20-Oxo-5β-pregnan-3α:-yl sulfate is a use-dependent NMDA receptor inhibitor

Journal of Neuroscience

Volumn 25, Issue 37, 2005, Pages 8439-8450

  Petrovic, Milos ^a   Sedlacek, Miloslav ^a   Horak, Martin ^a   Chodounska, Hana ^b   Vyklický Jr , Ladislav ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

Author keywords

Culture; Inhibition; Neurosteroids; NMDA receptor; Patch clamp recording; Recombinant receptors

Indexed keywords

20 OXO 5BETA PREGNAN 3ALPHA YL SULFATE; GLUTAMIC ACID; GLYCINE; ION CHANNEL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; NEUROSTEROID; UNCLASSIFIED DRUG; 20-OXO-5BETA-PREGNAN-3ALPHA-YL SULFATE; PREGNANE DERIVATIVE;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CENTRAL NERVOUS SYSTEM; COMPLEX FORMATION; EXCITATORY POSTSYNAPTIC POTENTIAL; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; NERVE CELL CULTURE; NERVE CELL PLASTICITY; NERVE DEGENERATION; NERVE EXCITABILITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; SYNAPTIC TRANSMISSION; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CELL LINE; CELL MEMBRANE POTENTIAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; HIPPOCAMPUS; IN VITRO STUDY; NEOCORTEX; NEWBORN; PHYSIOLOGY;

ANIMALS; ANIMALS, NEWBORN; CELL LINE; CELLS, CULTURED; HIPPOCAMPUS; HUMANS; MEMBRANE POTENTIALS; MODELS, NEUROLOGICAL; NEOCORTEX; PATCH-CLAMP TECHNIQUES; PREGNANES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; TRANSFECTION;

EID: 24944484111     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1407-05.2005     Document Type: Article

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