Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome

Journal of Cell Biology

Volumn 146, Issue 1, 1999, Pages 255-264

  Cano Gauci, Danielle F ^a,b   Song, Howard H ^b,c   Yang, Huiling ^b,c   McKerlie, Colin ^c   Choo, Barbara ^a,b   Shi, Wen ^b,c   Pullano, Rose ^a,b   Piscione, Tino D ^d   Grisaru, Silviu ^d   Soon, Shawn ^d   Sedlackova, Larisa ^d   Tanswell, A Keith ^d   Mak, Tak W ^a,e   Yeger, Herman ^d   Lockwood, Gina A ^a,b   Rosenblum, Norman D ^d   Filmus, Jorge ^b,c  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e AMGEN INSTITUTE   (Canada)

Author keywords

Glypican 3; Insulin like growth factor II; Kidney dysplasia; Overgrowth; Simpson Golabi Behmel syndrome

Indexed keywords

GLYPICAN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BECKWITH WIEDEMANN SYNDROME; DEVELOPMENTAL DISORDER; EMBRYO; GENE MUTATION; KIDNEY CYST; KIDNEY DYSPLASIA; KNOCKOUT MOUSE; MANDIBLE HYPOPLASIA; MOUSE; NONHUMAN; PERINATAL DEATH; PRIORITY JOURNAL; PROTEIN FAMILY; SIMPSON GOLABI BEHMEL SYNDROME; VAGINA ATRESIA;

ABNORMALITIES, MULTIPLE; ANIMALS; BECKWITH-WIEDEMANN SYNDROME; BODY WEIGHT; CELL DIVISION; FEMALE; GENOTYPE; GLYPICANS; GROWTH DISORDERS; HEPARAN SULFATE PROTEOGLYCANS; HEPARITIN SULFATE; HUMANS; INSULIN-LIKE GROWTH FACTOR II; KIDNEY TUBULES, COLLECTING; MALE; MANDIBLE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGAN SIZE; PHENOTYPE; PROTEOGLYCANS; SYNDROME;

ANIMALIA;

EID: 0033549528     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.146.1.255     Document Type: Article

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