Metabolic profiling reveals disorder of carbohydrate metabolism in mouse fibroblast cells induced by titanium dioxide nanoparticles

Journal of Applied Toxicology

Volumn 33, Issue 12, 2013, Pages 1442-1450

  Jin, Chengyu ^a,b   Liu, Yumin ^c   Sun, Limin ^a   Chen, Tianlu ^b   Zhang, Yinan ^b   Zhao, Aihua ^c   Wang, Xiaoyan ^c   Cristau, Melanie ^a   Wang, Kaisheng ^c   Jia, Wei ^c,d  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Chinese National Human Genome Center at Shanghai   (China)

^d UNIVERSITY OF NORTH CAROLINA AT GREENSBORO   (United States)

Author keywords

Carbohydrate metabolism; Cytotoxicity; L929 cells; Metabolomic strategy; TiO2 nanoparticles

Indexed keywords

2 METHYLENESUCCINATE; 2 OXOGLUTARIC ACID; 3 PHOSPHOGLYCERIC ACID; ARABINITOL; CITRIC ACID; DIHYDROXYACETONE PHOSPHATE; ETHANOLAMINE; FRUCTOSE; GALACTOSE; GLUCOSE; GLUCOSE 6 PHOSPHATE; GLYCEROPHOSPHATE; INOSITOL; LACTIC ACID; MALTOSE; MANNITOL; MANNOSE; NANOPARTICLE; PHOSPHATE; PYRUVIC ACID; RIBOSE 5 PHOSPHATE; SORBITOL; SORBOSE; SUCCINIC ACID; SUCCINIC ACID DERIVATIVE; TITANIUM DIOXIDE; TREHALOSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRESS; CONTROLLED STUDY; CYTOTOXICITY; DISCRIMINANT ANALYSIS; DISORDERS OF CARBOHYDRATE METABOLISM; ENERGY METABOLISM; FIBROBLAST; GAS CHROMATOGRAPHY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; METABOLITE; METABOLOMICS; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL;

CARBOHYDRATE METABOLISM; CYTOTOXICITY; L929 CELLS; METABOLOMIC STRATEGY; TIO2 NANOPARTICLES;

ANIMALS; CARBOHYDRATE METABOLISM; CELL CULTURE TECHNIQUES; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LEAST-SQUARES ANALYSIS; METABOLOME; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PRINCIPAL COMPONENT ANALYSIS; TITANIUM;

EID: 84886096552     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2808     Document Type: Article

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