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Volumn 63, Issue 5, 2014, Pages 711-719

Nrf2 deficiency impairs the barrier function of mouse oesophageal epithelium

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ADENOSINE TRIPHOSPHATE; CLAUDIN 4; CYTOCHROME C OXIDASE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; OXIDOREDUCTASE; TRANSCRIPTION FACTOR NRF2;

EID: 84898000276     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2012-303731     Document Type: Article
Times cited : (77)

References (52)
  • 1
    • 19244366014 scopus 로고    scopus 로고
    • Pathophysiology of GERD: Esophageal epithelial defense
    • Orlando LA, Orlando RC. Pathophysiology of GERD: esophageal epithelial defense. Pract Gastroenterol 2004;28:16-57.
    • (2004) Pract Gastroenterol , vol.28 , pp. 16-57
    • Orlando, L.A.1    Orlando, R.C.2
  • 2
    • 78649748448 scopus 로고    scopus 로고
    • The integrity of the esophageal mucosa. Balance between offensive and defensive mechanisms
    • Orlando RC. The integrity of the esophageal mucosa. Balance between offensive and defensive mechanisms. Best Pract Res Clin Gastroenterol 2010;24:873-82.
    • (2010) Best Pract Res Clin Gastroenterol , vol.24 , pp. 873-882
    • Orlando, R.C.1
  • 3
    • 33847050801 scopus 로고    scopus 로고
    • Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
    • Kensler TW, Wakabayashi N, Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu Rev Pharmacol Toxicol 2007;47:89-116.
    • (2007) Annu Rev Pharmacol Toxicol , vol.47 , pp. 89-116
    • Kensler, T.W.1    Wakabayashi, N.2    Biswal, S.3
  • 4
    • 79952221884 scopus 로고    scopus 로고
    • Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo
    • Suzuki T, Maher J, Yamamoto M. Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo. Cancer Res 2011;71:1700-9.
    • (2011) Cancer Res , vol.71 , pp. 1700-1709
    • Suzuki, T.1    Maher, J.2    Yamamoto, M.3
  • 6
    • 84860476268 scopus 로고    scopus 로고
    • Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus
    • Chen H, Li J, Li H, et al. Transcript profiling identifies dynamic gene expression patterns and an important role for Nrf2/Keap1 pathway in the developing mouse esophagus. PLoS ONE 2012;7:e36504.
    • (2012) PLoS ONE , vol.7
    • Chen, H.1    Li, J.2    Li, H.3
  • 7
    • 80051983081 scopus 로고    scopus 로고
    • Deconstructing the skin: Cytoarchitectural determinants of epidermal morphogenesis
    • Simpson CL, Patel DM, Green KJ. Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis. Nat Rev Mol Cell Biol 2011;12:565-80.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 565-580
    • Simpson, C.L.1    Patel, D.M.2    Green, K.J.3
  • 8
    • 79958808930 scopus 로고    scopus 로고
    • ROS quenching potential of the epidermal corni fied cell envelope
    • Vermeij WP, Alia A, Backendorf C. ROS quenching potential of the epidermal corni fied cell envelope. J Invest Dermatol 2011;131:1435-41.
    • (2011) J Invest Dermatol , vol.131 , pp. 1435-1441
    • Vermeij, W.P.1    Alia, A.2    Backendorf, C.3
  • 11
    • 80054790884 scopus 로고    scopus 로고
    • Impact of Nrf2 on esophagus epithelium cornification
    • Wruck CJ, Wruck A, Brandenburg LO, et al. Impact of Nrf2 on esophagus epithelium cornification. Int J Dermatol 2011;50:1362-5.
    • (2011) Int J Dermatol , vol.50 , pp. 1362-1365
    • Wruck, C.J.1    Wruck, A.2    Brandenburg, L.O.3
  • 12
    • 79960830822 scopus 로고    scopus 로고
    • Claudins: Control of barrier function and regulation in response to oxidant stress
    • Overgaard CE, Daugherty BL, Mitchell LA, et al. Claudins: control of barrier function and regulation in response to oxidant stress. Antioxid Redox Signal 2011;15:1179-93.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 1179-1193
    • Overgaard, C.E.1    Daugherty, B.L.2    Mitchell, L.A.3
  • 13
    • 33947433224 scopus 로고    scopus 로고
    • Inflammation and oxidative stress in gastroesophageal reflux disease
    • DOI 10.3164/jcbn.40.13
    • Yoshida N. In flammation and oxidative stress in gastroesophageal re flux disease. J Clin Biochem Nutr 2007;40:13-23. (Pubitemid 46449683)
    • (2007) Journal of Clinical Biochemistry and Nutrition , vol.40 , Issue.1 , pp. 13-23
    • Yoshida, N.1
  • 14
    • 0034908033 scopus 로고    scopus 로고
    • Esophageal adenocarcinoma: A review and perspectives on the mechanism of carcinogenesis and chemoprevention
    • Chen X, Yang CS. Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention. Carcinogenesis 2001;22:1119-29. (Pubitemid 32737325)
    • (2001) Carcinogenesis , vol.22 , Issue.8 , pp. 1119-1129
    • Chen, X.1    Yang, C.S.2
  • 17
    • 77952931899 scopus 로고    scopus 로고
    • Evaluation of the heme oxygenase-1 expression in esophagitis and esophageal cancer induced by different reflux experimental models and diethylnitrosamine
    • Kruel CR, Pinto LF, Blanco TC, et al. Evaluation of the heme oxygenase-1 expression in esophagitis and esophageal cancer induced by different reflux experimental models and diethylnitrosamine. Acta Cir Bras 2010;25:304-10.
    • (2010) Acta Cir Bras , vol.25 , pp. 304-310
    • Kruel, C.R.1    Pinto, L.F.2    Blanco, T.C.3
  • 18
    • 67249112674 scopus 로고    scopus 로고
    • Metabolic stress evokes decreases in epithelial barrier function
    • Lewis K, McKay DM. Metabolic stress evokes decreases in epithelial barrier function. Ann N Y Acad Sci 2009;1165:327-37.
    • (2009) Ann N Y Acad Sci , vol.1165 , pp. 327-337
    • Lewis, K.1    McKay, D.M.2
  • 19
    • 52049094403 scopus 로고    scopus 로고
    • Oxidative stress induces gastric epithelial permeability through claudin-3
    • Hashimoto K, Oshima T, Tomita T, et al. Oxidative stress induces gastric epithelial permeability through claudin-3. Biochem Biophys Res Commun 2008;376:154-7.
    • (2008) Biochem Biophys Res Commun , vol.376 , pp. 154-157
    • Hashimoto, K.1    Oshima, T.2    Tomita, T.3
  • 21
    • 77149136056 scopus 로고    scopus 로고
    • Reactive nitrogen oxide species induce dilatation of the intercellular space of rat esophagus
    • Ito H, Iijima K, Ara N, et al. Reactive nitrogen oxide species induce dilatation of the intercellular space of rat esophagus. Scand J Gastroenterol 2010;45:282-91.
    • (2010) Scand J Gastroenterol , vol.45 , pp. 282-291
    • Ito, H.1    Iijima, K.2    Ara, N.3
  • 22
    • 53649090801 scopus 로고    scopus 로고
    • Luminal hydrochloric acid stimulates rapid transepithelial ion fluxes in rodent esophageal stratified squamous epithelium
    • Lin BR, Hsieh HT, Lee JM, et al. Luminal hydrochloric acid stimulates rapid transepithelial ion fluxes in rodent esophageal stratified squamous epithelium. J Physiol Pharmacol 2008;59:525-42.
    • (2008) J Physiol Pharmacol , vol.59 , pp. 525-542
    • Lin, B.R.1    Hsieh, H.T.2    Lee, J.M.3
  • 23
    • 77149159093 scopus 로고    scopus 로고
    • Acid and weakly acidic solutions impair mucosal integrity of distal exposed and proximal non-exposed human oesophagus
    • Farre R, Fornari F, Blondeau K, et al. Acid and weakly acidic solutions impair mucosal integrity of distal exposed and proximal non-exposed human oesophagus. Gut 2010;59:164-9.
    • (2010) Gut , vol.59 , pp. 164-169
    • Farre, R.1    Fornari, F.2    Blondeau, K.3
  • 24
    • 58149328569 scopus 로고    scopus 로고
    • Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1
    • Piantadosi CA, Carraway MS, Babiker A, et al. Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. Circ Res 2008;103:1232-40.
    • (2008) Circ Res , vol.103 , pp. 1232-1240
    • Piantadosi, C.A.1    Carraway, M.S.2    Babiker, A.3
  • 25
    • 34247211016 scopus 로고    scopus 로고
    • Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis
    • Wu CW, Ping YH, Yen JC, et al. Enhanced oxidative stress and aberrant mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells during methamphetamine induced apoptosis. Toxicol Appl Pharmacol 2007;220:243-51.
    • (2007) Toxicol Appl Pharmacol , vol.220 , pp. 243-251
    • Wu, C.W.1    Ping, Y.H.2    Yen, J.C.3
  • 26
    • 0029051550 scopus 로고
    • FK506 increases permeability in rat intestine by inhibiting mitochondrial function
    • Madsen KL, Yanchar NL, Sigalet DL, et al. FK506 increases permeability in rat intestine by inhibiting mitochondrial function. Gastroenterology 1995;109:107-14.
    • (1995) Gastroenterology , vol.109 , pp. 107-114
    • Madsen, K.L.1    Yanchar, N.L.2    Sigalet, D.L.3
  • 27
    • 0028609124 scopus 로고
    • ATP depletion: A novel method to study junctional properties in epithelial tissues. I. Rearrangement of the actin cytoskeleton
    • Bacallao R, Garfinkel A, Monke S, et al. ATP depletion: a novel method to study junctional properties in epithelial tissues. I. Rearrangement of the actin cytoskeleton. J Cell Sci 1994;107:3301-13.
    • (1994) J Cell Sci , vol.107 , pp. 3301-3313
    • Bacallao, R.1    Garfinkel, A.2    Monke, S.3
  • 28
    • 0028581961 scopus 로고
    • ATP depletion: A novel method to study junctional properties in epithelial tissues. II. Internalization of Na+,K(+)-ATPase and E-cadherin
    • Mandel LJ, Doctor RB, Bacallao R. ATP depletion: a novel method to study junctional properties in epithelial tissues. II. Internalization of Na+,K(+)-ATPase and E-cadherin. J Cell Sci 1994;107:3315-24.
    • (1994) J Cell Sci , vol.107 , pp. 3315-3324
    • Mandel, L.J.1    Doctor, R.B.2    Bacallao, R.3
  • 29
    • 42649130014 scopus 로고    scopus 로고
    • PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria
    • Lo SC, Hannink M. PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria. Exp Cell Res 2008;314:1789-803.
    • (2008) Exp Cell Res , vol.314 , pp. 1789-1803
    • Lo, S.C.1    Hannink, M.2
  • 30
    • 84863041323 scopus 로고    scopus 로고
    • Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-Nqo1 cascade
    • Kwon J, Han E, Bui CB, et al. Assurance of mitochondrial integrity and mammalian longevity by the p62-Keap1-Nrf2-Nqo1 cascade. EMBO Rep 2012;13:150-6.
    • (2012) EMBO Rep , vol.13 , pp. 150-156
    • Kwon, J.1    Han, E.2    Bui, C.B.3
  • 32
    • 84855215608 scopus 로고    scopus 로고
    • Acid modulates the squamous epithelial barrier function by modulating the localization of claudins in the superficial layers
    • Oshima T, Koseki J, Chen X, et al. Acid modulates the squamous epithelial barrier function by modulating the localization of claudins in the superficial layers. Lab Invest 2012;92:22-31.
    • (2012) Lab Invest , vol.92 , pp. 22-31
    • Oshima, T.1    Koseki, J.2    Chen, X.3
  • 33
    • 79960982538 scopus 로고    scopus 로고
    • Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins
    • Chen X, Oshima T, Tomita T, et al. Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins. Am J Physiol Gastrointest Liver Physiol 2011;301:G203-9.
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.301
    • Chen, X.1    Oshima, T.2    Tomita, T.3
  • 34
    • 84863978673 scopus 로고    scopus 로고
    • Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins
    • Chen X, Oshima T, Shan J, et al. Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins. Am J Physiol Gastrointest Liver Physiol 2012;303:G199-208.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.303
    • Chen, X.1    Oshima, T.2    Shan, J.3
  • 35
    • 84867317004 scopus 로고    scopus 로고
    • Identification of novel NRF2-regulated genes by ChIP-Seq: Influence on retinoid X receptor alpha
    • Chorley BN, Campbell MR, Wang X, et al. Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha. Nucleic Acids Res 2012;40:7416-29.
    • (2012) Nucleic Acids Res , vol.40 , pp. 7416-7429
    • Chorley, B.N.1    Campbell, M.R.2    Wang, X.3
  • 36
    • 77957237159 scopus 로고    scopus 로고
    • Global mapping of binding sites for Nrf2 identi fies novel targets in cell survival response through ChIP-Seq profiling and network analysis
    • Malhotra D, Portales-Casamar E, Singh A, et al. Global mapping of binding sites for Nrf2 identi fies novel targets in cell survival response through ChIP-Seq profiling and network analysis. Nucleic Acids Res 2010;38:5718-34.
    • (2010) Nucleic Acids Res , vol.38 , pp. 5718-5734
    • Malhotra, D.1    Portales-Casamar, E.2    Singh, A.3
  • 37
    • 34548850603 scopus 로고    scopus 로고
    • Enhancing expression of Nrf2-driven genes protects the blood-brain barrier after brain injury
    • DOI 10.1523/JNEUROSCI.1683-07.2007
    • Zhao J, Moore AN, Redell JB, et al. Enhancing expression of Nrf2-driven genes protects the blood brain barrier after brain injury. J Neurosci 2007;27:10240-8. (Pubitemid 47450456)
    • (2007) Journal of Neuroscience , vol.27 , Issue.38 , pp. 10240-10248
    • Zhao, J.1    Moore, A.N.2    Redell, J.B.3    Dash, P.K.4
  • 38
    • 77955097118 scopus 로고    scopus 로고
    • After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult
    • Arredondo F, Echeverry C, Abin-Carriquiry JA, et al. After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult. Free Radic Biol Med 2010;49:738-47.
    • (2010) Free Radic Biol Med , vol.49 , pp. 738-747
    • Arredondo, F.1    Echeverry, C.2    Abin-Carriquiry, J.A.3
  • 40
    • 65349095529 scopus 로고    scopus 로고
    • Quercetin enhances intestinal barrier function through the assembly of zonula [corrected] occludens-2, occludin, and claudin-1 and the expression of claudin-4 in Caco-2 cells
    • Suzuki T, Hara H. Quercetin enhances intestinal barrier function through the assembly of zonula [corrected] occludens-2, occludin, and claudin-1 and the expression of claudin-4 in Caco-2 cells. J Nutr 2009;139:965-74.
    • (2009) J Nutr , vol.139 , pp. 965-974
    • Suzuki, T.1    Hara, H.2
  • 41
    • 47549111114 scopus 로고    scopus 로고
    • Effect of quercetin, flavonoids and alpha-tocopherol, an antioxidant vitamin, on experimental reflux oesophagitis in rats
    • Rao CV, Vijayakumar M. Effect of quercetin, flavonoids and alpha-tocopherol, an antioxidant vitamin, on experimental reflux oesophagitis in rats. Eur J Pharmacol 2008;589:233-8.
    • (2008) Eur J Pharmacol , vol.589 , pp. 233-238
    • Rao, C.V.1    Vijayakumar, M.2
  • 42
    • 77954136996 scopus 로고    scopus 로고
    • Management of gastroesophageal re flux disease that does not respond well to proton pump inhibitors
    • Hershcovici T, Fass R. Management of gastroesophageal re flux disease that does not respond well to proton pump inhibitors. Curr Opin Gastroenterol 2010;26:367-78.
    • (2010) Curr Opin Gastroenterol , vol.26 , pp. 367-378
    • Hershcovici, T.1    Fass, R.2
  • 44
    • 68049104246 scopus 로고    scopus 로고
    • Evolving issues in the management of reflux disease?
    • Yuan Y, Hunt RH. Evolving issues in the management of reflux disease? Curr Opin Gastroenterol 2009;25:342-51.
    • (2009) Curr Opin Gastroenterol , vol.25 , pp. 342-351
    • Yuan, Y.1    Hunt, R.H.2
  • 45
    • 66249084112 scopus 로고    scopus 로고
    • Radiofrequency ablation in Barrett's esophagus with dysplasia
    • Shaheen NJ, Sharma P, Overholt BF, et al. Radiofrequency ablation in Barrett's esophagus with dysplasia. N Engl J Med 2009;360:2277-88.
    • (2009) N Engl J Med , vol.360 , pp. 2277-2288
    • Shaheen, N.J.1    Sharma, P.2    Overholt, B.F.3
  • 46
    • 80051483372 scopus 로고    scopus 로고
    • Durability of radiofrequency ablation in Barrett's esophagus with dysplasia
    • Shaheen NJ, Overholt BF, Sampliner RE, et al. Durability of radiofrequency ablation in Barrett's esophagus with dysplasia. Gastroenterology 2011;141:460-8.
    • (2011) Gastroenterology , vol.141 , pp. 460-468
    • Shaheen, N.J.1    Overholt, B.F.2    Sampliner, R.E.3
  • 47
    • 66249135317 scopus 로고    scopus 로고
    • Properties of the neosquamous epithelium after radiofrequency ablation of Barrett's esophagus containing neoplasia
    • Pouw RE, Gondrie JJ, Rygiel AM, et al. Properties of the neosquamous epithelium after radiofrequency ablation of Barrett's esophagus containing neoplasia. Am J Gastroenterol 2009;104:1366-73.
    • (2009) Am J Gastroenterol , vol.104 , pp. 1366-1373
    • Pouw, R.E.1    Gondrie, J.J.2    Rygiel, A.M.3
  • 48
    • 58149088996 scopus 로고    scopus 로고
    • Histopathology of Barrett's esophagus after ablation and endoscopic mucosal resection therapy
    • Odze RD, Lauwers GY. Histopathology of Barrett's esophagus after ablation and endoscopic mucosal resection therapy. Endoscopy 2008;40:1008-15.
    • (2008) Endoscopy , vol.40 , pp. 1008-1015
    • Odze, R.D.1    Lauwers, G.Y.2
  • 49
    • 84864060477 scopus 로고    scopus 로고
    • Long-term results of ablation with antireflux surgery for Barrett's esophagus: A clinical and molecular biologic study
    • Kauttu T, Rasanen J, Krogerus L, et al. Long-term results of ablation with antireflux surgery for Barrett's esophagus: a clinical and molecular biologic study. Surg Endosc 2012;26:1892-7.
    • (2012) Surg Endosc , vol.26 , pp. 1892-1897
    • Kauttu, T.1    Rasanen, J.2    Krogerus, L.3
  • 50
    • 84897974814 scopus 로고    scopus 로고
    • Sub-optimal barrier function in neosquamous epithelium following ablative therapy
    • Jovov B, Tobey N, Shaheen NJ, et al. Sub-optimal barrier function in neosquamous epithelium following ablative therapy. Gastroenterology 2011;140:S218.
    • (2011) Gastroenterology , vol.140
    • Jovov, B.1    Tobey, N.2    Shaheen, N.J.3
  • 51
    • 79955834680 scopus 로고    scopus 로고
    • Bioavailability of Sulforaphane from two broccoli sprout beverages: Results of a short-term, cross-over clinical trial in Qidong, China
    • Egner PA, Chen JG, Wang JB, et al. Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China. Cancer Prev Res (Phila) 2011;4:384-95.
    • (2011) Cancer Prev Res (Phila) , vol.4 , pp. 384-395
    • Egner, P.A.1    Chen, J.G.2    Wang, J.B.3
  • 52
    • 79960855656 scopus 로고    scopus 로고
    • Bardoxolone methyl and kidney function in CKD with type 2 diabetes
    • Pergola PE, Raskin P, Toto RD, et al. Bardoxolone methyl and kidney function in CKD with type 2 diabetes. N Engl J Med 2011;365:327-36.
    • (2011) N Engl J Med , vol.365 , pp. 327-336
    • Pergola, P.E.1    Raskin, P.2    Toto, R.D.3


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