-
3
-
-
74049129976
-
Variants of DENND1B associated with asthma in children
-
Sleiman PM, Flory J, Imielinski M et al. Variants of DENND1B associated with asthma in children. N Engl J Med 2010: 362: 36-44.
-
(2010)
N Engl J Med
, vol.362
, pp. 36-44
-
-
Sleiman, P.M.1
Flory, J.2
Imielinski, M.3
-
4
-
-
40049088465
-
Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma
-
Hammad H, Lambrecht BN. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat Rev Immunol 2008: 8: 193-204.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 193-204
-
-
Hammad, H.1
Lambrecht, B.N.2
-
5
-
-
33645773245
-
Gene by environment interaction in asthma
-
Koppelman GH. Gene by environment interaction in asthma. Curr Allergy Asthma Rep 2006: 6: 103-11.
-
(2006)
Curr Allergy Asthma Rep
, vol.6
, pp. 103-111
-
-
Koppelman, G.H.1
-
7
-
-
41149090592
-
A genome-wide association scan for asthma in a general Australian population
-
Hui J, Oka A, James A et al. A genome-wide association scan for asthma in a general Australian population. Hum Genet 2008: 123: 297-306.
-
(2008)
Hum Genet
, vol.123
, pp. 297-306
-
-
Hui, J.1
Oka, A.2
James, A.3
-
8
-
-
81755165915
-
The pharmacogenetics and pharmacogenomics of asthma therapy
-
Tse SM, Tantisira K, Weiss ST. The pharmacogenetics and pharmacogenomics of asthma therapy. Pharmacogenomics J 2011: 11: 383-92.
-
(2011)
Pharmacogenomics J
, vol.11
, pp. 383-392
-
-
Tse, S.M.1
Tantisira, K.2
Weiss, S.T.3
-
9
-
-
75849162175
-
Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions
-
Li X, Howard TD, Zheng SL et al. Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions. J Allergy Clin Immunol 2010: 125: 328-35.
-
(2010)
J Allergy Clin Immunol
, vol.125
, pp. 328-335
-
-
Li, X.1
Howard, T.D.2
Zheng, S.L.3
-
10
-
-
80052298022
-
Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences
-
Kovacic MB, Myers JM, Wang N et al. Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences. PLoS One 2011: 6: e23714.
-
(2011)
PLoS One
, vol.6
-
-
Kovacic, M.B.1
Myers, J.M.2
Wang, N.3
-
11
-
-
40049100646
-
Discovering susceptibility genes for asthma and allergy
-
Vercelli D. Discovering susceptibility genes for asthma and allergy. Nat Rev Immunol 2008: 8: 169-82.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 169-182
-
-
Vercelli, D.1
-
12
-
-
34547216747
-
Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma
-
Moffatt MF, Kabesch M, Liang L et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature 2007: 448: 470-3.
-
(2007)
Nature
, vol.448
, pp. 470-473
-
-
Moffatt, M.F.1
Kabesch, M.2
Liang, L.3
-
13
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt MF, Gut IG, Demenais F et al. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 2010: 363: 1211-21.
-
(2010)
N Engl J Med
, vol.363
, pp. 1211-1221
-
-
Moffatt, M.F.1
Gut, I.G.2
Demenais, F.3
-
14
-
-
57349101088
-
Effect of 17q21 variants and smoking exposure in early-onset asthma
-
Bouzigon E, Corda E, Aschard H et al. Effect of 17q21 variants and smoking exposure in early-onset asthma. N Engl J Med 2008: 359: 1985-94.
-
(2008)
N Engl J Med
, vol.359
, pp. 1985-1994
-
-
Bouzigon, E.1
Corda, E.2
Aschard, H.3
-
15
-
-
84855928560
-
Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze
-
Bräuner EV, Loft S, Raaschou-Nielsen O, Vogel U, Andersen PS, Sørensen M. Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze. Genes Immun 2012: 13: 94-7.
-
(2012)
Genes Immun
, vol.13
, pp. 94-97
-
-
Bräuner, E.V.1
Loft, S.2
Raaschou-Nielsen, O.3
Vogel, U.4
Andersen, P.S.5
Sørensen, M.6
-
16
-
-
77954957118
-
A sequence variant on 17q21 is associated with age at onset and severity of asthma
-
Halapi E, Gudbjartsson DF, Jonsdottir GM et al. A sequence variant on 17q21 is associated with age at onset and severity of asthma. Eur J Hum Genet 2010: 18: 902-8.
-
(2010)
Eur J Hum Genet
, vol.18
, pp. 902-908
-
-
Halapi, E.1
Gudbjartsson, D.F.2
Jonsdottir, G.M.3
-
17
-
-
77954651403
-
17q21 variants modify the association between early respiratory infections and asthma
-
Smit LA, Bouzigon E, Pin I et al. 17q21 variants modify the association between early respiratory infections and asthma. Eur Respir J 2010: 36: 57-64.
-
(2010)
Eur Respir J
, vol.36
, pp. 57-64
-
-
Smit, L.A.1
Bouzigon, E.2
Pin, I.3
-
18
-
-
41549111983
-
A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications
-
Tavendale R, Macgregor DF, Mukhopadhyay S, Palmer CN. A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications. J Allergy Clin Immunol 2008: 121: 860-3.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 860-863
-
-
Tavendale, R.1
Macgregor, D.F.2
Mukhopadhyay, S.3
Palmer, C.N.4
-
19
-
-
44449150336
-
ORMDL3 gene is associated with asthma in three ethnically diverse populations
-
Galanter J, Choudhry S, Eng C et al. ORMDL3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med 2008: 177: 1194-200.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 1194-1200
-
-
Galanter, J.1
Choudhry, S.2
Eng, C.3
-
20
-
-
62449114842
-
Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma
-
Wu H, Romieu I, Sienra-Monge JJ, Li H, del Rio-Navarro BE, London SJ. Genetic variation in ORM1-like 3 (ORMDL3) and gasdermin-like (GSDML) and childhood asthma. Allergy 2009: 64: 629-35.
-
(2009)
Allergy
, vol.64
, pp. 629-635
-
-
Wu, H.1
Romieu, I.2
Sienra-Monge, J.J.3
Li, H.4
del Rio-Navarro, B.E.5
London, S.J.6
-
21
-
-
80255126299
-
Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population
-
Fang Q, Zhao H, Wang A, Gong Y, Liu Q. Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population. BMC Med Genet 2011: 12: 133.
-
(2011)
BMC Med Genet
, vol.12
, pp. 133
-
-
Fang, Q.1
Zhao, H.2
Wang, A.3
Gong, Y.4
Liu, Q.5
-
22
-
-
40049092784
-
Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population
-
Hirota T, Harada M, Sakashita M et al. Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population. J Allergy Clin Immunol 2008: 121: 769-70.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 769-770
-
-
Hirota, T.1
Harada, M.2
Sakashita, M.3
-
23
-
-
62449117832
-
Asthma and atopy are associated with chromosome 17q21 markers in Chinese children
-
Leung TF, Sy HY, Ng MC et al. Asthma and atopy are associated with chromosome 17q21 markers in Chinese children. Allergy 2009: 64: 621-8.
-
(2009)
Allergy
, vol.64
, pp. 621-628
-
-
Leung, T.F.1
Sy, H.Y.2
Ng, M.C.3
-
24
-
-
84884549617
-
Seasonal effects of UCP1 gene polymorphism on visceral fat accumulation in Japanese adults
-
Nakayama K, Miyashita H, Yanagisawa Y et al. Seasonal effects of UCP1 gene polymorphism on visceral fat accumulation in Japanese adults. PLoS One 2013: 8: e74720.
-
(2013)
PLoS One
, vol.8
-
-
Nakayama, K.1
Miyashita, H.2
Yanagisawa, Y.3
-
25
-
-
66149118652
-
MYLK polymorphism associated with blood eosinophil level among asthmatic patients in a Korean population
-
Lee SO, Cheong HS, Park BL et al. MYLK polymorphism associated with blood eosinophil level among asthmatic patients in a Korean population. Mol Cells 2009: 27: 175-81.
-
(2009)
Mol Cells
, vol.27
, pp. 175-181
-
-
Lee, S.O.1
Cheong, H.S.2
Park, B.L.3
-
26
-
-
79959815406
-
Polymorphisms in GSDMA and GSDMB are associated with asthma susceptibility, atopy and BHR
-
Yu J, Kang MJ, Kim BJ et al. Polymorphisms in GSDMA and GSDMB are associated with asthma susceptibility, atopy and BHR. Pediatr Pulmonol 2011: 46: 701-8.
-
(2011)
Pediatr Pulmonol
, vol.46
, pp. 701-708
-
-
Yu, J.1
Kang, M.J.2
Kim, B.J.3
-
27
-
-
84874948596
-
Single nucleotide polymorphisms in the ORM1-like 3 gene associated with childhood asthma in a Chinese population
-
Yang FF, Huang Y, Li QB, Dai JH, Fu Z. Single nucleotide polymorphisms in the ORM1-like 3 gene associated with childhood asthma in a Chinese population. Genet Mol Res 2012: 11: 4646-53.
-
(2012)
Genet Mol Res
, vol.11
, pp. 4646-4653
-
-
Yang, F.F.1
Huang, Y.2
Li, Q.B.3
Dai, J.H.4
Fu, Z.5
-
28
-
-
39049170984
-
Global strategy for asthma management and prevention: GINA executive summary
-
Bateman ED, Hurd SS, Barnes PJ et al. Global strategy for asthma management and prevention: GINA executive summary. Eur Respir J 2008: 31: 143-78.
-
(2008)
Eur Respir J
, vol.31
, pp. 143-178
-
-
Bateman, E.D.1
Hurd, S.S.2
Barnes, P.J.3
-
29
-
-
71449083275
-
Genomic dissection of population substructure of Han Chinese and its implication in association studies
-
Xu S, Yin X, Li S et al. Genomic dissection of population substructure of Han Chinese and its implication in association studies. Am J Hum Genet 2009: 85: 762-74.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 762-774
-
-
Xu, S.1
Yin, X.2
Li, S.3
-
30
-
-
79957835071
-
Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion
-
Lluis A, Schedel M, Liu J et al. Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion. J Allergy Clin Immunol 2011: 127: 1587-94.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 1587-1594
-
-
Lluis, A.1
Schedel, M.2
Liu, J.3
-
31
-
-
77649150074
-
The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress
-
Cantero-Recasens G, Fandos C, Rubio-Moscardo F, Valverde MA, Vicente R. The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress. Hum Mol Genet 2010: 19: 111-21.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 111-121
-
-
Cantero-Recasens, G.1
Fandos, C.2
Rubio-Moscardo, F.3
Valverde, M.A.4
Vicente, R.5
-
32
-
-
84867375353
-
ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6
-
Miller M, Tam AB, Cho JY et al. ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. Proc Natl Acad Sci U S A 2012: 109: 16648-53.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 16648-16653
-
-
Miller, M.1
Tam, A.B.2
Cho, J.Y.3
-
33
-
-
77649121162
-
Orm family proteins mediate sphingolipid homeostasis
-
Breslow DK, Collins SR, Bodenmiller B et al. Orm family proteins mediate sphingolipid homeostasis. Nature 2010: 463: 1048-53.
-
(2010)
Nature
, vol.463
, pp. 1048-1053
-
-
Breslow, D.K.1
Collins, S.R.2
Bodenmiller, B.3
-
34
-
-
77952787002
-
Alu-derived cis-element regulates tumorigenesis-dependent gastric expression of GASDERMIN B (GSDMB)
-
Komiyama H, Aoki A, Tanaka S et al. Alu-derived cis-element regulates tumorigenesis-dependent gastric expression of GASDERMIN B (GSDMB). Genes Genet Syst 2010: 85: 75-83.
-
(2010)
Genes Genet Syst
, vol.85
, pp. 75-83
-
-
Komiyama, H.1
Aoki, A.2
Tanaka, S.3
-
35
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008: 40: 955-62.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
-
36
-
-
67349199566
-
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
-
Barrett JC, Clayton DG, Concannon P et al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet 2009: 41: 703-7.
-
(2009)
Nat Genet
, vol.41
, pp. 703-707
-
-
Barrett, J.C.1
Clayton, D.G.2
Concannon, P.3
-
37
-
-
67149095289
-
Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants
-
Hirschfield GM et al. Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N Engl J Med 2009: 360: 2544-55.
-
(2009)
N Engl J Med
, vol.360
, pp. 2544-2555
-
-
Hirschfield, G.M.1
-
38
-
-
69449101386
-
Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease
-
Verlaan DJ, Berlivet S, Hunninghake GM et al. Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease. Am J Hum Genet 2009: 85: 377-93.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 377-393
-
-
Verlaan, D.J.1
Berlivet, S.2
Hunninghake, G.M.3
|