메뉴 건너뛰기




Volumn 17, Issue 12, 2011, Pages 1862-1868

Tocilizumab for the treatment of steroid refractory graft-versus-host disease

Author keywords

Graft versus host disease; Interleukin 6; Steroid refractory; Tocilizumab

Indexed keywords

ALEMTUZUMAB; BUDESONIDE; HYDROCORTISONE; HYDROXYCHLOROQUINE; IMATINIB; INFLIXIMAB; LIDOCAINE; METHOTREXATE; METHYLPREDNISOLONE; METHYLPREDNISOLONE SODIUM SUCCINATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OCTREOTIDE; PREDNISONE; RAPAMYCIN; RITUXIMAB; STEROID; TACROLIMUS; THYMOCYTE ANTIBODY; TOCILIZUMAB;

EID: 81255163590     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2011.07.001     Document Type: Article
Times cited : (97)

References (39)
  • 1
    • 0025190044 scopus 로고
    • Treatment of moderate/severe acute graft versus host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome
    • Weisdorf D., Haake R., Blazar B., et al. Treatment of moderate/severe acute graft versus host disease after allogeneic bone marrow transplantation: an analysis of clinical risk features and outcome. Blood 1990, 75:1024-1030.
    • (1990) Blood , vol.75 , pp. 1024-1030
    • Weisdorf, D.1    Haake, R.2    Blazar, B.3
  • 2
    • 0036048349 scopus 로고    scopus 로고
    • Response of 443 patients to steroids as primary therapy for acute graft versus host disease: comparison of grading systems
    • Macmillan M.L., Weisdorf D.J., Wagner J.E., et al. Response of 443 patients to steroids as primary therapy for acute graft versus host disease: comparison of grading systems. Biol Blood Marrow Transplant 2002, 8:387-394.
    • (2002) Biol Blood Marrow Transplant , vol.8 , pp. 387-394
    • Macmillan, M.L.1    Weisdorf, D.J.2    Wagner, J.E.3
  • 3
    • 0031872983 scopus 로고    scopus 로고
    • Mycophenolate mofetil for the treatment of acute and chronic GVHD in bone marrow transplant patients
    • Basara N., Blau W.I., Romer E., et al. Mycophenolate mofetil for the treatment of acute and chronic GVHD in bone marrow transplant patients. Bone Marrow Transplant 1998, 22:61-65.
    • (1998) Bone Marrow Transplant , vol.22 , pp. 61-65
    • Basara, N.1    Blau, W.I.2    Romer, E.3
  • 4
    • 3042612312 scopus 로고    scopus 로고
    • Different efficacy of mycophenolate mofetil as salvage treatment fro acute and chronic GVHD after allogeneic stem cell transplant
    • Kim J.G., Sohn S.K., Kim D.H., et al. Different efficacy of mycophenolate mofetil as salvage treatment fro acute and chronic GVHD after allogeneic stem cell transplant. Eur J Haematol 2004, 73:56-61.
    • (2004) Eur J Haematol , vol.73 , pp. 56-61
    • Kim, J.G.1    Sohn, S.K.2    Kim, D.H.3
  • 5
    • 21044441501 scopus 로고    scopus 로고
    • Pentostatin in steroid-refractory acute graft versus host disease
    • Bolanos-Meade J., Jacobsohn D.A., Margolis J., et al. Pentostatin in steroid-refractory acute graft versus host disease. J Clin Oncol 2005, 23:2661-2668.
    • (2005) J Clin Oncol , vol.23 , pp. 2661-2668
    • Bolanos-Meade, J.1    Jacobsohn, D.A.2    Margolis, J.3
  • 6
    • 0035660613 scopus 로고    scopus 로고
    • Sirolimus (Rapamycin) for the treatment of steroid-refractory acute graft versus host disease
    • Benito A.I., Furlong T., Martin P.J., et al. Sirolimus (Rapamycin) for the treatment of steroid-refractory acute graft versus host disease. Transplantation 2001, 72:1924-1929.
    • (2001) Transplantation , vol.72 , pp. 1924-1929
    • Benito, A.I.1    Furlong, T.2    Martin, P.J.3
  • 7
    • 77955570085 scopus 로고    scopus 로고
    • Sirolimus for treatment of steroid-refractory acute graft versus host disease
    • Hoda D., Pidala J., Salgado-Vila N., et al. Sirolimus for treatment of steroid-refractory acute graft versus host disease. Bone Marrow Transplant 2010, 45:1347-1351.
    • (2010) Bone Marrow Transplant , vol.45 , pp. 1347-1351
    • Hoda, D.1    Pidala, J.2    Salgado-Vila, N.3
  • 9
    • 0034307671 scopus 로고    scopus 로고
    • Extracorporeal photochemotherapy in the treatment of severe steroid-refractory acute graft versus host disease: a pilot study
    • Greinix H.T., Volc-Platzer B., Kalhs P., et al. Extracorporeal photochemotherapy in the treatment of severe steroid-refractory acute graft versus host disease: a pilot study. Blood 2000, 96:2426-2431.
    • (2000) Blood , vol.96 , pp. 2426-2431
    • Greinix, H.T.1    Volc-Platzer, B.2    Kalhs, P.3
  • 10
    • 3242756749 scopus 로고    scopus 로고
    • Tumor necrosis alpha blockade for the treatment of acute GVHD
    • Couriel D., Saliba R., Hicks K., et al. Tumor necrosis alpha blockade for the treatment of acute GVHD. Blood 2004, 104:649-654.
    • (2004) Blood , vol.104 , pp. 649-654
    • Couriel, D.1    Saliba, R.2    Hicks, K.3
  • 11
    • 3843103590 scopus 로고    scopus 로고
    • Safety and efficacy of denileukin diftitox in patients with steroid-refractory acute graft versus host disease after allogeneic hematopoietic stem cell transplantation
    • Ho V.T., Zahrieh D., Hochberg E., et al. Safety and efficacy of denileukin diftitox in patients with steroid-refractory acute graft versus host disease after allogeneic hematopoietic stem cell transplantation. Blood 2004, 104:1224-1226.
    • (2004) Blood , vol.104 , pp. 1224-1226
    • Ho, V.T.1    Zahrieh, D.2    Hochberg, E.3
  • 12
    • 14244265761 scopus 로고    scopus 로고
    • Denileukin difitox for the treatment of steroid-resistant acute graft versus host disease
    • Shaughnessy P.J., Bachier C., Grimley M., et al. Denileukin difitox for the treatment of steroid-resistant acute graft versus host disease. Biol Blood Marrow Transplant 2005, 11:188-193.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 188-193
    • Shaughnessy, P.J.1    Bachier, C.2    Grimley, M.3
  • 13
    • 33745964855 scopus 로고    scopus 로고
    • Rituximab for steroid-refractory chronic graft versus host disease
    • Cutler C., Miklos D., Kim H.T., et al. Rituximab for steroid-refractory chronic graft versus host disease. Blood 2006, 108:756-762.
    • (2006) Blood , vol.108 , pp. 756-762
    • Cutler, C.1    Miklos, D.2    Kim, H.T.3
  • 14
    • 78651355835 scopus 로고    scopus 로고
    • Therapy of steroid-refractory acute GVHD with CD52 antibody alemtuzumab is effective
    • Schub N., Gunther A., Schrauder A., et al. Therapy of steroid-refractory acute GVHD with CD52 antibody alemtuzumab is effective. Bone Marrow Transplant 2011, 46:143-147.
    • (2011) Bone Marrow Transplant , vol.46 , pp. 143-147
    • Schub, N.1    Gunther, A.2    Schrauder, A.3
  • 15
    • 0030861750 scopus 로고    scopus 로고
    • Total body irradiation and acute graft versus host disease: the role of gastrointestinal damage and inflammatory cytokines
    • Hill G.R., Crawford J.M., Cooke K.R., Brinson Y.S., Pan L., Ferrara J.L. Total body irradiation and acute graft versus host disease: the role of gastrointestinal damage and inflammatory cytokines. Blood 1997, 90:3204-3213.
    • (1997) Blood , vol.90 , pp. 3204-3213
    • Hill, G.R.1    Crawford, J.M.2    Cooke, K.R.3    Brinson, Y.S.4    Pan, L.5    Ferrara, J.L.6
  • 17
    • 0028342413 scopus 로고
    • Serum cytokine levels in bone marrow transplantation: synergistic interaction of interleukin 6, interferon gamma, and tumor necrosis factor alpha in graft versus host disease
    • Imamura M., Hashino S., Kobayashi H., et al. Serum cytokine levels in bone marrow transplantation: synergistic interaction of interleukin 6, interferon gamma, and tumor necrosis factor alpha in graft versus host disease. Bone Marrow Transplant 1994, 13:745-751.
    • (1994) Bone Marrow Transplant , vol.13 , pp. 745-751
    • Imamura, M.1    Hashino, S.2    Kobayashi, H.3
  • 18
    • 0035438384 scopus 로고    scopus 로고
    • Interferon γ and interleukin 6 gene polymorphisms associate with graft versus host disease in HLA-matched sibling bone marrow transplantation
    • Cavet J., Dickinson A.M., Norden J., Taylor P.R.A., Jackson G.H., Middleton P.G. Interferon γ and interleukin 6 gene polymorphisms associate with graft versus host disease in HLA-matched sibling bone marrow transplantation. Blood 2001, 98:1594-1600.
    • (2001) Blood , vol.98 , pp. 1594-1600
    • Cavet, J.1    Dickinson, A.M.2    Norden, J.3    Taylor, P.R.A.4    Jackson, G.H.5    Middleton, P.G.6
  • 19
    • 0035959305 scopus 로고    scopus 로고
    • Both genetic and clinical factors predict the development of graft versus host disease after allogeneic hematopoietic stem cell transplantation
    • Socie G., Loiseau P., Tamouza R., et al. Both genetic and clinical factors predict the development of graft versus host disease after allogeneic hematopoietic stem cell transplantation. Transplantation 2001, 72:699-706.
    • (2001) Transplantation , vol.72 , pp. 699-706
    • Socie, G.1    Loiseau, P.2    Tamouza, R.3
  • 20
    • 68249160054 scopus 로고    scopus 로고
    • Blockade of interleukin 6 signaling augments regulatory T cell reconstitution and attenuates the severity of graft versus host disease
    • Chen X., Das R., Komorowski R., Beres A., Hessner M.J., Mihara M., Drobyski W.R. Blockade of interleukin 6 signaling augments regulatory T cell reconstitution and attenuates the severity of graft versus host disease. Blood 2009, 114:891-900.
    • (2009) Blood , vol.114 , pp. 891-900
    • Chen, X.1    Das, R.2    Komorowski, R.3    Beres, A.4    Hessner, M.J.5    Mihara, M.6    Drobyski, W.R.7
  • 21
    • 78751469023 scopus 로고    scopus 로고
    • Interleukin 6 modulates graft versus host disease after experimental allogeneic bone marrow transplantation
    • Tawara I., Koyama M., Liu C., et al. Interleukin 6 modulates graft versus host disease after experimental allogeneic bone marrow transplantation. Clin Cancer Res 2011, 17:77-88.
    • (2011) Clin Cancer Res , vol.17 , pp. 77-88
    • Tawara, I.1    Koyama, M.2    Liu, C.3
  • 22
    • 2642558925 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with humanized anti-interleukin 6 receptor antibody
    • Nishimoto N., Yoshizaki K., Miyasaka N., et al. Treatment of rheumatoid arthritis with humanized anti-interleukin 6 receptor antibody. Arthritis Rheum 2004, 50:1761-1769.
    • (2004) Arthritis Rheum , vol.50 , pp. 1761-1769
    • Nishimoto, N.1    Yoshizaki, K.2    Miyasaka, N.3
  • 23
    • 40749152243 scopus 로고    scopus 로고
    • Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomized, double-blind, placebo-controlled, withdrawal phase III trial
    • Yokota S., Imagawa T., Mori M., et al. Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomized, double-blind, placebo-controlled, withdrawal phase III trial. Lancet 2008, 371:998-1006.
    • (2008) Lancet , vol.371 , pp. 998-1006
    • Yokota, S.1    Imagawa, T.2    Mori, M.3
  • 24
    • 34250198300 scopus 로고    scopus 로고
    • Anti-interleukin 6 receptor antibody (Tocilizumab) treatment of multicentric Castleman's disease
    • Matsuyama M., Suzuki T., Tsuboi H., et al. Anti-interleukin 6 receptor antibody (Tocilizumab) treatment of multicentric Castleman's disease. Intern Med 2007, 46:771-774.
    • (2007) Intern Med , vol.46 , pp. 771-774
    • Matsuyama, M.1    Suzuki, T.2    Tsuboi, H.3
  • 25
    • 78049508308 scopus 로고    scopus 로고
    • Effectiveness and safety of tocilizumab, an anti-interleukin 6 receptor monoclonal antibody in a patient with refractory GI graft versus host disease
    • Gergis U., Arnason J., Yantiss R., Shore T., Wissa U., Feldman E. Effectiveness and safety of tocilizumab, an anti-interleukin 6 receptor monoclonal antibody in a patient with refractory GI graft versus host disease. J Clin Oncol 2010, 28:e602-e604.
    • (2010) J Clin Oncol , vol.28
    • Gergis, U.1    Arnason, J.2    Yantiss, R.3    Shore, T.4    Wissa, U.5    Feldman, E.6
  • 26
    • 0016187133 scopus 로고
    • Clinical manifestations of graft-versus-host disease in human recipients of marrow from HLA matched sibling donors
    • Glucksberg H., Storb R., Fefer A., et al. Clinical manifestations of graft-versus-host disease in human recipients of marrow from HLA matched sibling donors. Transplantation 1974, 18:295-304.
    • (1974) Transplantation , vol.18 , pp. 295-304
    • Glucksberg, H.1    Storb, R.2    Fefer, A.3
  • 27
    • 28744444180 scopus 로고    scopus 로고
    • National Institutes of Health consensus development project on criteria for clinical trials in chronic graft versus host disease: I. Diagnosis and staging working group report
    • Filipovich A.H., Weisdorf D., Pavletic S., et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft versus host disease: I. Diagnosis and staging working group report. Biol Blood Marrow Transplant 2005, 11:945-956.
    • (2005) Biol Blood Marrow Transplant , vol.11 , pp. 945-956
    • Filipovich, A.H.1    Weisdorf, D.2    Pavletic, S.3
  • 28
    • 33244456998 scopus 로고    scopus 로고
    • Measuring therapeutic response in chronic graft versus host disease: National Institutes of Health Consensus Development Project on criteria for clinical trials in chronic graft versus host disease: IV. Response criteria working group report
    • Pavletic S.Z., Martin P., Lee S.J., et al. Measuring therapeutic response in chronic graft versus host disease: National Institutes of Health Consensus Development Project on criteria for clinical trials in chronic graft versus host disease: IV. Response criteria working group report. Biol Blood Marrow Transplant 2006, 12:252-266.
    • (2006) Biol Blood Marrow Transplant , vol.12 , pp. 252-266
    • Pavletic, S.Z.1    Martin, P.2    Lee, S.J.3
  • 29
    • 63849105635 scopus 로고    scopus 로고
    • Interleukin 23 secretion by donor antigen presenting cells is critical for organ-specific pathology in graft versus host disease
    • Das R., Chen X., Komorowski R., Hessner M.J., Drobyski W.R. Interleukin 23 secretion by donor antigen presenting cells is critical for organ-specific pathology in graft versus host disease. Blood 2009, 113:2352-2362.
    • (2009) Blood , vol.113 , pp. 2352-2362
    • Das, R.1    Chen, X.2    Komorowski, R.3    Hessner, M.J.4    Drobyski, W.R.5
  • 30
    • 77955873442 scopus 로고    scopus 로고
    • Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma
    • Hill G.R., Olver S.D., Kuns R.D., et al. Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma. Blood 2010, 116:819-828.
    • (2010) Blood , vol.116 , pp. 819-828
    • Hill, G.R.1    Olver, S.D.2    Kuns, R.D.3
  • 32
    • 32244442562 scopus 로고    scopus 로고
    • TGF beta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17 producing T cells
    • Veldhoen M., Hocking R.J., Atkins C.J., Locksley R.M., Stockinger B. TGF beta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17 producing T cells. Immunity 2006, 24:179-186.
    • (2006) Immunity , vol.24 , pp. 179-186
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 33
    • 79955569760 scopus 로고    scopus 로고
    • In vivo effect of the anti-interleukin 6 receptor inhibitor tocilizumab on the B cell compartment
    • Roll P., Muhammad K., Schumann M., Kleinert S., Einsele H., Dorner T., Tony H.O. In vivo effect of the anti-interleukin 6 receptor inhibitor tocilizumab on the B cell compartment. Arthritis Rheum 2011 May, 63(5):1255-1264.
    • (2011) Arthritis Rheum , vol.63 , Issue.5 , pp. 1255-1264
    • Roll, P.1    Muhammad, K.2    Schumann, M.3    Kleinert, S.4    Einsele, H.5    Dorner, T.6    Tony, H.O.7
  • 34
    • 0033121274 scopus 로고    scopus 로고
    • Endogenous IL-1 alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A
    • Kawaguchi Y., Hara M., Wright T.M. Endogenous IL-1 alpha from systemic sclerosis fibroblasts induces IL-6 and PDGF-A. J Clin Invest 1999, 103:1253-1260.
    • (1999) J Clin Invest , vol.103 , pp. 1253-1260
    • Kawaguchi, Y.1    Hara, M.2    Wright, T.M.3
  • 35
    • 78049421175 scopus 로고    scopus 로고
    • The skin of patients with systemic sclerosis softened during treatment with anti-IL receptor antibody tocilizumab
    • Shima Y., Kuwahara Y., Murota H., et al. The skin of patients with systemic sclerosis softened during treatment with anti-IL receptor antibody tocilizumab. Rheumatology 2010, 49:2408-2412.
    • (2010) Rheumatology , vol.49 , pp. 2408-2412
    • Shima, Y.1    Kuwahara, Y.2    Murota, H.3
  • 36
    • 70349402169 scopus 로고    scopus 로고
    • Long term safety and efficacy of tocilizumab, an anit-IL-6-receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5 year extension study
    • Nishimoto N., Miyasaka N., Yamamoto K., Kawai S., Takeuchi T., Azuma J. Long term safety and efficacy of tocilizumab, an anit-IL-6-receptor monoclonal antibody, in monotherapy, in patients with rheumatoid arthritis (the STREAM study): evidence of safety and efficacy in a 5 year extension study. Ann Rheum Dis 2009, 68:1580-1584.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1580-1584
    • Nishimoto, N.1    Miyasaka, N.2    Yamamoto, K.3    Kawai, S.4    Takeuchi, T.5    Azuma, J.6
  • 37
    • 79952013541 scopus 로고    scopus 로고
    • Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab; a systematic literature review and meta-analysis of randomized controlled trials
    • Campbell L., Chen C., Bhagat S.S., Parker R.A., Ostor A.J.K. Risk of adverse events including serious infections in rheumatoid arthritis patients treated with tocilizumab; a systematic literature review and meta-analysis of randomized controlled trials. Rheumatology 2011, 50:552-562.
    • (2011) Rheumatology , vol.50 , pp. 552-562
    • Campbell, L.1    Chen, C.2    Bhagat, S.S.3    Parker, R.A.4    Ostor, A.J.K.5
  • 38
    • 0026275041 scopus 로고
    • Pharmacokinetics of intravenous immunoglobulin (Gammagard) in bone marrow transplant patients
    • Rand K.H., Gibbs K., Derendorf H., Graham-Pole J. Pharmacokinetics of intravenous immunoglobulin (Gammagard) in bone marrow transplant patients. J Clin Pharmacol 1991, 31:1151-1154.
    • (1991) J Clin Pharmacol , vol.31 , pp. 1151-1154
    • Rand, K.H.1    Gibbs, K.2    Derendorf, H.3    Graham-Pole, J.4
  • 39
    • 11144358366 scopus 로고    scopus 로고
    • A pilot randomized trial of a human anti-IL-6 receptor monoclonal antibody in active Crohn's disease
    • Ito H., Takazoe M., Fukuda Y., et al. A pilot randomized trial of a human anti-IL-6 receptor monoclonal antibody in active Crohn's disease. Gastroenterology 2004, 126:989-996.
    • (2004) Gastroenterology , vol.126 , pp. 989-996
    • Ito, H.1    Takazoe, M.2    Fukuda, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.