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Volumn 9, Issue 4, 2014, Pages

Proteolysis of the human DNA polymerase delta smallest subunit p12 by μ-calpain in calcium-triggered apoptotic hela cells

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CALCIUM ION; CALPAIN 1; CASPASE 3; CYCLINE; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE DELTA 3; DNA DIRECTED DNA POLYMERASE DELTA 4; DNA DIRECTED DNA POLYMERASE DELTA P12 SUBUNIT; DNA DIRECTED DNA POLYMERASE DELTA P125 SUBUNIT; DNA DIRECTED DNA POLYMERASE DELTA P50 SUBUNIT; DNA DIRECTED DNA POLYMERASE DELTA P68 SUBUNIT; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG; CALCIUM; CALPAIN; DNA DIRECTED DNA POLYMERASE GAMMA; DNA POLYMERASE DELTA P12 SUBUNIT, HUMAN; MU-CALPAIN;

EID: 84898605402     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093642     Document Type: Article
Times cited : (8)

References (55)
  • 1
    • 84861858876 scopus 로고    scopus 로고
    • Structure of monoubiquitinated PCNA: Implications for DNA polymerase switching and Okazaki fragment maturation
    • Zhang Z, Zhang S, Lin SH, Wang X, Wu L, et al. (2012) Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation. Cell Cycle 11: 2128-2136.
    • (2012) Cell Cycle , vol.11 , pp. 2128-2136
    • Zhang, Z.1    Zhang, S.2    Lin, S.H.3    Wang, X.4    Wu, L.5
  • 2
    • 79960336112 scopus 로고    scopus 로고
    • Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor
    • Zhou Y, Chen H, Li X, Wang Y, Chen K, et al. (2011) Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. PLoS One 6: e22224.
    • (2011) PLoS One , vol.6
    • Zhou, Y.1    Chen, H.2    Li, X.3    Wang, Y.4    Chen, K.5
  • 3
    • 84863012802 scopus 로고    scopus 로고
    • Phosphorylation of the p68 subunit of Pol delta acts as a molecular switch to regulate its interaction with PCNA
    • Rahmeh AA, Zhou Y, Xie B, Li H, Lee EY, et al. (2012) Phosphorylation of the p68 subunit of Pol delta acts as a molecular switch to regulate its interaction with PCNA. Biochemistry 51: 416-424.
    • (2012) Biochemistry , vol.51 , pp. 416-424
    • Rahmeh, A.A.1    Zhou, Y.2    Xie, B.3    Li, H.4    Lee, E.Y.5
  • 4
    • 77951690551 scopus 로고    scopus 로고
    • The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis
    • Meng X, Zhou Y, Lee EY, Lee MY, Frick DN (2010) The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis. Biochemistry 49: 3545-3554.
    • (2010) Biochemistry , vol.49 , pp. 3545-3554
    • Meng, X.1    Zhou, Y.2    Lee, E.Y.3    Lee, M.Y.4    Frick, D.N.5
  • 5
    • 41149094512 scopus 로고    scopus 로고
    • Regulation of DNA repair throughout the cell cycle
    • DOI 10.1038/nrm2351, PII NRM2351
    • Branzei D, Foiani M (2008) Regulation of DNA repair throughout the cell cycle. Nat Rev Mol Cell Biol 9: 297-308. (Pubitemid 351430844)
    • (2008) Nature Reviews Molecular Cell Biology , vol.9 , Issue.4 , pp. 297-308
    • Branzei, D.1    Foiani, M.2
  • 6
    • 3943107573 scopus 로고    scopus 로고
    • Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
    • DOI 10.1146/annurev.biochem.73.011303.073723
    • Sancar A, Lindsey-Boltz LA, Unsal-Kacmaz K, Linn S (2004) Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem 73: 39-85. (Pubitemid 39050363)
    • (2004) Annual Review of Biochemistry , vol.73 , pp. 39-85
    • Sancar, A.1    Lindsey-Boltz, L.A.2    Unsal-Kacmaz, K.3    Linn, S.4
  • 7
    • 34447558592 scopus 로고    scopus 로고
    • A novel DNA damage response: Rapid degradation of the p12 subunit of DNA polymerase δ
    • DOI 10.1074/jbc.M610356200
    • Zhang S, Zhou Y, Trusa S, Meng X, Lee EY, et al. (2007) A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta. J Biol Chem 282: 15330-15340. (Pubitemid 47093258)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.21 , pp. 15330-15340
    • Zhang, S.1    Zhou, Y.2    Trusa, S.3    Meng, X.4    Lee, E.Y.C.5    Lee, M.Y.W.T.6
  • 8
    • 59649103417 scopus 로고    scopus 로고
    • DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers
    • Meng X, Zhou Y, Zhang S, Lee EY, Frick DN, et al. (2009) DNA damage alters DNA polymerase delta to a form that exhibits increased discrimination against modified template bases and mismatched primers. Nucleic Acids Res 37: 647-657.
    • (2009) Nucleic Acids Res , vol.37 , pp. 647-657
    • Meng, X.1    Zhou, Y.2    Zhang, S.3    Lee, E.Y.4    Frick, D.N.5
  • 9
    • 84864573459 scopus 로고    scopus 로고
    • Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage
    • Chea J, Zhang S, Zhao H, Zhang Z, Lee EY, et al. (2012) Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage. Cell Cycle 11: 2885-2895.
    • (2012) Cell Cycle , vol.11 , pp. 2885-2895
    • Chea, J.1    Zhang, S.2    Zhao, H.3    Zhang, Z.4    Lee, E.Y.5
  • 11
    • 79959906411 scopus 로고    scopus 로고
    • Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites
    • Andersen PL, Xu F, Ziola B, McGregor WG, Xiao W (2011) Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites. Mol Biol Cell 22: 2373-2383.
    • (2011) Mol Biol Cell , vol.22 , pp. 2373-2383
    • Andersen, P.L.1    Xu, F.2    Ziola, B.3    McGregor, W.G.4    Xiao, W.5
  • 12
    • 80052754015 scopus 로고    scopus 로고
    • Roles of sequential ubiquitination of PCNA in DNA-damage tolerance
    • Zhang W, Qin Z, Zhang X, Xiao W (2011) Roles of sequential ubiquitination of PCNA in DNA-damage tolerance. FEBS Lett 585: 2786-2794.
    • (2011) FEBS Lett , vol.585 , pp. 2786-2794
    • Zhang, W.1    Qin, Z.2    Zhang, X.3    Xiao, W.4
  • 13
    • 84857411787 scopus 로고    scopus 로고
    • Y-family DNA polymerases and their role in tolerance of cellular DNA damage
    • Sale JE, Lehmann AR, Woodgate R (2012) Y-family DNA polymerases and their role in tolerance of cellular DNA damage. Nat Rev Mol Cell Biol 13: 141-152.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 141-152
    • Sale, J.E.1    Lehmann, A.R.2    Woodgate, R.3
  • 14
    • 84873298852 scopus 로고    scopus 로고
    • Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase delta for degradation in response to DNA damage
    • Zhang S, Zhou Y, Sarkeshik A, Yates JR, 3rd, Thomson TM, et al. (2013) Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase delta for degradation in response to DNA damage. J Biol Chem 288: 2941-2950.
    • (2013) J Biol Chem , vol.288 , pp. 2941-2950
    • Zhang, S.1    Zhou, Y.2    Sarkeshik, A.3    Yates, J.R.4    Thomson, T.M.5
  • 15
    • 84885660479 scopus 로고    scopus 로고
    • A novel function of CRL4(Cdt2): Regulation of the subunit structure of DNA polymerase delta in response to DNA damage and during the S phase
    • Zhang S, Zhao H, Darzynkiewicz Z, Zhou P, Zhang Z, et al. (2013) A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase delta in response to DNA damage and during the S phase. J Biol Chem 288: 29550-29561.
    • (2013) J Biol Chem , vol.288 , pp. 29550-29561
    • Zhang, S.1    Zhao, H.2    Darzynkiewicz, Z.3    Zhou, P.4    Zhang, Z.5
  • 16
    • 84862502745 scopus 로고    scopus 로고
    • Characterization of human DNA polymerase delta and its subassemblies reconstituted by expression in the MultiBac system
    • Zhou Y, Meng X, Zhang S, Lee EY, Lee MY (2012) Characterization of human DNA polymerase delta and its subassemblies reconstituted by expression in the MultiBac system. PLoS One 7: e39156.
    • (2012) PLoS One , vol.7
    • Zhou, Y.1    Meng, X.2    Zhang, S.3    Lee, E.Y.4    Lee, M.Y.5
  • 20
    • 0030593657 scopus 로고    scopus 로고
    • Autolysis of human erythrocyte calpain produces two active enzyme forms with different cell localization
    • DOI 10.1016/0014-5793(96)00775-2
    • Michetti M, Salamino F, Tedesco I, Averna M, Minafra R, et al. (1996) Autolysis of human erythrocyte calpain produces two active enzyme forms with different cell localization. FEBS Lett 392: 11-15. (Pubitemid 26268322)
    • (1996) FEBS Letters , vol.392 , Issue.1 , pp. 11-15
    • Michetti, M.1    Salamino, F.2    Tedesco, I.3    Averna, M.4    Minafra, R.5    Melloni, E.6    Pontremoli, S.7
  • 21
    • 0023091938 scopus 로고
    • Functional identity of proliferating cell nuclear antigen and a DNA polymerase-δ auxiliary protein
    • DOI 10.1038/326517a0
    • Prelich G, Tan CK, Kostura M, Mathews MB, So AG, et al. (1987) Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein. Nature 326: 517-520. (Pubitemid 17055499)
    • (1987) Nature , vol.326 , Issue.6112 , pp. 517-520
    • Prelich, G.1    Tan, C.-K.2    Kostura, M.3
  • 22
    • 0030814675 scopus 로고    scopus 로고
    • Caspases: Killer proteases
    • DOI 10.1016/S0968-0004(97)01085-2, PII S0968000497010852
    • Nicholson DW, Thornberry NA (1997) Caspases: killer proteases. Trends Biochem Sci 22: 299-306. (Pubitemid 27327087)
    • (1997) Trends in Biochemical Sciences , vol.22 , Issue.8 , pp. 299-306
    • Nicholson, D.W.1    Thornberry, N.A.2
  • 23
    • 0030931876 scopus 로고    scopus 로고
    • Caspases: The executioners of apoptosis
    • Cohen GM (1997) Caspases: the executioners of apoptosis. Biochem J 326 (Pt 1): 1-16. (Pubitemid 27386911)
    • (1997) Biochemical Journal , vol.326 , Issue.1 , pp. 1-16
    • Cohen, G.M.1
  • 24
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
    • Kaufmann SH, Desnoyers S, Ottaviano Y, Davidson NE, Poirier GG (1993) Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res 53: 3976-3985. (Pubitemid 23267698)
    • (1993) Cancer Research , vol.53 , Issue.17 , pp. 3976-3985
    • Kaufmann, S.H.1    Desnoyers, S.2    Ottaviano, Y.3    Davidson, N.E.4    Poirier, G.G.5
  • 25
    • 0030023846 scopus 로고    scopus 로고
    • Cleavage of retinoblastoma protein during apoptosis: An interleukin 1 beta-converting enzyme-like protease as candidate
    • An B, Dou QP (1996) Cleavage of retinoblastoma protein during apoptosis: an interleukin 1 beta-converting enzyme-like protease as candidate. Cancer Res 56: 438-442.
    • (1996) Cancer Res , vol.56 , pp. 438-442
    • An, B.1    Dou, Q.P.2
  • 26
    • 0029046470 scopus 로고
    • Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution
    • Lazebnik YA, Takahashi A, Moir RD, Goldman RD, Poirier GG, et al. (1995) Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc Natl Acad Sci U S A 92: 9042-9046.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 9042-9046
    • Lazebnik, Y.A.1    Takahashi, A.2    Moir, R.D.3    Goldman, R.D.4    Poirier, G.G.5
  • 28
    • 0030916417 scopus 로고    scopus 로고
    • DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis
    • Liu X, Zou H, Slaughter C, Wang X (1997) DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 89: 175-184. (Pubitemid 27199890)
    • (1997) Cell , vol.89 , Issue.2 , pp. 175-184
    • Liu, X.1    Zou, H.2    Slaughter, C.3    Wang, X.4
  • 30
    • 0033832629 scopus 로고    scopus 로고
    • Noncaspase proteases in apoptosis
    • Johnson DE (2000) Noncaspase proteases in apoptosis. Leukemia 14: 1695-1703.
    • (2000) Leukemia , vol.14 , pp. 1695-1703
    • Johnson, D.E.1
  • 32
    • 26844461079 scopus 로고    scopus 로고
    • Digestive versus regulatory proteases: On calpain action in vivo
    • DOI 10.1515/BC.2005.071
    • Friedrich P, Bozoky Z (2005) Digestive versus regulatory proteases: on calpain action in vivo. Biol Chem 386: 609-612. (Pubitemid 41448163)
    • (2005) Biological Chemistry , vol.386 , Issue.7 , pp. 609-612
    • Friedrich, P.1    Bozoky, Z.2
  • 33
    • 0034326919 scopus 로고    scopus 로고
    • Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis
    • Liu W, Linn S (2000) Proteolysis of the human DNA polymerase epsilon catalytic subunit by caspase-3 and calpain specifically during apoptosis. Nucleic Acids Res 28: 4180-4188.
    • (2000) Nucleic Acids Res , vol.28 , pp. 4180-4188
    • Liu, W.1    Linn, S.2
  • 34
    • 28844491633 scopus 로고    scopus 로고
    • Determination of peptide substrate specificity for μ-calpain by a peptide library-based approach: The importance of primed side interactions
    • DOI 10.1074/jbc.M506870200
    • Cuerrier D, Moldoveanu T, Davies PL (2005) Determination of peptide substrate specificity for mu-calpain by a peptide library-based approach: the importance of primed side interactions. J Biol Chem 280: 40632-40641. (Pubitemid 41780554)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.49 , pp. 40632-40641
    • Cuerrier, D.1    Moldoveanu, T.2    Davies, P.L.3
  • 37
    • 79955780941 scopus 로고    scopus 로고
    • Calpain cleavage prediction using multiple kernel learning
    • DuVerle DA, Ono Y, Sorimachi H, Mamitsuka H (2011) Calpain cleavage prediction using multiple kernel learning. PLoS One 6: e19035.
    • (2011) PLoS One , vol.6
    • Duverle, D.A.1    Ono, Y.2    Sorimachi, H.3    Mamitsuka, H.4
  • 38
    • 27844595293 scopus 로고    scopus 로고
    • Caspase and calpain function in cell death: Bridging the gap between apoptosis and necrosis
    • DOI 10.1258/000456305774538238
    • Harwood SM, Yaqoob MM, Allen DA (2005) Caspase and calpain function in cell death: bridging the gap between apoptosis and necrosis. Ann Clin Biochem 42: 415-431. (Pubitemid 41640512)
    • (2005) Annals of Clinical Biochemistry , vol.42 , Issue.6 , pp. 415-431
    • Harwood, S.M.1    Yaqoob, M.M.2    Allen, D.A.3
  • 39
    • 0034723310 scopus 로고    scopus 로고
    • Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway
    • DOI 10.1074/jbc.275.4.2390
    • Glading A, Chang P, Lauffenburger DA, Wells A (2000) Epidermal growth factor receptor activation of calpain is required for fibroblast motility and occurs via an ERK/MAP kinase signaling pathway. J Biol Chem 275: 2390-2398. (Pubitemid 30081997)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.4 , pp. 2390-2398
    • Glading, A.1    Chang, P.2    Lauffenburger, D.A.3    Wells, A.4
  • 40
    • 0035968342 scopus 로고    scopus 로고
    • Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling
    • Glading A, Uberall F, Keyse SM, Lauffenburger DA, Wells A (2001) Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling. J Biol Chem 276: 23341-23348.
    • (2001) J Biol Chem , vol.276 , pp. 23341-23348
    • Glading, A.1    Uberall, F.2    Keyse, S.M.3    Lauffenburger, D.A.4    Wells, A.5
  • 41
    • 1542344328 scopus 로고    scopus 로고
    • Epidermal Growth Factor Activates m-Calpain (Calpain II), at Least in Part, by Extracellular Signal-Regulated Kinase-Mediated Phosphorylation
    • DOI 10.1128/MCB.24.6.2499-2512.2004
    • Glading A, Bodnar RJ, Reynolds IJ, Shiraha H, Satish L, et al. (2004) Epidermal growth factor activates m-calpain (calpain II), at least in part, by extracellular signal-regulated kinase-mediated phosphorylation. Mol Cell Biol 24: 2499-2512. (Pubitemid 38326004)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.6 , pp. 2499-2512
    • Glading, A.1    Bodnar, R.J.2    Reynolds, I.J.3    Shiraha, H.4    Satish, L.5    Potter, D.A.6    Blair, H.C.7    Wells, A.8
  • 42
    • 80054782313 scopus 로고    scopus 로고
    • Role of calpain in apoptosis
    • Momeni HR (2011) Role of calpain in apoptosis. Cell J 13: 65-72.
    • (2011) Cell J , vol.13 , pp. 65-72
    • Momeni, H.R.1
  • 43
    • 0037068455 scopus 로고    scopus 로고
    • RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO
    • DOI 10.1038/nature00991
    • Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature 419: 135-141. (Pubitemid 35025438)
    • (2002) Nature , vol.419 , Issue.6903 , pp. 135-141
    • Hoege, C.1    Pfander, B.2    Moldovan, G.-L.3    Pyrowolakis, G.4    Jentsch, S.5
  • 44
    • 33745212873 scopus 로고    scopus 로고
    • Localization of Y-family polymerases and the DNA polymerase switch in mammalian cells
    • Kannouche P, Lehmann A (2006) Localization of Y-family polymerases and the DNA polymerase switch in mammalian cells. Methods Enzymol 408: 407-415.
    • (2006) Methods Enzymol , vol.408 , pp. 407-415
    • Kannouche, P.1    Lehmann, A.2
  • 47
    • 33748087835 scopus 로고    scopus 로고
    • Involvement of calpain activation in neurodegenerative processes
    • DOI 10.1111/j.1527-3458.2006.00135.x
    • Camins A, Verdaguer E, Folch J, Pallas M (2006) Involvement of calpain activation in neurodegenerative processes. CNS Drug Rev 12: 135-148. (Pubitemid 44300381)
    • (2006) CNS Drug Reviews , vol.12 , Issue.2 , pp. 135-148
    • Camins, A.1    Verdaguer, E.2    Folch, J.3    Pallas, M.4
  • 49
    • 33747884339 scopus 로고    scopus 로고
    • DNA damage-induced cell death by apoptosis
    • DOI 10.1016/j.molmed.2006.07.007, PII S1471491406001687
    • Roos WP, Kaina B (2006) DNA damage-induced cell death by apoptosis. Trends Mol Med 12: 440-450. (Pubitemid 44291571)
    • (2006) Trends in Molecular Medicine , vol.12 , Issue.9 , pp. 440-450
    • Roos, W.P.1    Kaina, B.2
  • 50
    • 0642345198 scopus 로고    scopus 로고
    • DNA damage-triggered apoptosis: Critical role of DNA repair, double-strand breaks, cell proliferation and signaling
    • DOI 10.1016/S0006-2952(03)00510-0, PII S0006295203005100
    • Kaina B (2003) DNA damage-triggered apoptosis: critical role of DNA repair, double-strand breaks, cell proliferation and signaling. Biochem Pharmacol 66: 1547-1554. (Pubitemid 38373345)
    • (2003) Biochemical Pharmacology , vol.66 , Issue.8 , pp. 1547-1554
    • Kaina, B.1
  • 51
    • 33644854484 scopus 로고    scopus 로고
    • Rho GTPases: Promising cellular targets for novel anticancer drugs
    • Fritz G, Kaina B (2006) Rho GTPases: promising cellular targets for novel anticancer drugs. Curr Cancer Drug Targets 6: 1-14.
    • (2006) Curr Cancer Drug Targets , vol.6 , pp. 1-14
    • Fritz, G.1    Kaina, B.2
  • 52
    • 84872369181 scopus 로고    scopus 로고
    • Activation of an apoptotic signal transduction pathway involved in the upregulation of calpain and apoptosis-inducing factor in aldosterone-induced primary cultured cardiomyocytes
    • Xiao T, Zhang Y, Wang Y, Xu Y, Yu Z, et al. (2013) Activation of an apoptotic signal transduction pathway involved in the upregulation of calpain and apoptosis-inducing factor in aldosterone-induced primary cultured cardiomyocytes. Food Chem Toxicol 53: 364-370.
    • (2013) Food Chem Toxicol , vol.53 , pp. 364-370
    • Xiao, T.1    Zhang, Y.2    Wang, Y.3    Xu, Y.4    Yu, Z.5
  • 53
    • 80355136489 scopus 로고    scopus 로고
    • P50, the small subunit of DNA polymerase delta, is required for mediation of the interaction of polymerase delta subassemblies with PCNA
    • Wang Y, Zhang Q, Chen H, Li X, Mai W, et al. (2011) P50, the small subunit of DNA polymerase delta, is required for mediation of the interaction of polymerase delta subassemblies with PCNA. PLoS One 6: e27092.
    • (2011) PLoS One , vol.6
    • Wang, Y.1    Zhang, Q.2    Chen, H.3    Li, X.4    Mai, W.5
  • 55
    • 0037040170 scopus 로고    scopus 로고
    • Reconstitution of human DNA polymerase δ using recombinant baculoviruses: The p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme
    • DOI 10.1074/jbc.M109684200
    • Podust VN, Chang LS, Ott R, Dianov GL, Fanning E (2002) Reconstitution of human DNA polymerase delta using recombinant baculoviruses: the p12 subunit potentiates DNA polymerizing activity of the four-subunit enzyme. J Biol Chem 277: 3894-3901. (Pubitemid 34968641)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.6 , pp. 3894-3901
    • Podust, V.N.1    Chang, L.-S.2    Ott, R.3    Dianov, G.L.4    Fanning, E.5


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