메뉴 건너뛰기




Volumn 6, Issue 8, 2011, Pages

Identification of KIF3A as a novel candidate gene for childhood asthma using RNA expression and population allelic frequencies differences

(28)  Kovacic, Melinda Butsch a   Myers, Jocelyn M Biagini a   Wang, Ning a   Martin, Lisa J a   Lindsey, Mark a   Ericksen, Mark B a   He, Hua a   Patterson, Tia L a   Baye, Tesfaye M a   Torgerson, Dara c   Roth, Lindsey A c   Gupta, Jayanta a   Sivaprasad, Umasundari a   Gibson, Aaron M a   Tsoras, Anna M a   Hu, Donglei b,c   Eng, Celeste b,c   Chapela, Rocío d   Rodríguez Santana, José R e   Rodríguez Cintrón, William f   more..


Author keywords

[No Author keywords available]

Indexed keywords

RNA; KIF3A PROTEIN, HUMAN; KINESIN;

EID: 80052298022     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0023714     Document Type: Article
Times cited : (47)

References (48)
  • 3
    • 33644774556 scopus 로고    scopus 로고
    • Asthma genetics 2006: the long and winding road to gene discovery
    • Ober C, Hoffjan S, (2006) Asthma genetics 2006: the long and winding road to gene discovery. Genes Immun 7: 95-100.
    • (2006) Genes Immun , vol.7 , pp. 95-100
    • Ober, C.1    Hoffjan, S.2
  • 4
    • 0036911353 scopus 로고    scopus 로고
    • Interrogating a high-density SNP map for signatures of natural selection
    • Akey JM, Zhang G, Zhang K, Jin L, Shriver MD, (2002) Interrogating a high-density SNP map for signatures of natural selection. Genome Res 12: 1805-1814.
    • (2002) Genome Res , vol.12 , pp. 1805-1814
    • Akey, J.M.1    Zhang, G.2    Zhang, K.3    Jin, L.4    Shriver, M.D.5
  • 6
    • 13444280369 scopus 로고    scopus 로고
    • Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma
    • Guajardo JR, Schleifer KW, Daines MO, Ruddy RM, Aronow BJ, et al. (2005) Altered gene expression profiles in nasal respiratory epithelium reflect stable versus acute childhood asthma. J Allergy Clin Immunol 115: 243-251.
    • (2005) J Allergy Clin Immunol , vol.115 , pp. 243-251
    • Guajardo, J.R.1    Schleifer, K.W.2    Daines, M.O.3    Ruddy, R.M.4    Aronow, B.J.5
  • 7
    • 23244461860 scopus 로고    scopus 로고
    • Asthma concepts in the new millennium: update in asthma pathophysiology
    • Frieri M, (2005) Asthma concepts in the new millennium: update in asthma pathophysiology. Allergy Asthma Proc 26: 83-88.
    • (2005) Allergy Asthma Proc , vol.26 , pp. 83-88
    • Frieri, M.1
  • 8
    • 10244250341 scopus 로고    scopus 로고
    • The immunogenetics of asthma and eczema: a new focus on the epithelium
    • Cookson W, (2004) The immunogenetics of asthma and eczema: a new focus on the epithelium. Nat Rev Immunol 4: 978-988.
    • (2004) Nat Rev Immunol , vol.4 , pp. 978-988
    • Cookson, W.1
  • 9
    • 0034072016 scopus 로고    scopus 로고
    • Eosinophils are a feature of upper and lower airway pathology in non-atopic asthma, irrespective of the presence of rhinitis
    • Gaga M, Lambrou P, Papageorgiou N, Koulouris NG, Kosmas E, et al. (2000) Eosinophils are a feature of upper and lower airway pathology in non-atopic asthma, irrespective of the presence of rhinitis. Clin Exp Allergy 30: 663-669.
    • (2000) Clin Exp Allergy , vol.30 , pp. 663-669
    • Gaga, M.1    Lambrou, P.2    Papageorgiou, N.3    Koulouris, N.G.4    Kosmas, E.5
  • 11
  • 12
    • 9144227391 scopus 로고    scopus 로고
    • Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma
    • Burchard EG, Avila PC, Nazario S, Casal J, Torres A, et al. (2004) Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma. Am J Respir Crit Care Med 169: 386-392.
    • (2004) Am J Respir Crit Care Med , vol.169 , pp. 386-392
    • Burchard, E.G.1    Avila, P.C.2    Nazario, S.3    Casal, J.4    Torres, A.5
  • 13
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, et al. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38: 904-909.
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5
  • 14
    • 0042613503 scopus 로고
    • Principal Component Analysis for Large Dispersion Matrices
    • Narayanaswamy CRaR, D., (1991) Principal Component Analysis for Large Dispersion Matrices. App Stat 40: 309-316.
    • (1991) App Stat , vol.40 , pp. 309-316
    • Narayanaswamy, C.R.R.D.1
  • 15
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: a tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-575.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.5
  • 16
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie BN, Donnelly P, Marchini J, (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet 5: e1000529.
    • (2009) PLoS Genet , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 19
    • 60049090583 scopus 로고    scopus 로고
    • Point and interval estimation of partial attributable risks from case-control data using the R-package 'pARccs'
    • Ramsch C, Pfahlberg AB, Gefeller O, (2009) Point and interval estimation of partial attributable risks from case-control data using the R-package 'pARccs'. Comput Methods Programs Biomed 94: 88-95.
    • (2009) Comput Methods Programs Biomed , vol.94 , pp. 88-95
    • Ramsch, C.1    Pfahlberg, A.B.2    Gefeller, O.3
  • 20
    • 0032231748 scopus 로고    scopus 로고
    • Mapping genes that underlie ethnic differences in disease risk: methods for detecting linkage in admixed populations, by conditioning on parental admixture
    • McKeigue PM, (1998) Mapping genes that underlie ethnic differences in disease risk: methods for detecting linkage in admixed populations, by conditioning on parental admixture. Am J Hum Genet 63: 241-251.
    • (1998) Am J Hum Genet , vol.63 , pp. 241-251
    • McKeigue, P.M.1
  • 21
    • 80052295098 scopus 로고
    • Variability within and among Natural Populations: University of Chicago Press
    • Wright S, (1978) Variability within and among Natural Populations: University of Chicago Press.
    • (1978)
    • Wright, S.1
  • 22
    • 84890417804 scopus 로고
    • The genetic structure of populations
    • Wright S, (1951) The genetic structure of populations. Ann Eugen 15: 323-354.
    • (1951) Ann Eugen , vol.15 , pp. 323-354
    • Wright, S.1
  • 23
    • 70949094320 scopus 로고    scopus 로고
    • Genome-wide scan for signatures of human population differentiation and their relationship with natural selection, functional pathways and diseases
    • Amato R, Pinelli M, Monticelli A, Marino D, Miele G, et al. (2009) Genome-wide scan for signatures of human population differentiation and their relationship with natural selection, functional pathways and diseases. PLoS One 4: e7927.
    • (2009) PLoS One , vol.4
    • Amato, R.1    Pinelli, M.2    Monticelli, A.3    Marino, D.4    Miele, G.5
  • 24
    • 0032565364 scopus 로고    scopus 로고
    • Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC
    • The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee
    • The International Study of Asthma and Allergies in Childhood (ISAAC) Steering Committee (1998) Worldwide variation in prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and atopic eczema: ISAAC. Lancet 351: 1225-1232.
    • (1998) Lancet , vol.351 , pp. 1225-1232
  • 25
    • 0000762002 scopus 로고
    • Definition and estimation of fixation indices
    • Nei M, (1986) Definition and estimation of fixation indices. Evolution 40: 643-645.
    • (1986) Evolution , vol.40 , pp. 643-645
    • Nei, M.1
  • 26
    • 0021566877 scopus 로고
    • Estimating F-statistics for the analysis of population structure
    • Weir B, (1984) Estimating F-statistics for the analysis of population structure. Evolution 38: 1358-1370.
    • (1984) Evolution , vol.38 , pp. 1358-1370
    • Weir, B.1
  • 27
    • 0346373654 scopus 로고    scopus 로고
    • Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium
    • Carlson CS, Eberle MA, Rieder MJ, Yi Q, Kruglyak L, et al. (2004) Selecting a maximally informative set of single-nucleotide polymorphisms for association analyses using linkage disequilibrium. Am J Hum Genet 74: 106-120.
    • (2004) Am J Hum Genet , vol.74 , pp. 106-120
    • Carlson, C.S.1    Eberle, M.A.2    Rieder, M.J.3    Yi, Q.4    Kruglyak, L.5
  • 28
    • 0037311771 scopus 로고    scopus 로고
    • Efficient selective screening of haplotype tag SNPs
    • Ke X, Cardon LR, (2003) Efficient selective screening of haplotype tag SNPs. Bioinformatics 19: 287-288.
    • (2003) Bioinformatics , vol.19 , pp. 287-288
    • Ke, X.1    Cardon, L.R.2
  • 30
    • 0347362518 scopus 로고    scopus 로고
    • Informativeness of genetic markers for inference of ancestry
    • Rosenberg NA, Li LM, Ward R, Pritchard JK, (2003) Informativeness of genetic markers for inference of ancestry. Am J Hum Genet 73: 1402-1422.
    • (2003) Am J Hum Genet , vol.73 , pp. 1402-1422
    • Rosenberg, N.A.1    Li, L.M.2    Ward, R.3    Pritchard, J.K.4
  • 31
    • 57549090341 scopus 로고    scopus 로고
    • Accounting for ancestry: population substructure and genome-wide association studies
    • Tian C, Gregersen PK, Seldin MF, (2008) Accounting for ancestry: population substructure and genome-wide association studies. Hum Mol Genet 17: R143-150.
    • (2008) Hum Mol Genet , vol.17 , pp. 143-150
    • Tian, C.1    Gregersen, P.K.2    Seldin, M.F.3
  • 32
    • 0023567409 scopus 로고
    • Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986
    • (1987) Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986. Am Rev Respir Dis 136: 225-244.
    • (1987) Am Rev Respir Dis , vol.136 , pp. 225-244
  • 33
    • 25144467060 scopus 로고    scopus 로고
    • Racial and ethnic differences in asthma diagnosis among children who wheeze
    • Akinbami LJ, Rhodes JC, Lara M, (2005) Racial and ethnic differences in asthma diagnosis among children who wheeze. Pediatrics 115: 1254-1260.
    • (2005) Pediatrics , vol.115 , pp. 1254-1260
    • Akinbami, L.J.1    Rhodes, J.C.2    Lara, M.3
  • 34
    • 0038056250 scopus 로고    scopus 로고
    • Prevalence and risk factors of asthma and wheezing among US adults: an analysis of the NHANES III data
    • Arif AA, Delclos GL, Lee ES, Tortolero SR, Whitehead LW, (2003) Prevalence and risk factors of asthma and wheezing among US adults: an analysis of the NHANES III data. Eur Respir J 21: 827-833.
    • (2003) Eur Respir J , vol.21 , pp. 827-833
    • Arif, A.A.1    Delclos, G.L.2    Lee, E.S.3    Tortolero, S.R.4    Whitehead, L.W.5
  • 36
    • 0027417365 scopus 로고
    • Reported asthma among Puerto Rican, Mexican-American, and Cuban children, 1982 through 1984
    • Carter-Pokras OD, Gergen PJ, (1993) Reported asthma among Puerto Rican, Mexican-American, and Cuban children, 1982 through 1984. Am J Public Health 83: 580-582.
    • (1993) Am J Public Health , vol.83 , pp. 580-582
    • Carter-Pokras, O.D.1    Gergen, P.J.2
  • 37
    • 0037014644 scopus 로고    scopus 로고
    • The health of Latino children: urgent priorities, unanswered questions, and a research agenda
    • Flores G, Fuentes-Afflick E, Barbot O, Carter-Pokras O, Claudio L, et al. (2002) The health of Latino children: urgent priorities, unanswered questions, and a research agenda. JAMA 288: 82-90.
    • (2002) JAMA , vol.288 , pp. 82-90
    • Flores, G.1    Fuentes-Afflick, E.2    Barbot, O.3    Carter-Pokras, O.4    Claudio, L.5
  • 38
    • 33644840164 scopus 로고    scopus 로고
    • Heterogeneity of childhood asthma among Hispanic children: Puerto Rican children bear a disproportionate burden
    • Lara M, Akinbami L, Flores G, Morgenstern H, (2006) Heterogeneity of childhood asthma among Hispanic children: Puerto Rican children bear a disproportionate burden. Pediatrics 117: 43-53.
    • (2006) Pediatrics , vol.117 , pp. 43-53
    • Lara, M.1    Akinbami, L.2    Flores, G.3    Morgenstern, H.4
  • 39
  • 40
    • 0029155982 scopus 로고
    • KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport
    • Yamazaki H, Nakata T, Okada Y, Hirokawa N, (1995) KIF3A/B: a heterodimeric kinesin superfamily protein that works as a microtubule plus end-directed motor for membrane organelle transport. J Cell Biol 130: 1387-1399.
    • (1995) J Cell Biol , vol.130 , pp. 1387-1399
    • Yamazaki, H.1    Nakata, T.2    Okada, Y.3    Hirokawa, N.4
  • 41
    • 4444317306 scopus 로고    scopus 로고
    • The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds
    • Zhang Y, Hancock WO, (2004) The two motor domains of KIF3A/B coordinate for processive motility and move at different speeds. Biophys J 87: 1795-1804.
    • (2004) Biophys J , vol.87 , pp. 1795-1804
    • Zhang, Y.1    Hancock, W.O.2
  • 42
    • 35448961665 scopus 로고    scopus 로고
    • When cilia go bad: cilia defects and ciliopathies
    • Fliegauf M, Benzing T, Omran H, (2007) When cilia go bad: cilia defects and ciliopathies. Nat Rev Mol Cell Biol 8: 880-893.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 880-893
    • Fliegauf, M.1    Benzing, T.2    Omran, H.3
  • 43
    • 45949094270 scopus 로고    scopus 로고
    • Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models
    • Mall MA, (2008) Role of cilia, mucus, and airway surface liquid in mucociliary dysfunction: lessons from mouse models. J Aerosol Med Pulm Drug Deliv 21: 13-24.
    • (2008) J Aerosol Med Pulm Drug Deliv , vol.21 , pp. 13-24
    • Mall, M.A.1
  • 44
    • 33947545950 scopus 로고    scopus 로고
    • Interleukin-4 promoter polymorphisms: a genetic prognostic factor for survival in metastatic renal cell carcinoma
    • Kleinrath T, Gassner C, Lackner P, Thurnher M, Ramoner R, (2007) Interleukin-4 promoter polymorphisms: a genetic prognostic factor for survival in metastatic renal cell carcinoma. J Clin Oncol 25: 845-851.
    • (2007) J Clin Oncol , vol.25 , pp. 845-851
    • Kleinrath, T.1    Gassner, C.2    Lackner, P.3    Thurnher, M.4    Ramoner, R.5
  • 45
    • 35348983887 scopus 로고    scopus 로고
    • A second generation human haplotype map of over 3.1 million SNPs
    • Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, et al. (2007) A second generation human haplotype map of over 3.1 million SNPs. Nature 449: 851-861.
    • (2007) Nature , vol.449 , pp. 851-861
    • Frazer, K.A.1    Ballinger, D.G.2    Cox, D.R.3    Hinds, D.A.4    Stuve, L.L.5
  • 46
    • 0242467244 scopus 로고    scopus 로고
    • A complete screening of the IL4 gene: novel polymorphisms and their association with asthma and IgE in childhood
    • Kabesch M, Tzotcheva I, Carr D, Hofler C, Weiland SK, et al. (2003) A complete screening of the IL4 gene: novel polymorphisms and their association with asthma and IgE in childhood. J Allergy Clin Immunol 112: 893-898.
    • (2003) J Allergy Clin Immunol , vol.112 , pp. 893-898
    • Kabesch, M.1    Tzotcheva, I.2    Carr, D.3    Hofler, C.4    Weiland, S.K.5
  • 47
    • 79953839156 scopus 로고    scopus 로고
    • Expression of Cilia Structural Genes is Downregulated in Asthma and Single Nucleotide Polymorphisms in These Genes Correlate with Asthma
    • Sivaprasad U, Gibson AM, Wang N, Hershey GKK, (2009) Expression of Cilia Structural Genes is Downregulated in Asthma and Single Nucleotide Polymorphisms in These Genes Correlate with Asthma. The Journal of Allergy and Clinical Immunology 123: S81.
    • (2009) The Journal of Allergy and Clinical Immunology , vol.123
    • Sivaprasad, U.1    Gibson, A.M.2    Wang, N.3    Hershey, G.K.K.4
  • 48
    • 79953887781 scopus 로고    scopus 로고
    • KIF3A, a cilia structural gene on chromosome 5q31, and its polymorphisms show an association with aspirin hypersensitivity in asthma
    • Kim JH, Cha JY, Cheong HS, Park JS, Jang AS, et al. (2011) KIF3A, a cilia structural gene on chromosome 5q31, and its polymorphisms show an association with aspirin hypersensitivity in asthma. Journal of Clinical Immunology 31: 112-121.
    • (2011) Journal of Clinical Immunology , vol.31 , pp. 112-121
    • Kim, J.H.1    Cha, J.Y.2    Cheong, H.S.3    Park, J.S.4    Jang, A.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.