An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasia

Cell Stress and Chaperones

Volumn 15, Issue 6, 2010, Pages 835-849

  Nundlall, Seema ^a   Rajpar, M Helen ^a   Bell, Peter A ^a   Clowes, Christopher ^a   Zeeff, Leo A H ^b   Gardner, Benjamin ^a   Thornton, David J ^a   Boot Handford, Raymond P ^a   Briggs, Michael D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

ARMET; Chemical chaperones; Chondrodysplasia; CRELD2; Matrilin 3; Mouse model; Unfolded protein response

Indexed keywords

ARGININE; CHAPERONE; CYSTEINE; EPIDERMAL GROWTH FACTOR; MATRILIN 3; MUTANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CARTILAGE CELL; CELL MUTANT; CHO CELL; CHONDRODYSPLASIA; CONTROLLED STUDY; DYSPLASIA; ENDOPLASMIC RETICULUM STRESS; EPIPHYSIS DISEASE; GENE EXPRESSION PROFILING; GROWTH PLATE; METAPHYSIS; MOUSE; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIB; STERNUM; TIBIA; UPREGULATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; CARTILAGE; CHONDROCYTES; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION PROFILING; MICE; MUTATION; NERVE GROWTH FACTORS; OSTEOCHONDRODYSPLASIAS; PHENOTYPE; PHENYLBUTYRATES; RIBS; TIME FACTORS; UNFOLDED PROTEIN RESPONSE; UP-REGULATION;

MUS;

EID: 78149468680     PISSN: 13558145     EISSN: 14661268     Source Type: Journal    
DOI: 10.1007/s12192-010-0193-y     Document Type: Article

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