-
1
-
-
84874220237
-
Tocilizumab: An updated review of its use in the treatment of rheumatoid arthritis and its application for other immune-mediated diseases
-
Tanaka T, Ogata A, Narazaki M. Tocilizumab: an updated review of its use in the treatment of rheumatoid arthritis and its application for other immune-mediated diseases. Clin. Med. Insights Ther. 5, 33-52 (2013)
-
(2013)
Clin. Med. Insights Ther
, vol.5
, pp. 33-52
-
-
Tanaka, T.1
Ogata, A.2
Narazaki, M.3
-
2
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
Mclnnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N. Engl. J.Med. 365, 2205-2219 (2011)
-
(2011)
N. Engl. J.Med
, vol.365
, pp. 2205-2219
-
-
McLnnes, I.B.1
Schett, G.2
-
4
-
-
84869755800
-
Targeting interleukin-6: All the way to treat autoimmune and inflammatory diseases
-
Tanaka T, Kishimoto T. Targeting interleukin-6: all the way to treat autoimmune and inflammatory diseases. Int. J.Biol. Sci. 8, 1227-1236 (2012)
-
(2012)
Int. J.Biol. Sci
, vol.8
, pp. 1227-1236
-
-
Tanaka, T.1
Kishimoto, T.2
-
5
-
-
84873286047
-
Effect of interleukin-6 receptor blockade on the balance between regulatory T cells and T helper type 17 cells in rheumatoid arthritis patients
-
Pesce B, Soto L, Sabugo F et al. Effect of interleukin-6 receptor blockade on the balance between regulatory T cells and T helper type 17 cells in rheumatoid arthritis patients. Clin. Exp. Immunol. 171, 237-242 (2012)
-
(2012)
Clin. Exp. Immunol
, vol.171
, pp. 237-242
-
-
Pesce, B.1
Soto, L.2
Sabugo, F.3
-
6
-
-
84864481289
-
Inhibition of interleukin-6 function corrects Th17/Treg cell imbalance in patients with rheumatoid arthritis
-
Samson M, Audia S, Janikashvili N etal. Inhibition of interleukin-6 function corrects Th17/Treg cell imbalance in patients with rheumatoid arthritis. Arthritis Rheum. 64, 2499-2503 (2012)
-
(2012)
Arthritis Rheum
, vol.64
, pp. 2499-2503
-
-
Samson, M.1
Audia, S.2
Janikashvili, N.3
-
7
-
-
84874957237
-
Interleukin-6 receptor blockade selectively reduces IL-21 production by CD4 T cells and IgG4 autoantibodies in rheumatoid arthritis
-
Carbone G, Wilson A, Diehl SA etal. Interleukin-6 receptor blockade selectively reduces IL-21 production by CD4 T cells and IgG4 autoantibodies in rheumatoid arthritis. Int. J.Biol. Sci. 9, 279-288 (2013)
-
(2013)
Int. J.Biol. Sci
, vol.9
, pp. 279-288
-
-
Carbone, G.1
Wilson, A.2
Diehl, S.A.3
-
8
-
-
77954096689
-
IL-6: Regulator of Treg/Th17 balance
-
Kimura A, Kishimoto T. IL-6: regulator of Treg/Th17 balance. Eur. J.Immunol. 40, 1830-1835 (2010)
-
(2010)
Eur. J.Immunol
, vol.40
, pp. 1830-1835
-
-
Kimura, A.1
Kishimoto, T.2
-
9
-
-
79955569760
-
Invivo effect of the anti-interleukin-6 receptor inhibitor tocilizumab on the B-cell compartment
-
Roll P, Muhammad K, Schumann M etal. Invivo effect of the anti-interleukin-6 receptor inhibitor tocilizumab on the B-cell compartment. Arthritis Rheum. 63, 1255-1264 (2011)
-
(2011)
Arthritis Rheum
, vol.63
, pp. 1255-1264
-
-
Roll, P.1
Muhammad, K.2
Schumann, M.3
-
10
-
-
79959807954
-
Impact of IL-6 receptor inhibition on human memory B cells invivo: Impaired somatic hypermutation in preswitch memory B cells and modulation of mutational targeting in memory B cells
-
Muhammad K, Roll P, Seibold T etal. Impact of IL-6 receptor inhibition on human memory B cells invivo: impaired somatic hypermutation in preswitch memory B cells and modulation of mutational targeting in memory B cells. Ann. Rheum. Dis. 70, 1507-1510 (2011)
-
(2011)
Ann. Rheum. Dis
, vol.70
, pp. 1507-1510
-
-
Muhammad, K.1
Roll, P.2
Seibold, T.3
-
11
-
-
84880844455
-
Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab
-
doi:10.1007/s10165-012-0715-9 (Epub ahead of print)
-
Araki M, Aranami T, Matsuoka T, Nakamura M, Miyake S, Yamamura T. Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab. Mod. Rheumatol. doi:10.1007/s10165-012-0715-9 (2012) (Epub ahead of print)
-
(2012)
Mod. Rheumatol
-
-
Araki, M.1
Aranami, T.2
Matsuoka, T.3
Nakamura, M.4
Miyake, S.5
Yamamura, T.6
-
12
-
-
84876227342
-
Disease amelioration with tocilizumab in a treatment-resistant patient with neuromyelitis optica: Implication for cellular immune responses
-
Kieseier BC, Stuve O, Dehmel T etal. Disease amelioration with tocilizumab in a treatment-resistant patient with neuromyelitis optica: implication for cellular immune responses. Arch. Neurol. 24, 1-4 (2012)
-
(2012)
Arch. Neurol
, vol.24
, pp. 1-4
-
-
Kieseier, B.C.1
Stuve, O.2
Dehmel, T.3
-
13
-
-
84874904135
-
Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy
-
Ayzenberg I, Kleiter I, Schroder A etal. Interleukin 6 receptor blockade in patients with neuromyelitis optica nonresponsive to anti-CD20 therapy. JAMA Neurol. 70, 394-397 (2013)
-
(2013)
JAMA Neurol
, vol.70
, pp. 394-397
-
-
Ayzenberg, I.1
Kleiter, I.2
Schroder, A.3
-
14
-
-
79952762854
-
Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica
-
Chihara N, Aranami T, Sato W etal. Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica. Proc. Natl Acad. Sci. USA 108, 3701-3706 (2011)
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 3701-3706
-
-
Chihara, N.1
Aranami, T.2
Sato, W.3
-
15
-
-
84867917889
-
Interleukin-6: From an inflammatory marker to a target for inflammatory diseases
-
Rincon M. Interleukin-6: from an inflammatory marker to a target for inflammatory diseases. Trends Immunol. 33, 571-577 (2012)
-
(2012)
Trends Immunol
, vol.33
, pp. 571-577
-
-
Rincon, M.1
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