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Volumn 334-335, Issue , 2004, Pages 409-416

Manganese exposure and induced oxidative stress in the rat brain

Author keywords

Brain; Glutamine synthetase; Glutathione; Manganese; Metallothionein; MMT; Neurotoxicity

Indexed keywords

ANTIOXIDANTS; BIOMARKERS; BRAIN; MANGANESE; METABOLISM; NEUROLOGY; OXIDATION; RESPIRATORY SYSTEM; STRESS ANALYSIS; TOXICITY;

EID: 7044286177     PISSN: 00489697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.scitotenv.2004.04.044     Document Type: Review
Times cited : (143)

References (66)
  • 2
    • 0036523088 scopus 로고    scopus 로고
    • Caspase-3-dependent proteolytic cleavage of protein kinase C delta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl
    • Anantharam V., Kitazawa M., Wagner J., Kaul S., Kanthasamy A.G. Caspase-3-dependent proteolytic cleavage of protein kinase C delta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl. J. Neurosci. 22:2002;1738-1751
    • (2002) J. Neurosci. , vol.22 , pp. 1738-1751
    • Anantharam, V.1    Kitazawa, M.2    Wagner, J.3    Kaul, S.4    Kanthasamy, A.G.5
  • 3
    • 0020662578 scopus 로고
    • Transport and direct utilization of gamma-glutamylcyst(e)ine for glutathione synthesis
    • Anderson M.E., Meister A. Transport and direct utilization of gamma-glutamylcyst(e)ine for glutathione synthesis. Proc. Natl. Acad. Sci. 80:1983;707-711
    • (1983) Proc. Natl. Acad. Sci. , vol.80 , pp. 707-711
    • Anderson, M.E.1    Meister, A.2
  • 4
    • 0025154985 scopus 로고
    • Regulation of metallothioneins gene expression
    • Andrews G.K. Regulation of metallothioneins gene expression. Prog. Food Nutr. Sci. 14:1990;193-258
    • (1990) Prog. Food Nutr. Sci. , vol.14 , pp. 193-258
    • Andrews, G.K.1
  • 5
    • 0023261328 scopus 로고
    • Manganese poisoning and the attack of trivalent manganese upon catecholamines
    • Archibald F.S., Tyree C. Manganese poisoning and the attack of trivalent manganese upon catecholamines. Arch. Biochem. Biophys. 256:1987;638-650
    • (1987) Arch. Biochem. Biophys. , vol.256 , pp. 638-650
    • Archibald, F.S.1    Tyree, C.2
  • 7
    • 0026536560 scopus 로고
    • Manganese (Mn) uptake and efflux in cultured rat astrocytes
    • Aschner M., Gannon M., Kimelberg H.K. Manganese (Mn) uptake and efflux in cultured rat astrocytes. J. Neurochem. 58:1992;730-735
    • (1992) J. Neurochem. , vol.58 , pp. 730-735
    • Aschner, M.1    Gannon, M.2    Kimelberg, H.K.3
  • 8
    • 0023260036 scopus 로고
    • Homeostatic control of manganese excretion in the neonatal rat
    • Ballatori N., Miles E., Clarkson T.W. Homeostatic control of manganese excretion in the neonatal rat. Am. J. Physiol. 252:1987;R842-R847
    • (1987) Am. J. Physiol. , vol.252
    • Ballatori, N.1    Miles, E.2    Clarkson, T.W.3
  • 9
    • 0025944389 scopus 로고
    • Increase in metallothionein produced by chemicals that induced oxidative stress
    • Bauman J.W., Liu J., Liu Y.P., Klaassen C.D. Increase in metallothionein produced by chemicals that induced oxidative stress. Toxicol. Appl. Pharmacol. 110:1991;347-354
    • (1991) Toxicol. Appl. Pharmacol. , vol.110 , pp. 347-354
    • Bauman, J.W.1    Liu, J.2    Liu, Y.P.3    Klaassen, C.D.4
  • 11
    • 84982337275 scopus 로고
    • Amino acid and protein metabolism: VI. Cerebral compartments of glutamic acid metabolism
    • Berl S., Lajtha A., Waelsch A. Amino acid and protein metabolism: VI. Cerebral compartments of glutamic acid metabolism. J. Neurochem. 7:1961;186-197
    • (1961) J. Neurochem. , vol.7 , pp. 186-197
    • Berl, S.1    Lajtha, A.2    Waelsch, A.3
  • 12
    • 0031031845 scopus 로고    scopus 로고
    • Platelet mitochondrial respiratory chain function in Parkinson's disease
    • Blake C.I., Spitz E., Leehey M., Hoffer B.J., Boyson S.J. Platelet mitochondrial respiratory chain function in Parkinson's disease. Mov. Disord. 12:1997;3-8
    • (1997) Mov. Disord. , vol.12 , pp. 3-8
    • Blake, C.I.1    Spitz, E.2    Leehey, M.3    Hoffer, B.J.4    Boyson, S.J.5
  • 13
    • 0033042992 scopus 로고    scopus 로고
    • Manganese-induced developmental neurotoxicity in the CD rat: Is oxidative damage a mechanism of action?
    • Brenneman K.A., Cattley R.C., Ali S.F., Dorman D.C. Manganese-induced developmental neurotoxicity in the CD rat: is oxidative damage a mechanism of action? Neurotoxicology. 20:1999;477-487
    • (1999) Neurotoxicology , vol.20 , pp. 477-487
    • Brenneman, K.A.1    Cattley, R.C.2    Ali, S.F.3    Dorman, D.C.4
  • 14
    • 0028023508 scopus 로고
    • Manganism and idiopathic Parkinsonism: Similarities and difference
    • Calne D.B., Chu N.S., Huang C.C., Lu C.S., Olanow W. Manganism and idiopathic Parkinsonism: similarities and difference. Neurology. 44:1994;1583-1586
    • (1994) Neurology , vol.44 , pp. 1583-1586
    • Calne, D.B.1    Chu, N.S.2    Huang, C.C.3    Lu, C.S.4    Olanow, W.5
  • 15
    • 0035448662 scopus 로고    scopus 로고
    • Differential cytotoxicity of Mn(II) and Mn(III): Special reference to mitochondrial [Fe-S] containing enzymes
    • Chen J.Y., Tsao G.C., Zhao Q., Zheng W. Differential cytotoxicity of Mn(II) and Mn(III): special reference to mitochondrial [Fe-S] containing enzymes. Toxicol. Appl. Pharmacol. 175:2001;160-168
    • (2001) Toxicol. Appl. Pharmacol. , vol.175 , pp. 160-168
    • Chen, J.Y.1    Tsao, G.C.2    Zhao, Q.3    Zheng, W.4
  • 16
    • 0024446303 scopus 로고
    • Deprenyl suppresses the oxidant stress associated with dopamine turnover
    • Cohen G., Spina M.B. Deprenyl suppresses the oxidant stress associated with dopamine turnover. Ann. Neurol. 26:1989;689-690
    • (1989) Ann. Neurol. , vol.26 , pp. 689-690
    • Cohen, G.1    Spina, M.B.2
  • 17
    • 0031257743 scopus 로고    scopus 로고
    • Glutathione deficiency potentiates manganese toxicity in rat striatum and brainstem and in PC12 cells
    • DeSole M.S., Esposito G., Migheli R., Sircana S., Delogu M.R., Fresu L., et al. Glutathione deficiency potentiates manganese toxicity in rat striatum and brainstem and in PC12 cells. Pharmacol. Res. 36:1997;285-292
    • (1997) Pharmacol. Res. , vol.36 , pp. 285-292
    • Desole, M.S.1    Esposito, G.2    Migheli, R.3    Sircana, S.4    Delogu, M.R.5    Fresu, L.6
  • 19
    • 0034009576 scopus 로고    scopus 로고
    • Neurotoxicity of manganese chloride in neonatal and adult CD rats following subchronic (21-day) high-dose oral exposure
    • Dorman D.C., Struve M.F., Vitarella D., Byerly F.L., Goetz J., Miller R. Neurotoxicity of manganese chloride in neonatal and adult CD rats following subchronic (21-day) high-dose oral exposure. J. Appl. Toxicol. 20:2000;179-187
    • (2000) J. Appl. Toxicol. , vol.20 , pp. 179-187
    • Dorman, D.C.1    Struve, M.F.2    Vitarella, D.3    Byerly, F.L.4    Goetz, J.5    Miller, R.6
  • 20
    • 0035862914 scopus 로고    scopus 로고
    • Influence of particle solubility on the delivery of inhaled manganese to the rat brain: Manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure
    • Dorman D.C., Struve M.F., James R.A., Marshall M.W., Parkinson C.U., Wong B.A. Influence of particle solubility on the delivery of inhaled manganese to the rat brain: manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure. Toxicol. Appl. Pharmacol. 170:2001;79-87
    • (2001) Toxicol. Appl. Pharmacol. , vol.170 , pp. 79-87
    • Dorman, D.C.1    Struve, M.F.2    James, R.A.3    Marshall, M.W.4    Parkinson, C.U.5    Wong, B.A.6
  • 21
    • 0022634773 scopus 로고
    • Pulmonary clearance of soluble and insoluble forms of manganese
    • Drown D.B., Oberg S.G., Sharma S.P. Pulmonary clearance of soluble and insoluble forms of manganese. J. Toxicol. Environ. Health. 17:1986;201-212
    • (1986) J. Toxicol. Environ. Health , vol.17 , pp. 201-212
    • Drown, D.B.1    Oberg, S.G.2    Sharma, S.P.3
  • 23
    • 0021910276 scopus 로고
    • Blood manganese levels in children with convulsive disorder
    • Dupont C.L., Tanaka Y. Blood manganese levels in children with convulsive disorder. Biochem. Med. 33:1985;246-255
    • (1985) Biochem. Med. , vol.33 , pp. 246-255
    • Dupont, C.L.1    Tanaka, Y.2
  • 24
    • 0036778081 scopus 로고    scopus 로고
    • Manganese causes differential regulation of glutamate transporter, taurine transporter and metallothionein in cultured rat astrocytes
    • Erikson K.M., Aschner M. Manganese causes differential regulation of glutamate transporter, taurine transporter and metallothionein in cultured rat astrocytes. Neurotoxicology. 23:2002;595-602
    • (2002) Neurotoxicology , vol.23 , pp. 595-602
    • Erikson, K.M.1    Aschner, M.2
  • 25
    • 0036746169 scopus 로고    scopus 로고
    • Glutamate/aspartate (GLAST), taurine transporter, and metallothionein mRNA levels are differentially altered in astrocytes exposed to manganese chloride, manganese phosphate, and manganese sulfate
    • Erikson K.M., Suber R.L., Aschner M. Glutamate/aspartate (GLAST), taurine transporter, and metallothionein mRNA levels are differentially altered in astrocytes exposed to manganese chloride, manganese phosphate, and manganese sulfate. Neurotoxicology. 23:2002;281-288
    • (2002) Neurotoxicology , vol.23 , pp. 281-288
    • Erikson, K.M.1    Suber, R.L.2    Aschner, M.3
  • 26
    • 0026484388 scopus 로고
    • The oxidant stress hypothesis in Parkinson's disease: Evidence supporting it
    • Fahn S., Cohen G. The oxidant stress hypothesis in Parkinson's disease: evidence supporting it. Ann. Neurol. 32:1992;804-812
    • (1992) Ann. Neurol. , vol.32 , pp. 804-812
    • Fahn, S.1    Cohen, G.2
  • 27
    • 0028973338 scopus 로고
    • Vulnerability of mitochondrial complex I in PC12 cells exposed to manganese
    • Galvani P., Fumagalli P., Santagostino A. Vulnerability of mitochondrial complex I in PC12 cells exposed to manganese. Eur. J. Pharmacol. 293:1995;377-383
    • (1995) Eur. J. Pharmacol. , vol.293 , pp. 377-383
    • Galvani, P.1    Fumagalli, P.2    Santagostino, A.3
  • 28
    • 0033002854 scopus 로고    scopus 로고
    • Manganese and calcium transport in mitochondria: Implications for manganese toxicity
    • Gavin C.E., Gunter K.K., Gunter T.E. Manganese and calcium transport in mitochondria: implications for manganese toxicity. Neurotoxicology. 20:1999;445-453
    • (1999) Neurotoxicology , vol.20 , pp. 445-453
    • Gavin, C.E.1    Gunter, K.K.2    Gunter, T.E.3
  • 29
    • 0035884869 scopus 로고    scopus 로고
    • Modulation of oxidative events by multivalent manganese complexes in brain tissue
    • HaMai D., Campbell A., Bondy S.C. Modulation of oxidative events by multivalent manganese complexes in brain tissue. Free Radic. Biol. Med. 31:2001;763-768
    • (2001) Free Radic. Biol. Med. , vol.31 , pp. 763-768
    • Hamai, D.1    Campbell, A.2    Bondy, S.C.3
  • 30
  • 31
    • 0030831158 scopus 로고    scopus 로고
    • Manganese decreases glutamate uptake in cultured astrocytes
    • Hazell A.S., Norenberg M.D. Manganese decreases glutamate uptake in cultured astrocytes. Neurochem. Res. 22:1997;1443-1447
    • (1997) Neurochem. Res. , vol.22 , pp. 1443-1447
    • Hazell, A.S.1    Norenberg, M.D.2
  • 32
    • 0018670663 scopus 로고
    • Functional interactions between neurons and astrocytes I. Turnover and metabolism of putative amino acid transmitters
    • Hertz L. Functional interactions between neurons and astrocytes I. Turnover and metabolism of putative amino acid transmitters. Prog. Neurobiol. 13:1979;277-323
    • (1979) Prog. Neurobiol. , vol.13 , pp. 277-323
    • Hertz, L.1
  • 33
    • 0032997529 scopus 로고    scopus 로고
    • Central nervous system toxicity of manganese: II. Cocaine or reserpine inhibits manganese concentration in the rat brain
    • Ingersoll R.T., Montgomery E.B., Aposhian H.V. Central nervous system toxicity of manganese: II. Cocaine or reserpine inhibits manganese concentration in the rat brain. Neurotoxicology. 20:1999;467-476
    • (1999) Neurotoxicology , vol.20 , pp. 467-476
    • Ingersoll, R.T.1    Montgomery, E.B.2    Aposhian, H.V.3
  • 34
    • 0026078083 scopus 로고
    • Bacterial endotoxin-induced expression of metallothionein genes in rat brain, as revealed by in situ hybridization
    • Itano Y., Noji S., Koyama E., Taniguchi S., Taga N., Takahashi T., et al. Bacterial endotoxin-induced expression of metallothionein genes in rat brain, as revealed by in situ hybridization. Neurosci. Lett. 124:1991;13-16
    • (1991) Neurosci. Lett. , vol.124 , pp. 13-16
    • Itano, Y.1    Noji, S.2    Koyama, E.3    Taniguchi, S.4    Taga, N.5    Takahashi, T.6
  • 35
    • 0022651524 scopus 로고
    • The effect of age on manganese uptake and retention from milk and infant formulas in rats
    • Keen C.L., Bell J.G., Lonnerdal B. The effect of age on manganese uptake and retention from milk and infant formulas in rats. J. Nutr. 116:1986;395-402
    • (1986) J. Nutr. , vol.116 , pp. 395-402
    • Keen, C.L.1    Bell, J.G.2    Lonnerdal, B.3
  • 36
    • 0027380609 scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: Putative mediators of NMDA-induced cell death in cerebellar granule cells
    • Lafon-Cazal M., Culcasi M., Gaven F., Pietri S., Bockaert J. Nitric oxide, superoxide, and peroxynitrite: putative mediators of NMDA-induced cell death in cerebellar granule cells. Neuropharmacology. 32:1993;1259-1266
    • (1993) Neuropharmacology , vol.32 , pp. 1259-1266
    • Lafon-Cazal, M.1    Culcasi, M.2    Gaven, F.3    Pietri, S.4    Bockaert, J.5
  • 38
    • 0033001642 scopus 로고    scopus 로고
    • Environmental effects and exposures to manganese from use of methylcyclopentadienyl manganese tricarbonyl (MMT) in gasoline
    • Lynam D.R., Roos J.W., Pfeifer G.D., Fort B.F., Pullin T.G. Environmental effects and exposures to manganese from use of methylcyclopentadienyl manganese tricarbonyl (MMT) in gasoline. Neurotoxicology. 20:1999;145-150
    • (1999) Neurotoxicology , vol.20 , pp. 145-150
    • Lynam, D.R.1    Roos, J.W.2    Pfeifer, G.D.3    Fort, B.F.4    Pullin, T.G.5
  • 39
    • 0017579832 scopus 로고
    • Glutamine synthetase: Glial localization in brain
    • Martinez-Hernandez A., Bell K.P., Norenberg M.D. Glutamine synthetase: glial localization in brain. Science. 195:1977;1356-1358
    • (1977) Science , vol.195 , pp. 1356-1358
    • Martinez-Hernandez, A.1    Bell, K.P.2    Norenberg, M.D.3
  • 40
    • 0024264526 scopus 로고
    • Glutathione metabolism and its selective modification
    • Meister A. Glutathione metabolism and its selective modification. J. Biol. Chem. 263:1988;17205-17208
    • (1988) J. Biol. Chem. , vol.263 , pp. 17205-17208
    • Meister, A.1
  • 41
    • 0026343403 scopus 로고
    • Glutathione deficiency produced by inhibition of its synthesis, and reversal; Applications in research and therapy
    • Meister A. Glutathione deficiency produced by inhibition of its synthesis, and reversal; applications in research and therapy. Pharmacol. Ther. 51:1991;155-194
    • (1991) Pharmacol. Ther. , vol.51 , pp. 155-194
    • Meister, A.1
  • 42
    • 0033679154 scopus 로고    scopus 로고
    • Glutamate and catabolites of high energy phosphates in the striatum and brainstem of young and aged rats subchronically exposed to manganese
    • Miele M., Serra P.A., Esposito G., Delogu M.R., Migheli R., Rocchitta G., et al. Glutamate and catabolites of high energy phosphates in the striatum and brainstem of young and aged rats subchronically exposed to manganese. Aging. 12:2000;393-397
    • (2000) Aging , vol.12 , pp. 393-397
    • Miele, M.1    Serra, P.A.2    Esposito, G.3    Delogu, M.R.4    Migheli, R.5    Rocchitta, G.6
  • 43
    • 0016723679 scopus 로고
    • Control of tissue manganese: Initial absence and sudden emergence of excretion in the neonatal mouse
    • Miller S.T., Cotzias G.C., Evert H.A. Control of tissue manganese: initial absence and sudden emergence of excretion in the neonatal mouse. Am. J. Physiol. 229:1975;1080-1084
    • (1975) Am. J. Physiol. , vol.229 , pp. 1080-1084
    • Miller, S.T.1    Cotzias, G.C.2    Evert, H.A.3
  • 44
    • 0035830737 scopus 로고    scopus 로고
    • Striatal manganese accumulation induces changes in dopamine metabolism in the cirrhotic rat
    • Montes S., Alcaraz-Zubeldia M., Muriel P., Rios C. Striatal manganese accumulation induces changes in dopamine metabolism in the cirrhotic rat. Brain Res. 891:2001;123-129
    • (2001) Brain Res. , vol.891 , pp. 123-129
    • Montes, S.1    Alcaraz-Zubeldia, M.2    Muriel, P.3    Rios, C.4
  • 45
    • 0033032593 scopus 로고    scopus 로고
    • Animal models of manganese's neurotoxicity
    • Newland M.C. Animal models of manganese's neurotoxicity. Neurotoxicology. 20:1999;415-432
    • (1999) Neurotoxicology , vol.20 , pp. 415-432
    • Newland, M.C.1
  • 46
    • 0026544324 scopus 로고
    • Metabolic compartmentation of glutamate and glutamine: Morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum
    • Ottersen O.P., Zhang N., Walberg F. Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum. Neuroscience. 46:1992;519-534
    • (1992) Neuroscience , vol.46 , pp. 519-534
    • Ottersen, O.P.1    Zhang, N.2    Walberg, F.3
  • 47
  • 48
    • 0026583465 scopus 로고
    • Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
    • Przedborski S., Kostic V., Jackson-Lewis V., Naini A.B., Simonetti S., Fahn S., et al. Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. J. Neurosci. 12:1992;1658-1667
    • (1992) J. Neurosci. , vol.12 , pp. 1658-1667
    • Przedborski, S.1    Kostic, V.2    Jackson-Lewis, V.3    Naini, A.B.4    Simonetti, S.5    Fahn, S.6
  • 49
    • 0018900962 scopus 로고
    • Chronic manganese oxide administration to preweaning rats: Manganese accumulation and distribution
    • Rehnberg G.L., Hein J.F., Carter S.D., Linko R.S., Laskey J.W. Chronic manganese oxide administration to preweaning rats: manganese accumulation and distribution. J. Toxicol. Environ. Health. 6:1982;217-226
    • (1982) J. Toxicol. Environ. Health , vol.6 , pp. 217-226
    • Rehnberg, G.L.1    Hein, J.F.2    Carter, S.D.3    Linko, R.S.4    Laskey, J.W.5
  • 52
    • 0027428818 scopus 로고
    • The effects of 6-hydroxydopamine and oxidative stress on the level of brain metallothionein
    • Shiraga H., Pfeiffer R.F., Ebadi M. The effects of 6-hydroxydopamine and oxidative stress on the level of brain metallothionein. Neurochem. Int. 23:1993;561-566
    • (1993) Neurochem. Int. , vol.23 , pp. 561-566
    • Shiraga, H.1    Pfeiffer, R.F.2    Ebadi, M.3
  • 53
    • 0029897793 scopus 로고    scopus 로고
    • Manganese-induced hydroxyl radical formation in rat striatum is not attenuated by dopamine depletion or iron chelation in vivo
    • Sloot W.N., Korf J., Koster J.F., DeWit L.E.A., Gramsbergen J.B.P. Manganese-induced hydroxyl radical formation in rat striatum is not attenuated by dopamine depletion or iron chelation in vivo. Exp. Neurol. 138:1996;236-245
    • (1996) Exp. Neurol. , vol.138 , pp. 236-245
    • Sloot, W.N.1    Korf, J.2    Koster, J.F.3    Dewit, L.E.A.4    Gramsbergen, J.B.P.5
  • 54
    • 0032860368 scopus 로고    scopus 로고
    • Whole blood manganese levels in pregnancy and the neonate
    • Spencer A. Whole blood manganese levels in pregnancy and the neonate. Nutrition. 15:1999;731-734
    • (1999) Nutrition , vol.15 , pp. 731-734
    • Spencer, A.1
  • 55
    • 0026795635 scopus 로고
    • Protein oxidation and aging
    • Stadtman E.R. Protein oxidation and aging. Science. 257:1992;1220-1224
    • (1992) Science , vol.257 , pp. 1220-1224
    • Stadtman, E.R.1
  • 56
    • 0033965940 scopus 로고    scopus 로고
    • Dopamine toxicity in neuroblastoma cells: Role of glutathione depletion by L-BSO and apoptosis
    • Stokes A.H., Lewis D.Y., Lash L.H., Jerome W.G., Grant K.W., Aschner M., et al. Dopamine toxicity in neuroblastoma cells: role of glutathione depletion by L-BSO and apoptosis. Brain Res. 858:2000;1-8
    • (2000) Brain Res. , vol.858 , pp. 1-8
    • Stokes, A.H.1    Lewis, D.Y.2    Lash, L.H.3    Jerome, W.G.4    Grant, K.W.5    Aschner, M.6
  • 59
    • 0033119279 scopus 로고    scopus 로고
    • Manganese uptake into rat brain during development and aging
    • Takeda A., Ishiwatari S., Okada S. Manganese uptake into rat brain during development and aging. J. Neurosci. Res. 56:1999;93-98
    • (1999) J. Neurosci. Res. , vol.56 , pp. 93-98
    • Takeda, A.1    Ishiwatari, S.2    Okada, S.3
  • 60
    • 0032145886 scopus 로고    scopus 로고
    • Glutamate transporters are oxidant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration?
    • Trotti D., Danbolt N.C., Volterra A. Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol. Sci. 19:1998;328-334
    • (1998) Trends Pharmacol. Sci. , vol.19 , pp. 328-334
    • Trotti, D.1    Danbolt, N.C.2    Volterra, A.3
  • 61
    • 0015071185 scopus 로고
    • A simulation study of brain compartments - Metabolism of glutamate and related substances in mouse brain
    • Van den Berg C.J., Garfinkel D. A simulation study of brain compartments - metabolism of glutamate and related substances in mouse brain. Biochem. J. 123:1971;211-218
    • (1971) Biochem. J. , vol.123 , pp. 211-218
    • Van Den Berg, C.J.1    Garfinkel, D.2
  • 62
    • 0022478666 scopus 로고
    • Exogenous glutamate is metabolized to glutamine and exported by primary astrocyte cultures
    • Waniewski R.A., Martin D.L. Exogenous glutamate is metabolized to glutamine and exported by primary astrocyte cultures. J. Neurochem. 47:1986;304-313
    • (1986) J. Neurochem. , vol.47 , pp. 304-313
    • Waniewski, R.A.1    Martin, D.L.2
  • 63
    • 0036628677 scopus 로고    scopus 로고
    • Effects of Manganese (Mn) on the developing rat brain: Oxidative-stress related endpoints
    • Weber S., Dorman D.C., Lash L.H., Erikson K., Vrana K.E., Aschner M. Effects of Manganese (Mn) on the developing rat brain: oxidative-stress related endpoints. Neurotoxicology. 23:2002;169-175
    • (2002) Neurotoxicology , vol.23 , pp. 169-175
    • Weber, S.1    Dorman, D.C.2    Lash, L.H.3    Erikson, K.4    Vrana, K.E.5    Aschner, M.6
  • 64
    • 0024785884 scopus 로고
    • Manganese (II) dynamics and distribution in glial cells cultured from chick cerebral cortex
    • Wedler F.C., Ley B.W., Grippo A.A. Manganese (II) dynamics and distribution in glial cells cultured from chick cerebral cortex. Biochem. Res. 14:1989;1129-1135
    • (1989) Biochem. Res. , vol.14 , pp. 1129-1135
    • Wedler, F.C.1    Ley, B.W.2    Grippo, A.A.3
  • 65
    • 0028879327 scopus 로고
    • Metabolic trafficking between neurons and astrocytes: The glutamate glutamine cycle revisited
    • Westergaard N., Sonnewald U., Schousboe A. Metabolic trafficking between neurons and astrocytes: the glutamate glutamine cycle revisited. Dev. Neurosci. 17:1995;203-211
    • (1995) Dev. Neurosci. , vol.17 , pp. 203-211
    • Westergaard, N.1    Sonnewald, U.2    Schousboe, A.3
  • 66
    • 0033201426 scopus 로고    scopus 로고
    • Characterization of manganese-containing particles collected form the exhaust emissions of automobiles running with MMT additive
    • Zayed J., Hong B., L'Esperance G. Characterization of manganese-containing particles collected form the exhaust emissions of automobiles running with MMT additive. Environ. Sci. Technol. 33:1999;3341-3346
    • (1999) Environ. Sci. Technol. , vol.33 , pp. 3341-3346
    • Zayed, J.1    Hong, B.2    L'Esperance, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.