy partial agonists at the D(2) dopamine receptor
-
Lin H., et al. Assays for enhanced activity of low efficacy partial agonists at the D(2) dopamine receptor. Br. J. Pharmacol. 149 (2006) 291-299
-
(2006)
Br. J. Pharmacol.
, vol.149
, pp. 291-299
-
-
Lin, H.1
-
37
-
-
0020602994
-
Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP
-
Hjorth S., et al. Central dopamine receptor agonist and antagonist actions of the enantiomers of 3-PPP. Psychopharmacology (Berl.) 81 (1983) 89-99
-
(1983)
Psychopharmacology (Berl.)
, vol.81
, pp. 89-99
-
-
Hjorth, S.1
-
38
-
-
0023265884
-
Relationship between receptor occupancy and response at striatal dopamine autoreceptors
-
Meller E., et al. Relationship between receptor occupancy and response at striatal dopamine autoreceptors. Mol. Pharmacol. 31 (1987) 592-598
-
(1987)
Mol. Pharmacol.
, vol.31
, pp. 592-598
-
-
Meller, E.1
-
39
-
-
0029023002
-
2 receptor antagonistic activity
-
2 receptor antagonistic activity. J. Pharmacol. Exp. Ther. 274 (1995) 329-336
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.274
, pp. 329-336
-
-
Kikuchi, T.1
-
40
-
-
0031465316
-
Inverse agonism and the regulation of receptor number
-
Milligan G., and Bond R.A. Inverse agonism and the regulation of receptor number. Trends Pharmacol. Sci. 18 (1997) 468-474
-
(1997)
Trends Pharmacol. Sci.
, vol.18
, pp. 468-474
-
-
Milligan, G.1
Bond, R.A.2
-
41
-
-
0031577960
-
2 receptor following repeated treatment in the rat striatum
-
2 receptor following repeated treatment in the rat striatum. Eur. J. Pharmacol. 321 (1997) 105-111
-
(1997)
Eur. J. Pharmacol.
, vol.321
, pp. 105-111
-
-
Inoue, A.1
-
42
-
-
0032052732
-
2 dopamine receptor and prolactin gene expression by haloperidol and aripiprazole in the rat pituitary
-
2 dopamine receptor and prolactin gene expression by haloperidol and aripiprazole in the rat pituitary. Brain Res. Mol. Brain Res. 55 (1998) 285-292
-
(1998)
Brain Res. Mol. Brain Res.
, vol.55
, pp. 285-292
-
-
Inoue, A.1
-
43
-
-
33748419500
-
2 receptor, but the rodent metabolite displays antagonist properties
-
2 receptor, but the rodent metabolite displays antagonist properties. Eur. J. Pharmacol. 546 (2006) 88-94
-
(2006)
Eur. J. Pharmacol.
, vol.546
, pp. 88-94
-
-
Wood, M.D.1
-
44
-
-
34347336444
-
Neuropharmacological profile of bifeprunox: merits and limitations in comparison with other third-generation antipsychotics
-
Newman-Tancredi A., et al. Neuropharmacological profile of bifeprunox: merits and limitations in comparison with other third-generation antipsychotics. Curr. Opin. Investig. Drugs 8 (2007) 539-554
-
(2007)
Curr. Opin. Investig. Drugs
, vol.8
, pp. 539-554
-
-
Newman-Tancredi, A.1
-
45
-
-
33845718611
-
2 receptor-mediated signaling pathways
-
2 receptor-mediated signaling pathways. Neuropsychopharmacology 32 (2007) 67-77
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 67-77
-
-
Urban, J.D.1
-
46
-
-
34247507644
-
2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1, Gi2 and Gi3
-
2 receptor: (S)-3-(3-hydroxyphenyl)-N-propylpiperidine is an agonist for activation of Go1 but an antagonist/inverse agonist for Gi1, Gi2 and Gi3. Mol. Pharmacol. 71 (2007) 1349-1359
-
(2007)
Mol. Pharmacol.
, vol.71
, pp. 1349-1359
-
-
Lane, J.R.1
-
47
-
-
0037350667
-
2 receptor with G alpha i1, G alpha i2, G alpha i3 and G alpha o G proteins: evidence for agonist regulation of G protein selectivity
-
2 receptor with G alpha i1, G alpha i2, G alpha i3 and G alpha o G proteins: evidence for agonist regulation of G protein selectivity. Br. J. Pharmacol. 138 (2003) 775-786
-
(2003)
Br. J. Pharmacol.
, vol.138
, pp. 775-786
-
-
Gazi, L.1
-
48
-
-
0028982509
-
2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate
-
2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate. Am. J. Psychiatry 152 (1995) 173-178
-
(1995)
Am. J. Psychiatry
, vol.152
, pp. 173-178
-
-
Nyberg, S.1
-
49
-
-
0034025771
-
Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia
-
Kapur S., et al. Relationship between dopamine D(2) occupancy, clinical response, and side effects: a double-blind PET study of first-episode schizophrenia. Am. J. Psychiatry 157 (2000) 514-520
-
(2000)
Am. J. Psychiatry
, vol.157
, pp. 514-520
-
-
Kapur, S.1
-
50
-
-
5444229688
-
2 receptors by the atypical antipsychotic drugs risperidone and olanzapine: theoretical implications
-
2 receptors by the atypical antipsychotic drugs risperidone and olanzapine: theoretical implications. Psychopharmacology (Berl.) 175 (2004) 473-480
-
(2004)
Psychopharmacology (Berl.)
, vol.175
, pp. 473-480
-
-
Frankle, W.G.1
-
51
-
-
0032987267
-
Increased dopamine transmission in schizophrenia: relationship to illness phases
-
Laruelle M., et al. Increased dopamine transmission in schizophrenia: relationship to illness phases. Biol. Psychiatry 46 (1999) 56-72
-
(1999)
Biol. Psychiatry
, vol.46
, pp. 56-72
-
-
Laruelle, M.1
-
52
-
-
0035983682
-
3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597): a study using positron emission tomography and [11C]raclopride
-
3 receptor occupancy in normal humans treated with the antipsychotic drug aripiprazole (OPC 14597): a study using positron emission tomography and [11C]raclopride. Neuropsychopharmacology 27 (2002) 248-259
-
(2002)
Neuropsychopharmacology
, vol.27
, pp. 248-259
-
-
Yokoi, F.1
-
53
-
-
34648830603
-
Differential effects of aripiprazole on D(2), 5-HT(2), and 5-HT(1A) receptor occupancy in patients with schizophrenia: a triple tracer PET study
-
Mamo D., et al. Differential effects of aripiprazole on D(2), 5-HT(2), and 5-HT(1A) receptor occupancy in patients with schizophrenia: a triple tracer PET study. Am. J. Psychiatry 164 (2007) 1411-1417
-
(2007)
Am. J. Psychiatry
, vol.164
, pp. 1411-1417
-
-
Mamo, D.1
-
54
-
-
0023878355
-
The structure and mechanism of neurotransmitter receptors. Implications for the structure and function of the central nervous system
-
Strange P.G. The structure and mechanism of neurotransmitter receptors. Implications for the structure and function of the central nervous system. Biochem. J. 249 (1988) 309-318
-
(1988)
Biochem. J.
, vol.249
, pp. 309-318
-
-
Strange, P.G.1
|