A potential CARB-pharmacophore for antineoplastic activity: Part 1

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 7, 2014, Pages 1752-1757

  Witczak, Zbigniew J ^a   Poplawski, Tomasz ^b   Czubatka, Anna ^b   Sarnik, Joanna ^b   Tokarz, Pawel ^b   Vanwert, Adam L ^a   Bielski, Roman ^a  

^a WILKES UNIVERSITY   (United States)

^b UNIVERSITY OF LODZ   (Poland)

Author keywords

2 C Methylene myo inositol oxide; Anhydro sugars; Cancer cell lines; CARB Pharmacophore; Thio sugars

Indexed keywords

1,5 ANHYDRO 6 DEOXY 6 METHANE SULFAMIDO DEXTRO GLUCITOL; 1,6 ANHYDRO 5 C HYDROXYMETHYL ALPHA ALTRO PYRANOSE; 2 C METHYLENE MYO INOSITOL OXIDE; ANTINEOPLASTIC AGENT; CARBOHYDRATE DERIVATIVE; FORMAZAN; KETOSE; THIOGLUCOSE; UNCLASSIFIED DRUG; CARBOHYDRATE; GLUCOSE; SUCROSE; SUGAR; THIOSUGAR; TREHALOSE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL PROLIFERATION; CELL VIABILITY; COLORIMETRY; CONFORMATION; CYTOTOXICITY; HUMAN; HUMAN CELL; HYDROGEN BOND; LIPOPHILICITY; LUNG ADENOCARCINOMA; MOLECULAR MODEL; PHARMACOPHORE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; HELA CELL LINE; K562 CELL LINE; MCF 7 CELL LINE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE; ANIMAL CELL; APOPTOSIS; CANCER CELL LINE; CELL CYCLE; CELLS BY BODY ANATOMY; CONTROLLED STUDY; FEMALE; INTESTINE FLUID; NONHUMAN;

ANTINEOPLASTIC AGENTS; CARBOHYDRATE CONFORMATION; CARBOHYDRATES; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; K562 CELLS; MCF-7 CELLS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84897413915     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.02.036     Document Type: Article

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