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Volumn 424, Issue 3, 2012, Pages 371-377

Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cells

Author keywords

Acetylation; NAMPT and FK866; P53; SV 40; T antigen

Indexed keywords

DAPORINAD; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PROTEIN P53;

EID: 84864777092     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.06.075     Document Type: Article
Times cited : (28)

References (24)
  • 2
    • 27944459717 scopus 로고    scopus 로고
    • SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation
    • Ahuja D., Saenz-Robles M.T., Pipas J.M. SV40 large T antigen targets multiple cellular pathways to elicit cellular transformation. Oncogene 2005, 24:7729-7745.
    • (2005) Oncogene , vol.24 , pp. 7729-7745
    • Ahuja, D.1    Saenz-Robles, M.T.2    Pipas, J.M.3
  • 3
    • 0026686753 scopus 로고
    • Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53
    • Bargonetti J., Reynisdottir I., Friedman P.N., Prives C. Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53. Genes Dev. 1992, 6:1886-1898.
    • (1992) Genes Dev. , vol.6 , pp. 1886-1898
    • Bargonetti, J.1    Reynisdottir, I.2    Friedman, P.N.3    Prives, C.4
  • 4
    • 33748250439 scopus 로고    scopus 로고
    • Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor
    • Lilyestrom W., Klein M.G., Zhang R., Joachimiak A., Chen X.S. Crystal structure of SV40 large T-antigen bound to p53: interplay between a viral oncoprotein and a cellular tumor suppressor. Genes Dev. 2006, 20:2373-2382.
    • (2006) Genes Dev. , vol.20 , pp. 2373-2382
    • Lilyestrom, W.1    Klein, M.G.2    Zhang, R.3    Joachimiak, A.4    Chen, X.S.5
  • 5
    • 0142216442 scopus 로고    scopus 로고
    • High throughput testing of the SV40 Large T antigen binding to cellular p53 identifies putative drugs for the treatment of SV40-related cancers
    • Carbone M., Rudzinski J., Bocchetta M. High throughput testing of the SV40 Large T antigen binding to cellular p53 identifies putative drugs for the treatment of SV40-related cancers. Virology 2003, 315:409-414.
    • (2003) Virology , vol.315 , pp. 409-414
    • Carbone, M.1    Rudzinski, J.2    Bocchetta, M.3
  • 6
    • 0022730596 scopus 로고
    • Evidence for free and metabolically stable p53 protein in nuclear subfractions of simian virus 40-transformed cells
    • Deppert W., Haug M. Evidence for free and metabolically stable p53 protein in nuclear subfractions of simian virus 40-transformed cells. Mol. Cell. Biol. 1986, 6:2233-2240.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2233-2240
    • Deppert, W.1    Haug, M.2
  • 7
    • 77955858336 scopus 로고    scopus 로고
    • Posttranslational modification of p53: cooperative integrators of function
    • Meek D.W., Anderson C.W. Posttranslational modification of p53: cooperative integrators of function. Cold Spring Harb. Perspect Biol. 2009, 1(6):a000950.
    • (2009) Cold Spring Harb. Perspect Biol. , vol.1 , Issue.6
    • Meek, D.W.1    Anderson, C.W.2
  • 8
    • 84855471990 scopus 로고    scopus 로고
    • HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications
    • Khan O., La Thangue N.B. HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications. Immunol. Cell Biol. 2012, 90:85-94.
    • (2012) Immunol. Cell Biol. , vol.90 , pp. 85-94
    • Khan, O.1    La Thangue, N.B.2
  • 9
    • 10944270187 scopus 로고    scopus 로고
    • The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells
    • Revollo J.R., Grimm A.A., Imai S. The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells. J. Biol. Chem. 2004, 279:50754-50763.
    • (2004) J. Biol. Chem. , vol.279 , pp. 50754-50763
    • Revollo, J.R.1    Grimm, A.A.2    Imai, S.3
  • 12
    • 0035913911 scopus 로고    scopus 로고
    • Negative control of p53 by Sir2alpha promotes cell survival under stress
    • Luo J., Nikolaev A.Y., Imai S., Chen D., Su F., Shiloh A., Guarente L., Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 2001, 107:137-148.
    • (2001) Cell , vol.107 , pp. 137-148
    • Luo, J.1    Nikolaev, A.Y.2    Imai, S.3    Chen, D.4    Su, F.5    Shiloh, A.6    Guarente, L.7    Gu, W.8
  • 16
    • 0035099918 scopus 로고    scopus 로고
    • Role of T antigen interactions with p53 in tumorigenesis
    • Pipas J.M., Levine A.J. Role of T antigen interactions with p53 in tumorigenesis. Semin. Cancer Biol. 2001, 11:23-30.
    • (2001) Semin. Cancer Biol. , vol.11 , pp. 23-30
    • Pipas, J.M.1    Levine, A.J.2
  • 17
    • 0027508092 scopus 로고
    • The tumor suppressor p53 and the oncoprotein simian virus 40 T antigen bind to overlapping domains on the MDM2 protein
    • Brown D.R., Deb S., Munoz R.M., Subler M.A., Deb S.P. The tumor suppressor p53 and the oncoprotein simian virus 40 T antigen bind to overlapping domains on the MDM2 protein. Mol. Cell. Biol. 1993, 13:6849-6857.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 6849-6857
    • Brown, D.R.1    Deb, S.2    Munoz, R.M.3    Subler, M.A.4    Deb, S.P.5
  • 18
    • 43049163953 scopus 로고    scopus 로고
    • Acetylation is indispensable for p53 activation
    • Tang Y., Zhao W., Chen Y., Zhao Y., Gu W. Acetylation is indispensable for p53 activation. Cell 2008, 133:612-626.
    • (2008) Cell , vol.133 , pp. 612-626
    • Tang, Y.1    Zhao, W.2    Chen, Y.3    Zhao, Y.4    Gu, W.5
  • 20
    • 0037160097 scopus 로고    scopus 로고
    • Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1
    • Bitterman K.J., Anderson R.M., Cohen H.Y., Latorre-Esteves M., Sinclair D.A. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J. Biol. Chem. 2002, 277:45099-45107.
    • (2002) J. Biol. Chem. , vol.277 , pp. 45099-45107
    • Bitterman, K.J.1    Anderson, R.M.2    Cohen, H.Y.3    Latorre-Esteves, M.4    Sinclair, D.A.5
  • 21
    • 50949120914 scopus 로고    scopus 로고
    • Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition
    • Bogan K.L., Brenner C. Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition. Annu. Rev. Nutr. 2008, 28:115-130.
    • (2008) Annu. Rev. Nutr. , vol.28 , pp. 115-130
    • Bogan, K.L.1    Brenner, C.2
  • 22
    • 0242526050 scopus 로고    scopus 로고
    • FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis
    • Hasmann M., Schemainda I. FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis. Cancer Res. 2003, 63:7436-7442.
    • (2003) Cancer Res. , vol.63 , pp. 7436-7442
    • Hasmann, M.1    Schemainda, I.2
  • 23
    • 77958523925 scopus 로고    scopus 로고
    • NAD(+) -dependent histone deacetylases (sirtuins) as novel therapeutic targets
    • Schemies J., Uciechowska U., Sippl W., Jung M. NAD(+) -dependent histone deacetylases (sirtuins) as novel therapeutic targets. Med. Res. Rev. 2010, 30:861-889.
    • (2010) Med. Res. Rev. , vol.30 , pp. 861-889
    • Schemies, J.1    Uciechowska, U.2    Sippl, W.3    Jung, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.