Upregulation of xCT by KSHV-encoded microRNAs facilitates KSHV dissemination and persistence in an environment of oxidative stress

PLoS Pathogens

Volumn 6, Issue 1, 2010, Pages

  Qin, Zhiqiang ^a,b   Freitas, Eduardo ^a   Sullivan, Roger ^a   Mohan, Sarumathi ^a   Bacelieri, Rocky ^a   Branch, Drake ^a   Romano, Margaret ^a   Kearney, Patricia ^a   Oates, Jim ^a,c   Plaisance, Karlie ^d   Renne, Rolf ^d   Kaleeba, Johnan ^e   Parsons, Chris ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^c RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

^e Uniformed Services University of the Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSPORTER; MICRORNA; REACTIVE NITROGEN SPECIES; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BACH 1; UNCLASSIFIED DRUG; BACH1 PROTEIN, MOUSE; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; SLC7A11 PROTEIN, MOUSE;

ANIMAL CELL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; GENE TRANSFER; GENETIC CODE; HERPES VIRUS INFECTION; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 8; HUMAN TISSUE; INFECTION SENSITIVITY; KAPOSI SARCOMA; MACROPHAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PERSISTENT VIRUS INFECTION; PROMOTER REGION; UPREGULATION; VIRUS CELL INTERACTION; VIRUS VIRULENCE; ANIMAL; BIOSYNTHESIS; CANCER STAGING; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSFECTION; GENETICS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; POLYMERASE CHAIN REACTION; VIROLOGY;

HUMAN HERPESVIRUS 8;

AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL LINE; ENDOTHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HERPESVIRUS 8, HUMAN; HUMANS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MACROPHAGES; MICE; MICRORNAS; NEOPLASM STAGING; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; REACTIVE NITROGEN SPECIES; SARCOMA, KAPOSI; TRANSFECTION; UP-REGULATION;

EID: 77649207029     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000742     Document Type: Article

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