Enzymatic production of α-ketoglutaric acid from l-glutamic acid via l-glutamate oxidase

Journal of Biotechnology

Volumn 179, Issue 1, 2014, Pages 56-62

  Niu, Panqing ^a   Dong, Xiaoxiang ^a   Wang, Yuancai ^a   Liu, Liming ^a  

^a JIANGNAN UNIVERSITY   (China)

Author keywords

Biocatalyst; Catalase; Fermentation optimization; Recombinant LGOX

Indexed keywords

BIOCATALYSTS; ESCHERICHIA COLI;

CATALASE; ENZYMATIC PRODUCTION; ESCHERICHIA COLI BL21; FERMENTATION OPTIMIZATIONS; L-GLUTAMATE OXIDASE; OPTIMUM CONDITIONS; RECOMBINANT LGOX; STRUCTURE CHARACTERISTIC;

AMINO ACIDS;

2 OXOGLUTARIC ACID; CATALASE; DNA FRAGMENT; GLUTAMIC ACID; L GLUTAMATE OXIDASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG; ALPHA-KETOGLUTARIC ACID; BACTERIAL PROTEIN; L-GLUTAMATE OXIDASE; RECOMBINANT PROTEIN;

AFFINITY CHROMATOGRAPHY; ARTICLE; CHEMICAL STRUCTURE; COMPETITIVE INHIBITION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME PURIFICATION; ENZYME SPECIFICITY; ENZYME STABILITY; ENZYME SYNTHESIS; ESCHERICHIA COLI; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; CHEMICAL MODEL; CHEMISTRY; CLASSIFICATION; ENZYMOLOGY; GENETICS; METABOLISM; PH; STREPTOMYCES; TEMPERATURE;

AMINO ACID OXIDOREDUCTASES; BACTERIAL PROTEINS; GLUTAMIC ACID; HYDROGEN-ION CONCENTRATION; KETOGLUTARIC ACIDS; MODELS, CHEMICAL; RECOMBINANT PROTEINS; STREPTOMYCES; TEMPERATURE;

EID: 84897509255     PISSN: 01681656     EISSN: 18734863     Source Type: Journal    
DOI: 10.1016/j.jbiotec.2014.03.021     Document Type: Article

References (31)

1. Allain C.C., Poon L.S., Chan C.S., Richmond W., Fu P.C. Enzymatic determination of total serum cholesterol. Clin. Chem. 1974, 20:470-475.
2. Arima J., Sasaki C., Sakaguchi C., Mizuno H., Tamura T., Kashima A., Kusakabe H., Sugio S., Inagaki K. Structural characterization of l-glutamate oxidase from Streptomyces sp X-119-6. Febs J. 2009, 276:4318-4327.
3. Arima J., Tamura T., Kusakabe H., Ashiuchi M., Yagi T., Tanaka H., Inagaki K. Recombinant expression, biochemical characterization and stabilization through proteolysis of an l-glutamate oxidase from Streptomyces sp X-119-6. J. Biochem. 2003, 134:805-812.
4. Barrett D.G., Yousaf M.N. Poly(triol alpha-ketoglutarate) as biodegradable, chemoselective, and mechanically tunable elastomers. Macromolecules 2008, 41:6347-6352.
5. Bohmer A., Muller A., Passarge M., Liebs P., Honeck H., Muller H.G. A novel l-glutamate oxidase from Streptomyces endus. Purification and properties. Eur. J. Biochem./FEBS 1989, 182:327-332.
6. Bornscheuer U.T., Huisman G.W., Kazlauskas R.J., Lutz S., Moore J.C., Robins K. Engineering the third wave of biocatalysis. Nature 2012, 485:185-194.
7. Chernyavskaya O.G., Shishkanova N.V., Il'chenko A.P., Finogenova T.V. Synthesis of alpha-ketoglutaric acid by Yarrowia lipolytica yeast grown on ethanol. Appl. Microbiol. Biot. 2000, 53:152-158.
8. Gopal G.J., Kumar A. Strategies for the production of recombinant protein in Escherichia coli. Protein J. 2013, 32:419-425.
9. Hossain G.S., Li J., Shin H.-d., Chen R.R., Du G., Liu L., Chen J. Bioconversion of l-glutamic acid to α-ketoglutaric acid by an immobilized whole-cell biocatalyst expressing l-amino acid deaminase from Proteus mirabilisi. J. Biotechnol. 2014, 169:112-120.
10. 2 on viscosity of culture broth, and on activities of enzymes around the 2-oxoglutarate branch, in Bacillus subtilis CGMCC 2108 producing poly-(gamma-glutamic acid). Bioresour. Technol. 2011, 102:3595-3598.
11. Kamei T., Asano K., Kondo H., Matsuzaki M., Nakamura S. l-Glutamate oxidase from Streptomyces violascens. I. Properties. Chem. Pharm. Bull. 1983, 31:1307-1314.
12. Kamei T., Asano K., Kondo H., Matsuzaki M., Nakamura S. l-Glutamate oxidase from Streptomyces violascens. Properties. Chem. Pharm. Bull. 1983, 31:8.
13. Komatsuzaki N., Shima J., Kawamoto S., Momose H., Kimura T. Production of gamma-aminobutyric acid (GABA) by Lactobacillus paracasei isolated from traditional fermented foods. Food Microbiol. 2005, 22:497-504.
14. Kommoju P.R., Macheroux P., Ghisla S. Molecular cloning, expression and purification of l-amino acid oxidase from the Malayan pit viper Calloselasma rhodostoma. Protein Express Purif. 2007, 52:89-95.
15. Liu L., Hossain G.S., Shin H.D., Li J.H., Du G.C., Chen J. One-step production of alpha-ketoglutaric acid from glutamic acid with an engineered l-amino acid deaminase from Proteus mirabilis. J. Biotechnol. 2013, 164:97-104.
16. Liu L., Li Y., Zhu Y., Du G., Chen J. Redistribution of carbon flux in Torulopsis glabrata by altering vitamin and calcium level. Metab. Eng. 2007, 9:21-29.
17. Maldonado P., Desmarquest J.-P., Gaillardin C., Binet D. Yeasts 1976, US Patents.
18. Odman P., Wellborn W.B., Bommarius A.S. An enzymatic process to alpha-ketoglutarate from l-glutamate: the coupled system l-glutamate dehydrogenase/NADH oxidase. Tetrahedron Asymmetr. 2004, 15:2933-2937.
19. Otto C., Yovkova V., Aurich A., Mauersberger S., Barth G. Variation of the by-product spectrum during α-ketoglutaric acid production from raw glycerol by overexpression of fumarase and pyruvate carboxylase genes in Yarrowia lipolytica. Appl. Microbiol. Biotechnol. 2012, 95:905-917.
20. Otto C., Yovkova V., Barth G. Overproduction and secretion of alpha-ketoglutaric acid by microorganisms. Appl. Microbiol. Biotechnol. 2011, 92:689-695.
21. Riethorst W., Reichert A. An industrial view on enzymes for the cleavage of cephalosporin C. Chimia 1999, 53:600-607.
22. Sukhacheva M.V., Netrusov A.I. Streptomyces sp Z-11-6, a novel producer of extracellular l-glutamate oxidase. Microbiology+ 2000, 69:13-16.
23. Tan Q., Song Q., Zhang Y., Wei D. Characterization and application of D-amino acid oxidase and catalase within permeabilized Pichia pastoris cells in bioconversions. Appl. Biochem. Biotech. 2007, 136:279-289.
24. Upadhyay S., Ohgami N., Kusakabe H., Mizuno H., Arima J., Tamura T., Inagaki K., Suzuki H. Performance characterization of recombinant l-glutamate oxidase in a micro GOT/GPT sensing system. Sensor Actuat. B-Chem. 2006, 119:570-576.
25. Wachiratianchai S., Bhumiratana A., Udomsopagit S. Isolation, purification, and characterization of l-glutamate oxidase from Streptomyces sp 18G. Electron J. Biotech. 2004, 7.
26. Yamamoto S., Wakayama M., Tachiki T. Cloning and expression of Methylovorus mays No. 9 gene encoding gamma-glutamylmethylamide synthetase: an enzyme usable in theanine formation by coupling with the alcoholic fermentation system of baker's yeast. Biosci. Biotech. Bioch. 2008, 72:101-109.
27. Yovkova V., Otto C., Aurich A., Mauersberger S., Barth G. Engineering the α-ketoglutarate overproduction from raw glycerol by overexpression of the genes encoding NADH+-dependent isocitrate dehydrogenase and pyruvate carboxylase in Yarrowia lipolytica. Appl. Microbiol. Biotechnol. 2013.
28. Yu Z.Z., Du G.G., Zhou J.W., Chen J. Enhanced alpha-ketoglutaric acid production in Yarrowia lipolytica WSH-Z06 by an improved integrated fed-batch strategy. Bioresour. Technol. 2012, 114:597-602.
29. Zhang D., Shi Z., Liu L., Chen J., Du G. Enhancement of α-ketoglutarate production in Torulopsis glabrata: redistribution of carbon flux from pyruvate to α-ketoglutarate. Biotechnol. Bioproc. E 2009, 14:134-139.
30. Zhou J., Yin X., Madzak C., Du G., Chen J. Enhanced alpha-ketoglutarate production in Yarrowia lipolytica WSH-Z06 by alteration of the acetyl-CoA metabolism. J. Biotechnol. 2012, 161:257-264.
31. Zhou J.W., Zhou H.Y., Du G.C., Liu L.M., Chen J.A. Screening of a thiamine-auxotrophic yeast for alpha-ketoglutaric acid overproduction. Lett. Appl. Microbiol. 2010, 51:264-271.