The plant decapeptide OSIP108 prevents copper-induced apoptosis in yeast and human cells

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1843, Issue 6, 2014, Pages 1207-1215

  Spincemaille, Pieter ^a   Chandhok, Gursimran ^b   Newcomb, Benjamin ^c   Verbeek, Jef ^d   Vriens, Kim ^a   Zibert, Andree ^b   Schmidt, Hartmut ^b   Hannun, Yusuf A ^c   van Pelt, Jos ^d   Cassiman, David ^d   Cammue, Bruno P A ^a,e   Thevissen, Karin ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c STONY BROOK UNIVERSITY   (United States)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

Apoptosis; Ceramide; Copper; OSIP108; Saccharomyces cerevisiae

Indexed keywords

3 KETODIHYDROSPHINGOSINE REDUCTASE; BIOLOGICAL MARKER; CASPASE; CASPASE LIKE PROTEASE; CERAMIDE; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; DIHYDROCERAMIDE; DIHYDROSPHINGOSINE 1 PHOSPHATE; OSIP108 PEPTIDE; PEPTIDE; PHOSPHOETHANOLAMINE; REACTIVE OXYGEN METABOLITE; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE 1 PHOSPHATE; UNCLASSIFIED DRUG;

APOPTOSIS; ARABIDOPSIS THALIANA; ARTICLE; CELL PROTECTION; CELL STRAIN HEPG2; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ELECTRON MICROSCOPY; ENZYME ACTIVITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRION; NICK END LABELING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; WILSON DISEASE;

APOPTOSIS; CERAMIDE; COPPER; OSIP108; SACCHAROMYCES CEREVISIAE;

APOPTOSIS; ARABIDOPSIS; COPPER; HEP G2 CELLS; HUMANS; MICROSCOPY, ELECTRON; MITOCHONDRIA; OLIGOPEPTIDES; OXIDATIVE STRESS; SACCHAROMYCES CEREVISIAE; SPHINGOLIPIDS;

EID: 84897831558     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2014.03.004     Document Type: Article

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