Genetic Background Has a Major Effect on the Penetrance and Severity of Craniofacial Defects in Mice Heterozygous for the Gene Encoding the Nucleolar Protein Treacle

Developmental Dynamics

Volumn 229, Issue 4, 2004, Pages 907-914

  Dixon, Jill ^a   Dixon, Michael James ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Craniofacial defects; Genetic background; Phenotypic variation; Tcof1; Treacher Collins syndrome

Indexed keywords

GENE PRODUCT; PROTEIN TREACLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MALFORMATION; COMORBIDITY; CRANIOFACIAL MALFORMATION; DISEASE MODEL; DISEASE SEVERITY; EMBRYO; EYE MALFORMATION; FINGER MALFORMATION; GENE MUTATION; HETEROZYGOTE; LETHAL MUTANT; LONG BONE; MANDIBULOFACIAL DYSOSTOSIS; MAXILLA HYPOPLASIA; MOUSE; MOUSE STRAIN; NEURAL TUBE DEFECT; NONHUMAN; NOSE MALFORMATION; PENETRANCE; PHENOTYPE; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROGENY; PROTEIN FUNCTION; RIB MALFORMATION;

ANIMALS; EMBRYO; FEMALE; HETEROZYGOTE; HIGH MOBILITY GROUP PROTEINS; IMMUNOCHEMISTRY; MALE; MANDIBULOFACIAL DYSOSTOSIS; MICE; MICE, INBRED STRAINS; NEOPLASM PROTEINS; NEURAL CREST; NUCLEAR PROTEINS; PENETRANCE; PHOSPHOPROTEINS; TRANSCRIPTION FACTORS;

EID: 1842509200     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.20004     Document Type: Article

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