메뉴 건너뛰기




Volumn 63, Issue 23, 2006, Pages 2331-2338

Ranolazine in the management of chronic stable angina

Author keywords

Amlodipine; Angina; Atenolol; Blood levels; Cardiac drugs; Combined therapy; Diltiazem; Dosage; Drug interactions; Food; Mechanism of action; Pharmacokinetics; Ranolazine; Toxicity

Indexed keywords

AMIODARONE; AMLODIPINE; AMLODIPINE BESYLATE; ANTIANGINA PECTORIS AGENT; ATENOLOL; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; DIGOXIN; DILTIAZEM; FLECAINIDE; GLYCERYL TRINITRATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ION CHANNEL; KETOCONAZOLE; MACROLIDE; MOXIFLOXACIN; NITRIC ACID DERIVATIVE; PAROXETINE; PLACEBO; POTASSIUM CHANNEL BLOCKING AGENT; PROCAINAMIDE; PROTEINASE INHIBITOR; RANOLAZINE; SIMVASTATIN; SODIUM CHANNEL BLOCKING AGENT; SOTALOL; TRIMETAZIDINE; UNINDEXED DRUG; VERAPAMIL; ZIPRASIDONE;

EID: 33845214512     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.2146/ajhp060042     Document Type: Review
Times cited : (11)

References (51)
  • 2
    • 25444515953 scopus 로고    scopus 로고
    • ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure)
    • Developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society
    • Hunt SA, Abraham WT, Chin MH et al. ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation. 2005; 112:1825-52.
    • (2005) Circulation , vol.112 , pp. 1825-1852
    • Hunt, S.A.1    Abraham, W.T.2    Chin, M.H.3
  • 3
    • 2442674610 scopus 로고    scopus 로고
    • (accessed 2005 Sep 1)
    • American Heart Association. Heart disease and stroke statistics - 2005 update. www.americanheart.org/downloadable/heart/ 1105390918119HDSStats2005Update.pdf (accessed 2005 Sep 1).
    • Heart Disease and Stroke Statistics - 2005 Update
  • 4
    • 0037223522 scopus 로고    scopus 로고
    • The underutilization of cardiac medications of proven benefit, 1990 to 2002
    • Stafford RS, Radley DC. The underutilization of cardiac medications of proven benefit, 1990 to 2002. J Am Coll Cardiol. 2003; 41:56-61.
    • (2003) J Am Coll Cardiol , vol.41 , pp. 56-61
    • Stafford, R.S.1    Radley, D.C.2
  • 5
    • 0023720355 scopus 로고
    • Antarctic measurements of ozone by Sage-II in the spring of 1985, 1986, and 1987
    • McCormick MP, Larsen JC. Antarctic measurements of ozone by Sage-II in the spring of 1985, 1986, and 1987. Geophys Res Lett. 1988; 15:906-10.
    • (1988) Geophys Res Lett , vol.15 , pp. 906-910
    • McCormick, M.P.1    Larsen, J.C.2
  • 6
    • 0030698261 scopus 로고    scopus 로고
    • Underutilization of beta-blockers in older patients with prior myocardial infarction or coronary artery disease in an academic, hospital-based geriatrics practice
    • Mendelson G, Aronow WS. Underutilization of beta-blockers in older patients with prior myocardial infarction or coronary artery disease in an academic, hospital-based geriatrics practice. J Am Geriatr Soc. 1997; 45:1360-1.
    • (1997) J Am Geriatr Soc , vol.45 , pp. 1360-1361
    • Mendelson, G.1    Aronow, W.S.2
  • 7
    • 0036847929 scopus 로고    scopus 로고
    • Angina 1 year after percutaneous coronary intervention: A report from the NHLBI Dynamic Registry
    • Holubkov R, Laskey WK, Haviland A et al. Angina 1 year after percutaneous coronary intervention: a report from the NHLBI Dynamic Registry. Am Heart J. 2002; 144:826-33.
    • (2002) Am Heart J , vol.144 , pp. 826-833
    • Holubkov, R.1    Laskey, W.K.2    Haviland, A.3
  • 8
    • 0035849152 scopus 로고    scopus 로고
    • Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease
    • Serruys PW, Unger F, Sousa JE et al. Comparison of coronary-artery bypass surgery and stenting for the treatment of multivessel disease. N Engl J Med. 2001; 344:1117-24.
    • (2001) N Engl J Med , vol.344 , pp. 1117-1124
    • Serruys, P.W.1    Unger, F.2    Sousa, J.E.3
  • 9
    • 1842863476 scopus 로고    scopus 로고
    • Improvement of oxygen metabolism in ischemic myocardium as a result of enhanced external counterpulsation with heparin pretreatment for patients with stable angina
    • Masuda D, Fujita M, Nohara R et al. Improvement of oxygen metabolism in ischemic myocardium as a result of enhanced external counterpulsation with heparin pretreatment for patients with stable angina. Heart Vessels. 2004; 19:59-62.
    • (2004) Heart Vessels , vol.19 , pp. 59-62
    • Masuda, D.1    Fujita, M.2    Nohara, R.3
  • 10
    • 0032532690 scopus 로고    scopus 로고
    • Coronary blood flow dynamics during transcutaneous electrical nerve stimulation for stable angina pectoris associated with severe narrowing of one major coronary artery
    • Jessurun GA, Tio RA, De Jongste MJ et al. Coronary blood flow dynamics during transcutaneous electrical nerve stimulation for stable angina pectoris associated with severe narrowing of one major coronary artery. Am J Cardiol. 1998; 82:921-6.
    • (1998) Am J Cardiol , vol.82 , pp. 921-926
    • Jessurun, G.A.1    Tio, R.A.2    De Jongste, M.J.3
  • 11
    • 0022474975 scopus 로고
    • Transcutaneous electrical nerve stimulation (TENS) in angina pectoris
    • Mannheimer C, Carlsson CA, Vedin A et al. Transcutaneous electrical nerve stimulation (TENS) in angina pectoris. Pain. 1986; 26:291-300.
    • (1986) Pain , vol.26 , pp. 291-300
    • Mannheimer, C.1    Carlsson, C.A.2    Vedin, A.3
  • 12
    • 0037870485 scopus 로고    scopus 로고
    • Exercise capability and myocardial perfusion in chronic angina patients treated with enhanced external counterpulsation
    • Tartaglia J, Stenerson J Jr., Charney R et al. Exercise capability and myocardial perfusion in chronic angina patients treated with enhanced external counterpulsation. Clin Cardiol. 2003; 26:287-90.
    • (2003) Clin Cardiol , vol.26 , pp. 287-290
    • Tartaglia, J.1    Stenerson Jr., J.2    Charney, R.3
  • 13
    • 0032716497 scopus 로고    scopus 로고
    • The multicenter study of enhanced external counterpulsation (MUST-EECP): Effect of EECP on exercise induced myocardial ischemia and anginal episodes
    • Arora RR, Chou TM, Jain D et al. The multicenter study of enhanced external counterpulsation (MUST-EECP): effect of EECP on exercise induced myocardial ischemia and anginal episodes. J Am Coll Cardiol. 1999; 33:1833-40.
    • (1999) J Am Coll Cardiol , vol.33 , pp. 1833-1840
    • Arora, R.R.1    Chou, T.M.2    Jain, D.3
  • 14
    • 2342526006 scopus 로고    scopus 로고
    • Metabolic manipulation in ischaemic heart disease, a novel approach to treatment
    • Lee L, Horowitz J, Frenneaux M. Metabolic manipulation in ischaemic heart disease, a novel approach to treatment. Eur Heart J. 2004; 25:634-41.
    • (2004) Eur Heart J , vol.25 , pp. 634-641
    • Lee, L.1    Horowitz, J.2    Frenneaux, M.3
  • 15
    • 0003082107 scopus 로고
    • Fuels: Carbohydrates and lipids
    • Opie LH, ed. New York: Raven Press
    • Opie LH. Fuels: carbohydrates and lipids. In: Opie LH, ed. The heart: physiology and metabolism. New York: Raven Press; 1991:208-46.
    • (1991) The Heart: Physiology and Metabolism , pp. 208-246
    • Opie, L.H.1
  • 16
    • 0024267688 scopus 로고
    • Myocardial substrate utilization during exercise in humans. Dual carbon-labeled carbohydrate isotope experiments
    • Gertz EW, Wisneski JA, Stanley WC et al. Myocardial substrate utilization during exercise in humans. Dual carbon-labeled carbohydrate isotope experiments. J Clin Invest. 1988; 82:2017-25.
    • (1988) J Clin Invest , vol.82 , pp. 2017-2025
    • Gertz, E.W.1    Wisneski, J.A.2    Stanley, W.C.3
  • 17
    • 0036801431 scopus 로고    scopus 로고
    • Defective cardiac ion channels: From mutations to clinical syndromes
    • Clancy CE, Kass RS. Defective cardiac ion channels: from mutations to clinical syndromes. J Clin Invest. 2002; 110:1075-7.
    • (2002) J Clin Invest , vol.110 , pp. 1075-1077
    • Clancy, C.E.1    Kass, R.S.2
  • 18
    • 0033694833 scopus 로고    scopus 로고
    • From ionic currents to molecular mechanisms: The structure and function of voltage-gated sodium channels
    • Catterall WA. From ionic currents to molecular mechanisms: the structure and function of voltage-gated sodium channels. Neuron. 2000; 26:13-25.
    • (2000) Neuron , vol.26 , pp. 13-25
    • Catterall, W.A.1
  • 19
    • 85047676504 scopus 로고
    • Inhibition of sodium and calcium overload pathology in the myocardium: A new cytoprotective principle
    • Ver Donck L, Borgers M, Verdonck F. Inhibition of sodium and calcium overload pathology in the myocardium: a new cytoprotective principle. Cardiovasc Res. 1993; 27:349-57.
    • (1993) Cardiovasc Res , vol.27 , pp. 349-357
    • Ver Donck, L.1    Borgers, M.2    Verdonck, F.3
  • 20
    • 0028298795 scopus 로고
    • Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading
    • Haigney MC, Lakatta EG, Stern MD et al. Sodium channel blockade reduces hypoxic sodium loading and sodium-dependent calcium loading. Circulation. 1994; 90:391-9.
    • (1994) Circulation , vol.90 , pp. 391-399
    • Haigney, M.C.1    Lakatta, E.G.2    Stern, M.D.3
  • 21
    • 0026666057 scopus 로고
    • Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine
    • Undrovinas AI, Fleidervish IA, Makielski JC. Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine. Circ Res. 1992; 71:1231-41.
    • (1992) Circ Res , vol.71 , pp. 1231-1241
    • Undrovinas, A.I.1    Fleidervish, I.A.2    Makielski, J.C.3
  • 22
    • 0034666307 scopus 로고    scopus 로고
    • Induction of persistent sodium current by exogenous and endogenous nitric oxide
    • Ahern GP, Hsu SF, Klyachko VA et al. Induction of persistent sodium current by exogenous and endogenous nitric oxide. J Biol Chem. 2000; 275:28810-5.
    • (2000) J Biol Chem , vol.275 , pp. 28810-28815
    • Ahern, G.P.1    Hsu, S.F.2    Klyachko, V.A.3
  • 23
    • 0027925720 scopus 로고
    • Cardiac ion channels
    • Katz AM. Cardiac ion channels. N Engl J Med. 1993; 328:1244-51.
    • (1993) N Engl J Med , vol.328 , pp. 1244-1251
    • Katz, A.M.1
  • 24
    • 0033603309 scopus 로고    scopus 로고
    • Intracellular sodium accumulation during ischemia as the substrate for reperfusion injury
    • Imahashi K, Kusuoka H, Hashimoto K et al. Intracellular sodium accumulation during ischemia as the substrate for reperfusion injury. Circ Res. 1999; 84:1401-6.
    • (1999) Circ Res , vol.84 , pp. 1401-1406
    • Imahashi, K.1    Kusuoka, H.2    Hashimoto, K.3
  • 25
    • 0037376584 scopus 로고    scopus 로고
    • [Na+]i handling in the failing human heart
    • Pieske B, Houser SR. [Na+]i handling in the failing human heart. Cardiovasc Res. 2003; 57:874-86.
    • (2003) Cardiovasc Res , vol.57 , pp. 874-886
    • Pieske, B.1    Houser, S.R.2
  • 26
    • 0028990887 scopus 로고
    • 23Na and 31P nuclear magnetic resonance studies of ischemia-induced ventricular fibrillation. Alterations of intracellular Na+ and cellular energy
    • Pike MM, Luo CS, Yanagida S et al. 23Na and 31P nuclear magnetic resonance studies of ischemia-induced ventricular fibrillation. Alterations of intracellular Na+ and cellular energy. Circ Res. 1995; 77:394-406.
    • (1995) Circ Res , vol.77 , pp. 394-406
    • Pike, M.M.1    Luo, C.S.2    Yanagida, S.3
  • 27
    • 0028240843 scopus 로고
    • New Na(+)-H+ exchange inhibitor HOE 694 improves postischemic function and high-energy phosphate resynthesis and reduces Ca2+ overload in isolated perfused rabbit heart
    • Hendrikx M, Mubagwa K, Verdonck F et al. New Na(+)-H+ exchange inhibitor HOE 694 improves postischemic function and high-energy phosphate resynthesis and reduces Ca2+ overload in isolated perfused rabbit heart. Circulation. 1994; 89:2787-98.
    • (1994) Circulation , vol.89 , pp. 2787-2798
    • Hendrikx, M.1    Mubagwa, K.2    Verdonck, F.3
  • 28
    • 12744271862 scopus 로고    scopus 로고
    • Myocardial metabolic manipulation: A new therapeutic approach in heart failure?
    • O'Meara E, McMurray JJ. Myocardial metabolic manipulation: a new therapeutic approach in heart failure? Heart. 2005; 91:131-2.
    • (2005) Heart , vol.91 , pp. 131-132
    • O'Meara, E.1    McMurray, J.J.2
  • 29
    • 4344577023 scopus 로고    scopus 로고
    • Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties
    • Antzelevitch C, Belardinelli L, Zygmunt AC et al. Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties. Circulation. 2004; 110:904-10.
    • (2004) Circulation , vol.110 , pp. 904-910
    • Antzelevitch, C.1    Belardinelli, L.2    Zygmunt, A.C.3
  • 30
  • 31
    • 16844368625 scopus 로고    scopus 로고
    • Disposition of [14C]-ranolazine in humans
    • Abstract
    • Chu N, Lustig D, Wong S et al. Disposition of [14C]-ranolazine in humans. Drug Metab Rev. 2003; 35:49. Abstract.
    • (2003) Drug Metab Rev , vol.35 , pp. 49
    • Chu, N.1    Lustig, D.2    Wong, S.3
  • 32
    • 16844369128 scopus 로고    scopus 로고
    • Studies to investigate the pharmacokinetic interactions between ranolazine and ketoconazole, diltiazem, or simvastatin during combined administration in healthy subjects
    • Jerling M, Huan BL, Leung K et al. Studies to investigate the pharmacokinetic interactions between ranolazine and ketoconazole, diltiazem, or simvastatin during combined administration in healthy subjects. J Clin Pharmacol. 2005; 45:422-33.
    • (2005) J Clin Pharmacol , vol.45 , pp. 422-433
    • Jerling, M.1    Huan, B.L.2    Leung, K.3
  • 33
    • 18244401979 scopus 로고    scopus 로고
    • Combination treatment in stable effort angina using trimetazidine and metoprolol: Results of a randomized, double-blind, multicentre study (TRIMPOL II). TRIMetazidine in POLand
    • Szwed H, Sadowski Z, Elikowski W et al. Combination treatment in stable effort angina using trimetazidine and metoprolol: results of a randomized, double-blind, multicentre study (TRIMPOL II). TRIMetazidine in POLand. Eur Heart J. 2001; 22:2267-74.
    • (2001) Eur Heart J , vol.22 , pp. 2267-2274
    • Szwed, H.1    Sadowski, Z.2    Elikowski, W.3
  • 34
    • 0037732581 scopus 로고    scopus 로고
    • Efficacy and tolerability of trimetazidine in stable angina: A meta-analysis of randomized, double-blind, controlled trials
    • Marzilli M, Klein WW. Efficacy and tolerability of trimetazidine in stable angina: a meta-analysis of randomized, double-blind, controlled trials. Coron Artery Dis. 2003; 14:171-9.
    • (2003) Coron Artery Dis , vol.14 , pp. 171-179
    • Marzilli, M.1    Klein, W.W.2
  • 35
    • 0142057094 scopus 로고    scopus 로고
    • Impact of angina burden and other factors on treatment satisfaction after acute coronary syndromes
    • Beinart SC, Sales AE, Spertus JA et al. Impact of angina burden and other factors on treatment satisfaction after acute coronary syndromes. Am Heart J. 2003; 146:646-52.
    • (2003) Am Heart J , vol.146 , pp. 646-652
    • Beinart, S.C.1    Sales, A.E.2    Spertus, J.A.3
  • 37
    • 0028016058 scopus 로고
    • Double-blind efficacy and safety study of a novel anti-ischemic agent, ranolazine, versus placebo in patients with chronic stable angina pectoris
    • Thadani U, Ezekowitz M, Fenney L et al. Double-blind efficacy and safety study of a novel anti-ischemic agent, ranolazine, versus placebo in patients with chronic stable angina pectoris. Circulation. 1994; 90:726-34.
    • (1994) Circulation , vol.90 , pp. 726-734
    • Thadani, U.1    Ezekowitz, M.2    Fenney, L.3
  • 38
    • 0025217267 scopus 로고
    • Ranolazine (RS-43285): A preliminary study of a new anti-anginal agent with selective effect on ischaemic myocardium
    • Jain D, Dasgupta P, Hughes LO et al. Ranolazine (RS-43285): a preliminary study of a new anti-anginal agent with selective effect on ischaemic myocardium. Eur J Clin Pharmacol. 1990; 38:111-4.
    • (1990) Eur J Clin Pharmacol , vol.38 , pp. 111-114
    • Jain, D.1    Dasgupta, P.2    Hughes, L.O.3
  • 39
    • 11144356285 scopus 로고    scopus 로고
    • Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina
    • Chaitman BR, Skettino SL, Parker JO et al. Anti-ischemic effects and long-term survival during ranolazine monotherapy in patients with chronic severe angina. J Am Coll Cardiol. 2004; 43:1375-82.
    • (2004) J Am Coll Cardiol , vol.43 , pp. 1375-1382
    • Chaitman, B.R.1    Skettino, S.L.2    Parker, J.O.3
  • 40
    • 0026680239 scopus 로고
    • Effects of a new metabolic modulator, ranolazine, on exercise tolerance in angina pectoris patients treated with beta-blocker or diltiazem
    • Cocco G, Rousseau MF, Bouvy T et al. Effects of a new metabolic modulator, ranolazine, on exercise tolerance in angina pectoris patients treated with beta-blocker or diltiazem. J Cardiovasc Pharmacol. 1992; 20:131-8.
    • (1992) J Cardiovasc Pharmacol , vol.20 , pp. 131-138
    • Cocco, G.1    Rousseau, M.F.2    Bouvy, T.3
  • 41
    • 0032983310 scopus 로고    scopus 로고
    • A controlled trial with a novel anti-ischemic agent, ranolazine, in chronic stable angina pectoris that is responsive to conventional anti-anginal agents
    • Pepine CJ, Wolff AA. A controlled trial with a novel anti-ischemic agent, ranolazine, in chronic stable angina pectoris that is responsive to conventional anti-anginal agents. Am J Cardiol. 1999; 84:46-50.
    • (1999) Am J Cardiol , vol.84 , pp. 46-50
    • Pepine, C.J.1    Wolff, A.A.2
  • 42
    • 0348129532 scopus 로고    scopus 로고
    • Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: A randomized controlled trial
    • Chaitman BR, Pepine CJ, Parker JO et al. Effects of ranolazine with atenolol, amlodipine, or diltiazem on exercise tolerance and angina frequency in patients with severe chronic angina: a randomized controlled trial. JAMA. 2004; 291:309-16.
    • (2004) JAMA , vol.291 , pp. 309-316
    • Chaitman, B.R.1    Pepine, C.J.2    Parker, J.O.3
  • 43
    • 0030043641 scopus 로고    scopus 로고
    • Measuring heart patients' willingness to pay for changes in angina symptoms
    • Chestnut LG, Keller LR, Lambert WE et al. Measuring heart patients' willingness to pay for changes in angina symptoms. Med Decis Making. 1996; 16:65-77.
    • (1996) Med Decis Making , vol.16 , pp. 65-77
    • Chestnut, L.G.1    Keller, L.R.2    Lambert, W.E.3
  • 44
    • 0029807227 scopus 로고    scopus 로고
    • Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: A comparative study of the efficacy and safety against amlodipine
    • Corea L, Cardoni O, Fogari R et al. Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: a comparative study of the efficacy and safety against amlodipine. Clin Parmacol Ther. 1996; 60:341-6.
    • (1996) Clin Parmacol Ther , vol.60 , pp. 341-346
    • Corea, L.1    Cardoni, O.2    Fogari, R.3
  • 45
    • 33645796498 scopus 로고    scopus 로고
    • Anti-anginal efficacy of ranolazine when added to maximal conventional therapy: The efficacy of ranolazine in chronic angina therapy
    • Abstract
    • Stone PH, Gratsiansky NA, Blokhin A et al. Anti-anginal efficacy of ranolazine when added to maximal conventional therapy: the efficacy of ranolazine in chronic angina therapy. Circulation. 2005; 112:11-748. Abstract.
    • (2005) Circulation , vol.112 , pp. 11-748
    • Stone, P.H.1    Gratsiansky, N.A.2    Blokhin, A.3
  • 46
    • 12844280008 scopus 로고    scopus 로고
    • Comparative efficacy of ranolazine versus atenolol for chronic angina pectoris
    • Rousseau MF, Pouleur H, Cocco G et al. Comparative efficacy of ranolazine versus atenolol for chronic angina pectoris. Am J Cardiol. 2005; 95:311-6.
    • (2005) Am J Cardiol , vol.95 , pp. 311-316
    • Rousseau, M.F.1    Pouleur, H.2    Cocco, G.3
  • 47
    • 0030058329 scopus 로고    scopus 로고
    • Diurnal pattern of QTc interval: How long is prolonged? Possible relation to circadian triggers of cardiovascular events
    • Molnar J, Zhang F, Weiss J et al. Diurnal pattern of QTc interval: how long is prolonged? Possible relation to circadian triggers of cardiovascular events. J Am Coll Cardiol. 1996; 27:76-83.
    • (1996) J Am Coll Cardiol , vol.27 , pp. 76-83
    • Molnar, J.1    Zhang, F.2    Weiss, J.3
  • 50
    • 21044458297 scopus 로고    scopus 로고
    • Effect of hepatic impairment on the multiple-dose pharmacokinetics of ranolazine sustained-release tablets
    • Abdallah H, Jerling M. Effect of hepatic impairment on the multiple-dose pharmacokinetics of ranolazine sustained-release tablets. J Clin Pharmacol. 2005; 45:802-9.
    • (2005) J Clin Pharmacol , vol.45 , pp. 802-809
    • Abdallah, H.1    Jerling, M.2
  • 51
    • 28944448286 scopus 로고    scopus 로고
    • Effects of ranolazine on exercise tolerance and HbA1c in patients with chronic angina and diabetes
    • Timmis AD, Chaitman BR, Crager M. Effects of ranolazine on exercise tolerance and HbA1c in patients with chronic angina and diabetes. Eur Heart J. 2006; 27:42-8.
    • (2006) Eur Heart J , vol.27 , pp. 42-48
    • Timmis, A.D.1    Chaitman, B.R.2    Crager, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.