In vitro Fab display: A cell-free system for IgG discovery

Protein Engineering, Design and Selection

Volumn 27, Issue 4, 2014, Pages 97-109

  Stafford, Ryan L ^a   Matsumoto, Marissa L ^a   Yin, Gang ^a   Cai, Qi ^a   Fung, Juan Jose ^a   Stephenson, Heather ^a   Gill, Avinash ^a   You, Monica ^a   Lin, Shwu Hwa ^a   Wang, Willie D ^a   Masikat, Mary Rose ^a   Li, Xiaofan ^a   Penta, Kalyani ^a   Steiner, Alex R ^a   Baliga, Ramesh ^a   Murray, Christopher J ^a   Thanos, Christopher D ^a,b   Hallam, Trevor J ^a   Sato, Aaron K ^a  

^a Sutro Biopharma Inc   (United States)

^b Halozyme Therapeutics Inc   (United States)

Author keywords

antibody reformatting; cell free protein synthesis; Fab selections; ribosome display

Indexed keywords

ANTIGENS; ENDOTHELIAL CELLS; MONOCLONAL ANTIBODIES; PROTEINS; PURIFICATION;

ANTIBODY FAB FRAGMENTS; CARCINOEMBRYONIC ANTIGEN; CELL FREE PROTEIN SYNTHESIS; CELL-FREE REACTIONS; FAB SELECTIONS; PROTEIN FRAGMENTS; RIBOSOME DISPLAY; VASCULAR ENDOTHELIAL GROWTH FACTOR;

CHAINS;

CARCINOEMBRYONIC ANTIGEN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; TRASTUZUMAB; VASCULOTROPIN; ANTIBODY; MONOCLONAL ANTIBODY; PEPTIDE LIBRARY; VASCULOTROPIN A;

ANTIBODY LIBRARY; ANTIBODY SCREENING; ANTIGEN BINDING; ARTICLE; CELL FREE SYSTEM; CONTROLLED STUDY; HEAVY CHAIN; IN VITRO STUDY; LIGHT CHAIN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIBOSOME; CELL SURFACE DISPLAY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; HUMAN; METABOLISM; PEPTIDE LIBRARY; PROCEDURES;

ANTIBODIES; ANTIBODIES, MONOCLONAL, HUMANIZED; CARCINOEMBRYONIC ANTIGEN; CELL SURFACE DISPLAY TECHNIQUES; CELL-FREE SYSTEM; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN G; PEPTIDE LIBRARY; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84897417686     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzu002     Document Type: Article

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