Targeting xCT, a cystine-glutamate transporter induces apoptosis and tumor regression for KSHV/HIV-associated lymphoma

Journal of Hematology and Oncology

Volumn 7, Issue 1, 2014, Pages

  Dai, Lu ^a,b   Cao, Yueyu ^a   Chen, Yihan ^a   Parsons, Chris ^b   Qin, Zhiqiang ^a,b  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Herpesvirus; KSHV; Lymphoma; xCT

Indexed keywords

AMINO ACID TRANSPORTER; CASPASE; CYSTINE GLUTAMATE TRANSPORTER; GLUTAMATE TRANSPORTER; GLUTATHIONE; REACTIVE OXYGEN METABOLITE; SALAZOSULFAPYRIDINE; UNCLASSIFIED DRUG; CYSTINE; GLUTAMIC ACID DERIVATIVE; SLC7A11 PROTEIN, HUMAN; VIRUS PROTEIN;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CHEMOTHERAPY; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; GROWTH DISORDER; HERPES VIRUS; HIV ASSOCIATED LYMPHOMA; HUMAN; HUMAN CELL; IN VIVO STUDY; KAPOSI SARCOMA; LYMPHOMA; MORTALITY; PATHOGENESIS; TUMOR GROWTH; TUMOR REGRESSION; VIRUS GENE; XENOGRAFT; ANIMAL; B CELL LYMPHOMA; GENETIC TRANSFECTION; GENETICS; HUMAN HERPESVIRUS 8; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; ISOLATION AND PURIFICATION; MALE; METABOLISM; NONOBESE DIABETIC MOUSE; SCID MOUSE; SIGNAL TRANSDUCTION; VIROLOGY;

AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; APOPTOSIS; CYSTINE; GLUTAMATES; HERPESVIRUS 8, HUMAN; HIV INFECTIONS; HUMANS; LYMPHOMA, AIDS-RELATED; MALE; MICE, INBRED NOD; MICE, SCID; SARCOMA, KAPOSI; SIGNAL TRANSDUCTION; TRANSFECTION; VIRAL PROTEINS;

EID: 84898543118     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/1756-8722-7-30     Document Type: Article

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