메뉴 건너뛰기




Volumn 199, Issue 7, 2009, Pages 1019-1028

Interleukin-7 receptor signaling is deficient in CD4 + T Cells from HIV-infected persons and is inversely associated with aging

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CD27 ANTIGEN; CD45RA ANTIGEN; CD45RO ANTIGEN; INTERLEUKIN 7 RECEPTOR; STAT5 PROTEIN; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

EID: 65549141213     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/597210     Document Type: Article
Times cited : (48)

References (50)
  • 1
    • 0028929565 scopus 로고
    • Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine
    • von Freeden-Jeffry U, Vieira P, Lucian LA, McNeil T, Burdach SE, Murray R. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J Exp Med 1995; 181:1519-26.
    • (1995) J Exp Med , vol.181 , pp. 1519-26
    • Vonfreeden-Jeffry, U.1    Vieira, P.2    Lucian, L.A.3    McNeil, T.4    Burdach, S.E.5    Murray, R.6
  • 2
    • 0031587875 scopus 로고    scopus 로고
    • Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1mice
    • Maraskovsky E, O'Reilly LA, Teepe M, Corcoran LM, Peschon JJ, Strasser A. Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1mice. Cell 1997; 89: 1011-9.
    • (1997) Cell , vol.89 , pp. 1011-9
    • Maraskovsky, E.1    O'Reilly, L.A.2    Teepe, M.3    Corcoran, L.M.4    Peschon, J.J.5    Strasser, A.6
  • 3
    • 0027988545 scopus 로고
    • Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice
    • Peschon JJ, Morrissey PJ, Grabstein KH, et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J Exp Med 1994; 180:1955-60.
    • (1994) J Exp Med , vol.180 , pp. 1955-60
    • Peschon, J.J.1    Morrissey, P.J.2    Grabstein, K.H.3
  • 4
    • 19944433384 scopus 로고    scopus 로고
    • Interleukin-7 receptor -(IL-7R-) deficiency: Cellular and molecular bases: Analysis of clinical, immunological, and molecular features in 16 novel patients
    • Giliani S, Mori L, de Saint Basile G, et al. Interleukin-7 receptor- (IL-7R-) deficiency: cellular and molecular bases: analysis of clinical, immunological, and molecular features in 16 novel patients. Immunol Rev 2005; 203:110-26.
    • (2005) Immunol Rev , vol.203 , pp. 110-26
    • Giliani, S.1    Mori, L.2    Desaintbasile, G.3
  • 5
    • 0038784460 scopus 로고    scopus 로고
    • Effects of IL-7 on early human thymocyte progenitor cells in vitro and in SCID-hu Thy/Liv mice
    • Napolitano LA, Stoddart CA, Hanley MB, Wieder E, McCune JM. Effects of IL-7 on early human thymocyte progenitor cells in vitro and in SCID-hu Thy/Liv mice. J Immunol 2003; 171:645-54.
    • (2003) J Immunol , vol.171 , pp. 645-54
    • Napolitano, L.A.1    Stoddart, C.A.2    Hanley, M.B.3    Wieder, E.4    McCune, J.M.5
  • 6
    • 0037089233 scopus 로고    scopus 로고
    • Effects of exogenous interleukin-7 on human thymus function
    • Okamoto Y, Douek DC, McFarland RD, Koup RA. Effects of exogenous interleukin-7 on human thymus function. Blood 2002; 99:2851-8.
    • (2002) Blood , vol.99 , pp. 2851-8
    • Okamoto, Y.1    Douek, D.C.2    McFarland, R.D.3    Koup, R.A.4
  • 7
    • 0034332403 scopus 로고    scopus 로고
    • Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo
    • Schluns KS, Kieper WC, Jameson SC, Lefrancois L. Interleukin-7 mediates the homeostasis of naive and memory CD8 T cells in vivo. Nat Immunol 2000; 1:426-32.
    • (2000) Nat Immunol , vol.1 , pp. 426-32
    • Schluns, K.S.1    Kieper, W.C.2    Jameson, S.C.3    Lefrancois, L.4
  • 8
    • 0038487052 scopus 로고    scopus 로고
    • Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells
    • Seddon B, Tomlinson P, Zamoyska R. Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells. Nat Immunol 2003; 4:680-6.
    • (2003) Nat Immunol , vol.4 , pp. 680-6
    • Seddon, B.1    Tomlinson, P.2    Zamoyska, R.3
  • 9
    • 0035902513 scopus 로고    scopus 로고
    • IL-7 is critical for homeostatic proliferation and survival of naive T cells
    • Tan JT, Dudl E, LeRoy E, et al. IL-7 is critical for homeostatic proliferation and survival of naive T cells. Proc Natl Acad Sci U S A 2001; 98: 8732-7.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 8732-7
    • Tan, J.T.1    Dudl, E.2    Leroy, E.3
  • 10
    • 40449083885 scopus 로고    scopus 로고
    • Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7R- on central and effector memory CD4- and CD8- T cell subsets
    • Mercier F, Boulassel MR, Yassine-Diab B, et al. Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7R- on central and effector memory CD4- and CD8- T cell subsets. Clin Exp Immunol 2008; 152:72-80.
    • (2008) Clin Exp Immunol , vol.152 , pp. 72-80
    • Mercier, F.1    Boulassel, M.R.2    Yassine-Diab, B.3
  • 11
    • 0035138982 scopus 로고    scopus 로고
    • Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: Implications for T-cell homeostasis
    • Napolitano LA, Grant RM, Deeks SG, et al. Increased production of IL-7 accompanies HIV-1-mediated T-cell depletion: implications for T-cell homeostasis. Nat Med 2001; 7:73-9.
    • (2001) Nat Med , vol.7 , pp. 73-9
    • Napolitano, L.A.1    Grant, R.M.2    Deeks, S.G.3
  • 12
    • 36048944848 scopus 로고    scopus 로고
    • Interleukin-7 enhances proliferation responses to T-cell receptor stimulation in naive CD4- T cells from human immunodeficiency virus-infected persons
    • Bazdar DA, Sieg SF. Interleukin-7 enhances proliferation responses to T-cell receptor stimulation in naive CD4- T cells from human immunodeficiency virus-infected persons. J Virol 2007; 81:12670-4.
    • (2007) J Virol , vol.81 , pp. 12670-4
    • Bazdar, D.A.1    Sieg, S.F.2
  • 13
    • 0028874974 scopus 로고
    • Interleukin-7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells
    • Foxwell BM, Beadling C, Guschin D, Kerr I, Cantrell D. Interleukin-7 can induce the activation of Jak 1, Jak 3 and STAT 5 proteins in murine T cells. Eur J Immunol 1995; 25:3041-6.
    • (1995) Eur J Immunol , vol.25 , pp. 3041-6
    • Foxwell, B.M.1    Beadling, C.2    Guschin, D.3    Kerr, I.4    Cantrell, D.5
  • 14
    • 10744228466 scopus 로고    scopus 로고
    • Distinct effects of STAT5 activation on CD4- and CD8- T cell homeostasis: Development of CD4-CD25- regulatory T cells versus CD8- memory T cells
    • Burchill MA, Goetz CA, Prlic M, et al. Distinct effects of STAT5 activation on CD4- and CD8- T cell homeostasis: development of CD4-CD25- regulatory T cells versus CD8- memory T cells. J Immunol 2003; 171:5853-64.
    • (2003) J Immunol , vol.171 , pp. 5853-64
    • Burchill, M.A.1    Goetz, C.A.2    Prlic, M.3
  • 15
    • 33746893816 scopus 로고    scopus 로고
    • Constitutive activation of STAT5 supersedes the requirement for cytokine and TCR engage-ment of CD4- T cells in steady-state homeostasis
    • Taylor DK, Walsh PT, LaRosa DF, et al. Constitutive activation of STAT5 supersedes the requirement for cytokine and TCR engage-ment of CD4- T cells in steady-state homeostasis. J Immunol 2006; 177: 2216-23.
    • (2006) J Immunol , vol.177 , pp. 2216-23
    • Taylor, D.K.1    Walsh, P.T.2    LaRosa, D.F.3
  • 16
    • 33845923061 scopus 로고    scopus 로고
    • IL-7/STAT5 cytokine signaling pathway is essential but insufficient for maintenance of naive CD4 T cell survival in peripheral lymphoid organs
    • Seki Y, Yang J, Okamoto M, et al. IL-7/STAT5 cytokine signaling pathway is essential but insufficient for maintenance of naive CD4 T cell survival in peripheral lymphoid organs. J Immunol 2007; 178:262-70.
    • (2007) J Immunol , vol.178 , pp. 262-70
    • Seki, Y.1    Yang, J.2    Okamoto, M.3
  • 17
    • 32244444750 scopus 로고    scopus 로고
    • Stat5a/b are essential for normal lymphoid development and differentiation
    • U S A
    • Yao Z, Cui Y, Watford WT, et al. Stat5a/b are essential for normal lymphoid development and differentiation. Proc Natl Acad Sci U S A 2006; 103:1000-5.
    • (2006) Proc Natl Acad Sci , vol.103 , pp. 1000-5
    • Yao, Z.1    Cui, Y.2    Watford, W.T.3
  • 19
    • 33845875194 scopus 로고    scopus 로고
    • Acquisition of direct antiviral effector functions by CMV-specific CD4- T lymphocytes with cellular maturation
    • Casazza JP, Betts MR, Price DA, et al. Acquisition of direct antiviral effector functions by CMV-specific CD4- T lymphocytes with cellular maturation. J Exp Med 2006; 203:2865-77.
    • (2006) J Exp Med , vol.203 , pp. 2865-77
    • Casazza, J.P.1    Betts, M.R.2    Price, D.A.3
  • 20
    • 0842343430 scopus 로고    scopus 로고
    • HIV-1-specific memory CD4- T cells are phenotypically less mature than cytomegalovirus-specific memory CD4- T cells
    • Yue FY, Kovacs CM, Dimayuga RC, Parks P, Ostrowski MA. HIV-1-specific memory CD4- T cells are phenotypically less mature than cytomegalovirus-specific memory CD4- T cells. J Immunol 2004; 172: 2476-86.
    • (2004) J Immunol , vol.172 , pp. 2476-86
    • Yue, F.Y.1    Kovacs, C.M.2    Dimayuga, R.C.3    Parks, P.4    Ostrowski, M.A.5
  • 21
    • 29144470075 scopus 로고    scopus 로고
    • Functional and phenotypic characterization of CD57-CD4- T cells and their association with HIV-1-induced T cell dysfunction
    • Palmer BE, Blyveis N, Fontenot AP, Wilson CC. Functional and phenotypic characterization of CD57-CD4- T cells and their association with HIV-1-induced T cell dysfunction. J Immunol 2005; 175:8415-23.
    • (2005) J Immunol , vol.175 , pp. 8415-23
    • Palmer, B.E.1    Blyveis, N.2    Fontenot, A.P.3    Wilson, C.C.4
  • 22
    • 0026749407 scopus 로고
    • Phenotypic comparison of the three populations of human lymphocytes defined by CD45RO and CD45RA expression
    • Prince HE, York J, Jensen ER. Phenotypic comparison of the three populations of human lymphocytes defined by CD45RO and CD45RA expression. Cell Immunol 1992; 145:254-62.
    • (1992) Cell Immunol , vol.145 , pp. 254-62
    • Prince, H.E.1    York, J.2    Jensen, E.R.3
  • 23
    • 27944503411 scopus 로고    scopus 로고
    • Loss of IL-7R- is associated with CD4 T-cell depletion, high interleukin-7 levels and CD28 down-regulation in HIV infected patients
    • Rethi B, Fluur C, Atlas A, et al. Loss of IL-7R- is associated with CD4 T-cell depletion, high interleukin-7 levels and CD28 down-regulation in HIV infected patients. AIDS 2005; 19:2077-86.
    • (2005) AIDS , vol.19 , pp. 2077-86
    • Rethi, B.1    Fluur, C.2    Atlas, A.3
  • 24
    • 32044457728 scopus 로고    scopus 로고
    • Increased plasma interleukin-7 level correlates with decreased CD127 and Increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection
    • Sasson SC, Zaunders JJ, Zanetti G, et al. Increased plasma interleukin-7 level correlates with decreased CD127 and Increased CD132 extracellular expression on T cell subsets in patients with HIV-1 infection. J Infect Dis 2006; 193:505-14.
    • (2006) J Infect Dis , vol.193 , pp. 505-14
    • Sasson, S.C.1    Zaunders, J.J.2    Zanetti, G.3
  • 25
    • 4143085811 scopus 로고    scopus 로고
    • Suppression of IL7R- transcription by IL-7 and other prosurvival cytokines: A novel mechanism for maximizing IL-7-dependent T cell survival
    • Park JH, Yu Q, Erman B, et al. Suppression of IL7R- transcription by IL-7 and other prosurvival cytokines: a novel mechanism for maximizing IL-7-dependent T cell survival. Immunity 2004; 21:289-302.
    • (2004) Immunity , vol.21 , pp. 289-302
    • Park, J.H.1    Yu, Q.2    Erman, B.3
  • 27
    • 10344246581 scopus 로고    scopus 로고
    • HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation
    • Dion ML, Poulin JF, Bordi R, et al. HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation. Immunity 2004; 21:757-68.
    • (2004) Immunity , vol.21 , pp. 757-68
    • Dion, M.L.1    Poulin, J.F.2    Bordi, R.3
  • 28
    • 17444372347 scopus 로고    scopus 로고
    • Changes in thymic function with age and during the treatment of HIV infection
    • Douek DC, McFarland RD, Keiser PH, et al. Changes in thymic function with age and during the treatment of HIV infection. Nature 1998; 396: 690-5.
    • (1998) Nature , vol.396 , pp. 690-5
    • Douek, D.C.1    Mcfarland, R.D.2    Keiser, P.H.3
  • 29
    • 33646689587 scopus 로고    scopus 로고
    • Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4- T cells in human immunodeficiency virus type 1 infection
    • Schacker TW, Brenchley JM, Beilman GJ, et al. Lymphatic tissue fibrosis is associated with reduced numbers of naive CD4- T cells in human immunodeficiency virus type 1 infection. Clin Vaccine Immunol 2006; 13:556-60.
    • (2006) Clin Vaccine Immunol , vol.13 , pp. 556-60
    • Schacker, T.W.1    Brenchley, J.M.2    Beilman, G.J.3
  • 30
    • 33749491636 scopus 로고    scopus 로고
    • Naive T-cell depletion related to infection by X4 human immunodeficiency virus type 1 in poor immunological responders to highly active antiretroviral therapy
    • Delobel P, Nugeyre MT, Cazabat M, et al. Naive T-cell depletion related to infection by X4 human immunodeficiency virus type 1 in poor immunological responders to highly active antiretroviral therapy. J Virol 2006; 80:10229-36.
    • (2006) J Virol , vol.80 , pp. 10229-36
    • Delobel, P.1    Nugeyre, M.T.2    Cazabat, M.3
  • 31
    • 33644748244 scopus 로고    scopus 로고
    • Naive T-cell dynamics in human immunodeficiency virus type 1 infection: Effects of highly active antiretroviral therapy provide insights into the mechanisms of naive T-cell depletion
    • Di Mascio M, Sereti I, Matthews LT, et al. Naive T-cell dynamics in human immunodeficiency virus type 1 infection: effects of highly active antiretroviral therapy provide insights into the mechanisms of naive T-cell depletion. J Virol 2006; 80:2665-74.
    • (2006) J Virol , vol.80 , pp. 2665-74
    • Di Mascio, M.1    Sereti, I.2    Matthews, L.T.3
  • 32
    • 0035905463 scopus 로고    scopus 로고
    • Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV
    • Kovacs JA, Lempicki RA, Sidorov IA, et al. Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV. J Exp Med 2001; 194:1731-41.
    • (2001) J Exp Med , vol.194 , pp. 1731-41
    • Kovacs, J.A.1    Lempicki, R.A.2    Sidorov, I.A.3
  • 33
    • 12944331410 scopus 로고    scopus 로고
    • Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4- and CD8- T cell turnover in HIV-infected patients
    • USA
    • Lempicki RA, Kovacs JA, Baseler MW, et al. Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4- and CD8- T cell turnover in HIV-infected patients. Proc Natl Acad SciUSA 2000; 97:13778-83.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 13778-83
    • Lempicki, R.A.1    Kovacs, J.A.2    Baseler, M.W.3
  • 34
    • 0035169609 scopus 로고    scopus 로고
    • Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy
    • Mohri H, Perelson AS, Tung K, et al. Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy. J Exp Med 2001; 194:1277-87.
    • (2001) J Exp Med , vol.194 , pp. 1277-87
    • Mohri, H.1    Perelson, A.S.2    Tung, K.3
  • 35
    • 20844450412 scopus 로고    scopus 로고
    • Peripheral S-phase T cells in HIV disease have a central memory phenotype and rarely have evidence of recent T cell receptor engagement
    • Sieg SF, Rodriguez B, Asaad R, Jiang W, Bazdar DA, Lederman MM. Peripheral S-phase T cells in HIV disease have a central memory phenotype and rarely have evidence of recent T cell receptor engagement. J Infect Dis 2005; 192:62-70.
    • (2005) J Infect Dis , vol.192 , pp. 62-70
    • Sieg, S.F.1    Rodriguez, B.2    Asaad, R.3    Jiang, W.4    Bazdar, D.A.5    Lederman, M.M.6
  • 36
    • 3843056825 scopus 로고    scopus 로고
    • Immune activation set point during early HIV infection predicts subsequent CD4- T-cell changes independent of viral load
    • Deeks SG, Kitchen CM, Liu L, et al. Immune activation set point during early HIV infection predicts subsequent CD4- T-cell changes independent of viral load. Blood 2004; 104:942-7.
    • (2004) Blood , vol.104 , pp. 942-7
    • Deeks, S.G.1    Kitchen, C.M.2    Liu, L.3
  • 37
    • 0030668834 scopus 로고    scopus 로고
    • Elevated CD38 antigen expression on CD8- T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4- cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression
    • Liu Z, Cumberland WG, Hultin LE, Prince HE, Detels R, Giorgi JV. Elevated CD38 antigen expression on CD8- T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4- cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression. J Acquir Immune Defic Syndr Hum Retrovirol 1997; 16:83-92.
    • (1997) J Acquir Immune Defic Syndr Hum Retrovirol , vol.16 , pp. 83-92
    • Liu, Z.1    Cumberland, W.G.2    Hultin, L.E.3    Prince, H.E.4    Detels, R.5    Giorgi, J.V.6
  • 38
    • 0037343278 scopus 로고    scopus 로고
    • Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia
    • Silvestri G, Sodora DL, Koup RA, et al. Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia. Immunity 2003; 18:441-52.
    • (2003) Immunity , vol.18 , pp. 441-52
    • Silvestri, G.1    Sodora, D.L.2    Koup, R.A.3
  • 39
    • 4644342929 scopus 로고    scopus 로고
    • CD4- T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract
    • Brenchley JM, Schacker TW, Ruff LE, et al. CD4- T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J Exp Med 2004; 200:749-59.
    • (2004) J Exp Med , vol.200 , pp. 749-59
    • Brenchley, J.M.1    Schacker, T.W.2    Ruff, L.E.3
  • 40
    • 0032540418 scopus 로고    scopus 로고
    • Gastrointestinal tract as a major site of CD4- T cell depletion and viral replication in SIV infection
    • Veazey RS, DeMaria M, Chalifoux LV, et al. Gastrointestinal tract as a major site of CD4- T cell depletion and viral replication in SIV infection. Science 1998; 280:427-31.
    • (1998) Science , vol.280 , pp. 427-31
    • Veazey, R.S.1    DeMaria, M.2    Chalifoux, L.V.3
  • 41
    • 34548413609 scopus 로고    scopus 로고
    • ProgressiveCD4- central memory T cell decline results in CD4- effector memory insufficiency and overt disease in chronic SIV infection
    • Okoye A, Meier-Schellersheim M, Brenchley JM, et al. ProgressiveCD4- central memory T cell decline results in CD4- effector memory insufficiency and overt disease in chronic SIV infection. J Exp Med 2007; 204: 2171-85.
    • (2007) J Exp Med , vol.204 , pp. 2171-85
    • Okoye, A.1    Meier-Schellersheim, M.2    Brenchley, J.M.3
  • 42
    • 34248400051 scopus 로고    scopus 로고
    • Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1
    • Biancotto A, Grivel JC, Iglehart SJ, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood 2007; 109:4272-9.
    • (2007) Blood , vol.109 , pp. 4272-9
    • Biancotto, A.1    Grivel, J.C.2    Iglehart, S.J.3
  • 43
    • 0037927824 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells
    • Cornish AL, Chong MM, Davey GM, et al. Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells. J Biol Chem 2003; 278:22755-61.
    • (2003) J Biol Chem , vol.278 , pp. 22755-61
    • Cornish, A.L.1    Chong, M.M.2    Davey, G.M.3
  • 44
    • 0034663932 scopus 로고    scopus 로고
    • Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/suppressors of cytokine signaling-1 transgenic mice
    • Fujimoto M, Naka T, Nakagawa R, et al. Defective thymocyte development and perturbed homeostasis of T cells in STAT-induced STAT inhibitor-1/ suppressors of cytokine signaling-1 transgenic mice. J Immunol 2000; 165:1799-806.
    • (2000) J Immunol , vol.165 , pp. 1799-806
    • Fujimoto, M.1    Naka, T.2    Nakagawa, R.3
  • 45
    • 33646874634 scopus 로고    scopus 로고
    • IL-7R - gene expression is inversely correlated with cell cycle progression in IL-7-stimulated T lymphocytes
    • Swainson L, Verhoeyen E, Cosset FL, Taylor N. IL-7R - gene expression is inversely correlated with cell cycle progression in IL-7-stimulated T lymphocytes. J Immunol 2006; 176:6702-8.
    • (2006) J Immunol , vol.176 , pp. 6702-8
    • Swainson, L.1    Verhoeyen, E.2    Cosset, F.L.3    Taylor, N.4
  • 46
    • 30744443482 scopus 로고    scopus 로고
    • IL-7 induces immunological improvement in SIV-infected rhesus macaques under antiviral therapy
    • Beq S, Nugeyre MT, Ho Tsong Fang R, et al. IL-7 induces immunological improvement in SIV-infected rhesus macaques under antiviral therapy. J Immunol 2006; 176:914-22.
    • (2006) J Immunol , vol.176 , pp. 914-22
    • Beq, S.1    Nugeyre, M.T.2    Ho Tsong Fang, R.3
  • 47
    • 0141889077 scopus 로고    scopus 로고
    • IL-7 stimulates T cell renewal without increasing viral replication in simian immunodeficiency virusinfected macaques
    • Nugeyre MT, Monceaux V, Beq S, et al. IL-7 stimulates T cell renewal without increasing viral replication in simian immunodeficiency virusinfected macaques. J Immunol 2003; 171:4447-53.
    • (2003) J Immunol , vol.171 , pp. 4447-53
    • Nugeyre, M.T.1    Monceaux, V.2    Beq, S.3
  • 48
    • 84863580407 scopus 로고    scopus 로고
    • Repeated r-hIL-7 doses improve T-cell recovery in HIV-1-infected patients enrolled in a phase I/II multicentric study [abstract 127]
    • (Los Angeles, CA), 25-28 February
    • Levy Y, Weiss L, Viard JP, et al. Repeated r-hIL-7 doses improve T-cell recovery in HIV-1-infected patients enrolled in a phase I/II multicentric study [abstract 127]. In: Program and abstracts of the 14th Conference on Retroviruses and Opportunistic Infections (Los Angeles, CA), 25-28 February 2007.
    • (2007) Program and abstracts of the 14th Conference on Retroviruses and Opportunistic Infections
    • Levy, Y.1    Weiss, L.2    Viard, J.P.3
  • 49
    • 33745250989 scopus 로고    scopus 로고
    • Interleukin-7 induces HIV replication in primary naive T cells through a nuclear factor of activated T cell (NFAT)-dependent pathway
    • Managlia EZ, Landay A, Al-Harthi L. Interleukin-7 induces HIV replication in primary naive T cells through a nuclear factor of activated T cell (NFAT)-dependent pathway. Virology 2006; 350:443-52.
    • (2006) Virology , vol.350 , pp. 443-52
    • Managlia, E.Z.1    Landay, A.2    Al-Harthi, L.3
  • 50
    • 0029868970 scopus 로고    scopus 로고
    • IL-7 up-regulates HIV-1 replication in naturally infected peripheral blood mononuclear cells
    • Smithgall MD, Wong JG, Critchett KE, Haffar OK. IL-7 up-regulates HIV-1 replication in naturally infected peripheral blood mononuclear cells. J Immunol 1996; 156:2324-30.
    • (1996) J Immunol , vol.156 , pp. 2324-30
    • Smithgall, M.D.1    Wong, J.G.2    Critchett, K.E.3    Haffar, O.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.