Abnormal chondrocyte apoptosis in the cartilage growth plate is influenced by genetic background and deletion of CHOP in a targeted mouse model of pseudoachondroplasia

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Piróg, Katarzyna A ^a   Irman, Andreja ^b   Young, Siobhan ^b   Halai, Poonam ^b   Bell, Peter A ^a   Boot Handford, Raymond P ^b   Briggs, Michael D ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARTILAGE OLIGOMERIC MATRIX PROTEIN; DECORIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PERILIPIN; THROMBOSPONDIN 1; DDIT3 PROTEIN, MOUSE;

ACHONDROPLASIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE GROWTH; BONE LENGTH; BONE MATURATION; CARTILAGE; CARTILAGE CELL; CELL PROLIFERATION; CHOP GENE; CONTROLLED STUDY; DISEASE MODEL; GENE DELETION; GROWTH PLATE; HOMOZYGOSITY; MOUSE; NONHUMAN; PHENOTYPE; PSEUDOACHONDROPLASIA; SKULL; TIBIA; ANIMAL; BONE; C57BL MOUSE; CYTOLOGY; GENETICS; HOMOZYGOTE; KNOCKOUT MOUSE; METABOLISM; MUTANT MOUSE STRAIN; MUTATION; PATHOLOGY; STERNUM;

ACHONDROPLASIA; ANIMALS; APOPTOSIS; BONE AND BONES; CARTILAGE; CELL PROLIFERATION; CHONDROCYTES; DISEASE MODELS, ANIMAL; GROWTH PLATE; HOMOZYGOTE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, MUTANT STRAINS; MUTATION; PHENOTYPE; TRANSCRIPTION FACTOR CHOP; XIPHOID BONE;

EID: 84897804791     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0085145     Document Type: Article

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