Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model

Journal of Comparative Neurology

Volumn 522, Issue 10, 2014, Pages 2319-2335

  Steele, John W ^a,b,h   Brautigam, Hannah ^b   Short, Jennifer A ^b   Sowa, Allison ^b   Shi, Mengxi ^b   Yadav, Aniruddha ^b   Weaver, Christina M ^c   Westaway, David ^d   Fraser, Paul E ^e   St George Hyslop, Peter H ^e,f   Gandy, Sam ^b,g   Hof, Patrick R ^b   Dickstein, Dara L ^b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c FRANKLIN AND MARSHALL COLLEGE   (United States)

^d UNIVERSITY OF ALBERTA   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^g VETERANS AFFAIRS MEDICAL CENTER   (United States)

^h Ambrx   (United States)

Author keywords

Amyloid beta; Dendritic pathology; Mouse model of dementia; Neuronal morphology; Spine pathology

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; NERVE PROTEIN;

ALZHEIMER DISEASE; AMYLOID PLAQUE; AMYLOIDOSIS; ANIMAL; ASSOCIATION; BRAIN; CELL COUNT; DENDRITE; DENDRITIC SPINE; DISEASE MODEL; FEAR; GENETICS; HIPPOCAMPUS; HUMAN; MALE; MEMORY DISORDER; METABOLISM; NERVE CELL; NERVE CELL PLASTICITY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOIDOSIS; ANIMALS; BRAIN; CELL COUNT; CUES; DENDRITES; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; FEAR; HIPPOCAMPUS; HUMANS; MALE; MEMORY DISORDERS; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; NEURONS; PLAQUE, AMYLOID;

EID: 84898678290     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.23536     Document Type: Article

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