Downregulation of the Wnt/β-catenin signaling pathway is involved in manganese-induced neurotoxicity in rat striatum and PC12 cells

Journal of Neuroscience Research

Volumn 92, Issue 6, 2014, Pages 783-794

  Jiang, Junkang ^a   Shi, Shangshi ^a   Zhou, Qiang ^a   Ma, Xia ^a   Nie, Xiaoke ^a   Yang, Lingling ^a   Han, Jingling ^a   Xu, Guangfei ^a   Wan, Chunhua ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Mn; Neuronal apoptosis; PC12 cells; Striatum; Wnt catenin signaling

Indexed keywords

BETA CATENIN; CASPASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM CHLORIDE; MANGANESE; NERVE GROWTH FACTOR; SURVIVIN; WNT PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL COUNTING; CELL VIABILITY; CONTROLLED STUDY; CORPUS STRIATUM; CYTOTOXICITY; DOWN REGULATION; ENZYME ACTIVITY; HOMEOSTASIS; MALE; NERVE CELL; NEUROTOXICITY; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; WNT SIGNALING PATHWAY; ANIMAL; CHEMICALLY INDUCED; DRUG EFFECTS; IMMUNOHISTOCHEMISTRY; METABOLISM; NERVE DEGENERATION; NICK END LABELING; PATHOLOGY; PC12 CELL LINE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TOXICITY; TOXICITY AND INTOXICATION; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CORPUS STRIATUM; DOWN-REGULATION; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; MALE; MANGANESE; NERVE DEGENERATION; NEURONS; NEUROTOXICITY SYNDROMES; PC12 CELLS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; WNT SIGNALING PATHWAY;

EID: 84897571983     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.23352     Document Type: Article

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