Reactive oxygen species contribute to arsenic-induced EZH2 phosphorylation in human bronchial epithelial cells and lung cancer cells

Toxicology and Applied Pharmacology

Volumn 276, Issue 3, 2014, Pages 165-170

  Li, Lingzhi ^a   Qiu, Ping ^a   Chen, Bailing ^a   Lu, Yongju ^a   Wu, Kai ^a   Thakur, Chitra ^a   Chang, Qingshan ^a   Sun, Jiaying ^a   Chen, Fei ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

Akt; Arsenic; Cytoplasmic translocation; EZH2; Oxidative stress; Phosphorylation

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; ARSENIC; HYDROGEN PEROXIDE; MYC PROTEIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STAT3 PROTEIN; TRANSCRIPTION FACTOR EZH2;

ANTIOXIDANT ACTIVITY; ARTICLE; CANCER CELL; CELLULAR STRESS SIGNAL; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; LUNG ALVEOLUS EPITHELIUM; LUNG CANCER; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AKT; ARSENIC; CYTOPLASMIC TRANSLOCATION; EZH2; OXIDATIVE STRESS; PHOSPHORYLATION;

ARSENIC; BRONCHI; CELLS, CULTURED; EPITHELIAL CELLS; HUMANS; LUNG NEOPLASMS; PHOSPHORYLATION; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; RIBOSOMAL PROTEINS;

EID: 84897528130     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2014.02.005     Document Type: Article

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