Functional evolution of Erg potassium channel gating reveals an ancient origin for IKr

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 15, 2014, Pages 5712-5717

  Martinson, Alexandra S ^a   Van Rossum, Damian B ^a   Diatta, Fortunay H ^a   Layden, Michael J ^b   Rhodes, Sarah A ^a   Martindale, Mark Q ^b   Jegla, Timothy ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

Anopheles; CNBHD; PAS; Sei

Indexed keywords

POTASSIUM CHANNEL; POTASSIUM CHANNEL ERG; UNCLASSIFIED DRUG;

ACTION POTENTIAL; ARTICLE; BILATERIA; CAENORHABDITIS ELEGANS; CELL MEMBRANE; CHANNEL GATING; CNIDARIA; DEPOLARIZATION; DROSOPHILA; EVOLUTION; NEMATOSTELLA VECTENSIS; NONHUMAN; PARALOGY; PHENOTYPE; PHYLOGENY; PLACOZOA; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN QUATERNARY STRUCTURE; REPOLARIZATION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

ANOPHELES; CNBHD; PAS; SEI;

ACTION POTENTIALS; ANIMALS; BASE SEQUENCE; BAYES THEOREM; CAENORHABDITIS; CLONING, MOLECULAR; COMPUTATIONAL BIOLOGY; DAPHNIA; ETHER-A-GO-GO POTASSIUM CHANNELS; EVOLUTION, MOLECULAR; ION CHANNEL GATING; MODELS, BIOLOGICAL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; PATCH-CLAMP TECHNIQUES; PLACOZOA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEA ANEMONES; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY; XENOPUS;

EID: 84898790124     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1321716111     Document Type: Article

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