-
1
-
-
0024360388
-
The biology of interleukin-6
-
Kishimoto T. The biology of interleukin-6. Blood 1989; 74:1-10.
-
(1989)
Blood
, vol.74
, pp. 1-10
-
-
Kishimoto, T.1
-
2
-
-
17644368573
-
Interleukin-6: from basic science to medicine-40 years in immunology
-
Kishimoto T. Interleukin-6: from basic science to medicine-40 years in immunology. Annu Rev Immunol 2005; 23:1-21.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 1-21
-
-
Kishimoto, T.1
-
3
-
-
0037066427
-
The danger model: a renewed sense of self
-
Matzinger P. The danger model: a renewed sense of self. Science 2002; 296:301-305.
-
(2002)
Science
, vol.296
, pp. 301-305
-
-
Matzinger, P.1
-
4
-
-
0025190892
-
Interleukin-6 and the acute phase response
-
Heinrich PC, Castell JV, Andus T. Interleukin-6 and the acute phase response. Biochem J 1990; 265:621-636.
-
(1990)
Biochem J
, vol.265
, pp. 621-636
-
-
Heinrich, P.C.1
Castell, J.V.2
Andus, T.3
-
5
-
-
49149095841
-
Transcriptional complex formation of c-Fos, STAT3, and hepatocyte NF-1 alpha is essential for cytokine-driven C-reactive protein gene expression
-
Nishikawa T, Hagihara K, Serada S etal. Transcriptional complex formation of c-Fos, STAT3, and hepatocyte NF-1 alpha is essential for cytokine-driven C-reactive protein gene expression. J Immunol 2008; 180:3492-3501.
-
(2008)
J Immunol
, vol.180
, pp. 3492-3501
-
-
Nishikawa, T.1
Hagihara, K.2
Serada, S.3
-
6
-
-
69349093225
-
Interleukin-17 and type 17 helper T cells
-
Miossec P, Korn T, Kuchroo VK. Interleukin-17 and type 17 helper T cells. N Engl J Med 2009; 361:888-898.
-
(2009)
N Engl J Med
, vol.361
, pp. 888-898
-
-
Miossec, P.1
Korn, T.2
Kuchroo, V.K.3
-
7
-
-
79251543298
-
The influence of excessive IL-6 production in vivo on the development and function of Foxp3+ regulatory T cells
-
Fujimoto M, Nakano M, Terabe F etal. The influence of excessive IL-6 production in vivo on the development and function of Foxp3+ regulatory T cells. J Immunol 2011; 186:32-40.
-
(2011)
J Immunol
, vol.186
, pp. 32-40
-
-
Fujimoto, M.1
Nakano, M.2
Terabe, F.3
-
8
-
-
77954096689
-
IL-6: regulator of Treg/Th17 balance
-
Kimura A, Kishimoto T. IL-6: regulator of Treg/Th17 balance. Eur J Immunol 2010; 40:1830-1835.
-
(2010)
Eur J Immunol
, vol.40
, pp. 1830-1835
-
-
Kimura, A.1
Kishimoto, T.2
-
9
-
-
80053262406
-
Human FoxP3+ regulatory T cells in systemic autoimmune diseases
-
Miyara M, Gorochov G, Ehrenstein M, Musset L, Sakaguchi S, Amoura Z. Human FoxP3+ regulatory T cells in systemic autoimmune diseases. Autoimmun Rev 2011; 10:744-755.
-
(2011)
Autoimmun Rev
, vol.10
, pp. 744-755
-
-
Miyara, M.1
Gorochov, G.2
Ehrenstein, M.3
Musset, L.4
Sakaguchi, S.5
Amoura, Z.6
-
10
-
-
0023803252
-
IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells
-
Okada M, Kitahara M, Kishimoto S, Matsuda T, Hirano T, Kishimoto T. IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells. J Immunol 1988; 141:1543-1549.
-
(1988)
J Immunol
, vol.141
, pp. 1543-1549
-
-
Okada, M.1
Kitahara, M.2
Kishimoto, S.3
Matsuda, T.4
Hirano, T.5
Kishimoto, T.6
-
11
-
-
0024446495
-
Interleukin-6 is a potent thrombopoietic factor in vivo in mice
-
Ishibashi T, Kimura H, Shikama Y etal. Interleukin-6 is a potent thrombopoietic factor in vivo in mice. Blood 1989; 74:1241-1244.
-
(1989)
Blood
, vol.74
, pp. 1241-1244
-
-
Ishibashi, T.1
Kimura, H.2
Shikama, Y.3
-
12
-
-
13344250490
-
Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation
-
Kotake S, Sato K, Kim KJ etal. Interleukin-6 and soluble interleukin-6 receptors in the synovial fluids from rheumatoid arthritis patients are responsible for osteoclast-like cell formation. J Bone Miner Res 1996; 11:88-95.
-
(1996)
J Bone Miner Res
, vol.11
, pp. 88-95
-
-
Kotake, S.1
Sato, K.2
Kim, K.J.3
-
13
-
-
0038798085
-
Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis
-
Nakahara H, Song J, Sugimoto M etal. Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis. Arthritis Rheum 2003; 48:1521-1529.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 1521-1529
-
-
Nakahara, H.1
Song, J.2
Sugimoto, M.3
-
14
-
-
0343019918
-
Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes
-
Grossman RM, Krueger J, Yourish D etal. Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes. Proc Natl Acad Sci USA 1989; 86:6367-6371.
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 6367-6371
-
-
Grossman, R.M.1
Krueger, J.2
Yourish, D.3
-
15
-
-
84872176452
-
Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB
-
Gillespie EF, Raychaudhuri N, Papageorgiou KI etal. Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB. Invest Ophthalmol Vis Sci 2012; 53:7746-7753.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 7746-7753
-
-
Gillespie, E.F.1
Raychaudhuri, N.2
Papageorgiou, K.I.3
-
17
-
-
84869755800
-
Targeting interleukin-6: all the way to treat autoimmune and inflammatory diseases
-
Tanaka T, Kishimoto T. Targeting interleukin-6: all the way to treat autoimmune and inflammatory diseases. Int J Biol Sci 2012; 8:1227-1236.
-
(2012)
Int J Biol Sci
, vol.8
, pp. 1227-1236
-
-
Tanaka, T.1
Kishimoto, T.2
-
18
-
-
0038609651
-
Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex
-
Boulanger MJ, Chow DC, Brevnova EE, Garcia KC. Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex. Science 2003; 300:2101-2104.
-
(2003)
Science
, vol.300
, pp. 2101-2104
-
-
Boulanger, M.J.1
Chow, D.C.2
Brevnova, E.E.3
Garcia, K.C.4
-
19
-
-
57349083145
-
Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses
-
Fujimoto M, Serada S, Mihara M etal. Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses. Arthritis Rheum 2008; 58:3710-3719.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 3710-3719
-
-
Fujimoto, M.1
Serada, S.2
Mihara, M.3
-
20
-
-
33750011260
-
Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus
-
Liang B, Gardner DB, Griswold DE, Bugelski PJ, Song XY. Anti-interleukin-6 monoclonal antibody inhibits autoimmune responses in a murine model of systemic lupus erythematosus. Immunology 2006; 119:296-305.
-
(2006)
Immunology
, vol.119
, pp. 296-305
-
-
Liang, B.1
Gardner, D.B.2
Griswold, D.E.3
Bugelski, P.J.4
Song, X.Y.5
-
21
-
-
83455230778
-
Blockade of interleukin-6 receptor alleviates disease in mouse model of scleroderma
-
Kitaba S, Murota H, Terao M etal. Blockade of interleukin-6 receptor alleviates disease in mouse model of scleroderma. Am J Pathol 2012; 180:165-176.
-
(2012)
Am J Pathol
, vol.180
, pp. 165-176
-
-
Kitaba, S.1
Murota, H.2
Terao, M.3
-
22
-
-
0025183151
-
Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice
-
Brandt SJ, Bodine DM, Dunbar CE, Nienhuis AW. Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. J Clin Invest 1990; 86:592-599.
-
(1990)
J Clin Invest
, vol.86
, pp. 592-599
-
-
Brandt, S.J.1
Bodine, D.M.2
Dunbar, C.E.3
Nienhuis, A.W.4
-
23
-
-
77954952358
-
Blockade of interleukin-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses
-
Hohki S, Ohguro N, Haruta H etal. Blockade of interleukin-6 signaling suppresses experimental autoimmune uveoretinitis by the inhibition of inflammatory Th17 responses. Exp Eye Res 2010; 91:162-170.
-
(2010)
Exp Eye Res
, vol.91
, pp. 162-170
-
-
Hohki, S.1
Ohguro, N.2
Haruta, H.3
-
24
-
-
79961008060
-
Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulatory T cells in experimental autoimmune uveoretinitis
-
Haruta H, Ohguro N, Fujimoto M etal. Blockade of interleukin-6 signaling suppresses not only th17 but also interphotoreceptor retinoid binding protein-specific Th1 by promoting regulatory T cells in experimental autoimmune uveoretinitis. Invest Ophthalmol Vis Sci 2011; 52:3264-3271.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 3264-3271
-
-
Haruta, H.1
Ohguro, N.2
Fujimoto, M.3
-
25
-
-
48249148236
-
IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis
-
Serada S, Fujimoto M, Mihara M etal. IL-6 blockade inhibits the induction of myelin antigen-specific Th17 cells and Th1 cells in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 2008; 105:9041-9046.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9041-9046
-
-
Serada, S.1
Fujimoto, M.2
Mihara, M.3
-
26
-
-
84880084417
-
Can IL-6 blockade rectify imbalance between Tregs and Th17 cells?
-
Tanaka T. Can IL-6 blockade rectify imbalance between Tregs and Th17 cells? Immunotherapy 2013; 5:695-697.
-
(2013)
Immunotherapy
, vol.5
, pp. 695-697
-
-
Tanaka, T.1
-
27
-
-
84891847947
-
Targeting interleukin-6 in inflammatory autoimmune diseases and cancers
-
Yao X, Huang J, Zhong H etal. Targeting interleukin-6 in inflammatory autoimmune diseases and cancers. Pharmacol Ther 2014; 141:125-139.
-
(2014)
Pharmacol Ther
, vol.141
, pp. 125-139
-
-
Yao, X.1
Huang, J.2
Zhong, H.3
-
28
-
-
40749114497
-
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial
-
OPTION Investigators.
-
Smolen JS, Beaulieu A, Rubbert-Roth A etal., OPTION Investigators. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial. Lancet 2008; 371:987-997.
-
(2008)
Lancet
, vol.371
, pp. 987-997
-
-
Smolen, J.S.1
Beaulieu, A.2
Rubbert-Roth, A.3
-
29
-
-
40749152243
-
Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal Phase III trial
-
Yokota S, Imagawa T, Mori M etal. Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal Phase III trial. Lancet 2008; 371:998-1006.
-
(2008)
Lancet
, vol.371
, pp. 998-1006
-
-
Yokota, S.1
Imagawa, T.2
Mori, M.3
-
30
-
-
27144488346
-
Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease
-
Nishimoto N, Kanakura Y, Aozasa K etal. Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood 2005; 106:2627-2632.
-
(2005)
Blood
, vol.106
, pp. 2627-2632
-
-
Nishimoto, N.1
Kanakura, Y.2
Aozasa, K.3
-
31
-
-
84875729559
-
Induction of severe systemic lupus erythematosus by TNF blockade and response to anti-IL-6 strategy
-
1237.e1
-
Adler S, Kolev M, Varisco PA etal. Induction of severe systemic lupus erythematosus by TNF blockade and response to anti-IL-6 strategy. J Allergy Clin Immunol 2013; 131:1235-1237, 1237.e1.
-
(2013)
J Allergy Clin Immunol
, vol.131
, pp. 1235-1237
-
-
Adler, S.1
Kolev, M.2
Varisco, P.A.3
-
32
-
-
78049421175
-
The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab
-
Shima Y, Kuwahara Y, Murota H etal. The skin of patients with systemic sclerosis softened during the treatment with anti-IL-6 receptor antibody tocilizumab. Rheumatology (Oxf) 2010; 49:2408-2412.
-
(2010)
Rheumatology (Oxf)
, vol.49
, pp. 2408-2412
-
-
Shima, Y.1
Kuwahara, Y.2
Murota, H.3
-
33
-
-
79959478448
-
Therapeutic effect of tocilizumab on two patients with polymyositis
-
Narazaki M, Hagihara K, Shima Y, Ogata A, Kishimoto T, Tanaka T. Therapeutic effect of tocilizumab on two patients with polymyositis. Rheumatology (Oxf) 2011; 50:1344-1346.
-
(2011)
Rheumatology (Oxf)
, vol.50
, pp. 1344-1346
-
-
Narazaki, M.1
Hagihara, K.2
Shima, Y.3
Ogata, A.4
Kishimoto, T.5
Tanaka, T.6
-
34
-
-
84890798641
-
Clinical and biological efficacy of tocilizumab in giant cell arteritis: report of three patients and literature review
-
Kieffer P, Hinschberger O, Ciobanu E etal. Clinical and biological efficacy of tocilizumab in giant cell arteritis: report of three patients and literature review. Rev Med Interne 2014; 35:56-59.
-
(2014)
Rev Med Interne
, vol.35
, pp. 56-59
-
-
Kieffer, P.1
Hinschberger, O.2
Ciobanu, E.3
-
35
-
-
84861483650
-
A case of Behçet's disease treated with a humanized anti-interleukin-6 receptor antibody, tocilizumab
-
Hirano T, Ohguro N, Hohki S etal. A case of Behçet's disease treated with a humanized anti-interleukin-6 receptor antibody, tocilizumab. Mod Rheumatol 2012; 22:298-302.
-
(2012)
Mod Rheumatol
, vol.22
, pp. 298-302
-
-
Hirano, T.1
Ohguro, N.2
Hohki, S.3
-
36
-
-
84898875099
-
Current and future treatments for Behçet's uveitis: road to remission
-
Jun 1. [Epub ahead of print].
-
Mesquida M, Molins B, Llorenç V etal. Current and future treatments for Behçet's uveitis: road to remission. Int Ophthalmol 2013; Jun 1. [Epub ahead of print].
-
(2013)
Int Ophthalmol
-
-
Mesquida, M.1
Molins, B.2
Llorenç, V.3
-
37
-
-
0036898472
-
Humanized monoclonal anti-interleukin-6 receptor antibody for treatment of intractable adult-onset Still's disease
-
Iwamoto M, Nara H, Hirata D, Minota S, Nishimoto N, Yoshizaki K. Humanized monoclonal anti-interleukin-6 receptor antibody for treatment of intractable adult-onset Still's disease. Arthritis Rheum 2002; 46:3388-3389.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 3388-3389
-
-
Iwamoto, M.1
Nara, H.2
Hirata, D.3
Minota, S.4
Nishimoto, N.5
Yoshizaki, K.6
-
38
-
-
11144358366
-
A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease
-
discussion 947.
-
Ito H, Takazoe M, Fukuda Y etal. A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease. Gastroenterology 2004; 126:989-996; discussion 947.
-
(2004)
Gastroenterology
, vol.126
, pp. 989-996
-
-
Ito, H.1
Takazoe, M.2
Fukuda, Y.3
-
39
-
-
84879985398
-
Treatment of relapsing polychondritis with tocilizumab
-
Wendling D, Godfrin-Valnet M, Prati C. Treatment of relapsing polychondritis with tocilizumab. J Rheumatol 2013; 40:1232.
-
(2013)
J Rheumatol
, vol.40
, pp. 1232
-
-
Wendling, D.1
Godfrin-Valnet, M.2
Prati, C.3
-
42
-
-
84892636905
-
Tocilizumab for retinal vasoproliferative tumor secondary to juvenile idiopathic arthritis-associated uveitis: a case report
-
Adán A, Mesquida M, Llorenç V, Modesto C. Tocilizumab for retinal vasoproliferative tumor secondary to juvenile idiopathic arthritis-associated uveitis: a case report. Graefes Arch Clin Exp Ophthalmol 2014; 252:163-164.
-
(2014)
Graefes Arch Clin Exp Ophthalmol
, vol.252
, pp. 163-164
-
-
Adán, A.1
Mesquida, M.2
Llorenç, V.3
Modesto, C.4
-
43
-
-
84861800400
-
Is tocilizumab an effective option for treatment of refractory uveitis associated with juvenile idiopathic arthritis?
-
Tappeiner C, Heinz C, Ganser G, Heiligenhaus A. Is tocilizumab an effective option for treatment of refractory uveitis associated with juvenile idiopathic arthritis? J Rheumatol 2012; 39:1294-1295.
-
(2012)
J Rheumatol
, vol.39
, pp. 1294-1295
-
-
Tappeiner, C.1
Heinz, C.2
Ganser, G.3
Heiligenhaus, A.4
-
44
-
-
80053632353
-
Efficacy of tocilizumab in two patients with anti-TNF-alpha refractory uveitis
-
Muselier A, Bielefeld P, Bidot S, Vinit J, Besancenot JF, Bron A. Efficacy of tocilizumab in two patients with anti-TNF-alpha refractory uveitis. Ocul Immunol Inflamm 2011; 19:382-383.
-
(2011)
Ocul Immunol Inflamm
, vol.19
, pp. 382-383
-
-
Muselier, A.1
Bielefeld, P.2
Bidot, S.3
Vinit, J.4
Besancenot, J.F.5
Bron, A.6
-
45
-
-
83255170953
-
Successful treatment of acquired hemophilia A, complicated by chronic GVHD, with tocilizumab
-
Nishida S, Kawasaki T, Kashiwagi H etal. Successful treatment of acquired hemophilia A, complicated by chronic GVHD, with tocilizumab. Mod Rheumatol 2011; 21:420-422.
-
(2011)
Mod Rheumatol
, vol.21
, pp. 420-422
-
-
Nishida, S.1
Kawasaki, T.2
Kashiwagi, H.3
-
46
-
-
84867115230
-
Tocilizumab for treating refractory haemolytic anaemia in a patient with systemic lupus erythematosus
-
García-Hernández FJ, González-León R, Castillo-Palma MJ, Ocaña-Medina C, Sánchez-Román J. Tocilizumab for treating refractory haemolytic anaemia in a patient with systemic lupus erythematosus. Rheumatology (Oxf) 2012; 51:1918-1919.
-
(2012)
Rheumatology (Oxf)
, vol.51
, pp. 1918-1919
-
-
García-Hernández, F.J.1
González-León, R.2
Castillo-Palma, M.J.3
Ocaña-Medina, C.4
Sánchez-Román, J.5
-
47
-
-
84893543095
-
Comparison of the clinical utility of tocilizumab and anti-TNF therapy in AA amyloidosis complicating rheumatic diseases
-
Okuda Y, Ohnishi M, Matoba K etal. Comparison of the clinical utility of tocilizumab and anti-TNF therapy in AA amyloidosis complicating rheumatic diseases. Mod Rheumatol 2014; 24:137-143.
-
(2014)
Mod Rheumatol
, vol.24
, pp. 137-143
-
-
Okuda, Y.1
Ohnishi, M.2
Matoba, K.3
-
48
-
-
81255163590
-
Tocilizumab for the treatment of steroid refractory graft-versus-host disease
-
Drobyski WR, Pasquini M, Kovatovic K etal. Tocilizumab for the treatment of steroid refractory graft-versus-host disease. Biol Blood Marrow Transplant 2011; 17:1862-1868.
-
(2011)
Biol Blood Marrow Transplant
, vol.17
, pp. 1862-1868
-
-
Drobyski, W.R.1
Pasquini, M.2
Kovatovic, K.3
-
49
-
-
84858407842
-
Tocilizumab-a novel therapy for non-organ-specific autoimmune diseases
-
Kaly L, Rosner I. Tocilizumab-a novel therapy for non-organ-specific autoimmune diseases. Best Pract Res Clin Rheumatol 2012; 26:157-165.
-
(2012)
Best Pract Res Clin Rheumatol
, vol.26
, pp. 157-165
-
-
Kaly, L.1
Rosner, I.2
-
50
-
-
84878541159
-
Tocilizumab: a novel humanized anti-interleukin 6 (IL-6) receptor antibody for the treatment of patients with non-RA systemic, inflammatory rheumatic diseases
-
Alten R, Maleitzke T. Tocilizumab: a novel humanized anti-interleukin 6 (IL-6) receptor antibody for the treatment of patients with non-RA systemic, inflammatory rheumatic diseases. Ann Med 2013; 45:357-363.
-
(2013)
Ann Med
, vol.45
, pp. 357-363
-
-
Alten, R.1
Maleitzke, T.2
-
51
-
-
79955807238
-
Improvement of HbA1c during treatment with humanised anti-interleukin 6 receptor antibody, tocilizumab
-
Ogata A, Morishima A, Hirano T etal. Improvement of HbA1c during treatment with humanised anti-interleukin 6 receptor antibody, tocilizumab. Ann Rheum Dis 2011; 70:1164-1165.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1164-1165
-
-
Ogata, A.1
Morishima, A.2
Hirano, T.3
-
52
-
-
7044234496
-
Elevated levels of interleukin 6 in the vitreous fluid of patients with pars planitis and posterior uveitis: the Massachusetts eye and ear experience and review of previous studies
-
Perez VL, Papaliodis GN, Chu D, Anzaar F, Christen W, Foster CS. Elevated levels of interleukin 6 in the vitreous fluid of patients with pars planitis and posterior uveitis: the Massachusetts eye and ear experience and review of previous studies. Ocul Immunol Inflamm 2004; 12:193-201.
-
(2004)
Ocul Immunol Inflamm
, vol.12
, pp. 193-201
-
-
Perez, V.L.1
Papaliodis, G.N.2
Chu, D.3
Anzaar, F.4
Christen, W.5
Foster, C.S.6
-
53
-
-
33644694952
-
Multiplex bead immunoassay analysis of aqueous humor reveals distinct cytokine profiles in uveitis
-
Curnow SJ, Falciani F, Durrani OM etal. Multiplex bead immunoassay analysis of aqueous humor reveals distinct cytokine profiles in uveitis. Invest Ophthalmol Vis Sci 2005; 46:4251-4259.
-
(2005)
Invest Ophthalmol Vis Sci
, vol.46
, pp. 4251-4259
-
-
Curnow, S.J.1
Falciani, F.2
Durrani, O.M.3
-
55
-
-
0022641533
-
T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat
-
Caspi RR, Roberge FG, McAllister CG etal. T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat. J Immunol 1986; 136:928-933.
-
(1986)
J Immunol
, vol.136
, pp. 928-933
-
-
Caspi, R.R.1
Roberge, F.G.2
McAllister, C.G.3
-
56
-
-
34250005444
-
TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1
-
Amadi-Obi A, Yu CR, Liu X etal. TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1. Nat Med 2007; 13:711-718.
-
(2007)
Nat Med
, vol.13
, pp. 711-718
-
-
Amadi-Obi, A.1
Yu, C.R.2
Liu, X.3
-
57
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
Bettelli E, Carrier Y, Gao W etal. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006; 441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
-
58
-
-
63249084553
-
Involvement of Th17 cells and the effect of anti-IL-6 therapy in autoimmune uveitis
-
Yoshimura T, Sonoda KH, Ohguro N etal. Involvement of Th17 cells and the effect of anti-IL-6 therapy in autoimmune uveitis. Rheumatology (Oxf) 2009; 48:347-354.
-
(2009)
Rheumatology (Oxf)
, vol.48
, pp. 347-354
-
-
Yoshimura, T.1
Sonoda, K.H.2
Ohguro, N.3
-
59
-
-
84887196014
-
Tocilizumab treatment for refractory uveitis-related cystoid macular edema
-
Adán A, Mesquida M, Llorenç V etal. Tocilizumab treatment for refractory uveitis-related cystoid macular edema. Graefes Arch Clin Exp Ophthalmol 2013; 251:2627-2632.
-
(2013)
Graefes Arch Clin Exp Ophthalmol
, vol.251
, pp. 2627-2632
-
-
Adán, A.1
Mesquida, M.2
Llorenç, V.3
-
60
-
-
84873260003
-
Refractory neuro-Behçet treated by tocilizumab: a case report
-
Urbaniak P, Hasler P, Kretzschmar S. Refractory neuro-Behçet treated by tocilizumab: a case report. Clin Exp Rheumatol 2012; 30 (3 Suppl. 72):S73-75.
-
(2012)
Clin Exp Rheumatol
, vol.30
, Issue.3 SUPPL. 72
-
-
Urbaniak, P.1
Hasler, P.2
Kretzschmar, S.3
-
61
-
-
84882600094
-
Refractory uveitis in patient with Castleman disease successfully treated with tocilizumab
-
Oshitari T, Kajita F, Tobe A etal. Refractory uveitis in patient with Castleman disease successfully treated with tocilizumab. Case Rep Ophthalmol Med 2012; 2012:968180.
-
(2012)
Case Rep Ophthalmol Med
, vol.2012
, pp. 968180
-
-
Oshitari, T.1
Kajita, F.2
Tobe, A.3
-
62
-
-
84877730651
-
Successful treatment with tocilizumab in a case of Cogan's syndrome complicated with aortitis
-
Shibuya M, Fujio K, Morita K, Harada H, Kanda H, Yamamoto K. Successful treatment with tocilizumab in a case of Cogan's syndrome complicated with aortitis. Mod Rheumatol 2013; 23:577-581.
-
(2013)
Mod Rheumatol
, vol.23
, pp. 577-581
-
-
Shibuya, M.1
Fujio, K.2
Morita, K.3
Harada, H.4
Kanda, H.5
Yamamoto, K.6
-
63
-
-
84874859809
-
Disease amelioration with tocilizumab in a treatment-resistant patient with neuromyelitis optica: implication for cellular immune responses
-
Kieseier BC, Stüve O, Dehmel T etal. Disease amelioration with tocilizumab in a treatment-resistant patient with neuromyelitis optica: implication for cellular immune responses. JAMA Neurol 2013; 70:390-393.
-
(2013)
JAMA Neurol
, vol.70
, pp. 390-393
-
-
Kieseier, B.C.1
Stüve, O.2
Dehmel, T.3
-
65
-
-
84859615840
-
CD8+CD28-lymphocytes in peripheral blood and serum concentrations of soluble interleukin 6 receptor are increased in patients with Graves' orbitopathy and correlate with disease activity
-
Slowik M, Urbaniak-Kujda D, Bohdanowicz-Pawlak A etal. CD8+CD28-lymphocytes in peripheral blood and serum concentrations of soluble interleukin 6 receptor are increased in patients with Graves' orbitopathy and correlate with disease activity. Endocr Res 2012; 37:89-95.
-
(2012)
Endocr Res
, vol.37
, pp. 89-95
-
-
Slowik, M.1
Urbaniak-Kujda, D.2
Bohdanowicz-Pawlak, A.3
-
66
-
-
84894901070
-
Tocilizumab in rheumatoid arthritis: a meta-analysis of efficacy and selected clinical conundrums
-
Navarro G, Taroumian S, Barroso N, Duan L, Furst D. Tocilizumab in rheumatoid arthritis: a meta-analysis of efficacy and selected clinical conundrums. Semin Arthritis Rheum 2014; 43:458-469.
-
(2014)
Semin Arthritis Rheum
, vol.43
, pp. 458-469
-
-
Navarro, G.1
Taroumian, S.2
Barroso, N.3
Duan, L.4
Furst, D.5
-
67
-
-
84880094171
-
Current perspectives on tocilizumab for the treatment of rheumatoid arthritis: a review
-
Al-Shakarchi I, Gullick NJ, Scott DL. Current perspectives on tocilizumab for the treatment of rheumatoid arthritis: a review. Patient Prefer Adherence 2013; 7:653-666.
-
(2013)
Patient Prefer Adherence
, vol.7
, pp. 653-666
-
-
Al-Shakarchi, I.1
Gullick, N.J.2
Scott, D.L.3
-
68
-
-
84891795508
-
Effectiveness and safety of tocilizumab: postmarketing surveillance of 7901 patients with rheumatoid arthritis in Japan
-
Koike T, Harigai M, Inokuma S etal. Effectiveness and safety of tocilizumab: postmarketing surveillance of 7901 patients with rheumatoid arthritis in Japan. J Rheumatol 2014; 41:15-23.
-
(2014)
J Rheumatol
, vol.41
, pp. 15-23
-
-
Koike, T.1
Harigai, M.2
Inokuma, S.3
-
69
-
-
79952013541
-
Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trials
-
Campbell L, Chen C, Bhagat SS, Parker RA, Östör AJ. Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab: a systematic literature review and meta-analysis of randomized controlled trials. Rheumatology (Oxf) 2011; 50:552-562.
-
(2011)
Rheumatology (Oxf)
, vol.50
, pp. 552-562
-
-
Campbell, L.1
Chen, C.2
Bhagat, S.S.3
Parker, R.A.4
Östör, A.J.5
-
70
-
-
84897429653
-
Biologic therapies and pregnancy: the story so far
-
Dec 17. [Epub ahead of print].
-
Hyrich KL, Verstappen SM. Biologic therapies and pregnancy: the story so far. Rheumatology (Oxf) 2013; Dec 17. [Epub ahead of print].
-
(2013)
Rheumatology (Oxf)
-
-
Hyrich, K.L.1
Verstappen, S.M.2
|