Hepatitis B Virus Infection and Immunopathogenesis in a Humanized Mouse Model: Induction of Human-Specific Liver Fibrosis and M2-Like Macrophages

PLoS Pathogens

Volumn 10, Issue 3, 2014, Pages

  Bility, Moses T ^a   Cheng, Liang ^a   Zhang, Zheng ^b   Luan, Yan ^a,c,d   Li, Feng ^a   Chi, Liqun ^a   Zhang, Liguo ^c   Tu, Zhengkun ^a,e   Gao, Yanhang ^e   Fu, Yangxin ^c,d   Niu, Junqi ^e   Wang, Fusheng ^b   Su, Lishan ^a,c,e  

^a UNIVERSITY OF NORTH CAROLINA HOSPITALS   (United States)

^b BEIJING 302 HOSPITAL   (China)

^c INSTITUTE OF BIOPHYSICS   (China)

^d UNIVERSITY OF CHICAGO   (United States)

^e JILIN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; AMAC1 PROTEIN; CALGRANULIN B; CD163 ANTIGEN; CD68 ANTIGEN; COL1A1 PROTEIN; COLLAGEN; DECTIN 1; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN M ANTIBODY; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR ALPHA; INTERLEUKIN 12; INTERLEUKIN 12P40; INTERLEUKIN 6; JO 2 ANTIBODY; NEUTRALIZING ANTIBODY; PEPTIDES AND PROTEINS; PROTEIN ANTIBODY; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; V SET DOMAIN CONTAINING T CELL ACTIVATION INHIBITOR 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; HEPATITIS B; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; LIVER FAILURE; LIVER FIBROSIS; LIVER NECROSIS; MACROPHAGE; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; UPREGULATION;

ANIMALS; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEMATOPOIETIC STEM CELLS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HEPATOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER CIRRHOSIS; MACROPHAGES; MICE; MICE, INBRED NOD; STEM CELLS; TRANSPLANTATION, HETEROLOGOUS;

EID: 84897420281     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004032     Document Type: Article

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