Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics

Drug Metabolism and Disposition

Volumn 41, Issue 4, 2013, Pages 791-800

  Wolman, Aaron T ^a   Gionfriddo, Michael R ^b   Heindel, Gregory A ^a   Mukhija, Paran ^a   Witkowski, Sarah ^a   Bommareddy, Ajay ^a   Vanwert, Adam L ^a  

^a WILKES UNIVERSITY   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 AMINOPENICILLANIC ACID; AMPICILLIN; AZLOCILLIN; AZTREONAM; BETA LACTAM ANTIBIOTIC; CARBENICILLIN; CEFACLOR; CEFADROXIL; CEFALEXIN; CEFALOTIN; CEFMETAZOLE; CEFOPERAZONE; CEFOTAXIME; CEFOXITIN; CEFSULODIN; CEFTAZIDIME; CEFTIOFUR; CEFUROXIME; CLOXACILLIN; DICLOXACILLIN; METICILLIN; NAFCILLIN; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 3; OXACILLIN; PENICILLIN G; PENICILLIN V; TAZOBACTAM; TICARCILLIN; UNINDEXED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG INTERACTION; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG TRANSPORT; EMBRYO; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROGEN BOND; LIPOPHILICITY; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURFACE PROPERTY;

ANIMALS; ANTI-BACTERIAL AGENTS; BETA-LACTAMS; BIOLOGICAL TRANSPORT; CELL LINE, TRANSFORMED; HUMANS; MICE; ORGANIC ANION TRANSPORT PROTEIN 1; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84875822465     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.112.049569     Document Type: Article

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