-
1
-
-
34249689753
-
Molecular regulation of angiogenesis and lymphangiogenesis
-
Adams R.H., Alitalo K. Molecular regulation of angiogenesis and lymphangiogenesis. Nat. Rev. Mol. Cell Biol. 2007, 8:464-478.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 464-478
-
-
Adams, R.H.1
Alitalo, K.2
-
2
-
-
3142724031
-
Toll-like receptor signalling
-
Akira S., Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 2004, 4:499-511.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 499-511
-
-
Akira, S.1
Takeda, K.2
-
3
-
-
84867713025
-
The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock
-
Aksoy E., Taboubi S., Torres D., Delbauve S., Hachani A., Whitehead M.A., Pearce W.P., Berenjeno I.M., Nock G., Filloux A., et al. The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock. Nat. Immunol. 2012, 13:1045-1054.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 1045-1054
-
-
Aksoy, E.1
Taboubi, S.2
Torres, D.3
Delbauve, S.4
Hachani, A.5
Whitehead, M.A.6
Pearce, W.P.7
Berenjeno, I.M.8
Nock, G.9
Filloux, A.10
-
4
-
-
30744477450
-
Lymphangiogenesis in development and human disease
-
Alitalo K., Tammela T., Petrova T.V. Lymphangiogenesis in development and human disease. Nature 2005, 438:946-953.
-
(2005)
Nature
, vol.438
, pp. 946-953
-
-
Alitalo, K.1
Tammela, T.2
Petrova, T.V.3
-
5
-
-
68649091506
-
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs
-
Androulidaki A., Iliopoulos D., Arranz A., Doxaki C., Schworer S., Zacharioudaki V., Margioris A.N., Tsichlis P.N., Tsatsanis C. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity 2009, 31:220-231.
-
(2009)
Immunity
, vol.31
, pp. 220-231
-
-
Androulidaki, A.1
Iliopoulos, D.2
Arranz, A.3
Doxaki, C.4
Schworer, S.5
Zacharioudaki, V.6
Margioris, A.N.7
Tsichlis, P.N.8
Tsatsanis, C.9
-
6
-
-
70349559403
-
Endotoxin tolerance: new mechanisms, molecules and clinical significance
-
Biswas S.K., Lopez-Collazo E. Endotoxin tolerance: new mechanisms, molecules and clinical significance. Trends Immunol. 2009, 30:475-487.
-
(2009)
Trends Immunol.
, vol.30
, pp. 475-487
-
-
Biswas, S.K.1
Lopez-Collazo, E.2
-
7
-
-
80051488597
-
Dynamics of the phosphoinositide 3-kinase p110δ interaction with p85α and membranes reveals aspects of regulation distinct from p110α
-
Burke J.E., Vadas O., Berndt A., Finegan T., Perisic O., Williams R.L. Dynamics of the phosphoinositide 3-kinase p110δ interaction with p85α and membranes reveals aspects of regulation distinct from p110α. Structure 2011, 19:1127-1137.
-
(2011)
Structure
, vol.19
, pp. 1127-1137
-
-
Burke, J.E.1
Vadas, O.2
Berndt, A.3
Finegan, T.4
Perisic, O.5
Williams, R.L.6
-
8
-
-
17044458971
-
Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites
-
Dixelius J., Makinen T., Wirzenius M., Karkkainen M.J., Wernstedt C., Alitalo K., Claesson-Welsh L. Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites. J.Biol. Chem. 2003, 278:40973-40979.
-
(2003)
J.Biol. Chem.
, vol.278
, pp. 40973-40979
-
-
Dixelius, J.1
Makinen, T.2
Wirzenius, M.3
Karkkainen, M.J.4
Wernstedt, C.5
Alitalo, K.6
Claesson-Welsh, L.7
-
9
-
-
36849082588
-
Non-conventional signal transduction by type 1 interferons: the NF-kappaB pathway
-
Du Z., Wei L., Murti A., Pfeffer S.R., Fan M., Yang C.H., Pfeffer L.M. Non-conventional signal transduction by type 1 interferons: the NF-kappaB pathway. J.Cell. Biochem. 2007, 102:1087-1094.
-
(2007)
J.Cell. Biochem.
, vol.102
, pp. 1087-1094
-
-
Du, Z.1
Wei, L.2
Murti, A.3
Pfeffer, S.R.4
Fan, M.5
Yang, C.H.6
Pfeffer, L.M.7
-
10
-
-
0032582502
-
Cardiovascular failure in mouse embryos deficient in VEGF receptor-3
-
Dumont D.J., Jussila L., Taipale J., Lymboussaki A., Mustonen T., Pajusola K., Breitman M., Alitalo K. Cardiovascular failure in mouse embryos deficient in VEGF receptor-3. Science 1998, 282:946-949.
-
(1998)
Science
, vol.282
, pp. 946-949
-
-
Dumont, D.J.1
Jussila, L.2
Taipale, J.3
Lymboussaki, A.4
Mustonen, T.5
Pajusola, K.6
Breitman, M.7
Alitalo, K.8
-
11
-
-
31044453678
-
SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling
-
Evel-Kabler K., Song X.T., Aldrich M., Huang X.F., Chen S.Y. SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling. J.Clin. Invest. 2006, 116:90-100.
-
(2006)
J.Clin. Invest.
, vol.116
, pp. 90-100
-
-
Evel-Kabler, K.1
Song, X.T.2
Aldrich, M.3
Huang, X.F.4
Chen, S.Y.5
-
12
-
-
0037199972
-
The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells
-
Guha M., Mackman N. The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells. J.Biol. Chem. 2002, 277:32124-32132.
-
(2002)
J.Biol. Chem.
, vol.277
, pp. 32124-32132
-
-
Guha, M.1
Mackman, N.2
-
13
-
-
77951813014
-
Sepsis: calming the cytokine storm
-
Harrison C. Sepsis: calming the cytokine storm. Nat. Rev. Drug Discov. 2010, 9:360-361.
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 360-361
-
-
Harrison, C.1
-
14
-
-
41149113441
-
The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells
-
Haxhinasto S., Mathis D., Benoist C. The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells. J.Exp. Med. 2008, 205:565-574.
-
(2008)
J.Exp. Med.
, vol.205
, pp. 565-574
-
-
Haxhinasto, S.1
Mathis, D.2
Benoist, C.3
-
15
-
-
0031860393
-
Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL
-
Heinemeyer T., Wingender E., Reuter I., Hermjakob H., Kel A.E., Kel O.V., Ignatieva E.V., Ananko E.A., Podkolodnaya O.A., Kolpakov F.A., et al. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Res. 1998, 26:362-367.
-
(1998)
Nucleic Acids Res.
, vol.26
, pp. 362-367
-
-
Heinemeyer, T.1
Wingender, E.2
Reuter, I.3
Hermjakob, H.4
Kel, A.E.5
Kel, O.V.6
Ignatieva, E.V.7
Ananko, E.A.8
Podkolodnaya, O.A.9
Kolpakov, F.A.10
-
16
-
-
79955957828
-
An important role of lymphatic vessel activation in limiting acute inflammation
-
Huggenberger R., Siddiqui S.S., Brander D., Ullmann S., Zimmermann K., Antsiferova M., Werner S., Alitalo K., Detmar M. An important role of lymphatic vessel activation in limiting acute inflammation. Blood 2011, 117:4667-4678.
-
(2011)
Blood
, vol.117
, pp. 4667-4678
-
-
Huggenberger, R.1
Siddiqui, S.S.2
Brander, D.3
Ullmann, S.4
Zimmermann, K.5
Antsiferova, M.6
Werner, S.7
Alitalo, K.8
Detmar, M.9
-
17
-
-
0034693879
-
Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis
-
Karkkainen M.J., Petrova T.V. Vascular endothelial growth factor receptors in the regulation of angiogenesis and lymphangiogenesis. Oncogene 2000, 19:5598-5605.
-
(2000)
Oncogene
, vol.19
, pp. 5598-5605
-
-
Karkkainen, M.J.1
Petrova, T.V.2
-
18
-
-
0034041161
-
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
-
Karkkainen M.J., Ferrell R.E., Lawrence E.C., Kimak M.A., Levinson K.L., McTigue M.A., Alitalo K., Finegold D.N. Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema. Nat. Genet. 2000, 25:153-159.
-
(2000)
Nat. Genet.
, vol.25
, pp. 153-159
-
-
Karkkainen, M.J.1
Ferrell, R.E.2
Lawrence, E.C.3
Kimak, M.A.4
Levinson, K.L.5
McTigue, M.A.6
Alitalo, K.7
Finegold, D.N.8
-
19
-
-
0035940403
-
A model for gene therapy of human hereditary lymphedema
-
Karkkainen M.J., Saaristo A., Jussila L., Karila K.A., Lawrence E.C., Pajusola K., Bueler H., Eichmann A., Kauppinen R., Kettunen M.I., et al. A model for gene therapy of human hereditary lymphedema. Proc. Natl. Acad. Sci. USA 2001, 98:12677-12682.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12677-12682
-
-
Karkkainen, M.J.1
Saaristo, A.2
Jussila, L.3
Karila, K.A.4
Lawrence, E.C.5
Pajusola, K.6
Bueler, H.7
Eichmann, A.8
Kauppinen, R.9
Kettunen, M.I.10
-
20
-
-
9144236286
-
Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins
-
Karkkainen M.J., Haiko P., Sainio K., Partanen J., Taipale J., Petrova T.V., Jeltsch M., Jackson D.G., Talikka M., Rauvala H., et al. Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat. Immunol. 2004, 5:74-80.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 74-80
-
-
Karkkainen, M.J.1
Haiko, P.2
Sainio, K.3
Partanen, J.4
Taipale, J.5
Petrova, T.V.6
Jeltsch, M.7
Jackson, D.G.8
Talikka, M.9
Rauvala, H.10
-
21
-
-
67049167170
-
Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution
-
Kataru R.P., Jung K., Jang C., Yang H., Schwendener R.A., Baik J.E., Han S.H., Alitalo K., Koh G.Y. Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution. Blood 2009, 113:5650-5659.
-
(2009)
Blood
, vol.113
, pp. 5650-5659
-
-
Kataru, R.P.1
Jung, K.2
Jang, C.3
Yang, H.4
Schwendener, R.A.5
Baik, J.E.6
Han, S.H.7
Alitalo, K.8
Koh, G.Y.9
-
22
-
-
77954709866
-
Activation of murine macrophages via TLR2 and TLR4 is negatively regulated by a Lyn/PI3K module and promoted by SHIP1
-
Keck S., Freudenberg M., Huber M. Activation of murine macrophages via TLR2 and TLR4 is negatively regulated by a Lyn/PI3K module and promoted by SHIP1. J.Immunol. 2010, 184:5809-5818.
-
(2010)
J.Immunol.
, vol.184
, pp. 5809-5818
-
-
Keck, S.1
Freudenberg, M.2
Huber, M.3
-
23
-
-
0036850946
-
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation
-
Kinjyo I., Hanada T., Inagaki-Ohara K., Mori H., Aki D., Ohishi M., Yoshida H., Kubo M., Yoshimura A. SOCS1/JAB is a negative regulator of LPS-induced macrophage activation. Immunity 2002, 17:583-591.
-
(2002)
Immunity
, vol.17
, pp. 583-591
-
-
Kinjyo, I.1
Hanada, T.2
Inagaki-Ohara, K.3
Mori, H.4
Aki, D.5
Ohishi, M.6
Yoshida, H.7
Kubo, M.8
Yoshimura, A.9
-
24
-
-
8644256083
-
MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth invitro, suppresses tumor growth invivo
-
Kirkin V., Thiele W., Baumann P., Mazitschek R., Rohde K., Fellbrich G., Weich H., Waltenberger J., Giannis A., Sleeman J.P. MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth invitro, suppresses tumor growth invivo. Int. J. Cancer 2004, 112:986-993.
-
(2004)
Int. J. Cancer
, vol.112
, pp. 986-993
-
-
Kirkin, V.1
Thiele, W.2
Baumann, P.3
Mazitschek, R.4
Rohde, K.5
Fellbrich, G.6
Weich, H.7
Waltenberger, J.8
Giannis, A.9
Sleeman, J.P.10
-
25
-
-
84865298775
-
Dissecting negative regulation of Toll-like receptor signaling
-
Kondo T., Kawai T., Akira S. Dissecting negative regulation of Toll-like receptor signaling. Trends Immunol. 2012, 33:449-458.
-
(2012)
Trends Immunol.
, vol.33
, pp. 449-458
-
-
Kondo, T.1
Kawai, T.2
Akira, S.3
-
26
-
-
0030453355
-
VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development
-
Kukk E., Lymboussaki A., Taira S., Kaipainen A., Jeltsch M., Joukov V., Alitalo K. VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development 1996, 122:3829-3837.
-
(1996)
Development
, vol.122
, pp. 3829-3837
-
-
Kukk, E.1
Lymboussaki, A.2
Taira, S.3
Kaipainen, A.4
Jeltsch, M.5
Joukov, V.6
Alitalo, K.7
-
27
-
-
33846688115
-
Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth
-
Laakkonen P., Waltari M., Holopainen T., Takahashi T., Pytowski B., Steiner P., Hicklin D., Persaud K., Tonra J.R., Witte L., Alitalo K. Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth. Cancer Res. 2007, 67:593-599.
-
(2007)
Cancer Res.
, vol.67
, pp. 593-599
-
-
Laakkonen, P.1
Waltari, M.2
Holopainen, T.3
Takahashi, T.4
Pytowski, B.5
Steiner, P.6
Hicklin, D.7
Persaud, K.8
Tonra, J.R.9
Witte, L.10
Alitalo, K.11
-
28
-
-
20644450804
-
Negative regulation oftoll-like receptor-mediated immune responses
-
Liew F.Y., Xu D., Brint E.K., O'Neill L.A. Negative regulation oftoll-like receptor-mediated immune responses. Nat. Rev. Immunol. 2005, 5:446-458.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 446-458
-
-
Liew, F.Y.1
Xu, D.2
Brint, E.K.3
O'Neill, L.A.4
-
29
-
-
63749125392
-
VEGFs and receptors involved in angiogenesis versus lymphangiogenesis
-
Lohela M., Bry M., Tammela T., Alitalo K. VEGFs and receptors involved in angiogenesis versus lymphangiogenesis. Curr. Opin. Cell Biol. 2009, 21:154-165.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 154-165
-
-
Lohela, M.1
Bry, M.2
Tammela, T.3
Alitalo, K.4
-
30
-
-
35648992652
-
Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems
-
Lundberg A.M., Drexler S.K., Monaco C., Williams L.M., Sacre S.M., Feldmann M., Foxwell B.M. Key differences in TLR3/poly I:C signaling and cytokine induction by human primary cells: a phenomenon absent from murine cell systems. Blood 2007, 110:3245-3252.
-
(2007)
Blood
, vol.110
, pp. 3245-3252
-
-
Lundberg, A.M.1
Drexler, S.K.2
Monaco, C.3
Williams, L.M.4
Sacre, S.M.5
Feldmann, M.6
Foxwell, B.M.7
-
31
-
-
31344467156
-
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
-
Mansell A., Smith R., Doyle S.L., Gray P., Fenner J.E., Crack P.J., Nicholson S.E., Hilton D.J., O'Neill L.A., Hertzog P.J. Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation. Nat. Immunol. 2006, 7:148-155.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 148-155
-
-
Mansell, A.1
Smith, R.2
Doyle, S.L.3
Gray, P.4
Fenner, J.E.5
Crack, P.J.6
Nicholson, S.E.7
Hilton, D.J.8
O'Neill, L.A.9
Hertzog, P.J.10
-
32
-
-
23944486750
-
Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
-
Martin M., Rehani K., Jope R.S., Michalek S.M. Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. Nat. Immunol. 2005, 6:777-784.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 777-784
-
-
Martin, M.1
Rehani, K.2
Jope, R.S.3
Michalek, S.M.4
-
33
-
-
18744371050
-
SOCS-1 participates in negative regulation of LPS responses
-
Nakagawa R., Naka T., Tsutsui H., Fujimoto M., Kimura A., Abe T., Seki E., Sato S., Takeuchi O., Takeda K., et al. SOCS-1 participates in negative regulation of LPS responses. Immunity 2002, 17:677-687.
-
(2002)
Immunity
, vol.17
, pp. 677-687
-
-
Nakagawa, R.1
Naka, T.2
Tsutsui, H.3
Fujimoto, M.4
Kimura, A.5
Abe, T.6
Seki, E.7
Sato, S.8
Takeuchi, O.9
Takeda, K.10
-
34
-
-
20244384395
-
Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression
-
Nomura F., Akashi S., Sakao Y., Sato S., Kawai T., Matsumoto M., Nakanishi K., Kimoto M., Miyake K., Takeda K., Akira S. Cutting edge: endotoxin tolerance in mouse peritoneal macrophages correlates with down-regulation of surface toll-like receptor 4 expression. J.Immunol. 2000, 164:3476-3479.
-
(2000)
J.Immunol.
, vol.164
, pp. 3476-3479
-
-
Nomura, F.1
Akashi, S.2
Sakao, Y.3
Sato, S.4
Kawai, T.5
Matsumoto, M.6
Nakanishi, K.7
Kimoto, M.8
Miyake, K.9
Takeda, K.10
Akira, S.11
-
35
-
-
33646107369
-
VEGF receptor signalling - in control of vascular function
-
Olsson A.K., Dimberg A., Kreuger J., Claesson-Welsh L. VEGF receptor signalling - in control of vascular function. Nat. Rev. Mol. Cell Biol. 2006, 7:359-371.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 359-371
-
-
Olsson, A.K.1
Dimberg, A.2
Kreuger, J.3
Claesson-Welsh, L.4
-
36
-
-
79959373435
-
Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages
-
Park S.H., Park-Min K.H., Chen J., Hu X., Ivashkiv L.B. Tumor necrosis factor induces GSK3 kinase-mediated cross-tolerance to endotoxin in macrophages. Nat. Immunol. 2011, 12:607-615.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 607-615
-
-
Park, S.H.1
Park-Min, K.H.2
Chen, J.3
Hu, X.4
Ivashkiv, L.B.5
-
37
-
-
33750807672
-
Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory Tcells
-
Patton D.T., Garden O.A., Pearce W.P., Clough L.E., Monk C.R., Leung E., Rowan W.C., Sancho S., Walker L.S.K., Vanhaesebroeck B., Okkenhaug K. Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory Tcells. J.Immunol. 2006, 177:6598-6602.
-
(2006)
J.Immunol.
, vol.177
, pp. 6598-6602
-
-
Patton, D.T.1
Garden, O.A.2
Pearce, W.P.3
Clough, L.E.4
Monk, C.R.5
Leung, E.6
Rowan, W.C.7
Sancho, S.8
Walker, L.S.K.9
Vanhaesebroeck, B.10
Okkenhaug, K.11
-
39
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
-
Poltorak A., He X., Smirnova I., Liu M.Y., Van Huffel C., Du X., Birdwell D., Alejos E., Silva M., Galanos C., et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998, 282:2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
40
-
-
45549098562
-
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
-
Sauer S., Bruno L., Hertweck A., Finlay D., Leleu M., Spivakov M., Knight Z.A., Cobb B.S., Cantrell D., O'Connor E., et al. T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. Proc. Natl. Acad. Sci. USA 2008, 105:7797-7802.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 7797-7802
-
-
Sauer, S.1
Bruno, L.2
Hertweck, A.3
Finlay, D.4
Leleu, M.5
Spivakov, M.6
Knight, Z.A.7
Cobb, B.S.8
Cantrell, D.9
O'Connor, E.10
-
41
-
-
33645101274
-
MyD88-mediated stabilization of interferon-gamma-induced cytokine and chemokine mRNA
-
Sun D., Ding A. MyD88-mediated stabilization of interferon-gamma-induced cytokine and chemokine mRNA. Nat. Immunol. 2006, 7:375-381.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 375-381
-
-
Sun, D.1
Ding, A.2
-
42
-
-
52049095036
-
New insights into NF-kappaB regulation and function
-
Sun S.C., Ley S.C. New insights into NF-kappaB regulation and function. Trends Immunol. 2008, 29:469-478.
-
(2008)
Trends Immunol.
, vol.29
, pp. 469-478
-
-
Sun, S.C.1
Ley, S.C.2
-
43
-
-
80555154007
-
SOCS1 isessential for regulatory Tcell functions by preventing loss of Foxp3 expression as well as IFN-gamma and IL-17A production
-
Takahashi R., Nishimoto S., Muto G., Sekiya T., Tamiya T., Kimura A., Morita R., Asakawa M., Chinen T., Yoshimura A. SOCS1 isessential for regulatory Tcell functions by preventing loss of Foxp3 expression as well as IFN-gamma and IL-17A production. J.Exp. Med. 2011, 208:2055-2067.
-
(2011)
J.Exp. Med.
, vol.208
, pp. 2055-2067
-
-
Takahashi, R.1
Nishimoto, S.2
Muto, G.3
Sekiya, T.4
Tamiya, T.5
Kimura, A.6
Morita, R.7
Asakawa, M.8
Chinen, T.9
Yoshimura, A.10
-
44
-
-
0034733672
-
Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains
-
Takaoka A., Mitani Y., Suemori H., Sato M., Yokochi T., Noguchi S., Tanaka N., Taniguchi T. Cross talk between interferon-gamma and -alpha/beta signaling components in caveolar membrane domains. Science 2000, 288:2357-2360.
-
(2000)
Science
, vol.288
, pp. 2357-2360
-
-
Takaoka, A.1
Mitani, Y.2
Suemori, H.3
Sato, M.4
Yokochi, T.5
Noguchi, S.6
Tanaka, N.7
Taniguchi, T.8
-
45
-
-
36849058242
-
Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation
-
Tammela T., Saaristo A., Holopainen T., Lyytikkä J., Kotronen A., Pitkonen M., Abo-Ramadan U., Ylä-Herttuala S., Petrova T.V., Alitalo K. Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation. Nat. Med. 2007, 13:1458-1466.
-
(2007)
Nat. Med.
, vol.13
, pp. 1458-1466
-
-
Tammela, T.1
Saaristo, A.2
Holopainen, T.3
Lyytikkä, J.4
Kotronen, A.5
Pitkonen, M.6
Abo-Ramadan, U.7
Ylä-Herttuala, S.8
Petrova, T.V.9
Alitalo, K.10
-
46
-
-
74049125175
-
Phase 2 trial of eritoran tetrasodium (E5564), a toll-like receptor 4 antagonist, in patients with severe sepsis
-
Eritoran Sepsis Study Group
-
Tidswell M., Tillis W., Larosa S.P., Lynn M., Wittek A.E., Kao R., Wheeler J., Gogate J., Opal S.M. Phase 2 trial of eritoran tetrasodium (E5564), a toll-like receptor 4 antagonist, in patients with severe sepsis. Crit. Care Med. 2010, 38:72-83. Eritoran Sepsis Study Group.
-
(2010)
Crit. Care Med.
, vol.38
, pp. 72-83
-
-
Tidswell, M.1
Tillis, W.2
Larosa, S.P.3
Lynn, M.4
Wittek, A.E.5
Kao, R.6
Wheeler, J.7
Gogate, J.8
Opal, S.M.9
-
47
-
-
11444264653
-
Plasma vascular endothelial growth factor in severe sepsis
-
van der Flier M., van Leeuwen H.J., van Kessel K.P., Kimpen J.L., Hoepelman A.I., Geelen S.P. Plasma vascular endothelial growth factor in severe sepsis. Shock 2005, 23:35-38.
-
(2005)
Shock
, vol.23
, pp. 35-38
-
-
van der Flier, M.1
van Leeuwen, H.J.2
van Kessel, K.P.3
Kimpen, J.L.4
Hoepelman, A.I.5
Geelen, S.P.6
-
49
-
-
0038047587
-
Modulation of tissue Toll-like receptor 2 and 4 during the early phases of polymicrobial sepsis correlates with mortality
-
Williams D.L., Ha T., Li C., Kalbfleisch J.H., Schweitzer J., Vogt W., Browder I.W. Modulation of tissue Toll-like receptor 2 and 4 during the early phases of polymicrobial sepsis correlates with mortality. Crit. Care Med. 2003, 31:1808-1818.
-
(2003)
Crit. Care Med.
, vol.31
, pp. 1808-1818
-
-
Williams, D.L.1
Ha, T.2
Li, C.3
Kalbfleisch, J.H.4
Schweitzer, J.5
Vogt, W.6
Browder, I.W.7
-
50
-
-
33745021587
-
Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality
-
Yano K., Liaw P.C., Mullington J.M., Shih S.C., Okada H., Bodyak N., Kang P.M., Toltl L., Belikoff B., Buras J., et al. Vascular endothelial growth factor is an important determinant of sepsis morbidity and mortality. J.Exp. Med. 2006, 203:1447-1458.
-
(2006)
J.Exp. Med.
, vol.203
, pp. 1447-1458
-
-
Yano, K.1
Liaw, P.C.2
Mullington, J.M.3
Shih, S.C.4
Okada, H.5
Bodyak, N.6
Kang, P.M.7
Toltl, L.8
Belikoff, B.9
Buras, J.10
-
51
-
-
78649899926
-
VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis
-
Zhang L., Zhou F., Han W., Shen B., Luo J., Shibuya M., He Y. VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis. Cell Res. 2010, 20:1319-1331.
-
(2010)
Cell Res.
, vol.20
, pp. 1319-1331
-
-
Zhang, L.1
Zhou, F.2
Han, W.3
Shen, B.4
Luo, J.5
Shibuya, M.6
He, Y.7
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