-
1
-
-
0041671071
-
QSulf1 remodels the 6-O sulfation states of cell surface proteoglycans to promote Wnt signaling
-
Ai, X., Do, A. T., Lozynska, O., Kusche-Gullberg, M., Lindhal, U., and Emerson, C. P. (2003). QSulf1 remodels the 6-O sulfation states of cell surface proteoglycans to promote Wnt signaling. J Cell Biol 162, 341-351.
-
(2003)
J Cell Biol
, vol.162
, pp. 341-351
-
-
Ai, X.1
Do, A.T.2
Lozynska, O.3
Kusche-Gullberg, M.4
Lindhal, U.5
Emerson, C.P.6
-
2
-
-
38149063860
-
Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells
-
Aikawa, T., Whipple, C. A., Lopez, M. E., et al. (2008). Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells. J Clin Invest 118, 89-99.
-
(2008)
J Clin Invest
, vol.118
, pp. 89-99
-
-
Aikawa, T.1
Whipple, C.A.2
Lopez, M.E.3
-
3
-
-
37349070126
-
Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface
-
Akiyama, T., Kamimura, K., Firkus, C., Takeo, S., Shimmi, O., and Nakato, H. (2008). Dally regulates Dpp morphogen gradient formation by stabilizing Dpp on the cell surface. Dev Biol 313, 408-419.
-
(2008)
Dev Biol
, vol.313
, pp. 408-419
-
-
Akiyama, T.1
Kamimura, K.2
Firkus, C.3
Takeo, S.4
Shimmi, O.5
Nakato, H.6
-
4
-
-
77951896697
-
The long-range activity of hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum
-
Ayers, K. L., Gallet, A., Staccini-Lavenant, L., and Therond, P. P. (2010). The long-range activity of hedgehog is regulated in the apical extracellular space by the glypican Dally and the hydrolase Notum. Dev Cell 18, 605-620.
-
(2010)
Dev Cell
, vol.18
, pp. 605-620
-
-
Ayers, K.L.1
Gallet, A.2
Staccini-Lavenant, L.3
Therond, P.P.4
-
5
-
-
5444233782
-
Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans
-
Belenkaya, T. Y., Han, C., Yan, D., et al. (2004). Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans. Cell 119, 231-244.
-
(2004)
Cell
, vol.119
, pp. 231-244
-
-
Belenkaya, T.Y.1
Han, C.2
Yan, D.3
-
6
-
-
34247610845
-
Heparan sulphate proteoglycans fine-tune mammalian physiology
-
Bishop, J. R., Schuksz, M., and Esko, J. D. (2007). Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature 446, 1030-1036.
-
(2007)
Nature
, vol.446
, pp. 1030-1036
-
-
Bishop, J.R.1
Schuksz, M.2
Esko, J.D.3
-
7
-
-
79952231921
-
Management of hepatocellular carcinoma: An update
-
Bruix, J., and Sherman, M. (2011). Management of hepatocellular carcinoma: an update. Hepatology 53, 1020-1022.
-
(2011)
Hepatology
, vol.53
, pp. 1020-1022
-
-
Bruix, J.1
Sherman, M.2
-
8
-
-
66449083531
-
Mutations in the heparan-sulfate proteoglycan glypican-6 (GPC6) impair endochodral ossification and cause recessive omodysplasia
-
Campos-Xavier, A. B., Martinet, D., Bateman, J., et al. (2009). Mutations in the heparan-sulfate proteoglycan glypican-6 (GPC6) impair endochodral ossification and cause recessive omodysplasia. Am J Hum Genet 84, 760-770.
-
(2009)
Am J Hum Genet
, vol.84
, pp. 760-770
-
-
Campos-Xavier, A.B.1
Martinet, D.2
Bateman, J.3
-
9
-
-
0033549528
-
Glypican-3-deficient mice exhibit the overgrowth and renal abnormalities typical of the Simpson-Golabi-Behmel syndrome
-
Cano-Gauci, D. F., Song, H. H., Yang, H., et al. (1999). Glypican-3-deficient mice exhibit the overgrowth and renal abnormalities typical of the Simpson-Golabi-Behmel syndrome. J Cell Biol 146, 255-264.
-
(1999)
J Cell Biol
, vol.146
, pp. 255-264
-
-
Cano-Gauci, D.F.1
Song, H.H.2
Yang, H.3
-
10
-
-
0038786861
-
Glypican-3: A novel serum and histochemical marker for hepatocellular carcinoma
-
Capurro, M., Wanless, I. R., Sherman, M., et al. (2003). Glypican-3: a novel serum and histochemical marker for hepatocellular carcinoma. Gastroenterology 125, 81-90.
-
(2003)
Gastroenterology
, vol.125
, pp. 81-90
-
-
Capurro, M.1
Wanless, I.R.2
Sherman, M.3
-
11
-
-
22244480967
-
Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling
-
Capurro, M., Xiang, Y. Y., Lobe, C., and Filmus, J. (2005a). Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling. Cancer Res 65, 6245-6254.
-
(2005)
Cancer Res
, vol.65
, pp. 6245-6254
-
-
Capurro, M.1
Xiang, Y.Y.2
Lobe, C.3
Filmus, J.4
-
12
-
-
68249107640
-
Overgrowth of a mouse model of Simpson-Golabi-Behmel syndrome is partly mediated by Indian Hedgehog
-
Capurro, M. I., Li, F., and Filmus, J. (2009). Overgrowth of a mouse model of Simpson-Golabi-Behmel syndrome is partly mediated by Indian Hedgehog. EMBO Rep 10, 901-907.
-
(2009)
EMBO Rep
, vol.10
, pp. 901-907
-
-
Capurro, M.I.1
Li, F.2
Filmus, J.3
-
13
-
-
29244465513
-
Processing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma
-
Capurro, M. I., Shi, W., Sandal, S., and Filmus, J. (2005b). Processing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma. J Biol Chem 280, 41201-41206.
-
(2005)
J Biol Chem
, vol.280
, pp. 41201-41206
-
-
Capurro, M.I.1
Shi, W.2
Sandal, S.3
Filmus, J.4
-
14
-
-
43049097898
-
Glypican-3 inhibits hedgehog signaling during development by competing with Patched for Hedgehog binding
-
Capurro, M. I., Xu, P., Shi, W., Li, F., Jia, A., and Filmus, J. (2008). Glypican-3 inhibits hedgehog signaling during development by competing with Patched for Hedgehog binding. Dev Cell 14, 700-711.
-
(2008)
Dev Cell
, vol.14
, pp. 700-711
-
-
Capurro, M.I.1
Xu, P.2
Shi, W.3
Li, F.4
Jia, A.5
Filmus, J.6
-
16
-
-
0035715062
-
Simpson Golabi Behmel syndrome: Progress toward understanding the molecular basis for overgrowth, malformation, and cancer predisposition
-
DeBaun, M. R., Ess, J., and Saunders, S. (2001). Simpson Golabi Behmel syndrome: progress toward understanding the molecular basis for overgrowth, malformation, and cancer predisposition. Mol Genet Metab 72, 279-286.
-
(2001)
Mol Genet Metab
, vol.72
, pp. 279-286
-
-
DeBaun, M.R.1
Ess, J.2
Saunders, S.3
-
17
-
-
0242593885
-
Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movements
-
De Cat, B., Muyldermans, S. Y., Coomans, C., et al. (2003). Processing by proprotein convertases is required for glypican-3 modulation of cell survival, Wnt signaling, and gastrulation movements. J Cell Biol 163, 625-635.
-
(2003)
J Cell Biol
, vol.163
, pp. 625-635
-
-
De Cat, B.1
Muyldermans, S.Y.2
Coomans, C.3
-
18
-
-
79955748614
-
Novel contactdependent bone morphogenetic protein (BMP) signaling mediated by heparan sulfate proteoglycans
-
Dejima, K., Kanai, M. I., Akiyama, T., Levings, D. C., and Nakato, H. (2011). Novel contactdependent bone morphogenetic protein (BMP) signaling mediated by heparan sulfate proteoglycans. J Biol Chem 286, 17103-17111.
-
(2011)
J Biol Chem
, vol.286
, pp. 17103-17111
-
-
Dejima, K.1
Kanai, M.I.2
Akiyama, T.3
Levings, D.C.4
Nakato, H.5
-
19
-
-
0346258165
-
The glypican Dally-like is required for hedgehog signalling in the embryonic epidermis of Drosophila
-
Desbordes, S. C., and Sanson, B. (2003). The glypican Dally-like is required for hedgehog signalling in the embryonic epidermis of Drosophila. Development 130, 6245-6255.
-
(2003)
Development
, vol.130
, pp. 6245-6255
-
-
Desbordes, S.C.1
Sanson, B.2
-
20
-
-
61749103943
-
The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma
-
Di Tommaso, L., Destro, A., Seok, J. Y., et al. (2009). The application of markers (HSP70 GPC3 and GS) in liver biopsies is useful for detection of hepatocellular carcinoma. J Hepatol 50, 746-754.
-
(2009)
J Hepatol
, vol.50
, pp. 746-754
-
-
Di Tommaso, L.1
Destro, A.2
Seok, J.Y.3
-
21
-
-
34250870665
-
Lipoprotein-heparan sulfate interactions in the Hh pathway
-
Eugster, C., Panakova, D., Mahmoud, A., and Eaton, S. (2007). Lipoprotein-heparan sulfate interactions in the Hh pathway. Dev Cell 13, 57-71.
-
(2007)
Dev Cell
, vol.13
, pp. 57-71
-
-
Eugster, C.1
Panakova, D.2
Mahmoud, A.3
Eaton, S.4
-
22
-
-
79952470622
-
Recombinant soluble glypican 3 protein inhibits the growth of hepatocellular carcinoma in vitro
-
Feng, M., Kim, H., and Ho, M. (2011). Recombinant soluble glypican 3 protein inhibits the growth of hepatocellular carcinoma in vitro. Int J Cancer 128, 2246-2247.
-
(2011)
Int J Cancer
, vol.128
, pp. 2246-2247
-
-
Feng, M.1
Kim, H.2
Ho, M.3
-
23
-
-
66249084507
-
Glypicans
-
Filmus, J., Capurro, M., and Rast, J. (2008). Glypicans. Genome Biol 9, 224.
-
(2008)
Genome Biol
, vol.9
, pp. 224
-
-
Filmus, J.1
Capurro, M.2
Rast, J.3
-
24
-
-
14844360345
-
Glypicans shunt the wingless signal between local signalling and further transport
-
Franch-Marro, X., Marchand, O., Piddini, E., Ricardo, S., Alexandre, C., and Vincent, J. P. (2005). Glypicans shunt the wingless signal between local signalling and further transport. Development 132, 659-666.
-
(2005)
Development
, vol.132
, pp. 659-666
-
-
Franch-Marro, X.1
Marchand, O.2
Piddini, E.3
Ricardo, S.4
Alexandre, C.5
Vincent, J.P.6
-
25
-
-
0038067867
-
Dally regulates Dpp morphogen gradient formation in the Drosophila wing
-
Fujise, M., Takeo, S., Kamimura, K., et al. (2003). Dally regulates Dpp morphogen gradient formation in the Drosophila wing. Development 130, 1515-1522.
-
(2003)
Development
, vol.130
, pp. 1515-1522
-
-
Fujise, M.1
Takeo, S.2
Kamimura, K.3
-
26
-
-
43049138477
-
Cellular trafficking of the glypian Dally-like is required for full-strength hedgehog signaling and wingless transcytosis
-
Gallet, A., Staccini-Lavenant, L., and Therond, P. P. (2008). Cellular trafficking of the glypian Dally-like is required for full-strength hedgehog signaling and wingless transcytosis. Dev Cell 14, 712-725.
-
(2008)
Dev Cell
, vol.14
, pp. 712-725
-
-
Gallet, A.1
Staccini-Lavenant, L.2
Therond, P.P.3
-
27
-
-
70350166294
-
The glypican Dally is required in the niche for the maintenance of germline stem cells and short-range BMP signaling in the Drosophila ovary
-
Guo, Z., and Wang, Z. (2009). The glypican Dally is required in the niche for the maintenance of germline stem cells and short-range BMP signaling in the Drosophila ovary. Development 136, 3627-3635.
-
(2009)
Development
, vol.136
, pp. 3627-3635
-
-
Guo, Z.1
Wang, Z.2
-
28
-
-
77949381392
-
A novel mechanism of sequestering FGF-2 by glypican in lipid rafts, allowing skeletal muscle differentiation
-
Gutierrez, J., and Brandan, E. (2010). A novel mechanism of sequestering FGF-2 by glypican in lipid rafts, allowing skeletal muscle differentiation. Mol Cell Biol 30, 1634-1649.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 1634-1649
-
-
Gutierrez, J.1
Brandan, E.2
-
29
-
-
21844440822
-
Glyican-3 modulates inhibitory Bmp2-Smad signaling to control renal development in vivo
-
Hartwig, S., Hu, M. C., Cella, C., Piscione, T., Filmus, J., and Rosenblum, N. D. (2005). Glyican-3 modulates inhibitory Bmp2-Smad signaling to control renal development in vivo. Mech Dev 122, 928-938.
-
(2005)
Mech Dev
, vol.122
, pp. 928-938
-
-
Hartwig, S.1
Hu, M.C.2
Cella, C.3
Piscione, T.4
Filmus, J.5
Rosenblum, N.D.6
-
30
-
-
73349086253
-
Drosophila glypicans regulate the germline stem cell niche
-
Hayashi, Y., Kobayashi, S., and Nakato, H. (2009). Drosophila glypicans regulate the germline stem cell niche. J Cell Biol 187, 473-480.
-
(2009)
J Cell Biol
, vol.187
, pp. 473-480
-
-
Hayashi, Y.1
Kobayashi, S.2
Nakato, H.3
-
31
-
-
11144357785
-
Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma
-
Hippo, Y., Watanabe, K., Watanabe, A., et al. (2004). Identification of soluble NH2-terminal fragment of glypican-3 as a serological marker for early-stage hepatocellular carcinoma. Cancer Res 64, 2418-2423.
-
(2004)
Cancer Res
, vol.64
, pp. 2418-2423
-
-
Hippo, Y.1
Watanabe, K.2
Watanabe, A.3
-
32
-
-
79251599238
-
Glypican-3: A new target for cancer immunotherapy
-
Ho, M., and Kim, H. (2010). Glypican-3: a new target for cancer immunotherapy. Eur J Cancer 47, 333-338.
-
(2010)
Eur J Cancer
, vol.47
, pp. 333-338
-
-
Ho, M.1
Kim, H.2
-
33
-
-
0030663283
-
Cloning and expression of a developmentally regulated transcript MXR7 in hepatocellular carcinoma: Biological significance and temorospatial distribution
-
Hsu, H. C., Cheng, W., and Lai, P. L. (1997). Cloning and expression of a developmentally regulated transcript MXR7 in hepatocellular carcinoma: biological significance and temorospatial distribution. Cancer Res 57, 5179-5184.
-
(1997)
Cancer Res
, vol.57
, pp. 5179-5184
-
-
Hsu, H.C.1
Cheng, W.2
Lai, P.L.3
-
34
-
-
57149085273
-
Anti-glypican-3 antibody as a potential antitumor agent for human liver cancer
-
Ishiguro, T., Sugimoto, M., Kinoshita, Y., et al. (2008). Anti-glypican-3 antibody as a potential antitumor agent for human liver cancer. Cancer Res 68, 9832-9838.
-
(2008)
Cancer Res
, vol.68
, pp. 9832-9838
-
-
Ishiguro, T.1
Sugimoto, M.2
Kinoshita, Y.3
-
35
-
-
0030831119
-
Dally, a Drosophila glypican, controls celular responses to the TGF-beta-related morphogen Dpp
-
Jackson, S. M., Nakato, H., Sugiura, M., et al. (1997). Dally, a Drosophila glypican, controls celular responses to the TGF-beta-related morphogen Dpp. Development 124, 4113-4120.
-
(1997)
Development
, vol.124
, pp. 4113-4120
-
-
Jackson, S.M.1
Nakato, H.2
Sugiura, M.3
-
36
-
-
70349410388
-
Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis
-
Jen, Y. H. L., Musacchio, M., and Lander, A. D. (2009). Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis. Neural Dev 4, 33.
-
(2009)
Neural Dev
, vol.4
, pp. 33
-
-
Jen, Y.H.L.1
Musacchio, M.2
Lander, A.D.3
-
37
-
-
32344447373
-
The HSPGs syndecan and Dallylike bind the receptor phophatase LAR and exert distinct effects on synaptic development
-
Johnson, K. G., Tenney, A. P., Ghose, A., et al. (2006). The HSPGs syndecan and Dallylike bind the receptor phophatase LAR and exert distinct effects on synaptic development. Neuron 49, 517-531.
-
(2006)
Neuron
, vol.49
, pp. 517-531
-
-
Johnson, K.G.1
Tenney, A.P.2
Ghose, A.3
-
38
-
-
80051991015
-
Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling
-
Kim, M. S., Saunders, A. M., Hamaoka, B., et al. (2011). Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling. Porc. Natl. Acad. Sci. U.S.A. 108, 13112-13117.
-
(2011)
Porc. Natl. Acad. Sci. U.S.A
, vol.108
, pp. 13112-13117
-
-
Kim, M.S.1
Saunders, A.M.2
Hamaoka, B.3
-
39
-
-
0032213027
-
The cell surface heparan sulfate proteoglycan glypican-1 regulates growth factor in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer
-
Kleeff, J., Ishiwata, T., Kumbasar, A., et al. (1998). The cell surface heparan sulfate proteoglycan glypican-1 regulates growth factor in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer. J Clin Invest 102, 1662-1673.
-
(1998)
J Clin Invest
, vol.102
, pp. 1662-1673
-
-
Kleeff, J.1
Ishiwata, T.2
Kumbasar, A.3
-
40
-
-
33646721733
-
Identification of HLA-A2- or HLA-A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy of hepatocellular carcinoma
-
Komori, H., Nakatsura, T., Senju, S., et al. (2006). Identification of HLA-A2- or HLA-A24-restricted CTL epitopes possibly useful for glypican-3-specific immunotherapy of hepatocellular carcinoma. Clin Cancer Res 12, 2689-2697.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 2689-2697
-
-
Komori, H.1
Nakatsura, T.2
Senju, S.3
-
41
-
-
5044249440
-
Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity
-
Kreuger, J., Perez, L., Giraldez, A. J., and Cohen, S. M. (2004). Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity. Dev Cell 7, 503-512.
-
(2004)
Dev Cell
, vol.7
, pp. 503-512
-
-
Kreuger, J.1
Perez, L.2
Giraldez, A.J.3
Cohen, S.M.4
-
42
-
-
79951869901
-
Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signaling
-
Li, F., Shi, W., Capurro, M., and Filmus, J. (2011). Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signaling. J Cell Biol 192, 691-704.
-
(2011)
J Cell Biol
, vol.192
, pp. 691-704
-
-
Li, F.1
Shi, W.2
Capurro, M.3
Filmus, J.4
-
43
-
-
33750430854
-
Glypican-3 expression distinguishes small hepatocellular carcinomas from cirrhosis, dysplastic nodules, and focal nodular hyperplasia-like nodules
-
Libbrecht, L., Severi, T., Cassiman, D., et al. (2006). Glypican-3 expression distinguishes small hepatocellular carcinomas from cirrhosis, dysplastic nodules, and focal nodular hyperplasia-like nodules. Am J Surg Pathol 30, 1405-1411.
-
(2006)
Am J Surg Pathol
, vol.30
, pp. 1405-1411
-
-
Libbrecht, L.1
Severi, T.2
Cassiman, D.3
-
44
-
-
0033566126
-
Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signaling
-
Lin, X., and Perrimon, N. (1999). Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signaling. Nature 400, 281-284.
-
(1999)
Nature
, vol.400
, pp. 281-284
-
-
Lin, X.1
Perrimon, N.2
-
45
-
-
0037470952
-
Identification of hedgehog pathway components by RNAi in Drosophila cultured cells
-
Lum, L., Yao, S., Mozer, B., et al. (2003). Identification of hedgehog pathway components by RNAi in Drosophila cultured cells. Science 299, 2039-2045.
-
(2003)
Science
, vol.299
, pp. 2039-2045
-
-
Lum, L.1
Yao, S.2
Mozer, B.3
-
46
-
-
33750613935
-
Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas
-
Luo, J. H., Ren, B., Keryanov, S., et al. (2006). Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas. Hepatology 44, 1012-1024.
-
(2006)
Hepatology
, vol.44
, pp. 1012-1024
-
-
Luo, J.H.1
Ren, B.2
Keryanov, S.3
-
47
-
-
0038054270
-
Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker
-
Nakatsura, T., Yoshitake, Y., Senju, S., et al. (2003). Glypican-3, overexpressed specifically in human hepatocellular carcinoma, is a novel tumor marker. Biochem Biophys Res Commun 306, 16-25.
-
(2003)
Biochem Biophys Res Commun
, vol.306
, pp. 16-25
-
-
Nakatsura, T.1
Yoshitake, Y.2
Senju, S.3
-
48
-
-
0032475859
-
Clinical and molecular aspects of the Simpson-Golabi-Behmel syndrome
-
Neri, G., Gurrieri, F., Zanni, G., and Lin, A. (1998). Clinical and molecular aspects of the Simpson-Golabi-Behmel syndrome. Am J Med Genet 79, 279-283.
-
(1998)
Am J Med Genet
, vol.79
, pp. 279-283
-
-
Neri, G.1
Gurrieri, F.2
Zanni, G.3
Lin, A.4
-
49
-
-
70349786507
-
Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development
-
Ng, A., Wong, M., Viviano, B., et al. (2009). Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development. Dev Biol 335, 208-215.
-
(2009)
Dev Biol
, vol.335
, pp. 208-215
-
-
Ng, A.1
Wong, M.2
Viviano, B.3
-
50
-
-
0038750629
-
Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis
-
Ohkawara, B., Yamamoto, T. S., Tada, M., and Ueno, N. (2003). Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis. Development 130, 2129-2138.
-
(2003)
Development
, vol.130
, pp. 2129-2138
-
-
Ohkawara, B.1
Yamamoto, T.S.2
Tada, M.3
Ueno, N.4
-
51
-
-
79955465968
-
Common variation in GPC5 is associated with acquired nephrotic syndrome
-
Okamoto, K., Tokunaga, K., Doi, K., et al. (2011). Common variation in GPC5 is associated with acquired nephrotic syndrome. Nat Genet 43, 459-463.
-
(2011)
Nat Genet
, vol.43
, pp. 459-463
-
-
Okamoto, K.1
Tokunaga, K.2
Doi, K.3
-
52
-
-
0034284766
-
Gly-pican-3 controls cellular responses to Bmp4 in limb patterning and skeletal development
-
Paine-Saunders, S., Viviano, B. L., Zupicich, J., Skarnes, W. C., and Saunders, S. (2000). Gly-pican-3 controls cellular responses to Bmp4 in limb patterning and skeletal development. Dev Biol 225, 179-187.
-
(2000)
Dev Biol
, vol.225
, pp. 179-187
-
-
Paine-Saunders, S.1
Viviano, B.L.2
Zupicich, J.3
Skarnes, W.C.4
Saunders, S.5
-
53
-
-
20444475795
-
An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma
-
Patil, M. A., Chua, M. S., Pan, K. H., et al. (2005). An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinoma. Oncogene 24, 3737-3747.
-
(2005)
Oncogene
, vol.24
, pp. 3737-3747
-
-
Patil, M.A.1
Chua, M.S.2
Pan, K.H.3
-
54
-
-
13344261391
-
Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome
-
Pilia, G., Hughes-Benzie, R. M., MacKenzie, A., et al. (1996). Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome. Nat Genet 12, 241-247.
-
(1996)
Nat Genet
, vol.12
, pp. 241-247
-
-
Pilia, G.1
Hughes-Benzie, R.M.2
MacKenzie, A.3
-
55
-
-
18844453426
-
The heparan sulfate proteoglycans Dally-like and Syndecan have distinct functions in axon guidance and visual-system assembly in Drosophila
-
Rawson, J. M., Dimitroff, B., Johnson, K. G., et al. (2005). The heparan sulfate proteoglycans Dally-like and Syndecan have distinct functions in axon guidance and visual-system assembly in Drosophila. Curr Biol 15, 833-838.
-
(2005)
Curr Biol
, vol.15
, pp. 833-838
-
-
Rawson, J.M.1
Dimitroff, B.2
Johnson, K.G.3
-
56
-
-
0031259923
-
Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain
-
Saunders, S., Paine-Saunders, S., and Lander, A. D. (1997). Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain. Dev Biol 190, 78-93.
-
(1997)
Dev Biol
, vol.190
, pp. 78-93
-
-
Saunders, S.1
Paine-Saunders, S.2
Lander, A.D.3
-
57
-
-
69549111677
-
Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent eeextension in vertebrate embryos
-
Shao, M., Liu, Z. Z., Wang, C. D., et al. (2009). Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent eeextension in vertebrate embryos. Development 136, 2121-2131.
-
(2009)
Development
, vol.136
, pp. 2121-2131
-
-
Shao, M.1
Liu, Z.Z.2
Wang, C.D.3
-
58
-
-
78149409998
-
Altering glypican-1 levels modulates canonical Wnt signaling during trigeminal placode development
-
Shiba, K., Hu, N., and Bronner-Fraser, M. (2010). Altering glypican-1 levels modulates canonical Wnt signaling during trigeminal placode development. Dev Biol 348, 107-118.
-
(2010)
Dev Biol
, vol.348
, pp. 107-118
-
-
Shiba, K.1
Hu, N.2
Bronner-Fraser, M.3
-
59
-
-
79958708835
-
Heparan sulfate proteoglycan specificity during axon pathway formation in Drosophila embryo
-
Smart, A. D., Course, M. M., Rawson, J., Selleck, S. B., Van Vactor, D., and Johnson, K. G. (2011). Heparan sulfate proteoglycan specificity during axon pathway formation in Drosophila embryo. Dev Neurobiol 71, 608-618.
-
(2011)
Dev Neurobiol
, vol.71
, pp. 608-618
-
-
Smart, A.D.1
Course, M.M.2
Rawson, J.3
Selleck, S.B.4
Van Vactor, D.5
Johnson, K.G.6
-
60
-
-
0037137489
-
The role of glypicans in mammalian development
-
Song, H. H., and Filmus, J. (2002). The role of glypicans in mammalian development. Biochim Biophys Acta 1573, 241-246.
-
(2002)
Biochim Biophys Acta
, vol.1573
, pp. 241-246
-
-
Song, H.H.1
Filmus, J.2
-
61
-
-
12544251542
-
The loss of glypican-3 induces alterations in Wnt signaling
-
Song, H. H., Shi, W., Xiang, Y., and Filmus, J. (2005). The loss of glypican-3 induces alterations in Wnt signaling. J Biol Chem 280, 2116-2125.
-
(2005)
J Biol Chem
, vol.280
, pp. 2116-2125
-
-
Song, H.H.1
Shi, W.2
Xiang, Y.3
Filmus, J.4
-
62
-
-
33744729372
-
Glypican-1 is frequently overexpressed in human gliomas and enhances FGF-2 signaling in glioma cells
-
Su, G., Meyer, K., Nandini, C. D., Qiao, D., Salamat, S., and Friedl, A. (2006). Glypican-1 is frequently overexpressed in human gliomas and enhances FGF-2 signaling in glioma cells. Am J Pathol 168, 2014-2026.
-
(2006)
Am J Pathol
, vol.168
, pp. 2014-2026
-
-
Su, G.1
Meyer, K.2
Nandini, C.D.3
Qiao, D.4
Salamat, S.5
Friedl, A.6
-
63
-
-
84859986516
-
Crystal structure of N-glycosylated human glypican-1 core protein
-
Svensson, G., Awad, W., Hakansson, M., Mani, K., and Logan, D. T. (2012). Crystal structure of N-glycosylated human glypican-1 core protein. J Biol Chem 287, 14040-14051.
-
(2012)
J Biol Chem
, vol.287
, pp. 14040-14051
-
-
Svensson, G.1
Awad, W.2
Hakansson, M.3
Mani, K.4
Logan, D.T.5
-
64
-
-
73549083896
-
Glypican-1 mediates both prion protein lipid raft association and disease isoform formation
-
Taylor, D. R., Whitehouse, I. J., and Hooper, N. M. (2009). Glypican-1 mediates both prion protein lipid raft association and disease isoform formation. PLOS Pathog 5, e1000666.
-
(2009)
PLOS Pathog
, vol.5
, pp. e1000666
-
-
Taylor, D.R.1
Whitehouse, I.J.2
Hooper, N.M.3
-
65
-
-
0035434453
-
The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension
-
Topczewsky, J., Sepich, D. S., Myers, D. C., et al. (2001). The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension. Dev Cell 1, 251-264.
-
(2001)
Dev Cell
, vol.1
, pp. 251-264
-
-
Topczewsky, J.1
Sepich, D.S.2
Myers, D.C.3
-
66
-
-
0033566085
-
The cell-surface proteoglycan Dally regulates Wingless signaling in Drosophila
-
Tsuda, M., Kamimura, K., Nakato, H., et al. (1999). The cell-surface proteoglycan Dally regulates Wingless signaling in Drosophila. Nature 400, 276-280.
-
(1999)
Nature
, vol.400
, pp. 276-280
-
-
Tsuda, M.1
Kamimura, K.2
Nakato, H.3
-
67
-
-
45449112808
-
Nanoscale organization of hedgehog is essential for long-range signaling
-
Vyas, N., Goswami, D., Manonmani, A., et al. (2008). Nanoscale organization of hedgehog is essential for long-range signaling. Cell 133, 1214-1227.
-
(2008)
Cell
, vol.133
, pp. 1214-1227
-
-
Vyas, N.1
Goswami, D.2
Manonmani, A.3
-
68
-
-
0029096833
-
K-glypican: A novel GPI-linked heparan sulfate proteoglycan that is highly expressed in developing brain and kidney
-
Watanabe, K., Yamada, H., and Yamaguchi, Y. (1995). K-glypican: a novel GPI-linked heparan sulfate proteoglycan that is highly expressed in developing brain and kidney. J Cell Biol 130, 1207-1218.
-
(1995)
J Cell Biol
, vol.130
, pp. 1207-1218
-
-
Watanabe, K.1
Yamada, H.2
Yamaguchi, Y.3
-
69
-
-
77950538817
-
Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response
-
Williams, E. H., Pappano, W. N., Saunders, A. M., Kim, M. S., Leahy, D. J., and Beachy, P. A. (2010). Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response. Proc Natl Acad Sci U S A 107, 5869-5874.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 5869-5874
-
-
Williams, E.H.1
Pappano, W.N.2
Saunders, A.M.3
Kim, M.S.4
Leahy, D.J.5
Beachy, P.A.6
-
70
-
-
33846416922
-
Role for amplification and expression of glypican-5 in rhabdomyosarcoma
-
Williamson, D., Selfe, J., Gordon, T., et al. (2007). Role for amplification and expression of glypican-5 in rhabdomyosarcoma. Cancer Res 67, 57-65.
-
(2007)
Cancer Res
, vol.67
, pp. 57-65
-
-
Williamson, D.1
Selfe, J.2
Gordon, T.3
-
71
-
-
36549029368
-
Drosophila glypican Dally-like acts in FGF-receiving cells to modulate FGF signaling during tracheal morphogenesis
-
Yan, D., and Lin, X. (2007). Drosophila glypican Dally-like acts in FGF-receiving cells to modulate FGF signaling during tracheal morphogenesis. Dev Biol 312 (1), 203-216.
-
(2007)
Dev Biol
, vol.312
, Issue.1
, pp. 203-216
-
-
Yan, D.1
Lin, X.2
-
72
-
-
70349986968
-
The core protein of glypican Dally-like determines its biphasic activity in wingless morphogen signaling
-
Yan, D., Wu, Y., Feng, Y., Lin, S. C., and Lin, X. (2009). The core protein of glypican Dally-like determines its biphasic activity in wingless morphogen signaling. Dev Cell 17, 470-481.
-
(2009)
Dev Cell
, vol.17
, pp. 470-481
-
-
Yan, D.1
Wu, Y.2
Feng, Y.3
Lin, S.C.4
Lin, X.5
-
73
-
-
77953080875
-
The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development
-
Yan, D., Wu, Y., Yang, Y., Belenkaya, T. Y., Tang, X., and Lin, X. (2010). The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development. Development 137, 2033-2044.
-
(2010)
Development
, vol.137
, pp. 2033-2044
-
-
Yan, D.1
Wu, Y.2
Yang, Y.3
Belenkaya, T.Y.4
Tang, X.5
Lin, X.6
-
74
-
-
1842479155
-
Structural determinants of heparan sulfate interactions with Slit proteins
-
Zhang, F., Ronca, F., Linhardt, R. J., and Margolis, R. U. (2004). Structural determinants of heparan sulfate interactions with Slit proteins. Biochem Biophys Res Commun 317, 352-357.
-
(2004)
Biochem Biophys Res Commun
, vol.317
, pp. 352-357
-
-
Zhang, F.1
Ronca, F.2
Linhardt, R.J.3
Margolis, R.U.4
-
75
-
-
85081455461
-
A phase 1 study of GC33, a recombinant humanized antibody against glypican-3, in patients with advanced hepatocellular carcinoma
-
(abstr. 4085)
-
Zhu, A. X., Gold, P. J., El-Khoueiry, A. B., Abrams, T. A., Morikawa, H., and Philip, P. A. (2011). A phase 1 study of GC33, a recombinant humanized antibody against glypican-3, in patients with advanced hepatocellular carcinoma. J Clin Oncol 29 (Suppl., abstr. 4085).
-
(2011)
J Clin Oncol
, vol.29
-
-
Zhu, A.X.1
Gold, P.J.2
El-Khoueiry, A.B.3
Abrams, T.A.4
Morikawa, H.5
Philip, P.A.6
-
76
-
-
74949095496
-
Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo
-
Zittermann, S. I., Capurro, M. I., and Filmus, J. (2010). Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo. Int J Cancer 126, 1291-1301.
-
(2010)
Int J Cancer
, vol.126
, pp. 1291-1301
-
-
Zittermann, S.I.1
Capurro, M.I.2
Filmus, J.3
|