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Volumn 63, Issue SUPPL., 2014, Pages

Structure, function, and pharmacology of NMDA receptor channels

Author keywords

Channel blocker; Glutamate receptor; Ion channel; NMDA receptor; Pharmacology; Synaptic transmission

Indexed keywords

N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROPROTECTIVE AGENT;

EID: 84897608820     PISSN: 08628408     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (245)

References (99)
  • 5
    • 0033636314 scopus 로고    scopus 로고
    • Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor, crystal structures of the GluR2 ligand binding core
    • ARMSTRONG N, GOUAUX E, Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor, crystal structures of the GluR2 ligand binding core. Neuron 28, 165-181, 2000.
    • (2000) Neuron , vol.28 , pp. 165-181
    • Armstrong, N.1    Gouaux, E.2
  • 6
    • 0037312558 scopus 로고    scopus 로고
    • Activation of NR1/NR2B NMDA receptors
    • BANKE TG, TRAYNELIS SF, Activation of NR1/NR2B NMDA receptors. Nat Neurosci 6, 144-152, 2003.
    • (2003) Nat Neurosci , vol.6 , pp. 144-152
    • Banke, T.G.1    Traynelis, S.F.2
  • 8
    • 0025082936 scopus 로고
    • A kinetic analysis of the modulation of N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones
    • BENVENISTE M, CLEMENTS J, VYKLICKY L JR, MAYER ML, A kinetic analysis of the modulation of N-methyl-D-aspartic acid receptors by glycine in mouse cultured hippocampal neurones. J Physiol 428, 333-357, 1990.
    • (1990) J Physiol , vol.428 , pp. 333-357
    • Benveniste, M.1    Clements, J.2    Vyklicky, L.J.R.3    Mayer, M.L.4
  • 12
    • 0026543243 scopus 로고
    • Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit
    • BURNASHEV N, MONYER H, SEEBURG PH, SAKMANN B, Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit. Neuron 8, 189-198, 1992a.
    • (1992) Neuron , vol.8 , pp. 189-198
    • Burnashev, N.1    Monyer, H.2    Seeburg, P.H.3    Sakmann, B.4
  • 16
    • 23944511459 scopus 로고    scopus 로고
    • Pharmacological implications of two distinct mechanisms of interaction of memantine with N-methyl-D-aspartate-gated channels
    • CHEN HS, LIPTON SA, Pharmacological implications of two distinct mechanisms of interaction of memantine with N-methyl-D-aspartate-gated channels. J Pharmacol Exp Ther 314, 961-971, 2005.
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 961-971
    • Chen, H.S.1    Lipton, S.A.2
  • 18
    • 0033015733 scopus 로고    scopus 로고
    • Molecular evolution of glutamate receptors, a primitive signaling mechanism that existed before plants and animals diverged
    • CHIU J, DESALLE R, LAM HM, MEISEL L, CORUZZI G, Molecular evolution of glutamate receptors, a primitive signaling mechanism that existed before plants and animals diverged. Mol Biol Evol 16, 826-838, 1999.
    • (1999) Mol Biol Evol , vol.16 , pp. 826-838
    • Chiu, J.1    Desalle, R.2    Lam, H.M.3    Meisel, L.4    Coruzzi, G.5
  • 19
    • 0025607259 scopus 로고
    • The effect of agonist concentration, membrane voltage and calcium on N-methyl-D-aspartate receptor desensitization
    • CLARK GD, CLIFFORD DB, ZORUMSKI CF, The effect of agonist concentration, membrane voltage and calcium on N-methyl-D-aspartate receptor desensitization. Neuroscience 39, 787-797, 1990.
    • (1990) Neuroscience , vol.39 , pp. 787-797
    • Clark, G.D.1    Clifford, D.B.2    Zorumski, C.F.3
  • 20
    • 0025944430 scopus 로고
    • Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-D-aspartate receptor
    • CLEMENTS JD, WESTBROOK GL, Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-D-aspartate receptor. Neuron 7, 605-613, 1991.
    • (1991) Neuron , vol.7 , pp. 605-613
    • Clements, J.D.1    Westbrook, G.L.2
  • 21
    • 70350452578 scopus 로고    scopus 로고
    • (NMDA) receptor NR2 subunit selectivity of a series of novel piperazine-2,3-dicarboxylate derivatives, preferential blockade of extrasynaptic NMDA receptors in the rat hippocampal CA3-CA1 synapse
    • N-methyl-D-aspartate
    • COSTA BM, FENG B, TSINTSADZE TS, MORLEY RM, IRVINE MW, TSINTSADZE V, LOZOVAYA NA, JANE DE, MONAGHAN DT, N-methyl-D-aspartate (NMDA) receptor NR2 subunit selectivity of a series of novel piperazine-2,3-dicarboxylate derivatives, preferential blockade of extrasynaptic NMDA receptors in the rat hippocampal CA3-CA1 synapse. J Pharmacol Exp Ther 331, 618-626, 2009.
    • (2009) J Pharmacol Exp Ther , vol.331 , pp. 618-626
    • Costa, B.M.1    Feng, B.2    Tsintsadze, T.S.3    Morley, R.M.4    Irvine, M.W.5    Tsintsadze, V.6    Lozovaya, N.A.7    Jane, D.E.8    Monaghan, D.T.9
  • 25
    • 51849143750 scopus 로고    scopus 로고
    • Activation of recombinant NR1/NR2C NMDA receptors
    • DRAVID SM, PRAKASH A, TRAYNELIS SF, Activation of recombinant NR1/NR2C NMDA receptors. J Physiol 586, 4425-4439, 2008.
    • (2008) J Physiol , vol.586 , pp. 4425-4439
    • Dravid, S.M.1    Prakash, A.2    Traynelis, S.F.3
  • 26
    • 14944364531 scopus 로고    scopus 로고
    • Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles
    • ERREGER K, DRAVID SM, BANKE TG, WYLLIE DJ, TRAYNELIS SF, Subunit-specific gating controls rat NR1/NR2A and NR1/NR2B NMDA channel kinetics and synaptic signalling profiles. J Physiol 563, 345-358, 2005.
    • (2005) J Physiol , vol.563 , pp. 345-358
    • Erreger, K.1    Dravid, S.M.2    Banke, T.G.3    Wyllie, D.J.4    Traynelis, S.F.5
  • 28
    • 13844253597 scopus 로고    scopus 로고
    • The effect of competitive antagonist chain length on NMDA receptor subunit selectivity
    • FENG B, MORLEY RM, JANE DE, MONAGHAN DT, The effect of competitive antagonist chain length on NMDA receptor subunit selectivity. Neuropharmacology 48, 354-359, 2005.
    • (2005) Neuropharmacology , vol.48 , pp. 354-359
    • Feng, B.1    Morley, R.M.2    Jane, D.E.3    Monaghan, D.T.4
  • 29
    • 27744500994 scopus 로고    scopus 로고
    • Subunit arrangement and function in NMDA receptors
    • FURUKAWA H, SINGH SK, MANCUSSO R, GOUAUX E, Subunit arrangement and function in NMDA receptors. Nature 438, 185-192, 2005.
    • (2005) Nature , vol.438 , pp. 185-192
    • Furukawa, H.1    Singh, S.K.2    Mancusso, R.3    Gouaux, E.4
  • 30
    • 63049139659 scopus 로고    scopus 로고
    • Potency, voltage-dependency, agonist concentration-dependency, blocking kinetics and partial untrapping of the uncompetitive N-methyl-D-aspartate (NMDA) channel blocker memantine at human NMDA (GluN1/GluN2A) receptors
    • GILLING KE, JATZKE C, HECHENBERGER M, PARSONS CG, Potency, voltage-dependency, agonist concentration-dependency, blocking kinetics and partial untrapping of the uncompetitive N-methyl-D-aspartate (NMDA) channel blocker memantine at human NMDA (GluN1/GluN2A) receptors. Neuropharmacology 56, 866-875, 2009.
    • (2009) Neuropharmacology , vol.56 , pp. 866-875
    • Gilling, K.E.1    Jatzke, C.2    Hechenberger, M.3    Parsons, C.G.4
  • 31
    • 79952411415 scopus 로고    scopus 로고
    • Structural and mechanistic determinants of a novel site for noncompetitive inhibition of GluN2D-containing NMDA receptors
    • HANSEN KB, TRAYNELIS SF, Structural and mechanistic determinants of a novel site for noncompetitive inhibition of GluN2D-containing NMDA receptors. J Neurosci 31, 3650-3661, 2011.
    • (2011) J Neurosci , vol.31 , pp. 3650-3661
    • Hansen, K.B.1    Traynelis, S.F.2
  • 32
    • 84860321928 scopus 로고    scopus 로고
    • Subunit-selective allosteric inhibition of glycine binding to NMDA receptors
    • HANSEN KB, OGDEN KK, TRAYNELIS SF, Subunit-selective allosteric inhibition of glycine binding to NMDA receptors. J Neurosci 32, 6197-6208, 2012.
    • (2012) J Neurosci , vol.32 , pp. 6197-6208
    • Hansen, K.B.1    Ogden, K.K.2    Traynelis, S.F.3
  • 33
    • 84867322523 scopus 로고    scopus 로고
    • K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus, a microelectrode biosensor study
    • HEINRICH A, ANDO RD, TURI G, ROZSA B, SPERLAGH B, K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus, a microelectrode biosensor study. Br J Pharmacol 167, 1003-1020, 2012.
    • (2012) Br J Pharmacol , vol.167 , pp. 1003-1020
    • Heinrich, A.1    Ando, R.D.2    Turi, G.3    Rozsa, B.4    Sperlagh, B.5
  • 34
    • 34848821581 scopus 로고    scopus 로고
    • Extracellular glutamate concentration in hippocampal slice
    • HERMAN MA, JAHR CE, Extracellular glutamate concentration in hippocampal slice. J Neurosci 27, 9736-9741, 2007.
    • (2007) J Neurosci , vol.27 , pp. 9736-9741
    • Herman, M.A.1    Jahr, C.E.2
  • 35
    • 84858170245 scopus 로고    scopus 로고
    • Distribution of extracellular glutamate in the neuropil of hippocampus
    • HERMAN MA, NAHIR B, JAHR CE, Distribution of extracellular glutamate in the neuropil of hippocampus. PLoS One 6, e26501, 2011.
    • (2011) PLoS One 6, e26501
    • Herman, M.A.1    Nahir, B.2    Jahr, C.E.3
  • 36
    • 9244224117 scopus 로고    scopus 로고
    • Molecular mechanism of pregnenolone sulfate action at NR1/NR2B receptors
    • HORAK M, VLCEK K, PETROVIC M, CHODOUNSKA H, VYKLICKY L JR, Molecular mechanism of pregnenolone sulfate action at NR1/NR2B receptors. J Neurosci 24, 10318-10325, 2004.
    • (2004) J Neurosci , vol.24 , pp. 10318-10325
    • Horak, M.1    Vlcek, K.2    Petrovic, M.3    Chodounska, H.4    Vyklicky, L.J.R.5
  • 37
    • 29744463364 scopus 로고    scopus 로고
    • Subtype-dependence of N-methyl-D-aspartate receptor modulation by pregnenolone sulfate
    • HORAK M, VLCEK K, CHODOUNSKA H, VYKLICKY L JR, Subtype-dependence of N-methyl-D-aspartate receptor modulation by pregnenolone sulfate. Neuroscience 137, 93-102, 2006.
    • (2006) Neuroscience , vol.137 , pp. 93-102
    • Horak, M.1    Vlcek, K.2    Chodounska, H.3    Vyklicky, L.J.R.4
  • 38
    • 0018170634 scopus 로고
    • Changes in free amino acids of cerebrospinal fluid and plasma in various neurological diseases
    • IIJIMA K, TAKASE S, TSUMURAYA K, ENDO M, ITAHARA K, Changes in free amino acids of cerebrospinal fluid and plasma in various neurological diseases. Tohoku J Exp Med 126, 133-150, 1978.
    • (1978) Tohoku J Exp Med , vol.126 , pp. 133-150
    • Iijima, K.1    Takase, S.2    Tsumuraya, K.3    Endo, M.4    Itahara, K.5
  • 41
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • JOHNSON JW, ASCHER P, Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325, 529-531, 1987.
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 43
    • 46849097142 scopus 로고    scopus 로고
    • NMDA receptors in clinical neurology, excitatory times ahead
    • KALIA LV, KALIA SK, SALTER MW, NMDA receptors in clinical neurology, excitatory times ahead. Lancet Neurol 7, 742-755, 2008.
    • (2008) Lancet Neurol , vol.7 , pp. 742-755
    • Kalia, L.V.1    Kalia, S.K.2    Salter, M.W.3
  • 44
    • 79960417429 scopus 로고    scopus 로고
    • Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors
    • KARAKAS E, SIMOROWSKI N, FURUKAWA H, Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors. Nature 475, 249-253, 2011.
    • (2011) Nature , vol.475 , pp. 249-253
    • Karakas, E.1    Simorowski, N.2    Furukawa, H.3
  • 45
    • 19444366505 scopus 로고    scopus 로고
    • Identification of subunit- and antagonist-specific amino acid residues in the N-Methyl-D-aspartate receptor glutamatebinding pocket
    • KINARSKY L, FENG B, SKIFTER DA, MORLEY RM, SHERMAN S, JANE DE, MONAGHAN DT, Identification of subunit- and antagonist-specific amino acid residues in the N-Methyl-D-aspartate receptor glutamatebinding pocket. J Pharmacol Exp Ther 313, 1066-1074, 2005.
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 1066-1074
    • Kinarsky, L.1    Feng, B.2    Skifter, D.A.3    Morley, R.M.4    Sherman, S.5    Jane, D.E.6    Monaghan, D.T.7
  • 46
    • 0023754192 scopus 로고
    • Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes
    • KLECKNER NW, DINGLEDINE R, Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science 241, 835-837, 1988.
    • (1988) Science , vol.241 , pp. 835-837
    • Kleckner, N.W.1    Dingledine, R.2
  • 47
    • 0027339892 scopus 로고
    • Determinants of Ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels, diversity by RNA editing
    • KOHLER M, BURNASHEV N, SAKMANN B, SEEBURG PH, Determinants of Ca2+ permeability in both TM1 and TM2 of high affinity kainate receptor channels, diversity by RNA editing. Neuron 10, 491-500, 1993.
    • (1993) Neuron , vol.10 , pp. 491-500
    • Kohler, M.1    Burnashev, N.2    Sakmann, B.3    Seeburg, P.H.4
  • 48
    • 72749125663 scopus 로고    scopus 로고
    • Temperature dependence of N-methyl-Daspartate receptor channels and N-methyl-D-aspartate receptor excitatory postsynaptic currents
    • KORINEK M, SEDLACEK M, CAIS O, DITTERT I, VYKLICKY L JR, Temperature dependence of N-methyl-Daspartate receptor channels and N-methyl-D-aspartate receptor excitatory postsynaptic currents. Neuroscience 165, 736-748, 2010.
    • (2010) Neuroscience , vol.165 , pp. 736-748
    • Korinek, M.1    Sedlacek, M.2    Cais, O.3    Dittert, I.4    Vyklicky, L.J.R.5
  • 49
    • 0031048111 scopus 로고    scopus 로고
    • Psychotogenicity and N-methyl-D-aspartate receptor antagonism, implications for neuroprotective pharmacotherapy
    • KORNHUBER J, WELLER M, Psychotogenicity and N-methyl-D-aspartate receptor antagonism, implications for neuroprotective pharmacotherapy. Biol Psychiatry 41, 135-144, 1997.
    • (1997) Biol Psychiatry , vol.41 , pp. 135-144
    • Kornhuber, J.1    Weller, M.2
  • 50
    • 63849213773 scopus 로고    scopus 로고
    • Mg2+ imparts NMDA receptor subtype selectivity to the Alzheimer's drug memantine
    • KOTERMANSKI SE, JOHNSON JW, Mg2+ imparts NMDA receptor subtype selectivity to the Alzheimer's drug memantine. J Neurosci 29, 2774-2779, 2009.
    • (2009) J Neurosci , vol.29 , pp. 2774-2779
    • Kotermanski, S.E.1    Johnson, J.W.2
  • 51
    • 0025951641 scopus 로고
    • Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism
    • LEGENDRE P, WESTBROOK GL, Ifenprodil blocks N-methyl-D-aspartate receptors by a two-component mechanism. Mol Pharmacol 40, 289-298, 1991.
    • (1991) Mol Pharmacol , vol.40 , pp. 289-298
    • Legendre, P.1    Westbrook, G.L.2
  • 52
    • 0026601970 scopus 로고
    • NMDA channel behavior depends on agonist affinity
    • LESTER RA, JAHR CE, NMDA channel behavior depends on agonist affinity. J Neurosci 12, 635-643, 1992.
    • (1992) J Neurosci , vol.12 , pp. 635-643
    • Lester, R.A.1    Jahr, C.E.2
  • 53
    • 0025186752 scopus 로고
    • Noncompetitive excitatory amino acid receptor antagonists
    • LODGE D, JOHNSON KM, Noncompetitive excitatory amino acid receptor antagonists. Trends Pharmacol Sci 11, 81-86, 1990.
    • (1990) Trends Pharmacol Sci , vol.11 , pp. 81-86
    • Lodge, D.1    Johnson, K.M.2
  • 55
    • 36248982122 scopus 로고    scopus 로고
    • Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment
    • LONG SB, TAO X, CAMPBELL EB, MACKINNON R, Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment. Nature 450, 376-382, 2007.
    • (2007) Nature , vol.450 , pp. 376-382
    • Long, S.B.1    Campbell, T.A.O.X.2    Mackinnon, E.B.R.3
  • 56
    • 0036483593 scopus 로고    scopus 로고
    • The structure and function of glutamate receptor ion channels
    • MADDEN DR, The structure and function of glutamate receptor ion channels. Nat Rev Neurosci 3, 91-101, 2002.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 91-101
    • Madden, D.R.1
  • 57
    • 0036185532 scopus 로고    scopus 로고
    • Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids
    • MALAYEV A, GIBBS TT, FARB DH, Inhibition of the NMDA response by pregnenolone sulphate reveals subtype selective modulation of NMDA receptors by sulphated steroids. Br J Pharmacol 135, 901-909, 2002.
    • (2002) Br J Pharmacol , vol.135 , pp. 901-909
    • Malayev, A.1    Gibbs, T.T.2    Farb, D.H.3
  • 59
    • 0043180531 scopus 로고    scopus 로고
    • Excitotoxic and excitoprotective mechanisms, abundant targets for the prevention and treatment of neurodegenerative disorders
    • MATTSON MP, Excitotoxic and excitoprotective mechanisms, abundant targets for the prevention and treatment of neurodegenerative disorders. Neuromolecular Med 3, 65-94, 2003.
    • (2003) Neuromolecular Med , vol.3 , pp. 65-94
    • Mattson, M.P.1
  • 60
    • 13844266202 scopus 로고    scopus 로고
    • Crystal structures of the GluR5 and GluR6 ligand binding cores, molecular mechanisms underlying kainate receptor selectivity
    • MAYER ML, Crystal structures of the GluR5 and GluR6 ligand binding cores, molecular mechanisms underlying kainate receptor selectivity. Neuron 45, 539-552, 2005.
    • (2005) Neuron , vol.45 , pp. 539-552
    • Mayer, M.L.1
  • 61
    • 33645321641 scopus 로고    scopus 로고
    • Glutamate receptors at atomic resolution
    • MAYER ML, Glutamate receptors at atomic resolution. Nature 440, 456-462, 2006.
    • (2006) Nature , vol.440 , pp. 456-462
    • Mayer, M.L.1
  • 62
    • 0023492484 scopus 로고
    • Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones
    • MAYER ML, WESTBROOK GL, Permeation and block of N-methyl-D-aspartic acid receptor channels by divalent cations in mouse cultured central neurones. J Physiol 394, 501-527, 1987.
    • (1987) J Physiol , vol.394 , pp. 501-527
    • Mayer, M.L.1    Westbrook, G.L.2
  • 63
    • 0024521588 scopus 로고
    • Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine
    • MAYER ML, VYKLICKY L JR, CLEMENTS J, Regulation of NMDA receptor desensitization in mouse hippocampal neurons by glycine. Nature 338, 425-427, 1989.
    • (1989) Nature , vol.338 , pp. 425-427
    • Mayer, M.L.1    Vyklicky, L.2    Clements, J.R.J.3
  • 64
    • 2342462388 scopus 로고    scopus 로고
    • Structure and function of glutamate receptor ion channels
    • MAYER ML, ARMSTRONG N, Structure and function of glutamate receptor ion channels. Annu Rev Physiol 66, 161-181, 2004.
    • (2004) Annu Rev Physiol , vol.66 , pp. 161-181
    • Mayer, M.L.1    Armstrong, N.2
  • 66
    • 79961020657 scopus 로고    scopus 로고
    • Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines
    • MONY L, ZHU S, CARVALHO S, PAOLETTI P, Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines. Embo J 30, 3134-3146, 2011.
    • (2011) Embo J , vol.30 , pp. 3134-3146
    • Mony, L.1    Carvalho, Z.H.U.S.2    Paoletti, S.P.3
  • 69
    • 17144378207 scopus 로고    scopus 로고
    • Synthesis and pharmacology of N1-substituted piperazine-2 3-dicarboxylic acid derivatives acting as NMDA receptor antagonists
    • MORLEY RM, TSE HW, FENG B, MILLER JC, MONAGHAN DT, JANE DE, Synthesis and pharmacology of N1-substituted piperazine-2,3-dicarboxylic acid derivatives acting as NMDA receptor antagonists. J Med Chem 48, 2627-2637, 2005.
    • (2005) J Med Chem , vol.48 , pp. 2627-2637
    • Morley, R.M.1    Tse, H.W.2    Feng, B.3    Miller, J.C.4    Monaghan, D.T.5    Jane, D.E.6
  • 72
    • 33744475611 scopus 로고    scopus 로고
    • Extracellular level of GABA and Glu, in vivo microdialysis-HPLC measurements
    • NYITRAI G, KEKESI KA, JUHASZ G, Extracellular level of GABA and Glu, in vivo microdialysis-HPLC measurements. Curr Top Med Chem 6, 935-940, 2006.
    • (2006) Curr Top Med Chem , vol.6 , pp. 935-940
    • Nyitrai, G.1    Kekesi, K.A.2    Juhasz, G.3
  • 73
    • 84876545275 scopus 로고    scopus 로고
    • Contribution of the M1 transmembrane helix and pre-M1 region to positive allosteric modulation and gating of N-methyl-D-aspartate receptors
    • OGDEN KK, TRAYNELIS SF, Contribution of the M1 transmembrane helix and pre-M1 region to positive allosteric modulation and gating of N-methyl-D-aspartate receptors. Mol Pharmacol 83, 1045-1056, 2013.
    • (2013) Mol Pharmacol , vol.83 , pp. 1045-1056
    • Ogden, K.K.1    Traynelis, S.F.2
  • 74
    • 84859265035 scopus 로고    scopus 로고
    • GluN3 subunit-containing NMDA receptors, not just one-trick ponies
    • PACHERNEGG S, STRUTZ-SEEBOHM N, HOLLMANN M, GluN3 subunit-containing NMDA receptors, not just one-trick ponies. Trends Neurosci 35, 240-249, 2012.
    • (2012) Trends Neurosci , vol.35 , pp. 240-249
    • Pachernegg, S.1    Strutz-Seebohm, N.2    Hollmann, M.3
  • 76
    • 0031467726 scopus 로고    scopus 로고
    • Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids
    • PARK-CHUNG M, WU FS, PURDY RH, MALAYEV AA, GIBBS TT, FARB DH, Distinct sites for inverse modulation of N-methyl-D-aspartate receptors by sulfated steroids. Mol Pharmacol 52, 1113-1123, 1997.
    • (1997) Mol Pharmacol , vol.52 , pp. 1113-1123
    • Park-Chung, M.1    Wu, F.S.2    Purdy, R.H.3    Malayev, A.A.4    Gibbs, T.T.5    Farb, D.H.6
  • 77
    • 0025456905 scopus 로고
    • Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors
    • PATNEAU DK, MAYER ML, Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors. J Neurosci 10, 2385-2399, 1990.
    • (1990) J Neurosci , vol.10 , pp. 2385-2399
    • Patneau, D.K.1    Mayer, M.L.2
  • 78
    • 24944484111 scopus 로고    scopus 로고
    • 20-oxo-5beta-pregnan-3alpha-yl sulfate is a use-dependent NMDA receptor inhibitor
    • PETROVIC M, SEDLACEK M, HORAK M, CHODOUNSKA H, VYKLICKY L JR, 20-oxo-5beta-pregnan-3alpha-yl sulfate is a use-dependent NMDA receptor inhibitor. J Neurosci 25, 8439-8450, 2005.
    • (2005) J Neurosci , vol.25 , pp. 8439-8450
    • Petrovic, M.1    Sedlacek, M.2    Horak, M.3    Chodounska, H.4    Vyklicky, L.J.R.5
  • 79
    • 64449085156 scopus 로고    scopus 로고
    • Pregnenolone sulfate modulation of N-methyl-D-aspartate receptors is phosphorylation dependent
    • PETROVIC M, SEDLACEK M, CAIS O, HORAK M, CHODOUNSKA H, VYKLICKY L JR, Pregnenolone sulfate modulation of N-methyl-D-aspartate receptors is phosphorylation dependent. Neuroscience 160, 616-628, 2009.
    • (2009) Neuroscience , vol.160 , pp. 616-628
    • Petrovic, M.1    Sedlacek, M.2    Cais, O.3    Horak, M.4    Chodounska, H.5    Vyklicky, L.J.R.6
  • 80
    • 0038065481 scopus 로고    scopus 로고
    • Characterization of modes of release of amino acids in the ischemic/reperfused rat cerebral cortex
    • PHILLIS JW, O'REGAN MH, Characterization of modes of release of amino acids in the ischemic/reperfused rat cerebral cortex. Neurochem Int 43, 461-467, 2003.
    • (2003) Neurochem Int , vol.43 , pp. 461-467
    • Phillis, J.W.1    O'regan, M.H.2
  • 81
    • 0037407919 scopus 로고    scopus 로고
    • Modal gating of NMDA receptors and the shape of their synaptic response
    • POPESCU G, AUERBACH A, Modal gating of NMDA receptors and the shape of their synaptic response. Nat Neurosci 6, 476-483, 2003.
    • (2003) Nat Neurosci , vol.6 , pp. 476-483
    • Popescu, G.1    Auerbach, A.2
  • 82
    • 0037012062 scopus 로고    scopus 로고
    • Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating
    • SOBOLEVSKY AI, BECK C, WOLLMUTH LP, Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating. Neuron 33, 75-85, 2002.
    • (2002) Neuron , vol.33 , pp. 75-85
    • Sobolevsky, A.I.1    Beck, C.2    Wollmuth, L.P.3
  • 83
    • 34249809760 scopus 로고    scopus 로고
    • Subunit-specific contribution of pore-forming domains to NMDA receptor channel structure and gating
    • SOBOLEVSKY AI, PRODROMOU ML, YELSHANSKY MV, WOLLMUTH LP, Subunit-specific contribution of pore-forming domains to NMDA receptor channel structure and gating. J Gen Physiol 129, 509-525, 2007.
    • (2007) J Gen Physiol , vol.129 , pp. 509-525
    • Sobolevsky, A.I.1    Prodromou, M.L.2    Yelshansky, M.V.3    Wollmuth, L.P.4
  • 84
    • 72049124287 scopus 로고    scopus 로고
    • X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor
    • SOBOLEVSKY AI, ROSCONI MP, GOUAUX E, X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor. Nature 462, 745-756, 2009.
    • (2009) Nature , vol.462 , pp. 745-756
    • Sobolevsky, A.I.1    Rosconi, M.P.2    Gouaux, E.3
  • 85
    • 0026766877 scopus 로고
    • Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing
    • SUGIHARA H, MORIYOSHI K, ISHII T, MASU M, NAKANISHI S, Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing. Biochem Biophys Res Commun 185, 826-832, 1992.
    • (1992) Biochem Biophys Res Commun , vol.185 , pp. 826-832
    • Sugihara, H.1    Moriyoshi, K.2    Ishii, T.3    Masu, M.4    Nakanishi, S.5
  • 86
    • 0029021010 scopus 로고
    • Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines
    • TRAYNELIS SF, HARTLEY M, HEINEMANN SF, Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines. Science 268, 873-876, 1995.
    • (1995) Science , vol.268 , pp. 873-876
    • Traynelis, S.F.1    Hartley, M.2    Heinemann, S.F.3
  • 89
    • 84897644040 scopus 로고    scopus 로고
    • Human physiology, the mechanism of body function
    • New York
    • VANDER AJ, SHERMAN JH, LUCIANO DS, Human physiology, the mechanism of body function. McGraw-Hill, New York, 2001, pp 129, 184.
    • (2001) McGraw-Hill , vol.129 , pp. 184
    • Vander, A.J.1    Sherman, J.H.2    Luciano, D.S.3
  • 90
    • 0032006303 scopus 로고    scopus 로고
    • Glycine-independent NMDA receptor desensitization, localization of structural determinants
    • VILLARROEL A, REGALADO MP, LERMA J, Glycine-independent NMDA receptor desensitization, localization of structural determinants. Neuron 20, 329-339, 1998.
    • (1998) Neuron , vol.20 , pp. 329-339
    • Villarroel, A.1    Regalado, M.P.2    Lerma, J.3
  • 91
    • 0027452412 scopus 로고
    • Calcium-mediated modulation of N-methyl-D-aspartate (NMDA) responses in cultured rat hippocampal neurones
    • VYKLICKY L JR, Calcium-mediated modulation of N-methyl-D-aspartate (NMDA) responses in cultured rat hippocampal neurones. J Physiol 470, 575-600, 1993.
    • (1993) J Physiol , vol.470 , pp. 575-600
    • Vyklicky, L.J.R.1
  • 93
    • 0027525324 scopus 로고
    • Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor, selectivity and mechanisms at recombinant heteromeric receptors
    • WILLIAMS K, Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor, selectivity and mechanisms at recombinant heteromeric receptors. Mol Pharmacol 44, 851-859, 1993.
    • (1993) Mol Pharmacol , vol.44 , pp. 851-859
    • Williams, K.1
  • 94
    • 0025063670 scopus 로고
    • Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor
    • WILLIAMS K, DAWSON VL, ROMANO C, DICHTER MA, MOLINOFF PB, Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor. Neuron 5, 199-208, 1990.
    • (1990) Neuron , vol.5 , pp. 199-208
    • Williams, K.1    Dawson, V.L.2    Romano, C.3    Dichter, M.A.4    Molinoff, P.B.5
  • 96
    • 0025995802 scopus 로고
    • Pregnenolone sulfate, a positive allosteric modulator at the N-methyl-D-aspartate receptor
    • WU FS, GIBBS TT, FARB DH, Pregnenolone sulfate, a positive allosteric modulator at the N-methyl-D-aspartate receptor. Mol Pharmacol 40, 333-336, 1991.
    • (1991) Mol Pharmacol , vol.40 , pp. 333-336
    • Wu, F.S.1    Gibbs, T.T.2    Farb, D.H.3
  • 97
    • 77955855654 scopus 로고    scopus 로고
    • Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses
    • XIA P, CHEN HS, ZHANG D, LIPTON SA, Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses. J Neurosci 30, 11246-11250, 2010.
    • (2010) J Neurosci , vol.30 , pp. 11246-11250
    • Chen, H.S.1    Xia, P.2    Zhang, D.3    Lipton, S.A.4
  • 98
    • 0029073172 scopus 로고
    • Alternatively spliced isoforms of the NMDARI receptor subunit
    • ZUKIN RS, BENNETT MV, Alternatively spliced isoforms of the NMDARI receptor subunit. Trends Neurosci 18, 306-313, 1995.
    • (1995) Trends Neurosci , vol.18 , pp. 306-313
    • Zukin, R.S.1    Bennett, M.V.2
  • 99
    • 0030800468 scopus 로고    scopus 로고
    • Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene
    • ZUO J, DE JAGER PL, TAKAHASHI KA, JIANG W, LINDEN DJ, HEINTZ N, Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene. Nature 388, 769-773, 1997.
    • (1997) Nature , vol.388 , pp. 769-773
    • Zuo, J.1    De Jager, P.L.2    Takahashi, K.A.3    Jiang, W.4    Linden, D.J.5    Heintz, N.6


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