-
1
-
-
0015319592
-
The biologic clock: The mitochondria?
-
Harman, D. The biologic clock: the mitochondria? J. Am. Geriatr. Soc. 20, 145-147 (1972).
-
(1972)
J. Am. Geriatr. Soc.
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
2
-
-
47549096022
-
Superoxide flashes in single mitochondria
-
Wang, W. et al. Superoxide flashes in single mitochondria. Cell 134, 279-290 (2008).
-
(2008)
Cell
, vol.134
, pp. 279-290
-
-
Wang, W.1
-
3
-
-
80052465160
-
Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals
-
Fang, H. et al. Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals. Cell Res. 21, 1295-1304 (2011).
-
(2011)
Cell Res.
, vol.21
, pp. 1295-1304
-
-
Fang, H.1
-
5
-
-
0036194529
-
Mitochondria as a pharmacological target
-
Szewczyk, A. & Wojtczak, L. Mitochondria as a pharmacological target. Pharmacol. Rev. 54, 101-127 (2002).
-
(2002)
Pharmacol. Rev.
, vol.54
, pp. 101-127
-
-
Szewczyk, A.1
Wojtczak, L.2
-
6
-
-
70349515574
-
Is theremore to aging than mitochondrialDNA and reactive oxygen species?
-
Alexeyev, M. F. Is theremore to aging than mitochondrialDNA and reactive oxygen species? FEBS J. 276, 5768-5787 (2009).
-
(2009)
FEBS J.
, vol.276
, pp. 5768-5787
-
-
Alexeyev, M.F.1
-
7
-
-
67349229199
-
Celegans longevity pathways converge to decrease mitochondrialmembrane potential
-
Lemire, B. D., Behrendt, M., DeCorby, A. & Gaskova, D. Celegans longevity pathways converge to decrease mitochondrialmembrane potential. Mech. Ageing Dev. 130, 461-465 (2009).
-
(2009)
Mech. Ageing Dev.
, vol.130
, pp. 461-465
-
-
Lemire, B.D.1
Behrendt, M.2
Decorby, A.3
Gaskova, D.4
-
8
-
-
77950200010
-
The genetics of ageing
-
Kenyon, C. J. The genetics of ageing. Nature 464, 504-512 (2010).
-
(2010)
Nature
, vol.464
, pp. 504-512
-
-
Kenyon, C.J.1
-
9
-
-
30544443562
-
A genetically encoded photosensitizer
-
Bulina, M. E. et al. A genetically encoded photosensitizer. Nature Biotechnol. 24, 95-99 (2006).
-
(2006)
Nature Biotechnol.
, vol.24
, pp. 95-99
-
-
Bulina, M.E.1
-
10
-
-
0027771804
-
AC.elegansmutant that lives twice as longas wild type
-
Kenyon, C. et al. AC.elegansmutant that lives twice as longas wild type. Nature366, 461-464 (1993).
-
(1993)
Nature
, vol.366
, pp. 461-464
-
-
Kenyon, C.1
-
11
-
-
78650455712
-
A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans
-
Yang, W. & Hekimi, S. A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biol. 8, e1000556 (2010).
-
(2010)
PLoS Biol
, vol.8
-
-
Yang, W.1
Hekimi, S.2
-
12
-
-
79954571967
-
Amyloid-binding compoundsmaintain protein homeostasis during ageing and extend lifespan
-
Alavez, S. et al.Amyloid-binding compoundsmaintain protein homeostasis during ageing and extend lifespan. Nature 472, 226-229 (2011).
-
(2011)
Nature
, vol.472
, pp. 226-229
-
-
Alavez, S.1
-
13
-
-
77952908744
-
A neuromedin U receptor acts with the sensory system to modulate food type-dependent effects on C.elegans lifespan
-
Maier, W., Adilov, B., Regenass, M. & Alcedo, J. A neuromedin U receptor acts with the sensory system to modulate food type-dependent effects on C.elegans lifespan. PLoS Biol. 8, e1000376 (2010).
-
(2010)
PLoS Biol.
, vol.8
-
-
Maier, W.1
Adilov, B.2
Regenass, M.3
Alcedo, J.4
-
14
-
-
78650627214
-
DDS, 4,49-diaminodiphenylsulfone, extends organismic lifespan
-
Cho, S. C. et al. DDS, 4,49-diaminodiphenylsulfone, extends organismic lifespan. Proc. Natl Acad. Sci. USA 107, 19326-19331 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 19326-19331
-
-
Cho, S.C.1
-
15
-
-
80053385974
-
Curcumin-mediated lifespan extension in Caenorhabditis elegans
-
Liao, V. H. et al. Curcumin-mediated lifespan extension in Caenorhabditis elegans. Mech. Ageing Dev. 132, 480-487 (2011).
-
(2011)
Mech. Ageing Dev.
, vol.132
, pp. 480-487
-
-
Liao, V.H.1
-
16
-
-
84860461929
-
TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO
-
Robida-Stubbs, S. et al. TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO. Cell Metab. 15, 713-724 (2012).
-
(2012)
Cell Metab.
, vol.15
, pp. 713-724
-
-
Robida-Stubbs, S.1
-
17
-
-
79960752604
-
High glucose diets shorten lifespan of Caenorhabditis elegans via ectopic apoptosis induction
-
Choi, S. S. High glucose diets shorten lifespan of Caenorhabditis elegans via ectopic apoptosis induction. Nutr. Res. Pract. 5, 214-218 (2011).
-
(2011)
Nutr. Res. Pract.
, vol.5
, pp. 214-218
-
-
Choi, S.S.1
-
18
-
-
33751542902
-
Hormesis and aging in Caenorhabditis elegans
-
Cypser, J. R., Tedesco, P. & Johnson, T. E. Hormesis and aging in Caenorhabditis elegans. Exp. Gerontol. 41, 935-939 (2006).
-
(2006)
Exp. Gerontol.
, vol.41
, pp. 935-939
-
-
Cypser, J.R.1
Tedesco, P.2
Johnson, T.E.3
-
19
-
-
78049437929
-
Trehalose extends longevity in the nematode Caenorhabditis elegans
-
Honda, Y., Tanaka, M. & Honda, S. Trehalose extends longevity in the nematode Caenorhabditis elegans. Aging Cell 9, 558-569 (2010).
-
(2010)
Aging Cell
, vol.9
, pp. 558-569
-
-
Honda, Y.1
Tanaka, M.2
Honda, S.3
-
20
-
-
34249888736
-
PHA-4/Foxa mediates diet-restriction-induced longevity of C elegans
-
Panowski, S. H. et al. PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegans. Nature 447, 550-555 (2007).
-
(2007)
Nature
, vol.447
, pp. 550-555
-
-
Panowski, S.H.1
-
21
-
-
84865108931
-
Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan
-
Steinbaugh, M. J., Sun, L. Y., Bartke, A. & Miller, R. A. Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan. Am. J. Physiol. Endocrinol. Metab. 303, E488-E495 (2012).
-
(2012)
Am. J. Physiol. Endocrinol. Metab.
, vol.303
-
-
Steinbaugh, M.J.1
Sun, L.Y.2
Bartke, A.3
Miller, R.A.4
-
22
-
-
80053446656
-
MicroRNA predictors of longevity in Caenorhabditis elegans
-
Pincus, Z., Smith-Vikos, T. & Slack, F. J. MicroRNA predictors of longevity in Caenorhabditis elegans. PLoS Genet. 7, e1002306 (2011).
-
(2011)
PLoS Genet.
, vol.7
-
-
Pincus, Z.1
Smith-Vikos, T.2
Slack, F.J.3
-
23
-
-
84893738283
-
Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of Ab1-42 on neural progenitor cell proliferation
-
18 November 2013
-
Hou, Y. et al. Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of Ab1-42 on neural progenitor cell proliferation. Neurobiol. Aging http://dx.doi.org/10.1016/j. neurobiolaging.2013. 11.002 (18 November 2013).
-
Neurobiol. Aging
-
-
Hou, Y.1
-
24
-
-
0037167855
-
Stochastic and genetic factors influence tissue-specific decline in ageing C elegans
-
Herndon, L. A. et al. Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 419, 808-814 (2002).
-
(2002)
Nature
, vol.419
, pp. 808-814
-
-
Herndon, L.A.1
-
25
-
-
2542643174
-
Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans
-
Huang, C., Xiong, C. & Kornfeld, K. Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 101, 8084-8089 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 8084-8089
-
-
Huang, C.1
Xiong, C.2
Kornfeld, K.3
-
26
-
-
67650483333
-
Identification bymachine vision of the rate of motor activity decline as a lifespan predictor in C.elegans
-
Hsu, A. L.,Feng, Z.,Hsieh, M. Y.&Xu, X. Z. Identification bymachine vision of the rate of motor activity decline as a lifespan predictor in C. elegans. Neurobiol. Aging 30, 1498-1503 (2009).
-
(2009)
Neurobiol. Aging
, vol.30
, pp. 1498-1503
-
-
Hsu, A.L.1
Fengm, Z.2
Hsieh, M.Y.3
Xu, X.Z.4
-
27
-
-
79955622698
-
Variable pathogenicity determines individual lifespan in Caenorhabditis elegans
-
Sanchez-Blanco, A. & Kim, S. K. Variable pathogenicity determines individual lifespan in Caenorhabditis elegans. PLoS Genet. 7, e1002047 (2011).
-
(2011)
PLoS Genet.
, vol.7
-
-
Sanchez-Blanco, A.1
Kim, S.K.2
-
28
-
-
0042092531
-
Genes that act downstreamof DAF-16 to influence the lifespan of Caenorhabditis elegans
-
Murphy, C. T. et al. Genes that act downstreamof DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424, 277-283 (2003).
-
(2003)
Nature
, vol.424
, pp. 277-283
-
-
Murphy, C.T.1
-
29
-
-
34547810054
-
Quantitative mass spectrometry identifies insulin signaling targets in C elegans
-
Dong, M. Q. et al. Quantitative mass spectrometry identifies insulin signaling targets in C. elegans. Science 317, 660-663 (2007).
-
(2007)
Science
, vol.317
, pp. 660-663
-
-
Dong, M.Q.1
-
30
-
-
0348150715
-
Architecture of succinate dehydrogenase and reactive oxygen species generation
-
Yankovskaya, V. et al. Architecture of succinate dehydrogenase and reactive oxygen species generation. Science 299, 700-704 (2003).
-
(2003)
Science
, vol.299
, pp. 700-704
-
-
Yankovskaya, V.1
-
31
-
-
0037448540
-
Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
-
Kamath, R. S. et al. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421, 231-237 (2003).
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
-
32
-
-
84860390185
-
Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage
-
Cabreiro, F. et al. Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage. Free Radic. Biol. Med. 51, 1575-1582 (2011).
-
(2011)
Free Radic. Biol. Med.
, vol.51
, pp. 1575-1582
-
-
Cabreiro, F.1
-
33
-
-
70350217759
-
Proteomic analysis of mitochondria from Caenorhabditis elegans
-
Li, J. et al. Proteomic analysis of mitochondria from Caenorhabditis elegans. Proteomics 9, 4539-4553 (2009).
-
(2009)
Proteomics
, vol.9
, pp. 4539-4553
-
-
Li, J.1
-
34
-
-
0035231595
-
Assaying mitochondrial respiratory complex activity in mitochondria isolated fromhuman cells and tissues
-
Birch-Machin, M. A. & Turnbull, D. M. Assaying mitochondrial respiratory complex activity in mitochondria isolated fromhuman cells and tissues.Methods Cell Biol. 65, 97-117 (2001).
-
(2001)
Methods Cell Biol.
, vol.65
, pp. 97-117
-
-
Birch-Machin, M.A.1
Turnbull, D.M.2
|