Inorganic phosphate blocks binding of pre-miRNA to Dicer-2 via its PAZ domain

EMBO Journal

Volumn 33, Issue 4, 2014, Pages 371-384

  Fukunaga, Ryuya ^a,b   Colpan, Cansu ^a   Han, Bo W ^a   Zamore, Phillip D ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dicer; DsRNA; M iRNA; Phosphate; SiRNA

Indexed keywords

ADENOSINE TRIPHOSPHATE; DICER; MICRORNA; MUTANT PROTEIN; PHOSPHATE; PROTEIN DICER 2; UNCLASSIFIED DRUG;

ARTICLE; DROSOPHILA; ENZYME SPECIFICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN RNA BINDING; RNA PROCESSING;

AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; MICRORNAS; MUTAGENESIS, SITE-DIRECTED; PHOSPHATES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RIBONUCLEASE III; RNA HELICASES; RNA, DOUBLE-STRANDED; SUBSTRATE SPECIFICITY;

EID: 84897888892     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1002/embj.201387176     Document Type: Article

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