A critical role of autophagy in antileukemia/lymphoma effects of APO866, an inhibitor of NAD biosynthesis

Autophagy

Volumn 10, Issue 4, 2014, Pages 603-617

  Ginet, Vanessa ^a   Puyal, Julien ^a   Rummel, Coralie ^a   Aubry, Dominique ^b   Breton, Caroline ^b   Cloux, Anne Julie ^b   Majjigapu, Somi R ^c   Sordat, Bernard ^c   Vogel, Pierre ^c   Bruzzone, Santina ^d   Nencioni, Alessio ^e   Duchosal, Michel A ^b   Nahimana, Aimable ^b  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^c EPFL   (Switzerland)

^d UNIVERSITY OF GENOA   (Italy)

^e UNIVERSITY OF GENOA   (Italy)

Author keywords

APO866; ATG; Autophagy; CATALASE; Leukemia; Lymphoma; NAD; ROS; Therapy

Indexed keywords

AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; CASPASE 3; CATALASE; DAPORINAD; NICOTINAMIDE ADENINE DINUCLEOTIDE; PROTEIN; PROTEIN P62; REACTIVE OXYGEN METABOLITE; SQSTM1 PROTEIN; UNCLASSIFIED DRUG; ACRYLAMIDE DERIVATIVE; CASP3 PROTEIN, HUMAN; N-(4-(1-BENZOYLPIPERIDIN-4-YL)BUTYL)-3-(PYRIDIN-3-YL)ACRYLAMIDE; PIPERIDINE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BIOSYNTHESIS; CELL DEATH; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ENZYME ACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; LEUKEMIA; LYMPHOMA CELL; PROTEIN DEGRADATION; ANTAGONISTS AND INHIBITORS; APOPTOSIS; DRUG EFFECTS; LYMPHOMA; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ACRYLAMIDES; APOPTOSIS; AUTOPHAGY; CASPASE 3; CELL LINE, TUMOR; HUMANS; LEUKEMIA; LYMPHOMA; NAD; PIPERIDINES; REACTIVE OXYGEN SPECIES;

EID: 84898464304     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.27722     Document Type: Article

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