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Volumn 28, Issue 2, 2014, Pages 106-116

New insights into manganese toxicity and speciation

Author keywords

Manganism; Mn exposure; Mn molecular interactions; Mn biomonitoring; Mn speciation

Indexed keywords

ACETYLCHOLINESTERASE; MANGANESE; MANGANESE SUPEROXIDE DISMUTASE; NEUROTRANSMITTER; REACTIVE OXYGEN METABOLITE; CATALASE; GLUTAMATE AMMONIA LIGASE; GLUTATHIONE PEROXIDASE; MEMBRANE PROTEIN; METAL TRANSPORTER PROTEIN; MONOCARBOXYLATE TRANSPORTER; ORGANIC ANION TRANSPORTER; SUPEROXIDE DISMUTASE; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 84898044856     PISSN: 0946672X     EISSN: 18783252     Source Type: Journal    
DOI: 10.1016/j.jtemb.2013.08.005     Document Type: Review
Times cited : (123)

References (105)
  • 1
    • 0043169339 scopus 로고    scopus 로고
    • Oxidative stress is induced in the rat brain following repeated inhalation exposure to manganese sulfate
    • Dobson A.W., Weber S., Dorman D.C., Lash L.K., Erikson K.M., Aschner M. Oxidative stress is induced in the rat brain following repeated inhalation exposure to manganese sulfate. Biol Trace Elem Res 2003, 93(1-3):113-126.
    • (2003) Biol Trace Elem Res , vol.93 , Issue.1-3 , pp. 113-126
    • Dobson, A.W.1    Weber, S.2    Dorman, D.C.3    Lash, L.K.4    Erikson, K.M.5    Aschner, M.6
  • 2
    • 67650571843 scopus 로고    scopus 로고
    • Neurological risks associated with manganese exposure from welding operations - a literature review
    • Flynn M.R., Susi P. Neurological risks associated with manganese exposure from welding operations - a literature review. Int J Hyg Environ Health 2009, 212(5):459-469.
    • (2009) Int J Hyg Environ Health , vol.212 , Issue.5 , pp. 459-469
    • Flynn, M.R.1    Susi, P.2
  • 3
    • 72949107609 scopus 로고    scopus 로고
    • Manganese flux across the blood-brain barrier
    • Yokel R.A. Manganese flux across the blood-brain barrier. Neuromol Med 2009, 11(4):297-310.
    • (2009) Neuromol Med , vol.11 , Issue.4 , pp. 297-310
    • Yokel, R.A.1
  • 4
    • 72949108889 scopus 로고    scopus 로고
    • From manganism to manganese-induced parkinsonism: a conceptual model based on the evolution of exposure
    • Lucchini R.G., Martin C.J., Doney B.C. From manganism to manganese-induced parkinsonism: a conceptual model based on the evolution of exposure. Neuromol Med 2009, 11(4):311-321.
    • (2009) Neuromol Med , vol.11 , Issue.4 , pp. 311-321
    • Lucchini, R.G.1    Martin, C.J.2    Doney, B.C.3
  • 5
    • 24044506991 scopus 로고    scopus 로고
    • Nutritional aspects of manganese homeostasis
    • Aschner J.L., Aschner M. Nutritional aspects of manganese homeostasis. Mol Aspects Med 2005, 26(4-5):353-362.
    • (2005) Mol Aspects Med , vol.26 , Issue.4-5 , pp. 353-362
    • Aschner, J.L.1    Aschner, M.2
  • 6
    • 72949123199 scopus 로고    scopus 로고
    • Manganese and its role in Parkinson's disease: from transport to neuropathology
    • Aschner M., Erikson K.M., Hernandez E.H., Tjalkens R. Manganese and its role in Parkinson's disease: from transport to neuropathology. Neuromol Med 2009, 11(4):252-266.
    • (2009) Neuromol Med , vol.11 , Issue.4 , pp. 252-266
    • Aschner, M.1    Erikson, K.M.2    Hernandez, E.H.3    Tjalkens, R.4
  • 7
    • 34248999831 scopus 로고    scopus 로고
    • Manganese: recent advances in understanding its transport and neurotoxicity
    • Aschner M., Guilarte T.R., Schneider J.S., Zheng W. Manganese: recent advances in understanding its transport and neurotoxicity. Toxicol Appl Pharmacol 2007, 221(2):131-147.
    • (2007) Toxicol Appl Pharmacol , vol.221 , Issue.2 , pp. 131-147
    • Aschner, M.1    Guilarte, T.R.2    Schneider, J.S.3    Zheng, W.4
  • 8
    • 2642541755 scopus 로고    scopus 로고
    • Manganese toxicokinetics at the blood-brain barrier
    • [discussion 59-73]
    • Yokel R.A., Crossgrove J.S. Manganese toxicokinetics at the blood-brain barrier. Res Rep Health Eff Inst 2004, 119(7-58). [discussion 59-73].
    • (2004) Res Rep Health Eff Inst , vol.119 , pp. 7-58
    • Yokel, R.A.1    Crossgrove, J.S.2
  • 9
    • 34347399955 scopus 로고    scopus 로고
    • Speciation and toxicological relevance of manganese in humans
    • Michalke B., Halbach S., Nischwitz V. Speciation and toxicological relevance of manganese in humans. J Environ Monit 2007, 9(7):650.
    • (2007) J Environ Monit , vol.9 , Issue.7 , pp. 650
    • Michalke, B.1    Halbach, S.2    Nischwitz, V.3
  • 10
    • 12344250905 scopus 로고    scopus 로고
    • Manganese toxicity upon overexposure
    • Crossgrove J., Zheng W. Manganese toxicity upon overexposure. NMR Biomed 2004, 17(8):544-553.
    • (2004) NMR Biomed , vol.17 , Issue.8 , pp. 544-553
    • Crossgrove, J.1    Zheng, W.2
  • 11
    • 0033616579 scopus 로고    scopus 로고
    • Manganese oxide minerals: crystal structures and economic and environmental significance
    • Post J.E. Manganese oxide minerals: crystal structures and economic and environmental significance. Proc Natl Acad Sci USA 1999, 96(7):3447-3454.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.7 , pp. 3447-3454
    • Post, J.E.1
  • 12
    • 84898033896 scopus 로고    scopus 로고
    • EPA. Manganese (CASRN 7439-96-5) [26.08.13]. Integrated Risk Information System.
    • EPA. Manganese (CASRN 7439-96-5) [26.08.13]. Integrated Risk Information System. http://www.epa.gov/iris/subst/0373.htm.
  • 13
    • 84898029276 scopus 로고
    • Environmental Protection Agency C, OH, US. Health assessment document for manganese: final report
    • Environmental Protection Agency C, OH, US. Health assessment document for manganese: final report. 1984.
    • (1984)
  • 17
    • 33846013944 scopus 로고    scopus 로고
    • Hair manganese and hyperactive behaviors: pilot study of school-age children exposed through tap water
    • Bouchard M., Laforest F., Vandelac L., Bellinger D., Mergler D. Hair manganese and hyperactive behaviors: pilot study of school-age children exposed through tap water. Environ Health Perspect 2007, 115(1):122-127.
    • (2007) Environ Health Perspect , vol.115 , Issue.1 , pp. 122-127
    • Bouchard, M.1    Laforest, F.2    Vandelac, L.3    Bellinger, D.4    Mergler, D.5
  • 18
    • 0038077372 scopus 로고    scopus 로고
    • Survey of arsenic and other heavy metals in food composites and drinking water and estimation of dietary intake by the villagers from an arsenic-affected area of West Bengal, India
    • Roychowdhury T., Tokunaga H., Ando M. Survey of arsenic and other heavy metals in food composites and drinking water and estimation of dietary intake by the villagers from an arsenic-affected area of West Bengal, India. Sci Total Environ 2003, 308(1-3):15-35.
    • (2003) Sci Total Environ , vol.308 , Issue.1-3 , pp. 15-35
    • Roychowdhury, T.1    Tokunaga, H.2    Ando, M.3
  • 19
    • 0036852332 scopus 로고    scopus 로고
    • The concentrations of arsenic and other toxic elements in Bangladesh's drinking water
    • Frisbie S.H., Ortega R., Maynard D.M., Sarkar B. The concentrations of arsenic and other toxic elements in Bangladesh's drinking water. Environ Health Perspect 2002, 110(11):1147-1153.
    • (2002) Environ Health Perspect , vol.110 , Issue.11 , pp. 1147-1153
    • Frisbie, S.H.1    Ortega, R.2    Maynard, D.M.3    Sarkar, B.4
  • 21
    • 0035068627 scopus 로고    scopus 로고
    • Influence of dietary manganese on the pharmacokinetics of inhaled manganese sulfate in male CD rats
    • Dorman D.C., Struve M.F., James R.A., McManus B.E., Marshall M.W., Wong B.A. Influence of dietary manganese on the pharmacokinetics of inhaled manganese sulfate in male CD rats. Toxicol Sci 2001, 60(2):242-251.
    • (2001) Toxicol Sci , vol.60 , Issue.2 , pp. 242-251
    • Dorman, D.C.1    Struve, M.F.2    James, R.A.3    McManus, B.E.4    Marshall, M.W.5    Wong, B.A.6
  • 22
    • 0036628678 scopus 로고    scopus 로고
    • Brain manganese concentrations in rats following manganese tetroxide inhalation are unaffected by dietary manganese intake
    • Dorman D.C., Struve M.F., Wong B.A. Brain manganese concentrations in rats following manganese tetroxide inhalation are unaffected by dietary manganese intake. Neurotoxicology 2002, 23(2):185-195.
    • (2002) Neurotoxicology , vol.23 , Issue.2 , pp. 185-195
    • Dorman, D.C.1    Struve, M.F.2    Wong, B.A.3
  • 23
    • 84862556431 scopus 로고    scopus 로고
    • Olfactory functions at the intersection between environmental exposure to manganese and Parkinsonism
    • Zoni S., Bonetti G., Lucchini R. Olfactory functions at the intersection between environmental exposure to manganese and Parkinsonism. J Trace Elem Med Biol 2012, 26(2-3):179-182.
    • (2012) J Trace Elem Med Biol , vol.26 , Issue.2-3 , pp. 179-182
    • Zoni, S.1    Bonetti, G.2    Lucchini, R.3
  • 24
    • 0024408679 scopus 로고
    • Manganese induced parkinsonism: an outbreak due to an unrepaired ventilation control system in a ferromanganese smelter
    • Wang J.D., Huang C.C., Hwang Y.H., Chiang J.R., Lin J.M., Chen J.S. Manganese induced parkinsonism: an outbreak due to an unrepaired ventilation control system in a ferromanganese smelter. Br J Ind Med 1989, 46(12):856-859.
    • (1989) Br J Ind Med , vol.46 , Issue.12 , pp. 856-859
    • Wang, J.D.1    Huang, C.C.2    Hwang, Y.H.3    Chiang, J.R.4    Lin, J.M.5    Chen, J.S.6
  • 25
    • 33846449858 scopus 로고    scopus 로고
    • Progressive motor syndrome in a welder with pallidal T1 hyperintensity on MRI: a two-year follow-up
    • Kenangil G., Ertan S., Sayilir I., Ozekmekci S. Progressive motor syndrome in a welder with pallidal T1 hyperintensity on MRI: a two-year follow-up. Mov Disord 2006, 21(12):2197-2200.
    • (2006) Mov Disord , vol.21 , Issue.12 , pp. 2197-2200
    • Kenangil, G.1    Ertan, S.2    Sayilir, I.3    Ozekmekci, S.4
  • 26
    • 84898032704 scopus 로고    scopus 로고
    • ACGIH®. TLVs® and BEIs®. ISBN: 978-1-882417-95-7
    • ACGIH®. TLVs® and BEIs®. ISBN: 978-1-882417-95-7; 2009.
    • (2009)
  • 27
    • 39849085811 scopus 로고    scopus 로고
    • Pharmacokinetic modeling of manganese in the rat IV: assessing factors that contribute to brain accumulation during inhalation exposure
    • Nong A., Teeguarden J.G., Clewell H.J., Dorman D.C., Andersen M.E. Pharmacokinetic modeling of manganese in the rat IV: assessing factors that contribute to brain accumulation during inhalation exposure. J Toxicol Environ Health Part A 2008, 71(7):413-426.
    • (2008) J Toxicol Environ Health Part A , vol.71 , Issue.7 , pp. 413-426
    • Nong, A.1    Teeguarden, J.G.2    Clewell, H.J.3    Dorman, D.C.4    Andersen, M.E.5
  • 28
    • 0031015237 scopus 로고    scopus 로고
    • Manganese in the U.S. gasoline supply
    • Frumkin H., Solomon G. Manganese in the U.S. gasoline supply. Am J Ind Med 1997, 31(1):107-115.
    • (1997) Am J Ind Med , vol.31 , Issue.1 , pp. 107-115
    • Frumkin, H.1    Solomon, G.2
  • 30
    • 0033038055 scopus 로고    scopus 로고
    • Effects from environmental Mn exposures: a review of the evidence from non-occupational exposure studies
    • Hudnell H.K. Effects from environmental Mn exposures: a review of the evidence from non-occupational exposure studies. Neurotoxicology 1999, 20(2-3):379-397.
    • (1999) Neurotoxicology , vol.20 , Issue.2-3 , pp. 379-397
    • Hudnell, H.K.1
  • 31
    • 0037656051 scopus 로고    scopus 로고
    • Manganese: a high-octane dispute
    • Kaiser J. Manganese: a high-octane dispute. Science 2003, 300(5621):926-928.
    • (2003) Science , vol.300 , Issue.5621 , pp. 926-928
    • Kaiser, J.1
  • 33
    • 0023882918 scopus 로고
    • Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication
    • Ferraz H.B., Bertolucci P.H., Pereira J.S., Lima J.G., Andrade L.A. Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication. Neurology 1988, 38(4):550-553.
    • (1988) Neurology , vol.38 , Issue.4 , pp. 550-553
    • Ferraz, H.B.1    Bertolucci, P.H.2    Pereira, J.S.3    Lima, J.G.4    Andrade, L.A.5
  • 34
    • 71049161520 scopus 로고    scopus 로고
    • Lifetime cumulative exposure as a threat for neurodegeneration: need for prevention strategies on a global scale
    • Lucchini R., Zimmerman N. Lifetime cumulative exposure as a threat for neurodegeneration: need for prevention strategies on a global scale. Neurotoxicology 2009, 30(6):1144-1148.
    • (2009) Neurotoxicology , vol.30 , Issue.6 , pp. 1144-1148
    • Lucchini, R.1    Zimmerman, N.2
  • 35
    • 0021173760 scopus 로고
    • Manganese intake and serum manganese concentration of human milk-fed and formula-fed infants
    • Stastny D., Vogel R.S., Picciano M.F. Manganese intake and serum manganese concentration of human milk-fed and formula-fed infants. Am J Clin Nutr 1984, 39(6):872-878.
    • (1984) Am J Clin Nutr , vol.39 , Issue.6 , pp. 872-878
    • Stastny, D.1    Vogel, R.S.2    Picciano, M.F.3
  • 36
    • 0142226864 scopus 로고    scopus 로고
    • The role of metals in neurodegenerative processes: aluminum, manganese, and zinc
    • Zatta P., Lucchini R., van Rensburg S.J., Taylor A. The role of metals in neurodegenerative processes: aluminum, manganese, and zinc. Brain Res Bull 2003, 62(1):15-28.
    • (2003) Brain Res Bull , vol.62 , Issue.1 , pp. 15-28
    • Zatta, P.1    Lucchini, R.2    van Rensburg, S.J.3    Taylor, A.4
  • 39
    • 70049116159 scopus 로고    scopus 로고
    • Analysis of settled dust with X-ray fluorescence for exposure assessment of metals in the province of Brescia, Italy
    • Zacco A., Resola S., Lucchini R., Albini E., Zimmerman N., Guazzetti S., Bontempi E. Analysis of settled dust with X-ray fluorescence for exposure assessment of metals in the province of Brescia, Italy. J Environ Monit 2009, 11(9):1579-1585.
    • (2009) J Environ Monit , vol.11 , Issue.9 , pp. 1579-1585
    • Zacco, A.1    Resola, S.2    Lucchini, R.3    Albini, E.4    Zimmerman, N.5    Guazzetti, S.6    Bontempi, E.7
  • 41
    • 34249795741 scopus 로고    scopus 로고
    • A study of the relationships between Parkinson's disease and markers of traffic-derived and environmental manganese air pollution in two Canadian cities
    • Finkelstein M.M., Jerrett M. A study of the relationships between Parkinson's disease and markers of traffic-derived and environmental manganese air pollution in two Canadian cities. Environ Res 2007, 104(3):420-432.
    • (2007) Environ Res , vol.104 , Issue.3 , pp. 420-432
    • Finkelstein, M.M.1    Jerrett, M.2
  • 43
    • 84866014309 scopus 로고    scopus 로고
    • Inverse association of intellectual function with very low blood lead but not with manganese exposure in Italian adolescents
    • Lucchini R.G., Zoni S., Guazzetti S., Bontempi E., Micheletti S., Broberg K., Parrinello G., Smith D.R. Inverse association of intellectual function with very low blood lead but not with manganese exposure in Italian adolescents. Environ Res 2012, 118:65-71.
    • (2012) Environ Res , vol.118 , pp. 65-71
    • Lucchini, R.G.1    Zoni, S.2    Guazzetti, S.3    Bontempi, E.4    Micheletti, S.5    Broberg, K.6    Parrinello, G.7    Smith, D.R.8
  • 48
    • 34247362462 scopus 로고    scopus 로고
    • The gestational environment and Parkinson's disease: evidence for neurodevelopmental origins of a neurodegenerative disorder
    • Barlow B.K., Cory-Slechta D.A., Richfield E.K., Thiruchelvam M. The gestational environment and Parkinson's disease: evidence for neurodevelopmental origins of a neurodegenerative disorder. Reprod Toxicol 2007, 23(3):457-470.
    • (2007) Reprod Toxicol , vol.23 , Issue.3 , pp. 457-470
    • Barlow, B.K.1    Cory-Slechta, D.A.2    Richfield, E.K.3    Thiruchelvam, M.4
  • 50
    • 34249803566 scopus 로고    scopus 로고
    • Neuropsychiatric symptoms and past manganese exposure in a ferro-alloy plant
    • Bouchard M., Mergler D., Baldwin M., Panisset M., Roels H.A. Neuropsychiatric symptoms and past manganese exposure in a ferro-alloy plant. Neurotoxicology 2007, 28(2):290-297.
    • (2007) Neurotoxicology , vol.28 , Issue.2 , pp. 290-297
    • Bouchard, M.1    Mergler, D.2    Baldwin, M.3    Panisset, M.4    Roels, H.A.5
  • 52
    • 14744283646 scopus 로고
    • Sur les effets du peroxide de manganèse
    • Couper J. Sur les effets du peroxide de manganèse. J Chim Méd Pharm Toxicol 1837, 3:223-225.
    • (1837) J Chim Méd Pharm Toxicol , vol.3 , pp. 223-225
    • Couper, J.1
  • 53
    • 33646184382 scopus 로고    scopus 로고
    • Economic implications of manganese neurotoxicity
    • Weiss B. Economic implications of manganese neurotoxicity. Neurotoxicology 2006, 27(3):362-368.
    • (2006) Neurotoxicology , vol.27 , Issue.3 , pp. 362-368
    • Weiss, B.1
  • 55
    • 84861212056 scopus 로고    scopus 로고
    • Impact of manganese on and transfer across blood-brain and blood-cerebrospinal fluid barrier in vitro
    • Bornhorst J., Wehe C.A., Huwel S., Karst U., Galla H-J., Schwerdtle T. Impact of manganese on and transfer across blood-brain and blood-cerebrospinal fluid barrier in vitro. J Biol Chem 2012, 287(21):17140-17151.
    • (2012) J Biol Chem , vol.287 , Issue.21 , pp. 17140-17151
    • Bornhorst, J.1    Wehe, C.A.2    Huwel, S.3    Karst, U.4    Galla, H.-J.5    Schwerdtle, T.6
  • 57
    • 52049086213 scopus 로고    scopus 로고
    • Speciation analysis of selected metals and determination of their total contents in paired serum and cerebrospinal fluid samples: an approach to investigate the permeability of the human blood-cerebrospinal fluid-barrier
    • Nischwitz V., Berthele A., Michalke B. Speciation analysis of selected metals and determination of their total contents in paired serum and cerebrospinal fluid samples: an approach to investigate the permeability of the human blood-cerebrospinal fluid-barrier. Anal Chim Acta 2008, 627(2):258-269.
    • (2008) Anal Chim Acta , vol.627 , Issue.2 , pp. 258-269
    • Nischwitz, V.1    Berthele, A.2    Michalke, B.3
  • 58
    • 46149116517 scopus 로고    scopus 로고
    • Manganese transport in eukaryotes: the role of DMT1
    • Au C., Benedetto A., Aschner M. Manganese transport in eukaryotes: the role of DMT1. Neurotoxicology 2008, 29(4):569-576.
    • (2008) Neurotoxicology , vol.29 , Issue.4 , pp. 569-576
    • Au, C.1    Benedetto, A.2    Aschner, M.3
  • 59
    • 33745907562 scopus 로고    scopus 로고
    • Upregulation of DMT1 expression in choroidal epithelia of the blood-CSF barrier following manganese exposure in vitro
    • Wang X., Li G.J., Zheng W. Upregulation of DMT1 expression in choroidal epithelia of the blood-CSF barrier following manganese exposure in vitro. Brain Res 2006, 1097(1):1-10.
    • (2006) Brain Res , vol.1097 , Issue.1 , pp. 1-10
    • Wang, X.1    Li, G.J.2    Zheng, W.3
  • 60
    • 1342347993 scopus 로고    scopus 로고
    • Manganese distribution across the blood-brain barrier III. The divalent metal transporter-1 is not the major mechanism mediating brain manganese uptake
    • Crossgrove J.S., Yokel R.A. Manganese distribution across the blood-brain barrier III. The divalent metal transporter-1 is not the major mechanism mediating brain manganese uptake. Neurotoxicology 2004, 25(3):451-460.
    • (2004) Neurotoxicology , vol.25 , Issue.3 , pp. 451-460
    • Crossgrove, J.S.1    Yokel, R.A.2
  • 61
    • 45049088251 scopus 로고    scopus 로고
    • Intracellular localization and subsequent redistribution of metal transporters in a rat choroid plexus model following exposure to manganese or iron
    • Wang X., Miller D.S., Zheng W. Intracellular localization and subsequent redistribution of metal transporters in a rat choroid plexus model following exposure to manganese or iron. Toxicol Appl Pharmacol 2008, 230(2):167-174.
    • (2008) Toxicol Appl Pharmacol , vol.230 , Issue.2 , pp. 167-174
    • Wang, X.1    Miller, D.S.2    Zheng, W.3
  • 63
    • 58049202877 scopus 로고    scopus 로고
    • Ceruloplasmin alters the tissue disposition and neurotoxicity of manganese, but not its loading onto transferrin
    • Jursa T., Smith D.R. Ceruloplasmin alters the tissue disposition and neurotoxicity of manganese, but not its loading onto transferrin. Toxicol Sci 2009, 107(1):182-193.
    • (2009) Toxicol Sci , vol.107 , Issue.1 , pp. 182-193
    • Jursa, T.1    Smith, D.R.2
  • 65
    • 79961208520 scopus 로고    scopus 로고
    • Manganese induces oxidative stress, redox state unbalance and disrupts membrane bound ATPases on murine neuroblastoma cells in vitro: protective role of silymarin
    • Chtourou Y., Trabelsi K., Fetoui H., Mkannez G., Kallel H., Zeghal N. Manganese induces oxidative stress, redox state unbalance and disrupts membrane bound ATPases on murine neuroblastoma cells in vitro: protective role of silymarin. Neurochem Res 2011, 36(8):1546-1557.
    • (2011) Neurochem Res , vol.36 , Issue.8 , pp. 1546-1557
    • Chtourou, Y.1    Trabelsi, K.2    Fetoui, H.3    Mkannez, G.4    Kallel, H.5    Zeghal, N.6
  • 66
    • 84856113283 scopus 로고    scopus 로고
    • The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the rat brain
    • Santos D., Milatovic D., Andrade V., Batoreu M.C., Aschner M., Marreilha dos Santos A.P. The inhibitory effect of manganese on acetylcholinesterase activity enhances oxidative stress and neuroinflammation in the rat brain. Toxicology 2012, 292(2-3):90-98.
    • (2012) Toxicology , vol.292 , Issue.2-3 , pp. 90-98
    • Santos, D.1    Milatovic, D.2    Andrade, V.3    Batoreu, M.C.4    Aschner, M.5    Marreilha dos Santos, A.P.6
  • 67
    • 80855148194 scopus 로고    scopus 로고
    • Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury
    • Milatovic D., Gupta R.C., Yu Y.C., Zaja-Milatovic S., Aschner M. Protective effects of antioxidants and anti-inflammatory agents against manganese-induced oxidative damage and neuronal injury. Toxicol Appl Pharmacol 2011, 256(3):219-226.
    • (2011) Toxicol Appl Pharmacol , vol.256 , Issue.3 , pp. 219-226
    • Milatovic, D.1    Gupta, R.C.2    Yu, Y.C.3    Zaja-Milatovic, S.4    Aschner, M.5
  • 68
    • 47649128756 scopus 로고    scopus 로고
    • Effects of short-term exposure to manganese on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na,K)-ATPase and Mg-ATPase: modulation by l-cysteine
    • Liapi C., Zarros A., Galanopoulou P., Theocharis S., Skandali N., Al-Humadi H., Anifantaki F., Gkrouzman E., Mellios Z., Tsakiris S. Effects of short-term exposure to manganese on the adult rat brain antioxidant status and the activities of acetylcholinesterase, (Na,K)-ATPase and Mg-ATPase: modulation by l-cysteine. Basic Clin Pharmacol Toxicol 2008, 103(2):171-175.
    • (2008) Basic Clin Pharmacol Toxicol , vol.103 , Issue.2 , pp. 171-175
    • Liapi, C.1    Zarros, A.2    Galanopoulou, P.3    Theocharis, S.4    Skandali, N.5    Al-Humadi, H.6    Anifantaki, F.7    Gkrouzman, E.8    Mellios, Z.9    Tsakiris, S.10
  • 69
    • 84855250540 scopus 로고    scopus 로고
    • Neurohepatic toxicity of subacute manganese chloride exposure and potential chemoprotective effects of lycopene
    • Lebda M.A., El-Neweshy M.S., El-Sayed Y.S. Neurohepatic toxicity of subacute manganese chloride exposure and potential chemoprotective effects of lycopene. Neurotoxicology 2012, 33(1):98-104.
    • (2012) Neurotoxicology , vol.33 , Issue.1 , pp. 98-104
    • Lebda, M.A.1    El-Neweshy, M.S.2    El-Sayed, Y.S.3
  • 70
    • 0021230284 scopus 로고
    • Differences in the neurotoxic effects of manganese during development and aging: some observations on brain regional neurotransmitter and non-neurotransmitter metabolism in a developmental rat model of chronic manganese encephalopathy
    • Lai J.C., Leung T.K., Lim L. Differences in the neurotoxic effects of manganese during development and aging: some observations on brain regional neurotransmitter and non-neurotransmitter metabolism in a developmental rat model of chronic manganese encephalopathy. Neurotoxicology 1984, 5(1):37-47.
    • (1984) Neurotoxicology , vol.5 , Issue.1 , pp. 37-47
    • Lai, J.C.1    Leung, T.K.2    Lim, L.3
  • 71
    • 0019773886 scopus 로고
    • Water intake and brain choline-acetyltransferase and acetylcholinesterase activities in manganese treated rats
    • Martinez H., Bonilla E. Water intake and brain choline-acetyltransferase and acetylcholinesterase activities in manganese treated rats. Neurobehav Toxicol Teratol 1981, 3(3):277-280.
    • (1981) Neurobehav Toxicol Teratol , vol.3 , Issue.3 , pp. 277-280
    • Martinez, H.1    Bonilla, E.2
  • 72
    • 33645867691 scopus 로고    scopus 로고
    • The effects of manganese on glutamate, dopamine and gamma-aminobutyric acid regulation
    • Fitsanakis V.A., Au C., Erikson K.M., Aschner M. The effects of manganese on glutamate, dopamine and gamma-aminobutyric acid regulation. Neurochem Int 2006, 48(6-7):426-433.
    • (2006) Neurochem Int , vol.48 , Issue.6-7 , pp. 426-433
    • Fitsanakis, V.A.1    Au, C.2    Erikson, K.M.3    Aschner, M.4
  • 73
    • 33845679067 scopus 로고    scopus 로고
    • Brain manganese accumulation is inversely related to gamma-amino butyric acid uptake in male and female rats
    • Anderson J.G., Cooney P.T., Erikson K.M. Brain manganese accumulation is inversely related to gamma-amino butyric acid uptake in male and female rats. Toxicol Sci 2007, 95(1):188-195.
    • (2007) Toxicol Sci , vol.95 , Issue.1 , pp. 188-195
    • Anderson, J.G.1    Cooney, P.T.2    Erikson, K.M.3
  • 74
    • 56249101317 scopus 로고    scopus 로고
    • Manganese exposure alters extracellular GABA, GABA receptor and transporter protein and mRNA levels in the developing rat brain
    • Anderson J.G., Fordahl S.C., Cooney P.T., Weaver T.L., Colyer C.L., Erikson K.M. Manganese exposure alters extracellular GABA, GABA receptor and transporter protein and mRNA levels in the developing rat brain. Neurotoxicology 2008, 29(6):1044-1053.
    • (2008) Neurotoxicology , vol.29 , Issue.6 , pp. 1044-1053
    • Anderson, J.G.1    Fordahl, S.C.2    Cooney, P.T.3    Weaver, T.L.4    Colyer, C.L.5    Erikson, K.M.6
  • 75
    • 34249706788 scopus 로고    scopus 로고
    • Low-level manganese exposure alters glutamate metabolism in GABAergic AF5 cells
    • Crooks D.R., Welch N., Smith D.R. Low-level manganese exposure alters glutamate metabolism in GABAergic AF5 cells. Neurotoxicology 2007, 28(3):548-554.
    • (2007) Neurotoxicology , vol.28 , Issue.3 , pp. 548-554
    • Crooks, D.R.1    Welch, N.2    Smith, D.R.3
  • 79
    • 58049213897 scopus 로고    scopus 로고
    • Manganese induces dopaminergic neurodegeneration via microglial activation in a rat model of manganism
    • Zhao F., Cai T., Liu M., Zheng G., Luo W., Chen J. Manganese induces dopaminergic neurodegeneration via microglial activation in a rat model of manganism. Toxicol Sci 2008, 107(1):156-164.
    • (2008) Toxicol Sci , vol.107 , Issue.1 , pp. 156-164
    • Zhao, F.1    Cai, T.2    Liu, M.3    Zheng, G.4    Luo, W.5    Chen, J.6
  • 80
    • 78149245357 scopus 로고    scopus 로고
    • Manganese inhibits poly(ADP-ribosyl)ation in human cells: a possible mechanism behind manganese-induced toxicity?
    • Bornhorst J., Ebert F., Hartwig A., Michalke B., Schwerdtle T. Manganese inhibits poly(ADP-ribosyl)ation in human cells: a possible mechanism behind manganese-induced toxicity?. J Environ Monit 2010, 12(11):2062.
    • (2010) J Environ Monit , vol.12 , Issue.11 , pp. 2062
    • Bornhorst, J.1    Ebert, F.2    Hartwig, A.3    Michalke, B.4    Schwerdtle, T.5
  • 84
    • 81855168340 scopus 로고    scopus 로고
    • Mechanisms of manganese-induced neurotoxicity in primary neuronal cultures: the role of manganese speciation and cell type
    • Hernandez R.B., Farina M., Esposito B.P., Souza-Pinto N.C., Barbosa F., Sunol C. Mechanisms of manganese-induced neurotoxicity in primary neuronal cultures: the role of manganese speciation and cell type. Toxicol Sci 2011, 124(2):414-423.
    • (2011) Toxicol Sci , vol.124 , Issue.2 , pp. 414-423
    • Hernandez, R.B.1    Farina, M.2    Esposito, B.P.3    Souza-Pinto, N.C.4    Barbosa, F.5    Sunol, C.6
  • 85
    • 72949094441 scopus 로고    scopus 로고
    • Are there common biochemical and molecular mechanisms controlling manganism and parkisonism
    • Roth J.A. Are there common biochemical and molecular mechanisms controlling manganism and parkisonism. Neuromol Med 2009, 11(4):281-296.
    • (2009) Neuromol Med , vol.11 , Issue.4 , pp. 281-296
    • Roth, J.A.1
  • 88
    • 84875497828 scopus 로고    scopus 로고
    • Golgi phosphoprotein 4 (GPP130) is a sensitive and selective cellular target of manganese exposure
    • Masuda M., Braun-Sommargren M., Crooks D., Smith D.R. Golgi phosphoprotein 4 (GPP130) is a sensitive and selective cellular target of manganese exposure. Synapse 2012, 67(5):205-215.
    • (2012) Synapse , vol.67 , Issue.5 , pp. 205-215
    • Masuda, M.1    Braun-Sommargren, M.2    Crooks, D.3    Smith, D.R.4
  • 89
    • 0023235313 scopus 로고
    • Manganism in a neurological ethnic complex in northern Australia
    • Cawte J., Hams G., Kilburn C. Manganism in a neurological ethnic complex in northern Australia. Lancet 1987, 329(8544):1257.
    • (1987) Lancet , vol.329 , Issue.8544 , pp. 1257
    • Cawte, J.1    Hams, G.2    Kilburn, C.3
  • 90
    • 0034583221 scopus 로고    scopus 로고
    • Guidelines for terms related to chemical speciation and fractionation of elements. Definitions, structural aspects, and methodological approaches (IUPAC Recommendations 2000)
    • Templeton D.M., Ariese F., Cornelis R., Danielsson L.G., Muntau H., Van Leeuwen H.P., Lobinski R. Guidelines for terms related to chemical speciation and fractionation of elements. Definitions, structural aspects, and methodological approaches (IUPAC Recommendations 2000). Pure Appl Chem 2000, 72(8):1453-1470.
    • (2000) Pure Appl Chem , vol.72 , Issue.8 , pp. 1453-1470
    • Templeton, D.M.1    Ariese, F.2    Cornelis, R.3    Danielsson, L.G.4    Muntau, H.5    Van Leeuwen, H.P.6    Lobinski, R.7
  • 91
    • 5644294518 scopus 로고    scopus 로고
    • Manganese speciation using capillary electrophoresis - ICP-mass spectrometry
    • Michalke B. Manganese speciation using capillary electrophoresis - ICP-mass spectrometry. J Chromatogr A 2004, 1050(1):69-76.
    • (2004) J Chromatogr A , vol.1050 , Issue.1 , pp. 69-76
    • Michalke, B.1
  • 92
    • 34248222780 scopus 로고    scopus 로고
    • Manganese speciation in human cerebrospinal fluid using CZE coupled to inductively coupled plasma MS
    • Michalke B., Berthele A., Mistriotis P., Ochsenkuhn-Petropoulou M., Halbach S. Manganese speciation in human cerebrospinal fluid using CZE coupled to inductively coupled plasma MS. Electrophoresis 2007, 28(9):1380-1386.
    • (2007) Electrophoresis , vol.28 , Issue.9 , pp. 1380-1386
    • Michalke, B.1    Berthele, A.2    Mistriotis, P.3    Ochsenkuhn-Petropoulou, M.4    Halbach, S.5
  • 93
    • 0037234204 scopus 로고    scopus 로고
    • Manganese distribution across the blood-brain barrier, I. Evidence for carrier-mediated influx of managanese citrate as well as manganese and manganese transferrin
    • Crossgrove J.S., Allen D.D., Bukaveckas B.L., Rhineheimer S.S., Yokel R.A. Manganese distribution across the blood-brain barrier, I. Evidence for carrier-mediated influx of managanese citrate as well as manganese and manganese transferrin. Neurotoxicology 2003, 24(1):3-13.
    • (2003) Neurotoxicology , vol.24 , Issue.1 , pp. 3-13
    • Crossgrove, J.S.1    Allen, D.D.2    Bukaveckas, B.L.3    Rhineheimer, S.S.4    Yokel, R.A.5
  • 94
    • 84867847547 scopus 로고    scopus 로고
    • Manganese and iron species in Sprague-Dawley rats exposed with MnCl2 center dot 4H(2)O (i.v.)
    • Diederich J., Brielmeier M., Schwerdtle T., Michalke B. Manganese and iron species in Sprague-Dawley rats exposed with MnCl2 center dot 4H(2)O (i.v.). Microchem J 2012, 105:115-123.
    • (2012) Microchem J , vol.105 , pp. 115-123
    • Diederich, J.1    Brielmeier, M.2    Schwerdtle, T.3    Michalke, B.4
  • 95
    • 84878285216 scopus 로고    scopus 로고
    • Manganese speciation in paired serum and CSF samples using SEC-DRC-ICP-MS and CE-ICP-DRC-MS
    • Michalke B., Lucio M., Berthele A., Kanawati B. Manganese speciation in paired serum and CSF samples using SEC-DRC-ICP-MS and CE-ICP-DRC-MS. Anal Bioanal Chem 2013, 405(7):2301-2309.
    • (2013) Anal Bioanal Chem , vol.405 , Issue.7 , pp. 2301-2309
    • Michalke, B.1    Lucio, M.2    Berthele, A.3    Kanawati, B.4
  • 96
    • 67650921510 scopus 로고    scopus 로고
    • Electrospray ionisation with selected reaction monitoring for the determination of Mn-citrate, Fe-citrate, Cu-citrate and Zn-citrate
    • Nischwitz V., Michalke B. Electrospray ionisation with selected reaction monitoring for the determination of Mn-citrate, Fe-citrate, Cu-citrate and Zn-citrate. Rapid Commun Mass Spectrom 2009, 23(15):2338-2346.
    • (2009) Rapid Commun Mass Spectrom , vol.23 , Issue.15 , pp. 2338-2346
    • Nischwitz, V.1    Michalke, B.2
  • 98
    • 84864303776 scopus 로고    scopus 로고
    • Manganese in plasma: a promising biomarker of exposure to Mn in welders. A pilot study
    • Hoet P., Vanmarcke E., Geens T., Deumer G., Haufroid V., Roels H.A. Manganese in plasma: a promising biomarker of exposure to Mn in welders. A pilot study. Toxicol Lett 2012, 213(1):69-74.
    • (2012) Toxicol Lett , vol.213 , Issue.1 , pp. 69-74
    • Hoet, P.1    Vanmarcke, E.2    Geens, T.3    Deumer, G.4    Haufroid, V.5    Roels, H.A.6
  • 99
    • 13844269120 scopus 로고    scopus 로고
    • Alteration of serum concentrations of manganese, iron, ferritin, and transferrin receptor following exposure to welding fumes among career welders
    • Lu L., Zhang L.L., Li G.J., Guo W., Liang W., Zheng W. Alteration of serum concentrations of manganese, iron, ferritin, and transferrin receptor following exposure to welding fumes among career welders. Neurotoxicology 2005, 26(2):257-265.
    • (2005) Neurotoxicology , vol.26 , Issue.2 , pp. 257-265
    • Lu, L.1    Zhang, L.L.2    Li, G.J.3    Guo, W.4    Liang, W.5    Zheng, W.6
  • 100
    • 32344441585 scopus 로고    scopus 로고
    • Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site
    • Wright R.O., Amarasiriwardena C., Woolf A.D., Jim R., Bellinger D.C. Neuropsychological correlates of hair arsenic, manganese, and cadmium levels in school-age children residing near a hazardous waste site. Neurotoxicology 2006, 27(2):210-216.
    • (2006) Neurotoxicology , vol.27 , Issue.2 , pp. 210-216
    • Wright, R.O.1    Amarasiriwardena, C.2    Woolf, A.D.3    Jim, R.4    Bellinger, D.C.5
  • 103
    • 66149086560 scopus 로고    scopus 로고
    • Manganese exposure among smelting workers: blood manganese-iron ratio as a novel tool for manganese exposure assessment
    • Cowan D.M., Fan Q.Y., Zou Y., Shi X.J., Chen J., Aschner M., Rosenthal F.S., Zheng W. Manganese exposure among smelting workers: blood manganese-iron ratio as a novel tool for manganese exposure assessment. Biomarkers 2009, 14(1):3-16.
    • (2009) Biomarkers , vol.14 , Issue.1 , pp. 3-16
    • Cowan, D.M.1    Fan, Q.Y.2    Zou, Y.3    Shi, X.J.4    Chen, J.5    Aschner, M.6    Rosenthal, F.S.7    Zheng, W.8
  • 104
    • 71049181470 scopus 로고    scopus 로고
    • Manganese exposure among smelting workers: relationship between blood manganese-iron ratio and early onset neurobehavioral alterations
    • Cowan D.M., Zheng W., Zou Y., Shi X.J., Chen J., Rosenthal F.S., Fan Q.Y. Manganese exposure among smelting workers: relationship between blood manganese-iron ratio and early onset neurobehavioral alterations. Neurotoxicology 2009, 30(6):1214-1222.
    • (2009) Neurotoxicology , vol.30 , Issue.6 , pp. 1214-1222
    • Cowan, D.M.1    Zheng, W.2    Zou, Y.3    Shi, X.J.4    Chen, J.5    Rosenthal, F.S.6    Fan, Q.Y.7
  • 105
    • 77953818699 scopus 로고    scopus 로고
    • Rapid size fractionation of metal species in paired human serum and cerebrospinal fluid samples using ultrafiltration with off-line element selective detection
    • Nischwitz V., Berthele A., Michalke B. Rapid size fractionation of metal species in paired human serum and cerebrospinal fluid samples using ultrafiltration with off-line element selective detection. J Anal At Spectrom 2010, 25(7):1130-1137.
    • (2010) J Anal At Spectrom , vol.25 , Issue.7 , pp. 1130-1137
    • Nischwitz, V.1    Berthele, A.2    Michalke, B.3


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