A novel approach for using dielectric spectroscopy to predict viable cell volume (VCV) in early process development

Biotechnology Progress

Volumn 30, Issue 2, 2014, Pages 479-487

  Downey, Brandon J ^a   Graham, Lisa J ^a   Breit, Jeffrey F ^a   Glutting, Nathaniel K ^a  

^a Bend Research Incorporated   (United States)

Author keywords

Biomass probe; Capacitance; Dielectric spectroscopy; Frequency scanning; Mammalian CHO; Permittivity; Process control; Viable cell volume (VCV)

Indexed keywords

CAPACITANCE; CELL CULTURE; DIELECTRIC SPECTROSCOPY; DISPERSIONS; FORECASTING; MAMMALS; NONINVASIVE MEDICAL PROCEDURES; PERMITTIVITY; PERMITTIVITY MEASUREMENT; PROBES; PROCESS CONTROL; SCANNING;

COMMERCIAL AVAILABILITY; DIELECTRIC FREQUENCIES; FREQUENCY SCANNING; MAMMALIAN CELL CULTURE; MAMMALIAN CHO; PROCESS DEVELOPMENT; TECHNOLOGICAL CHALLENGES; VIABLE CELLS;

CELLS;

MAMMALIA;

ANIMAL; BIOMASS; BIOREACTOR; BIOTECHNOLOGY; CELL SHAPE; CELL SIZE; CELL SURVIVAL; CHO CELL LINE; CRICETULUS; CULTURE TECHNIQUE; ELECTROCHEMICAL IMPEDANCE SPECTROSCOPY; FLOW CYTOMETRY; HAMSTER; PROCEDURES;

ANIMALS; BIOMASS; BIOREACTORS; BIOTECHNOLOGY; CELL CULTURE TECHNIQUES; CELL SHAPE; CELL SIZE; CELL SURVIVAL; CHO CELLS; CRICETINAE; CRICETULUS; DIELECTRIC SPECTROSCOPY; FLOW CYTOMETRY;

EID: 84898549495     PISSN: 87567938     EISSN: 15206033     Source Type: Journal    
DOI: 10.1002/btpr.1845     Document Type: Article

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