Comprehensive evaluation of layer separation tendency of novel three-layered tablets with geometric and mechanical properties

International Journal of Pharmaceutics

Volumn 465, Issue 1-2, 2014, Pages 347-359

  Choi, Du Hyung ^a   Lim, Dae Gon ^a   Son, Hyung Min ^a   Jeong, Seong Hoon ^a  

^a Dongguk University   (South Korea)

Author keywords

Geometric tablet; Layer separation; Multi layered tablet; Physical properties; Porosity

Indexed keywords

EXCIPIENT; HYDROXYPROPYLMETHYLCELLULOSE; MACROGOL; MACROGOL 6000; MANNITOL; POLYMER; TAMSULOSIN; DELAYED RELEASE FORMULATION; POWDER; SULFONAMIDE; TABLET; WATER;

ADHESION; ARTICLE; CONTROLLED DRUG RELEASE; DRUG RELEASE; DRUG SCREENING; DRUG SOLUBILITY; IN VITRO STUDY; MATRIX TABLET; MULTI LAYERED MATRIX TABLET; POWDER FLOW; PRIORITY JOURNAL; SOLUBILIZATION; TABLET COMPRESSION; TABLET FORMULATION; TABLET MANUFACTURE; TABLET POROSITY; TABLET PROPERTY; TABLET THICKNESS; WATER ABSORPTION; WATER TRANSPORT; ANALYZER; AQUEOUS SOLUTION; CORRELATIONAL STUDY; DRUG STORAGE; EVALUATION STUDY; GEOMETRY; PHASE SEPARATION; PHYSICAL CHEMISTRY; POWDER; TEXTURE ANALYZER; ABSORPTION; CHEMISTRY; COMPARATIVE STUDY; DELAYED RELEASE FORMULATION; KINETICS; MEDICINAL CHEMISTRY; PHARMACEUTICS; POROSITY; PROCEDURES; SOLUBILITY; TABLET;

ABSORPTION, PHYSICOCHEMICAL; ADHESIVENESS; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; EXCIPIENTS; KINETICS; POROSITY; POWDERS; SOLUBILITY; SULFONAMIDES; TABLETS; TECHNOLOGY, PHARMACEUTICAL; WATER;

EID: 84898600693     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.02.014     Document Type: Article

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