Cysteine-rich protein 61 (CCN1) domain-specific stimulation of matrix metalloproteinase-1 expression through αVβ3 integrin in human skin fibroblasts

Journal of Biological Chemistry

Volumn 288, Issue 17, 2013, Pages 12386-12394

  Qin, Zhaoping ^a   Fisher, Gary J ^a   Quan, Taihao ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN DEGRADATIONS; EXTRACELLULAR MATRICES; FUNCTIONAL INTERACTION; HUMAN DERMAL FIBROBLASTS; HUMAN SKIN FIBROBLAST; MATRIX METALLOPROTEINASE-1; MATRIX METALLOPROTEINASES; TYPE I COLLAGEN FIBRILS;

AMINO ACIDS; CELL CULTURE; COLLAGEN; FIBROBLASTS; THREE DIMENSIONAL; TISSUE;

ENZYME INHIBITION;

COLLAGEN FIBRIL; COLLAGEN TYPE 1; CYSTEINE; CYSTEINE RICH PROTEIN 61; INTERSTITIAL COLLAGENASE; SOMATOMEDIN BINDING PROTEIN; THROMBOSPONDIN 1; VITRONECTIN RECEPTOR; VON WILLEBRAND FACTOR;

AGING; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN DOMAIN; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SKIN FIBROBLAST; THROMBOSPONDIN TYPE I REPEAT; UPREGULATION; VON WILLEBRAND FACTOR TYPE C REPEAT;

ADULT; AGING; COLLAGEN TYPE I; CYSTEINE-RICH PROTEIN 61; DERMIS; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INTEGRIN ALPHAVBETA3; MALE; MATRIX METALLOPROTEINASE 1; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS;

EID: 84876894055     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.424358     Document Type: Article

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